Effect of pretreatment with oral pyridostigmine on subsequent activity of alcuronium in non-anaesthetized subjects.

abstract：BACKGROUND:Positive end-expiratory pressure (PEEP) is widely used to improve oxygenation and prevent alveolar collapse in mechanically ventilated patients with the acute respiratory distress syndrome (ARDS). Although PEEP improves arterial oxygenation predictably, high-PEEP strategies have demonstrated equivocal improv...

journal_title：British journal of anaesthesia

authors： Chikhani M,Das A,Haque M,Wang W,Bates DG,Hardman JG

更新日期：2016-11-01 00:00:00

abstract：:The Walton-Brodie strain gauge arch is an instrument that quantitatively measures CF. Like many methods, the strain gauge arch is affected by loading conditions and heart rate. Nevertheless, this methodology, when properly used, has proved very useful in describing the direct action of anaesthetic drugs. Knowledge fro...

journal_title：British journal of anaesthesia

authors： Reves JG,Pruett JK

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Aortocaval compression (ACC) can result in haemodynamic disturbances and uteroplacental hypoperfusion in parturients. Its detection is difficult because in most patients, sympathetic compensation results in no signs or symptoms. However, profound hypotension may develop after sympathectomy during regional an...

journal_title：British journal of anaesthesia

authors： Lee SW,Khaw KS,Ngan Kee WD,Leung TY,Critchley LA

更新日期：2012-12-01 00:00:00

abstract：:We have compared the anaesthetic and analgesic efficacy of levobupivacaine with that of racemic bupivacaine in 66 male patients undergoing ambulatory primary inguinal herniorrhaphy. Patients were allocated randomly in a double-blind manner to local infiltration anaesthesia (0.25% w/v 50 ml) with either racemic bupivac...

journal_title：British journal of anaesthesia

authors： Bay-Nielsen M,Klarskov B,Bech K,Andersen J,Kehlet H

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The ProSeal laryngeal mask airway (PLMA) is a new laryngeal mask device with a modified cuff and a drainage tube. METHODS:We assessed the PLMA in 300 anaesthetized adults either paralysed or breathing spontaneously. We assessed insertion characteristics, airway seal pressures, haemodynamic response to inser...

journal_title：British journal of anaesthesia

authors： Evans NR,Gardner SV,James MF,King JA,Roux P,Bennett P,Nattrass R,Llewellyn R,Visu D

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:The Laryngeal Tube (LT) performs similarly to the classic laryngeal mask airway during controlled ventilation but with an improved airway seal. We compared the laryngeal tube with the ProSeal laryngeal mask airway (PLMA) throughout anaesthesia. METHODS:Thirty-two patients were studied using a randomized cro...

journal_title：British journal of anaesthesia

authors： Cook TM,McKinstry C,Hardy R,Twigg S

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The Alaris AEP monitor(TM) (Alaris, UK, version 1.4) is the first commercially available auditory evoked potential (AEP) monitor designed to estimate the depth of anaesthesia. It generates an "Alaris AEP index" (AAI), which is a dimensionless number scaled from 100 (awake) to 0. This study was designed to co...

journal_title：British journal of anaesthesia

authors： Kreuer S,Bruhn J,Larsen R,Hoepstein M,Wilhelm W

更新日期：2003-09-01 00:00:00

abstract：:A randomized, double-blind study of 38 patients undergoing total knee replacement was undertaken to compare the efficacy and respiratory effects of low-dose spinal morphine and patient-controlled i.v. morphine against patient-controlled i.v. morphine alone. Patients received either morphine 0.3 mg or saline 0.3 ml wit...

journal_title：British journal of anaesthesia

authors： Cole PJ,Craske DA,Wheatley RG

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The usefulness of the PFA-100 in assessing the risk of bleeding in non-cardiac surgery is not clear. This study aims to examine this by correlating preoperative PFA-100 measurement with perioperative bleeding in patients receiving cyclooxygenase (COX) inhibitors. METHODS:PFA-100 with adenosine-5'-diphosphat...

journal_title：British journal of anaesthesia

authors： Ng KF,Lawmin JC,Tsang SF,Tang WM,Chiu KY

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Current guidelines for perioperative management of coronavirus disease 19 (COVID-19) are mainly based on extrapolated evidence or expert opinion. We aimed to systematically investigate how COVID-19 affects perioperative management and clinical outcomes, to develop evidence-based guidelines. METHODS:First, w...

