A multicentre comparison of the costs of anaesthesia with sevoflurane or propofol.

abstract：:We have compared the effects of sevoflurane and halothane on the discharge frequencies of 19 slowly adapting and four rapidly adapting lung receptors in the rabbit by recording from single vagal fibres. Both agents reduced the discharge frequency of slowly adapting receptors during expiration (P < 0.0005), halothane h...

journal_title：British journal of anaesthesia

authors： Moores C,Davies AS,Dallak M

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Better education of clinicians is expected to enhance patient safety. An important component of education is adherence to standard protocols, which are mainly available in written form. Believing in the potential power of videos, we hypothesized that the introduction of an educational video, based on an inst...

journal_title：British journal of anaesthesia

authors： Kandler L,Tscholl DW,Kolbe M,Seifert B,Spahn DR,Noethiger CB

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Arterial cannulation is a common anaesthetic procedure that can be challenging and time-consuming in small children. By visualizing the position of the radial artery, near-infrared vascular imaging systems (NIRVISs) might be of assistance in arterial cannulation. The present study evaluates the effectiveness...

journal_title：British journal of anaesthesia

authors： Cuper NJ,de Graaff JC,Hartman BJ,Verdaasdonk RM,Kalkman CJ

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Hydroxyethyl starch (HES) may affect blood coagulation. We studied the effects of a modified, balanced, high-molecular weight [mean molecular weight (MW) 550 kDa], high-substituted [degree of substitution (DS) 0.7] HES preparation (Hextend) on coagulation in patients undergoing major abdominal surgery. METH...

journal_title：British journal of anaesthesia

authors： Boldt J,Haisch G,Suttner S,Kumle B,Schellhaass A

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Target-controlled infusion (TCI) systems use pharmacokinetic (PK) models to predict the drug infusion rates necessary to achieve a desired target plasma or effect-site concentration. As new PK models are developed and implemented in TCI systems, there can be uncertainty as to which target concentrations are ...

journal_title：British journal of anaesthesia

authors： Eleveld DJ,Colin P,Absalom AR,Struys MMRF

更新日期：2020-10-01 00:00:00

abstract：:Experiments were performed on 14 anaesthetized, artifically ventilated dogs, in which efferent activity in the phrenic nerve was recorded and blood-gas tensions, arterial pH and core temperature were controlled. Doses of midazolam between 0.2 mg kg-1 and 2 mg kg-1 abolished phrenic nerve activity for periods between 3...

journal_title：British journal of anaesthesia

authors： Gordon G,Grundy EM,Al-Khudhairi D,Anderson DJ,Whitwam JG

更新日期：1984-10-01 00:00:00

abstract：:Intra-oral masses in neonates can seriously compromise the airway, potentially causing hypoxia and death if not recognized and managed appropriately. We report a case in which an intra-oral mass was diagnosed on antenatal ultrasound scan. Preparation for delivery involved a multidisciplinary team approach, with a stra...

journal_title：British journal of anaesthesia

authors： Skelton VA,Goodwin A

更新日期：1999-12-01 00:00:00

abstract：:We have studied 13 patients with diabetic nephropathy and 13 patients with uraemia of other origin undergoing renal transplantation, and 12 control patients undergoing general surgery. QTc dispersion and maximum QTc interval were calculated from the 12-lead ECG, and cardiovascular autonomic function tests were perform...

journal_title：British journal of anaesthesia

authors： Kirvelä M,Yli-Hankala A,Lindgren L

更新日期：1994-12-01 00:00:00

abstract：:Percutaneous dilatational tracheostomy (PDT) is associated with a number of life-threatening complications. We present a case of massive and fatal arterial haemorrhage that occurred in the intensive care unit during an elective PDT on an 86-year-old woman following earlier evacuation of a traumatic subdural haematoma....

journal_title：British journal of anaesthesia

authors： Shlugman D,Satya-Krishna R,Loh L

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Plethysmographic variability index (PVI) is an accurate predictor of fluid responsiveness in mechanically ventilated patients. However, the site of measurement of the plethysmographic waveform impacts its morphology and its respiratory variation. The goal of this study was to investigate the ability of PVI t...

