Low-dose insulin infusion and substrate mobilization during surgery.

abstract：BACKGROUND:Pulse pressure variation (PPV) and stroke volume variation (SVV) are robust indicators of fluid responsiveness in mechanically ventilated supine patients. The aim of the study was to evaluate the ability of PPV and SVV to predict fluid responsiveness in mechanically ventilated patients in the prone position ...

journal_title：British journal of anaesthesia

authors： Biais M,Bernard O,Ha JC,Degryse C,Sztark F

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Emotional information has the ability to alter the formation and strength of a memory ('memory modulation'). Memory modulation by negative emotion is mediated by the amygdala. It is not known how gamma aminobutyric acid (GABA)ergic drugs affect the processes involved in memory modulation. This study investig...

journal_title：British journal of anaesthesia

authors： Pryor KO,Veselis RA,Reinsel RA,Feshchenko VA

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:As 6% hydroxyethyl starch (HES) 130/0.40 or 130/0.42 can originate from different vegetable sources, they might have different clinical effects. The purpose of this prospective, randomized, double-blind controlled trial was to compare two balanced tetrastarch solutions, one maize-derived and one potato-deriv...

journal_title：British journal of anaesthesia

authors： Joosten A,Tircoveanu R,Arend S,Wauthy P,Gottignies P,Van der Linden P

更新日期：2016-10-01 00:00:00

abstract：:We have studied the haemodynamic and myocardial effects of propofol-fentanyl anaesthesia in 12 patients undergoing coronary artery bypass surgery during the pre-bypass period. The induction dose of propofol was 1.5 mg kg-1 and mean infusion rate during maintenance was 4.48 mg kg-1 h-1 (range 1.87-7.24 mg kg-1 h-1). Th...

journal_title：British journal of anaesthesia

authors： Vermeyen KM,De Hert SG,Erpels FA,Adriaensen HF

更新日期：1991-04-01 00:00:00

abstract：:One hundred and one patients with osteoarthritis were randomly allocated to undergo total hip arthroplasty under either spinal (subarachnoid) or general anaesthesia. Venous blood was sampled before, during and after surgery and on the 5th day after operation to study the haemostatic mechanism. There were no preoperati...

journal_title：British journal of anaesthesia

authors： Davis FM,McDermott E,Hickton C,Wells E,Heaton DC,Laurenson VG,Gillespie WJ,Foate J

更新日期：1987-05-01 00:00:00

abstract：:A technique of induction of anaesthesia using propanidid, lignocaine and suxamethonium is described, and the muscle fasciculations that follow it are shown to be significantly less than those accompanying induction with methohexitone and suxamethonium. ...

journal_title：British journal of anaesthesia

authors： Fry EN

更新日期：1975-06-01 00:00:00

abstract：:Interest in the use of psychosocial interventions to help older adults manage pain is growing. In this article, we review this approach. The first section reviews the conceptual background for psychosocial interventions with a special emphasis on the biopsychosocial model of pain. The second section highlights three p...

journal_title：British journal of anaesthesia

authors： Keefe FJ,Porter L,Somers T,Shelby R,Wren AV

更新日期：2013-07-01 00:00:00

abstract：:A 4-year-old girl developed severe hepatitis following the fourth administration of halothane in a period of 5 months. She was shown to have a circulating antibody which acted specifically against rabbit hepatocyte previously sensitized to halothane. The patient made a full recovery from the hepatitis, but 5 months la...

journal_title：British journal of anaesthesia

authors： Lewis RB,Blair M

更新日期：1982-03-01 00:00:00

abstract：:This paper describes the use of solenoid valves for the production of binary gas mixtures. The system is controlled by a microprocessor and is capable of delivering accurate flows and concentrations of gases over the ranges commonly used in anaesthesia. Since the flow produced by the valves is pulsatile, a system for ...

journal_title：British journal of anaesthesia

authors： Palayiwa E,Hahn CE,Sugg BR,Lindsay-Scott D,Tyrrell PJ

更新日期：1986-09-01 00:00:00

abstract：:The isolated rat hepatocyte model has been used to assess the hepatotoxicity of a number of i.v. anaesthetic induction agents. Ketamine, Althesin and CCI 12923 (minaxolone) all inhibited gluconeogenesis and urea formation from alanine. There was also a decrease in the cell ATP concentration, and a dose-related increas...

journal_title：British journal of anaesthesia

authors： Sear JW,McGivan JD

更新日期：1979-08-01 00:00:00

abstract：:The haemodynamic responses to isovolumic anaemia (dextran-for-blood exchange) were studied in seven dogs pretreated with propranolol 20 mg/kg body weight for 3 weeks. Adrenergic beta-receptor blockade did not prevent significant increases in heart rate (up to 19%). Cardiac output increased by about 20% while systemic ...

