Pain in cancer survivors; filling in the gaps.

Abstract:

:Cancer survivorship represents a growing clinical challenge for pain clinicians. The population of cancer survivors is rapidly expanding and many of these patients experience pain as a sequelae of their disease and its treatment. The features, pathophysiology and natural history of some painful conditions observed in cancer survivors, such as direct tumour effects, cancer induced bone pain (CIBP) or chronic post-surgical pain have received extensive exposure elsewhere in the literature. In this narrative review, we attempt to 'fill in the gaps' in the knowledge, by providing a succinct outline of a range of less well known pain states encountered in the cancer survivor population. These include neuropathies as a result of graft versus host disease (GVHD), novel chemotherapeutic agents and monoclonal antibodies (mAb), and radiation induced pain states. The increasing prevalence of visceral post-surgical pain and aromatase inhibitor-induced arthralgia (AIA) is also detailed. Additionally an overview of suggested approaches to the assessment of pain in cancer survivors is provided and potential treatment strategies, with a focus on novel approaches are discussed.

journal_name

Br J Anaesth

authors

Brown M,Farquhar-Smith P

doi

10.1093/bja/aex202

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

723-736

issue

4

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)53815-5

journal_volume

119

pub_type

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