Abstract:
:Chlorhexidine allergy has been described in the literature, mainly in Japanese individuals. Most reactions have been limited to the skin, mild in severity and a result of chlorhexidine containing solutions such as 'Savlon' (Novartis Consumer Health, Horesham, UK). We describe what we believe is the first reported case of anaphylaxis in a European patient to a chlorhexidine- sulphadiazine-coated central venous catheter.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Stephens R,Mythen M,Kallis P,Davies DW,Egner W,Rickards Adoi
10.1093/bja/87.2.306subject
Has Abstractpub_date
2001-08-01 00:00:00pages
306-8issue
2eissn
0007-0912issn
1471-6771pii
S0007-0912(17)37643-2journal_volume
87pub_type
杂志文章abstract:Background:Blood lactate is a strong predictor of mortality, and repeated blood lactate assays are recommended during surgery in high-risk patients. We hypothesized that the use of intravascular microdialysis incorporated in a central venous catheter would be interchangeable with the reference blood gas technique to mo...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aex338
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:Recent investigations showed that isoflurane can induce pharmacological preconditioning. The present study aimed to compare the potency of four different halogenated anaesthetics to induce preconditioning. METHODS:Anaesthetized open-chest rabbits underwent 30 min of coronary artery occlusion followed by 3 h...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:The ability of the third-generation FloTrac/Vigileo software to track changes in cardiac index (CI) induced by volume expansion and norepinephrine in critically ill patients is unknown. METHODS:In subjects with circulatory failure, we administered volume expansion (20 subjects) and increased (20 subjects) o...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aer491
更新日期:2012-04-01 00:00:00
abstract::We have studied the effects of alcuronium in 10 healthy, non-anaesthetized volunteers after they had been taking oral pyridostigmine 30 mg 8 hourly. The responses of adductor pollicis were recorded using an isolated forearm procedure (IFP) during onset and recovery of neuromuscular block produced by 1.5 mg of relaxant...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/66.3.365
更新日期:1991-03-01 00:00:00
abstract:BACKGROUND:Better education of clinicians is expected to enhance patient safety. An important component of education is adherence to standard protocols, which are mainly available in written form. Believing in the potential power of videos, we hypothesized that the introduction of an educational video, based on an inst...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aew030
更新日期:2016-05-01 00:00:00
abstract::Cancer survivorship represents a growing clinical challenge for pain clinicians. The population of cancer survivors is rapidly expanding and many of these patients experience pain as a sequelae of their disease and its treatment. The features, pathophysiology and natural history of some painful conditions observed in ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,评审
doi:10.1093/bja/aex202
更新日期:2017-10-01 00:00:00
abstract:Background:. Missense variants in the ryanodine receptor 1 gene ( RYR1 ) are associated with malignant hyperthermia but only a minority of these have met the criteria for use in predictive DNA diagnosis. We examined the utility of a simplified method of segregation analysis and a functional assay for determining the pa...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aex042
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Left ventricular (LV) pressure-volume (PV) loops were used to compare the functional effects that accompany the cardioprotection seen with desflurane, sevoflurane, and propofol in a rabbit preparation of coronary ischaemia-reperfusion (IR). METHODS:Male New Zealand White rabbits (n=48) were anaesthetized wi...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aep238
更新日期:2009-11-01 00:00:00
abstract::Resperatory compliance and resistance were measured during positive pressure ventilation in anaesthtized, paralysed dogs. Airway pressures measured during constant-flow inspiration allowed the calculation of pulmonary and chest-wall resistances, and static and non-static compliances. Contiguous studies of dynamic comp...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/48.12.1157
更新日期:1976-12-01 00:00:00
abstract:BACKGROUND:Assessments of labour pain focus on pain intensity, not on duration. We aimed to assess the importance labouring women apply to pain intensity and duration before labour and post-delivery. METHODS:Forty healthy women scheduled for labour induction were enrolled in this institutional review board-approved, p...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aeu149
更新日期:2014-09-01 00:00:00
abstract::Abnormal oxygen use and organ failure in the critically ill may result from 'poisoning' of mitochondrial function. Measurement of arterial ketone body ratio (AKBR) has been proposed to reflect mitochondrial redox state and may provide a useful marker to monitor mitochondrial function in the critically ill. We measured...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/83.2.325
更新日期:1999-08-01 00:00:00
abstract:Background:Identification of statistically reliable outcomes for comparison among anaesthetists is challenging. Time-weighted intraoperative mean arterial pressure <65 mm Hg (AUC 65 ) is associated with increased odds for myocardial damage. We explored retrospectively whether such hypotension before incision was statis...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aex153
更新日期:2017-07-01 00:00:00
abstract::Intrathecal midazolam causes antinociception by combining with spinal cord benzodiazepine receptors. This effect is reversible with doses of naloxone, suggesting involvement of spinal kappa or delta but not mu opioid receptors. The antinociceptive effects of intrathecally administered drugs in the spinal cord were dem...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/77.6.758
更新日期:1996-12-01 00:00:00
abstract::We have measured in 38 patients the plasma concentration profile of atracurium and its effect on the electromyographic first response of the train-of-four. One of three techniques was used to supplement anaesthesia with 66% nitrous oxide in oxygen, 0.9% isoflurane (end-tidal), 0.5% halothane (end-tidal) or midazolam 3...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1093/bja/70.1.38
更新日期:1993-01-01 00:00:00
