Abstract:
:We have studied the efficacy of preoxygenation using the Triservice Anaesthetic Apparatus (TSA) in healthy patients and found it to be unsatisfactory. An alternative technique suitable for field use was explored. The Mapleson D system (Bain) was found to be suitable for preoxygenation with a fresh gas flow of only 4 litre of oxygen per minute. In a randomized study using only 4 litre of oxygen per minute for 3 min, the Bain system was found to be superior to the TSA.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Lowe DM,McFadzean Wdoi
10.1093/bja/66.2.196subject
Has Abstractpub_date
1991-02-01 00:00:00pages
196-9issue
2eissn
0007-0912issn
1471-6771pii
S0007-0912(17)48204-3journal_volume
66pub_type
临床试验,杂志文章,随机对照试验abstract:BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,meta分析
doi:10.1016/j.bja.2020.01.027
更新日期:2020-06-01 00:00:00
abstract::The pharmacokinetics of edrophonium were determined in patients anaesthetized with nitrous oxide and halothane undergoing kidney transplant nephrectomy (n=6) or transplantation of a live related donor kidney (n = 6). Serum concentrations of edrophonium were assayed by high pressure liquid chromatography and pharmacoki...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/53.12.1311
更新日期:1981-12-01 00:00:00
abstract::We have examined the effects of the highly selective alpha 2-adrenoceptor agonist, dexmedetomidine, on noradrenaline release and cell firing in isolated, superfused slices of rat locus coeruleus. Dexmedetomidine decreased both noradrenaline release and cell firing rate in a concentration-dependent fashion, with an EC5...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/71.3.447
更新日期:1993-09-01 00:00:00
abstract::We have measured plasma concentrations of bupivacaine after ilioinguinal block in children of different sizes. We studied 14 children with weights 10-15 kg and 17 children with weights 15-30 kg. Each child received 0.5% bupivacaine 0.25 ml kg-1 (1.25 mg kg-1) (Carbostesin, Astra, Germany). Venous blood was obtained be...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/76.3.452
更新日期:1996-03-01 00:00:00
abstract::The effects of the i.v. infusion of insulin, 70 mu. kg-1h-1 for the first 60 min and 35 mu. kg-1h-1 subsequently, on the metabolic and endocrine responses to gynaecological surgery were investigated. In comparison with a control group of patients, the insulin infusion caused a marked decrease in circulating glucose, n...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/55.10.939
更新日期:1983-10-01 00:00:00
abstract:BACKGROUND:The cuff pressures may be different in oesophageal and tracheal intubations. We conducted a study to evaluate if cuff pressures of endotracheal tubes (ETTs) could provide information to distinguish tracheal or oesophageal intubations in a pig trachea-oesophagus model. METHODS:In each preparation of pig trac...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aem244
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:The surgical pleth index (SPI) is a measurement of intraoperative nociception. Evidence of its usability in children is limited. Given that the autonomic nervous system is still developing during the first years of life, the performance of the SPI on small children cannot be concluded from studies carried ou...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1093/bja/aew215
更新日期:2016-09-01 00:00:00
abstract::Cobra venom consists of a neurotoxin which is responsible for respiratory paralysis simulating that associated with a non-depolarizing muscle relaxant. A combination of artificial respiration and neostigmine has been useful in resuscitating a child bitten by a snake. ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/49.10.1065
更新日期:1977-10-01 00:00:00
abstract::Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/62.2.194
更新日期:1989-02-01 00:00:00
abstract:BACKGROUND:The use of lipid emulsions to reduce cardiac toxicity of local anaesthetics (LAs) has shown success in experimental studies and some clinical cases, and thus has been implemented in clinical practice. However, lipid treatment is usually given after the occurrence of neurological or cardiovascular symptoms of...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aet353
更新日期:2014-04-01 00:00:00
abstract::The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally painful orthopaedic hand surgery (trapeziectomy). Further investigations revealed a lifelong history...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1016/j.bja.2019.02.019
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:The safe performance of regional anaesthesia (RA) requires theoretical knowledge and good manual skills. Virtual reality (VR)-based simulators may offer trainees a safe environment to learn and practice different techniques. However, currently available VR simulators do not consider individual anatomy, which...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aep224
更新日期:2009-10-01 00:00:00
abstract::Volume loading with crystalloid solution results in more pronounced haemodilution in patients who develop arterial hypotension during induction of extradural anaesthesia than in those who remain normotensive. The aim of this study was to describe the time course of this increase in haemodilution. Heart rate, systolic ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/77.2.223
更新日期:1996-08-01 00:00:00
abstract::We report a case of improved cardiopulmonary exercise (CPX) test outcomes measured 48 h after initial CPX testing and immediately after alterations were made to the settings of a dual chamber, dual sensing pacemaker with exercise detection. The changes allowed successful abdominal surgery to be completed. ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aet587
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:The effects of thoracic epidural anaesthesia (TEA) on gastric mucosal microvascular haemoglobin oxygenation (microHbO(2)) are unclear. At the splanchnic level, reduction of sympathetic tone may promote vasodilation and increase microHbO(2). However, these splanchnic effects are counteracted by systemic effec...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aeh235
更新日期:2004-10-01 00:00:00
