Comparison of the incidence and nature of cardiac arrhythmias occurring during isoflurane or halothane anaesthesia. Studies during dental surgery.

abstract：:We report the extradural administration of low-dose morphine in 10 ml of 10% dextrose (2-3 mg) to 98 adult patients with various types of acute and chronic pain. Extradural morphine injections were given either via a Tuohy needle (single or repeat injection) or via an extradural catheter. Pain relief was evaluated by ...

journal_title：British journal of anaesthesia

authors： Magora F,Olshwang D,Eimerl D,Shorr J,Katzenelson R,Cotev S,Davidson JT

更新日期：1980-03-01 00:00:00

abstract：:As the route of breathing and use of airway apparatus such as mask, mouthpiece and noseclip can alter breathing pattern, this study has used the helium dilution method to estimate the effects of mouthpiece and mask breathing on functional residual capacity (FRC) in the supine position, and the change in FRC that occur...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1996-04-01 00:00:00

abstract：:A simple mathematical model of the chest wall was constructed so that during tidal breathing the relative volume contributions of the rib cage and abdomen/diaphragm could be measured in man, using four mercury-in-rubber strain gauges around the trunk. From the dimensions of the trunk and the change in circumference de...

journal_title：British journal of anaesthesia

authors： Faithfull D,Jones JG,Jordan C

更新日期：1979-05-01 00:00:00

abstract：:The analgesic efficacy of a 150-mg meptazinol suppository was compared with that of morphine 10 mg i.m. in the treatment of moderate postoperative pain. Two groups of 15 female patients took part in a 4-h, randomized double-blind, double-dummy study on the first day after elective abdominal hysterectomy. Meptazinol di...

journal_title：British journal of anaesthesia

authors： Moores MA,Frater R,Parry P,Hanning CD

更新日期：1988-04-01 00:00:00

abstract：:Since the preoperative administration of water might promote gastric emptying and dilute the remaining gastric contents, 50 patients were investigated before elective surgery. One group was given water 100 ml 2 h before operation; the other group was fasted as usual. Volume and pH of gastric contents were measured imm...

journal_title：British journal of anaesthesia

authors： McGrady EM,Macdonald AG

更新日期：1988-06-01 00:00:00

abstract：:The new emulsion formulation of di-isopropyl phenol (propofol) was compared with methohexitone and thiopentone for induction of anaesthesia in day cases. Propofol produced significantly smoother induction of anaesthesia, but caused more cardiovascular and respiratory depression. Pain on injection was significantly les...

journal_title：British journal of anaesthesia

authors： Mackenzie N,Grant IS

更新日期：1985-08-01 00:00:00

abstract：:All 484 candidates for the 1988 Fellowship in Anaesthesia (Part Three) were surveyed to investigate any differences between successful and unsuccessful candidates in study techniques, work and domestic factors, and examination history that might lead to better guidance to those preparing for the examination and an imp...

journal_title：British journal of anaesthesia

authors： David AC,Elton RA,Spence AA,Hatch DJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Fast onset and short duration are prominent properties of the amide-type local anaesthetic articaine. Similar to bupivacaine, a hyperbaric solution of articaine may produce faster onset and shorter duration of spinal anaesthesia than a plain solution. METHODS:Patients undergoing open inguinal hernia repair ...

journal_title：British journal of anaesthesia

authors： Bachmann M,Pere P,Kairaluoma P,Rosenberg PH,Kallio H

更新日期：2008-12-01 00:00:00

abstract：:Nociceptin/orphanin FQ, N/OFQ, and its receptor NOP represent a non-opioid branch of the opioid superfamily that were first studied for their effects on pain responses. Both N/OFQ and NOP are involved in a wide range of 'non-pain' responses including immunomodulation and cardiovascular control. There is now growing in...

journal_title：British journal of anaesthesia

authors： Serrano-Gomez A,Thompson JP,Lambert DG

更新日期：2011-01-01 00:00:00

abstract：:The isolated rat hepatocyte model has been used to assess the hepatotoxicity of a number of i.v. anaesthetic induction agents. Ketamine, Althesin and CCI 12923 (minaxolone) all inhibited gluconeogenesis and urea formation from alanine. There was also a decrease in the cell ATP concentration, and a dose-related increas...