abstract::We studied the pharmacokinetics of glycopyrronium in 11 uraemic patients undergoing cadaveric renal transplantation and in seven ASA I control patients undergoing general surgery. Glycopyrronium 4 micrograms kg-1 was given i.v. before induction of anaesthesia. Blood and urine samples were collected for up to 24 h for ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/71.3.437
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:Axillary vein catheterization via a distal approach is an alternative to the proximal approach to axillary/subclavian vein catheterization under ultrasound (US) guidance. The aim of this trial was to compare the two approaches. METHODS:In a randomized single-centre study, all patients requiring central vein...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1093/bja/aev458
更新日期:2016-02-01 00:00:00
abstract::The effect of ketamine analgesia on gastric emptying was assessed in five healthy volunteers. Gastric emptying, estimated indirectly by the absorption of orally administered paracetamol, was not significantly delayed following administration of i.m. ketamine when compared with placebo. ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/53.12.1321
更新日期:1981-12-01 00:00:00
abstract::The effects of ventilation with 30% and 100% oxygen were investigated on the circulatory and electrocardiographic response to electroconvulsive therapy (ECT) in 12 patients during 40 treatments. Administration of 30% oxygen resulted in a 25% decrease in seizure duration compared with 100% oxygen (P less than 0.0125). ...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/61.5.593
更新日期:1988-11-01 00:00:00
abstract::We have studied haemodynamic responses to 0, 0.25, 0.5, 0.75 and 1 MAC isoflurane administration in 10 patients during a zero-order propofol infusion and normocapnia. Isoflurane reduced mean arterial pressure (MAP), systemic vascular resistance and left ventricular stroke work in a dose-dependent manner (29%, 38% and ...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/69.1.36
更新日期:1992-07-01 00:00:00
abstract::We report a case of improved cardiopulmonary exercise (CPX) test outcomes measured 48 h after initial CPX testing and immediately after alterations were made to the settings of a dual chamber, dual sensing pacemaker with exercise detection. The changes allowed successful abdominal surgery to be completed. ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/aet587
更新日期:2014-06-01 00:00:00
abstract::We have studied the tone of the lower oesophageal sphincter (LOS) in 40 adults undergoing routine body surface surgery and allocated randomly to receive anaesthesia either by face mask and Guedel airway or by laryngeal mask airway. In the laryngeal mask group there was a mean (SEM) decrease in barrier pressure (LOS mi...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/69.4.346
更新日期:1992-10-01 00:00:00
abstract::Loss of resistance dorsal to the ligamentum flavum was recorded in 10 of 16 patients aged 43--75 yr whilst performing extradural anaesthesia at the L2--3 interspace via the midline approach. Degeneration of the interspinous ligament with cavity formation is observed frequently in the elderly and may account for false ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/51.3.253
更新日期:1979-03-01 00:00:00
abstract::Using cats with chronically implanted brain electrodes, we have compared the effects of propofol on CNS electrical activities with those of thiopentone. Ten cats were allocated to receive either propofol (n = 5) or thiopentone (n = 5). Cats were anaesthetized initially with 4% halothane in oxygen. The trachea was intu...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/71.3.383
更新日期:1993-09-01 00:00:00
abstract::We have assessed tracheal intubating conditions in 60 ASA I or II patients after induction of anaesthesia with propofol 2.5 mg kg-1 and alfentanil 10 or 20 micrograms kg-1 with or without i.v. lignocaine 1 mg kg-1. No neuromuscular blocking agents were administered. Patients were allocated randomly to four groups: gro...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1093/bja/70.2.163
更新日期:1993-02-01 00:00:00
abstract::We studied the interactive effect of dexmedetomidine and morphine on gastric emptying and gastrointestinal transit in the rat. In one group of rats, to examine the interactive effect on gastrointestinal transit, the two drugs were injected i.p. in a fixed ratio (30: 1)--that of their ED50 values--in six doses (0.062-1...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/80.1.63
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Clinicians frequently warn patients of discomfort before potentially painful procedures, despite the lack of evidence that such communications are helpful. We aimed to compare two communications (one with, and the other without, a warning of a 'sting') immediately before i.v. cannulation in order to measure ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1093/bja/aem308
更新日期:2007-12-01 00:00:00
abstract::A patient with a tracheostomy and an iatrogenic tracheo-oesophageal fistula presented for diagnostic bronchoscopy and right upper lobectomy. The anaesthetic management is discussed with reference to the options available and, in particular, the use of a Brompton Pallister single lumen endobronchial tube. ...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/74.4.461
更新日期:1995-04-01 00:00:00
abstract::This review describes the laboratory evidence and microvascular mechanisms responsible for the beneficial effects of statins in sepsis. During sepsis, changes occur within the microcirculation including alterations in arteriolar tone influencing blood pressure, adaptations to endothelial cell integrity causing leakage...
journal_title:British journal of anaesthesia
pub_type: 杂志文章,评审
doi:10.1093/bja/ael358
更新日期:2007-02-01 00:00:00
abstract::Bispectral index (BIS) was assessed as a monitor of depth of anaesthesia during fentanyl and midazolam anaesthesia for coronary bypass surgery. In 10 patients given morphine premedication, anaesthesia was induced with a combination of midazolam and fentanyl and thereafter maintained with a continuous infusion of a mix...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1093/oxfordjournals.bja.a013587
更新日期:2000-06-01 00:00:00
abstract::Changes in intragastric pressure after the administration of suxamethonium 1.5 mg kg-1 i.v. were studied in 32 children (mean age 6.9 yr) pretreated with either physiological saline or alfentanil 50 micrograms kg-1. Anaesthesia was induced with thiopentone 5 mg kg-1. The incidence and intensity of muscle fasciculation...
journal_title:British journal of anaesthesia
pub_type: 杂志文章
doi:10.1093/bja/60.2.176
更新日期:1988-02-01 00:00:00