journal_title：British journal of anaesthesia

authors： Zheng H,Hébert HL,Chatziperi A,Meng W,Smith BH,Yan J,Zhou Z,Zhang X,Luo A,Wang L,Zhu W,Hu J,Colvin LA

更新日期：2020-12-01 00:00:00

abstract：:We studied 52 adults undergoing elective craniotomy, allocated randomly to one of three opioid treatments: alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 until dural closure (group Alf.); alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 for 2 h, then remifentanil 0.25 microgra...

journal_title：British journal of anaesthesia

authors： Sneyd JR,Whaley A,Dimpel HL,Andrews CJ

更新日期：1998-09-01 00:00:00

abstract：:Units for the investigation of susceptibility to malignant hyperthermia (MH) were set up in Denmark in 1977 and in Sweden in 1981. Two hundred and ten patients from 76 families have been investigated. The diagnosis of MH susceptibility (MHS) was made by in vitro exposure of muscle from vastus medialis to halothane and...

journal_title：British journal of anaesthesia

authors： Ording H,Ranklev E,Fletcher R

更新日期：1984-11-01 00:00:00

abstract：:Twenty consecutive patients undergoing cardiac surgery with cardiopulmonary bypass (CPB) were allocated at random to group 1 (n = 10, high inspired oxygen fraction (FIO2) after CPB), or group 2 (n = 10, moderate FIO2 after CPB). The effects of each FIO2 on arterial and mixed venous concentrations of endothelin-1 (ET-1...

journal_title：British journal of anaesthesia

authors： Reber A,Budmiger B,Wenk M,Haefeli WE,Wolff T,Bein T,Skarvan K

更新日期：2000-05-01 00:00:00

abstract：:A variant of a rebreathing/indicator-dilution technique was used to measure lung volume. Two or three indicators, which should have essentially the same pulmonary volume of distribution, were used. Gas compositions were measured by respiratory mass spectrometry and an extrapolation was used to allow for oxygen consump...

journal_title：British journal of anaesthesia

authors： Black AM,Hahn CE,Maynard P,Scott IL

更新日期：1984-03-01 00:00:00

abstract：:We have studied the efficacy of preoxygenation using the Triservice Anaesthetic Apparatus (TSA) in healthy patients and found it to be unsatisfactory. An alternative technique suitable for field use was explored. The Mapleson D system (Bain) was found to be suitable for preoxygenation with a fresh gas flow of only 4 l...

journal_title：British journal of anaesthesia

authors： Lowe DM,McFadzean W

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Target-controlled infusion (TCI) systems use pharmacokinetic (PK) models to predict the drug infusion rates necessary to achieve a desired target plasma or effect-site concentration. As new PK models are developed and implemented in TCI systems, there can be uncertainty as to which target concentrations are ...

journal_title：British journal of anaesthesia

authors： Eleveld DJ,Colin P,Absalom AR,Struys MMRF

更新日期：2020-10-01 00:00:00

abstract：:Gas injection systems used in several techniques of ventilation cause increases in airway pressure and physiological changes which are frequently overlooked. The momentum flux theory describes such phenomena most appropriately. We have defined and measured the characteristics of such increases in airway pressure, usin...

journal_title：British journal of anaesthesia

authors： Isabey D,Boussignac G,Harf A

更新日期：1989-01-01 00:00:00

abstract：:In rats injected s.c. with formalin, behavioural correlates of the amount and pattern of Fos-like immunoreactivity (Fos-Ll) (molecular responses to pain) were studied to test if early phase treatment with 75% nitrous oxide or 2% halothane, or both, suppressed subsequent spinal sensitization. Rats were allocated to fou...

journal_title：British journal of anaesthesia

authors： Sun WZ,Shyu BC,Shieh JY

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:The ultrasound cardiac output monitor (USCOM) is a continuous wave Doppler system designed to measure cardiac output (CO) non-invasively and intermittently either from the pulmonary or from the aortic valve. USCOM scan quality is critical to obtaining reliable data and during anaesthesia it is said to deteri...

journal_title：British journal of anaesthesia

authors： Huang L,Critchley LA

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The objective of this study was to develop a pharmacokinetic (PK) model to characterize the influence of obesity on propofol PK parameters. METHODS:Nineteen obese ASA II patients undergoing bariatric surgery were studied. Patients received propofol 2 mg kg(-1) bolus dose followed by a 5-20-40-120 min, 10-8-...

journal_title：British journal of anaesthesia

authors： Cortínez LI,Anderson BJ,Penna A,Olivares L,Muñoz HR,Holford NH,Struys MM,Sepulveda P