journal_title：British journal of anaesthesia

authors： Sear JW,McGivan JD

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:During normothermic cardiopulmonary bypass (CPB), the effect on propofol pharmacokinetics of changes in its binding to plasma proteins is consistent with the predictions of the well-stirred model of hepatic elimination for nonrestrictively cleared drug. However, whether changes in binding lead to clinically ...

journal_title：British journal of anaesthesia

authors： Takizawa E,Hiraoka H,Takizawa D,Goto F

更新日期：2006-02-01 00:00:00

abstract：Background:Retrospective clinical studies suggest there is a risk for neurodevelopmental impairment following early childhood exposure to anaesthesia. In the developing animal brain, including those of non-human primates (NHPs), anaesthetics induce apoptotic cell death. We previously reported that a 5 h isoflurane (ISO...

journal_title：British journal of anaesthesia

authors： Noguchi KK,Johnson SA,Dissen GA,Martin LD,Manzella FM,Schenning KJ,Olney JW,Brambrink AM

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:As general anaesthesia may compromise the immune system, it has been hypothesized that latent varicella-zoster virus is more likely to be reactivated and cause herpes zoster in mothers after Caesarean deliveries under general anaesthesia. Our study was thus aimed at investigating the risk of herpes zoster am...

journal_title：British journal of anaesthesia

authors： Chen YH,Rau RH,Keller JJ,Lin HC

更新日期：2012-02-01 00:00:00

abstract：:The effects of diazepam, which acts at GABAA receptors to enhance the effects of GABA, and ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, on local rates of cerebral glucose utilization (ICMRglc) were examined in unrestrained rats. Four groups were studied: vehicle-injected controls; and ketamine...

journal_title：British journal of anaesthesia

authors： Eintrei C,Sokoloff L,Smith CB

更新日期：1999-04-01 00:00:00

abstract：:Three anaesthetic techniques based on isoflurane were compared in outpatients undergoing laparoscopy. Sixty healthy patients were randomly allocated to receive isoflurane via mask (spontaneous respiration), via tracheal tube (spontaneous respiration) or via tracheal tube with controlled ventilation. Moderate hypercarb...

journal_title：British journal of anaesthesia

authors： Kenefick JP,Leader A,Maltby JR,Taylor PJ

更新日期：1987-02-01 00:00:00

abstract：:Human plasma cholinesterase (E.C. 3.1.1.8) was shown to be inhibited by physiological concentrations of propanidid and suxamethonium using a colourimetric assay at 25 degrees C and pH 7.2 unit with butyrylthiocholine as substrate. Propanidid inhibited the enzyme in a non-competitive manner (I50 = 2.0 mmol litre-1; app...

journal_title：British journal of anaesthesia

authors： Taussig PE,Stojak HE,Bennett NR

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:Ketamine is widely used as an i.v. anaesthetic agent and as a drug of abuse. Hepatocytes contribute to the metabolism of endogenous and exogenous substances. This study evaluated the toxic effects of S-(+)-ketamine and possible mechanisms using human hepatoma HepG2 cells as the experimental model. METHODS:H...

journal_title：British journal of anaesthesia

authors： Lee ST,Wu TT,Yu PY,Chen RM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Perioperative warming is recommended for surgery under anaesthesia, however its role during Caesarean delivery remains unclear. This meta-analysis aimed to determine the efficacy of active warming on outcomes after elective Caesarean delivery. METHODS:We searched databases for randomized controlled trials u...

journal_title：British journal of anaesthesia

authors： Sultan P,Habib AS,Cho Y,Carvalho B

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Anaesthesia and surgery are associated with impairment of the immune system expressed as an excessive proinflammatory immune response and suppression of cell-mediated immunity that may affect the course of the postoperative period. Addition of anaesthetic agents capable of attenuating the alterations in peri...

journal_title：British journal of anaesthesia

authors： Beilin B,Rusabrov Y,Shapira Y,Roytblat L,Greemberg L,Yardeni IZ,Bessler H

更新日期：2007-10-01 00:00:00

abstract：:We have assessed the role of the cell-cell adhesion molecule, E-cadherin, in the pathogenesis of multiorgan failure in 24 intensive care patients with sepsis and varying degrees of organ dysfunction, compared with 21 healthy subjects. Plasma soluble E-cadherin (sE-cadherin) was measured by enzyme immunoassay. The medi...

