Lower oesophageal contractility and detection of awareness during anaesthesia.

Abstract:

:We have investigated the value of lower oesophageal contractility (LOC) in detecting awareness during anaesthesia in 20 human volunteer patients. LOC was measured either with subjects awake or after induction with propofol, during induction with propofol, and then as consciousness returned. Statistically significant changes were observed in the frequency of spontaneous contractions, peak and mean amplitude of spontaneous and provoked contractions, and the oesophageal contractility index as subjects lost consciousness and also as it was regained. The differences in LOC which occurred when subjects were conscious and unconscious support the view that LOC is related to the depth of anaesthesia, but its unreliability at the interface between consciousness and unconsciousness prevents selective detection of awareness, although the response in the presence of painful stimuli has not been tested.

journal_name

Br J Anaesth

authors

Isaac PA,Rosen M

doi

10.1093/bja/65.3.319

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

319-24

issue

3

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)48387-5

journal_volume

65

pub_type

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