更新日期：2010-10-01 00:00:00

abstract：:The effects of laudanosine, a metabolite of atracurium, on the behaviour of conscious mice, rats and dogs, and on cardiovascular function in conscious and anaesthetized dogs have been evaluated: EEG studies were performed in anaesthetized dogs. In mice and rats, i.v. bolus doses of laudanosine 10-20 mg kg-1, caused co...

journal_title：British journal of anaesthesia

authors： Chapple DJ,Miller AA,Ward JB,Wheatley PL

更新日期：1987-02-01 00:00:00

abstract：:An extradural catheter was inserted at the third lumbar interspace for relief of pain during labour in a 21-year-old gravid patient. Attempts to withdraw the catheter met with resistance and produced severe pain in the distribution of the second left lumbar nerve. Radiography revealed an acutely angled loop of the cat...

journal_title：British journal of anaesthesia

authors： Sidhu MS,Asrani RV,Bassell GM

更新日期：1983-05-01 00:00:00

abstract：:Metoclopramide hastens emptying of the stomach. Since it may be given to patients before operation, the sedative and toxic effects of 10- and 20-mg does given i.m. were studied in patients and student volunteers. Saline and diazepam 10 mg were used as placebo and reference drugs. Neither dose of metoclopramide had as ...

journal_title：British journal of anaesthesia

authors： Dundee JW,Clarke RS,Howard PJ

更新日期：1974-07-01 00:00:00

abstract：BACKGROUND:Using a carrageenan inflammation rat model, we evaluated two experimental approaches to prolong sciatic nerve block on contralateral hyperalgesia. Method. We performed ipsilateral sciatic nerve block on the inflamed hind paw with bupivacaine-loaded microspheres suspended in dexamethasone (bupivacaine 12.5 mg...

journal_title：British journal of anaesthesia

authors： Estebe JP,Gentili ME,Le Corre P,Leduc C,Moulinoux JP,Ecoffey C

更新日期：2004-11-01 00:00:00

abstract：:The trachea of a man who had cut his own throat was successfully intubated using a fibreoptic laryngoscope after attempts at conventional oral intubation had failed. The advantages of the fibreoptic instrument and the method of use in such an injury are discussed. ...

journal_title：British journal of anaesthesia

authors： Davies JR

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which reflect spinal excitability, has been shown for propofol. We have assessed the concentration-dependent F-wave suppression by propofol and related it to th...

journal_title：British journal of anaesthesia

authors： Baars JH,Tas S,Herold KF,Hadzidiakos DA,Rehberg B

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Some anaesthetic agents exhibit an age-dependent analgesic effect, for example nitrous oxide, which is ineffective in newborn rats. We investigated whether a similar time dependency existed for the responses to the volatile anaesthetic isoflurane. METHODS:The analgesic and hypnotic properties of isoflurane ...

journal_title：British journal of anaesthesia

authors： Sanders RD,Patel N,Hossain M,Ma D,Maze M

更新日期：2005-09-01 00:00:00

abstract：:We evaluated prospectively the use of Gram staining of protected pulmonary specimens to allow the early diagnosis of ventilator-associated pneumonia (VAP), compared with the use of 60 bronchoscopic protected specimen brushes (PSB) and 126 blinded plugged telescopic catheters (PTC) obtained from 134 patients. Gram stai...

journal_title：British journal of anaesthesia

authors： Mimoz O,Karim A,Mazoit JX,Edouard A,Leprince S,Nordmann P

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Normalization of plasma fibrinogen levels may be associated with satisfactory haemostasis and reduced bleeding. The aim of this retrospective study was to assess fibrinogen recovery parameters after administration of fibrinogen concentrate (Haemocomplettan P) to patients with diffuse bleeding in cardiovascul...

journal_title：British journal of anaesthesia

authors： Solomon C,Pichlmaier U,Schoechl H,Hagl C,Raymondos K,Scheinichen D,Koppert W,Rahe-Meyer N

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:One major risk factor of the sitting position for neurosurgery is air embolism, especially in patients with persistent foramen ovale (PFO). The first aim of this prospective study was to evaluate a bedside method for detecting PFO using transcranial Doppler sonography (TCD) with contrast medium. A second aim...

journal_title：British journal of anaesthesia

authors： Engelhardt M,Folkers W,Brenke C,Scholz M,Harders A,Fidorra H,Schmieder K

更新日期：2006-04-01 00:00:00