journal_title：British journal of anaesthesia

authors： Pittard AJ,Banks RE,Galley HF,Webster NR

更新日期：1996-05-01 00:00:00

abstract：:A method for the assessment and management of factors both causing and maintaining a primary metabolic alkalosis is presented. During a 2-year period 65 patients with metabolic alkalosis were treated with saline and potassium chloride infusions. In four patients the alkalosis was refractory and required additional the...

journal_title：British journal of anaesthesia

authors： Worthley LI

更新日期：1977-08-01 00:00:00

abstract：:A variant of a rebreathing/indicator-dilution technique was used to measure lung volume. Two or three indicators, which should have essentially the same pulmonary volume of distribution, were used. Gas compositions were measured by respiratory mass spectrometry and an extrapolation was used to allow for oxygen consump...

journal_title：British journal of anaesthesia

authors： Black AM,Hahn CE,Maynard P,Scott IL

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Ketamine-induced neuroapoptosis has been attributed to diverse stress-related mechanisms. Glycogen synthase kinase-3β (GSK-3β) is a multifunctional kinase that is active in neuronal development and linked to neurodegenerative disorders. We hypothesized that ketamine would enhance GSK-3β-induced neuroapopotos...

journal_title：British journal of anaesthesia

authors： Liu JR,Baek C,Han XH,Shoureshi P,Soriano SG

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:LMA CTrach (CT), a modified version of the intubating LMA Fastrach, allows continuous video-endoscopy of the tracheal intubation procedure. We tested the hypothesis that the CT is efficient for tracheal intubation of morbidly obese patients who are at risk of a difficult airway. METHODS:After Ethics' Commit...

journal_title：British journal of anaesthesia

authors： Dhonneur G,Ndoko SK,Yavchitz A,Foucrier A,Fessenmeyer C,Pollian C,Combes X,Tual L

更新日期：2006-11-01 00:00:00

abstract：:MHS and normal pigs were anaesthetized with nitrous oxide and diazepam. Halothane 1% was then administered for 1 hr. Immediately before and immediately after the halothane inhalation, 10 g of vastus lateralis muscle was excised. SR was isolated from this muscle. Calcium accumulation by the MHS sarcoplasmic reticulum i...

journal_title：British journal of anaesthesia

authors： Britt BA,Endrenyi L,Cadman DL

更新日期：1975-06-01 00:00:00

abstract：:The kinetics of morphine were studied during balanced anaesthesia in 10 patients undergoing lower abdominal or body surface surgery, and compared with those obtained in nine awake patients receiving morphine i.v. for the relief of chronic non-cancer pain. All patients received morphine sulfphate pentahydrate 10 mg i.v...

journal_title：British journal of anaesthesia

authors： Sear JW,Hand CW,Moore RA,McQuay HJ

更新日期：1989-01-01 00:00:00

abstract：:Robotic surgery pushes the frontiers of innovation in healthcare technology towards improved clinical outcomes. We discuss the evolution to five generations of robotic surgical platforms including stereotactic, endoscopic, bioinspired, microbots on the millimetre scale, and the future development of autonomous systems...

journal_title：British journal of anaesthesia

authors： Ashrafian H,Clancy O,Grover V,Darzi A

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Several medications have proved to be useful in preventing postoperative nausea and vomiting (PONV). However, routine antiemetic prophylaxis is not cost-effective. We evaluated the accuracy and discriminating power of an artificial neural network (ANN) to predict PONV. METHODS:We analysed data from 1086 in-...

journal_title：British journal of anaesthesia

authors： Peng SY,Wu KC,Wang JJ,Chuang JH,Peng SK,Lai YH

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:The aim of this study is to test the hypothesis that a standard 30-min break in a routine 7.5 h period of work makes a difference in cognitive function. METHODS:In a double-blinded, cross-over trial 30 residents in anaesthesia were randomized to receive or not to receive a 30-min break between the assessmen...

journal_title：British journal of anaesthesia

authors： Coburn M,Henzler D,Baumert JH,Fimm B,Drüke B,Rossaint R

更新日期：2006-09-01 00:00:00

abstract：:One explanation for diminished opioid analgesic efficacy is opioid-induced hyperalgesia (OIH). We report a case of OIH in an infant with gastroschisis, requiring multiple surgical interventions and prolonged sedation for ventilation. This is the first report of OIH in an infant. On day 41 of life after nine separate s...

journal_title：British journal of anaesthesia

authors： Hallett BR,Chalkiadis GA

更新日期：2012-01-01 00:00:00