abstract::Muscle fasciculations and pain following the administration of suxamethonium were assessed in a group of patients who performed a series of stretch exercises approximately 1 h before operation. Comparison was made with a group who received suxamethonium but no pretreatment. Fasciculations were significantly reduced in...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/59.5.596
更新日期:1987-05-01 00:00:00
abstract:INTRODUCTION:In the context of an increasing number of publications of trial data analysed by Bayesian methods, clinicians need support to better understand Bayesian statistical methods. The existing checklists are intended for people who already know these methods. We aimed to establish and validate a checklist that c...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1016/j.bja.2020.04.093
更新日期:2020-08-01 00:00:00
abstract::Effects of ageing were studied on the neural blockade and the pharmacokinetics after subarachnoid administration of 0.5% bupivacaine 3 ml in 8% glucose in two groups of 15 male patients, between 20 and 55 yr and older than 55 yr, respectively. The blockade was performed with the patient in the sitting position. Two mi...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/60.2.187
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:Patients undergoing non-cardiac, non-vascular surgery are at risk of major cardiovascular complications. In non-cardiac surgery, troponin elevation has previously been shown to be an independent predictor of major adverse cardiac events and postoperative mortality; however, a majority of studies have focused...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,meta分析,评审
doi:10.1093/bja/aew321
更新日期:2016-11-01 00:00:00
abstract::Control measurements of blood flow through and cefoxitin extraction ratios across heart and lungs, liver, kidneys and gut were made under steady-state conditions in awake unrestrained sheep. The studies then were repeated with the same animals anaesthetized with 1.5% halothane or whilst undergoing high thoracic (to ap...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/57.12.1239
更新日期:1985-12-01 00:00:00
abstract::We studied 40 elderly patients undergoing cataract surgery. Ten non-insulin-dependent diabetes mellitus (NIDDM) patients received standardized general anaesthesia, 10 NIDDM patients received local anaesthesia using retrobulbar block, 10 non-diabetic control patients received general anaesthesia and 10 non-diabetic con...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/74.5.500
更新日期:1995-05-01 00:00:00
abstract::Purified serum cholinesterase 90 mg was administered to a patient with cholinesterase deficiency. The effect on the action of suxamethonium was studied. The half-life (44.7 h), time constant (64.5 h), rate constant (0.0155 h-1) and distribution volume (2740 ml) of the cholinesterase activity were determined. ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/49.3.269
更新日期:1977-03-01 00:00:00
abstract:BACKGROUND:Data on bupivacaine concentrations in the cerebral spinal fluid (CSF) during spinal anaesthesia are scarce. The purpose of this study was to determine the concentration of bupivacaine in the lumbar CSF of patients with an adequate level of spinal anaesthesia after injection of plain bupivacaine 0.5%. METHOD...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aep049
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Miller laryngoscope blades are preferred for laryngoscopy in infants and children <2 yr of age. Despite their long history, the laryngeal view with the Miller blade size 1 has never been compared with that with the Macintosh (MAC) blade in children. This prospective, single-blinded, randomized study was desi...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1093/bja/aeu228
更新日期:2014-11-01 00:00:00
abstract::Eight patients with a history of failed tracheal intubation during pregnancy were investigated by x-ray laryngoscopy after delivery. Partial elevation of the epiglottis with no view of glottic structures was found in five patients who were therefore considered to still present difficulty. In each of these five patient...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/65.6.813
更新日期:1990-12-01 00:00:00
abstract:BACKGROUND:The objective of this study was to test whether non-invasive assessment of respiratory stroke volume variation (ΔrespSV) by oesophageal Doppler monitoring (ODM) can predict fluid responsiveness during surgery in a mixed population. The predictive value of ΔrespSV was evaluated using a grey zone approach. ME...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aes301
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Thermal, mechanical, and electrical stimuli are often used in acute pain studies and cause qualitatively different pain sensations. Yet, the comparative electroencephalogram (EEG) changes caused by these stimuli have not been studied. We hypothesized that because these stimuli cause different pain sensations...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/ael377
更新日期:2007-03-01 00:00:00
abstract:Background.:Perioperative administration of cefazolin reduces the incidence of perioperative infections. Intraoperative re-dosing of cefazolin is commonly given between 2 and 5 h after the initial dose. This study was undertaken to determine whether intraoperative continuous infusions of cefazolin achieve better probab...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1093/bja/aex026
更新日期:2017-06-01 00:00:00
abstract::Sickle cell disease is a congenital haemoglobinopathy with a high incidence of perioperative complications. Traditional anaesthetic management, based largely on extrapolation from biochemical models, has emphasized avoidance of red cell sickling to prevent exacerbations of the disease. This historical review outlines ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,评审
doi:10.1093/bja/aei129
更新日期:2005-09-01 00:00:00
abstract::Twelve hydrocephalic patients undergoing hydrodynamic studies and shunt procedures during general anaesthesia were subjected to short term observations of the cerebrovascular effects of isoflurane. Intraventricular pressure (IVP), arterial pressure (AP); cerebral perfusion pressure (CPP = AP-IVP), end-tidal PCO2, Cere...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/59.10.1208
更新日期:1987-10-01 00:00:00