journal_title：British journal of anaesthesia

authors： Clarke TN,Foëx P,Roberts JG,Saner CA,Bennett MJ

更新日期：1980-03-01 00:00:00

abstract：:We have investigated, in six healthy male volunteers, the effect of high thoracic extradural anaesthesia on the ventilatory pattern and hypercapnic ventilatory response. Ventilatory variables were determined using a respiratory inductive plethysmograph. Duration of inspiration, rib cage excursion and its contribution ...

journal_title：British journal of anaesthesia

authors： Kochi T,Sako S,Nishino T,Mizuguchi T

更新日期：1989-04-01 00:00:00

abstract：:In a prospective study, patients undergoing abdominal surgery were allocated randomly to receive intermittent morphine 10 mg i.m. (n = 41) or a single injection of buprenorphine 0.3 mg i.m. followed by sublingual buprenorphine 0.4 mg every 6 h (n = 39) for 3 days following operation. Patients receiving buprenorphine w...

journal_title：British journal of anaesthesia

authors： Cuschieri RJ,Morran CG,McArdle CS

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:There has been a renewed interest in nitric oxide donor drugs, such as nitroglycerin, delivered by the inhalational route for treatment of pulmonary arterial hypertension (PAH). We investigated the acute effects of inhaled nitroglycerin on pulmonary and systemic haemodynamics in children with PAH associated ...

journal_title：British journal of anaesthesia

authors： Goyal P,Kiran U,Chauhan S,Juneja R,Choudhary M

更新日期：2006-08-01 00:00:00

abstract：:This paper reports three investigations of the suggested relationship between sudden infant death syndrome (SIDS) and malignant hyperpyrexia (MH). In the first study 151 MH-susceptible families completed a questionnaire designed to identify the incidence of SIDS within their own pedigree. In the second study 106 SIDS ...

journal_title：British journal of anaesthesia

authors： Ellis FR,Halsall PJ,Harriman DG

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:The effect of anaesthesia on postoperative outcome is unclear. Cardioprotective properties of volatile anaesthetics have been demonstrated experimentally and in haemodynamically stable patients undergoing coronary artery bypass grafting. Their effects in patients undergoing high-risk cardiac surgery have not...

journal_title：British journal of anaesthesia

authors： Landoni G,Guarracino F,Cariello C,Franco A,Baldassarri R,Borghi G,Covello RD,Gerli C,Crivellari M,Zangrillo A

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The perioperative period may be associated with a marked neurohumoral stress response, significant fluid losses, and varied fluid replacement regimes. Acute changes in serum sodium concentration are therefore common, but predictors and outcomes of these changes have not been investigated in a large surgical ...

journal_title：British journal of anaesthesia

authors： Klinck J,McNeill L,Di Angelantonio E,Menon DK

更新日期：2015-04-01 00:00:00

abstract：:Relative humidity of air produced by simple compressors used to drive ventilators was measured at different working pressures. At normal working pressures, a relative humidity of 100% was found and condensation occurred, mainly at the high pressure air/oxygen mixer valve. This resulted in blockages and loss of accurac...

journal_title：British journal of anaesthesia

authors： Conely JI,Railton R,MacKenzie AI

更新日期：1981-05-01 00:00:00

abstract：:Seventy-two adult surgical patients were studied to compare neuromuscular and cardiovascular effects of mivacurium chloride during nitrous oxide-fentanyl-thiopentone (BAL group) or nitrous oxide-halothane (HAL group) anaesthesia. Eighteen patients in the BAL group received an initial bolus of mivacurium, either the ED...

journal_title：British journal of anaesthesia

authors： From RP,Pearson KS,Choi WW,Abou-Donia M,Sokoll MD

更新日期：1990-02-01 00:00:00

abstract：:We conducted a randomized, double-blind comparison of 8% sevoflurane and propofol as induction agents for day-case cystoscopy in 102 patients. All patients received an i.v. cannula and breathed oxygen 5 litre min-1. Anaesthesia was induced with propofol i.v. or inhalation of 8% sevoflurane and 10% Intralipid (as a pla...

journal_title：British journal of anaesthesia

authors： Thwaites A,Edmends S,Smith I

更新日期：1997-04-01 00:00:00

abstract：:We have investigated the effect of volatile anaesthetics on protein synthesis and secretion in Hartley male guinea pig liver slices. The slices (250-300 microns thick) were incubated in sealed roller vials containing Krebs-Henseleit buffer at 37 degrees C under 95% oxygen. Volatile anaesthetics were vaporized in the v...

journal_title：British journal of anaesthesia

authors： Ghantous HN,Fernando JL,Keith RL,Gandolfi AJ,Brendel K

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Intravenous amino acid infusion during general anaesthesia prevents decreases in core temperature resulting from increased energy expenditure and heat accumulation. METHODS:We investigated whether such stimulation also occurs during spinal anaesthesia, which blocks sympathetic nervous activity. We examined ...

journal_title：British journal of anaesthesia

authors： Kasai T,Nakajima Y,Matsukawa T,Ueno H,Sunaguchi M,Mizobe T

更新日期：2003-01-01 00:00:00

abstract：:We have measured the onset and extent of the miotic effect of morphine and alfentanil in conscious patients. Forty unpremedicated ASA I and II patients were allocated randomly to four groups to receive either i.v. saline (control group), morphine 0.1 mg kg-1, alfentanil 4.0 micrograms kg-1 or a combination of these do...

journal_title：British journal of anaesthesia

authors： Miller CD,Asbury AJ,Brown JH

更新日期：1990-09-01 00:00:00

abstract：:We have measured the n-octanol/water distribution coefficients at 37 degrees C of two steroidal myoneural blockers (pancuronium and vecuronium) and of their 3-hydroxy metabolites over a pH range from 1.5 to 11. Pancuronium was found not to be lipid soluble. The mean distribution coefficient of 3-hydroxy vecuronium at ...

journal_title：British journal of anaesthesia

authors： Weindlamayr-Goettel M,Gilley H,Sipos E,Steinbereithner K

更新日期：1993-05-01 00:00:00

abstract：:A possible means of rapid cooling in the emergency treatment of malignant hyperpyrexia, peritoneal dialysis using a cold dialysate, is described. Experimental observations in a young man on a regular peritoneal dialysis regime showed that significant heat extraction can be obtained when either a cool (20 degrees C) or...

journal_title：British journal of anaesthesia

authors： Gjessing J,Barsa J,Tomlin PJ

更新日期：1976-05-01 00:00:00

abstract：:To assess the effect of sevoflurane anaesthesia on hepatocellular integrity, we measured plasma concentrations of glutathione S-transferase (GST) before anaesthesia and 1, 3, 6 and 24 h after the end of anaesthesia in 41 healthy, Japanese patients undergoing elective, body surface surgery. Sevoflurane (approximately 1...

journal_title：British journal of anaesthesia

authors： Ray DC,Bomont R,Mizushima A,Kugimiya T,Forbes Howie A,Beckett GJ

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Multiple cognitive and psychiatric disorders are associated with an increased tonic inhibitory conductance that is generated by α5 subunit-containing γ-aminobutyric acid type A (α5 GABAA) receptors. Negative allosteric modulators that inhibit α5 GABAA receptors (α5-NAMs) are being developed as treatments for...

journal_title：British journal of anaesthesia

authors： Manzo MA,Wang DS,Li WW,Pinguelo A,Popa MO,Khodaei S,Atack JR,Ross RA,Orser BA

更新日期：2020-12-30 00:00:00

abstract：:We have evaluated the effect of delivering nitric oxide using a continuous flow system (CFS) or two commercially available proportional gas injection systems (PGIS), Nodomo (Dräger, Lübeck, Germany) and Pulmonox-Mini (Messer Griesheim Austria, Gumpoldskirchen, Austria) on measured and simulated concentrations of nitri...

journal_title：British journal of anaesthesia

authors： Hiesmayr MJ,Neugebauer T,Lassnigg A,Steltzer H,Haider W,Gilly H

更新日期：1998-10-01 00:00:00

abstract：:We determined in 51 healthy patients undergoing body surface surgery the dose requirements for propofol, as part of a total i.v. anaesthesia technique with an alfentanil infusion. After premedication with temazepam, patients received alfentanil 50 micrograms kg-1 followed by an infusion of 50 micrograms kg-1 h-1. Pati...

journal_title：British journal of anaesthesia

authors： Richards MJ,Skues MA,Jarvis AP,Prys-Roberts C

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:Cardiac surgery with cardiopulmonary bypass (CPB) is commonly perceived as a risk factor for decline in renal function, especially in patients with preoperative renal dysfunction. There are few data on the effects of CPB on renal function in patients with mild preoperative renal dysfunction. The purpose of t...

journal_title：British journal of anaesthesia

authors： Loef BG,Henning RH,Navis G,Rankin AJ,van Oeveren W,Ebels T,Epema AH

更新日期：2008-06-01 00:00:00