journal_title：British journal of anaesthesia

authors： Desgranges FP,Desebbe O,Ghazouani A,Gilbert K,Keller G,Chiari P,Robin J,Bastien O,Lehot JJ,Cannesson M

更新日期：2011-09-01 00:00:00

abstract：:Regional haemodynamic control by the cardiovascular baroreceptors was examined in dogs anaesthetized with 1 + MAC halothane in oxygen (1%). The open-loop relationships between carotid sinus pressure (CSP) and regional haemodynamics in the iliac, renal, mesenteric, aortic and coeliac beds were examined before vagotomy,...

journal_title：British journal of anaesthesia

authors： Bagshaw RJ,Cox RH

更新日期：1977-06-01 00:00:00

abstract：:The haemodynamic responses to isovolumic anaemia (dextran-for-blood exchange) were studied in seven dogs pretreated with propranolol 20 mg/kg body weight for 3 weeks. Adrenergic beta-receptor blockade did not prevent significant increases in heart rate (up to 19%). Cardiac output increased by about 20% while systemic ...

journal_title：British journal of anaesthesia

authors： Clarke TN,Foëx P,Roberts JG,Saner CA,Bennett MJ

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Patient dissatisfaction has been previously associated with motor block in shoulder surgery patients receiving brachial plexus block. For elective minor wrist and hand surgery, we tested whether a regional block accelerating the early return of upper extremity motor function would improve patient satisfactio...

journal_title：British journal of anaesthesia

authors： Fredrickson MJ,Wolstencroft PJ,Chinchanwala S,Boland MR

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The ProSeal laryngeal mask airway (PLMA) is a new laryngeal mask device with a modified cuff and a drainage tube. METHODS:We assessed the PLMA in 300 anaesthetized adults either paralysed or breathing spontaneously. We assessed insertion characteristics, airway seal pressures, haemodynamic response to inser...

journal_title：British journal of anaesthesia

authors： Evans NR,Gardner SV,James MF,King JA,Roux P,Bennett P,Nattrass R,Llewellyn R,Visu D

更新日期：2002-04-01 00:00:00

abstract：:Several risk scores have been developed to calculate the probability of postoperative nausea and vomiting (PONV). However, the power to discriminate which individual will suffer from PONV is still limited. Thus, we wondered how the number of predictors in a score affects the discriminating power and how the characteri...

journal_title：British journal of anaesthesia

authors： Apfel CC,Kranke P,Greim CA,Roewer N

更新日期：2001-06-01 00:00:00

abstract：:The experimental effort that has been expended in investigating the effects of general anaesthetics on LGICs has been enormous over the past decade. Members of all three LGIC superfamilies have been examined using electrophysiological techniques. Anaesthetics that have been examined include volatile anaesthetics, gase...

journal_title：British journal of anaesthesia

authors： Dilger JP

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:As 6% hydroxyethyl starch (HES) 130/0.40 or 130/0.42 can originate from different vegetable sources, they might have different clinical effects. The purpose of this prospective, randomized, double-blind controlled trial was to compare two balanced tetrastarch solutions, one maize-derived and one potato-deriv...

journal_title：British journal of anaesthesia

authors： Joosten A,Tircoveanu R,Arend S,Wauthy P,Gottignies P,Van der Linden P

更新日期：2016-10-01 00:00:00

abstract：:Protein kinase C (PKC) is a key regulatory enzyme that has been implicated as a molecular target for the action of general anaesthetics. We have determined the effects of halothane on the translocation and down-regulation of conventional PKC (cPKC) by analysing the subcellular distribution of PKC activity, [3H]phorbol...

journal_title：British journal of anaesthesia

authors： Hemmings HC Jr,Adamo AI

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Miller laryngoscope blades are preferred for laryngoscopy in infants and children <2 yr of age. Despite their long history, the laryngeal view with the Miller blade size 1 has never been compared with that with the Macintosh (MAC) blade in children. This prospective, single-blinded, randomized study was desi...

journal_title：British journal of anaesthesia

authors： Passi Y,Sathyamoorthy M,Lerman J,Heard C,Marino M

更新日期：2014-11-01 00:00:00

abstract：:Cancer treatment is associated with significant morbidity and mortality. Surgery is a mainstay of treatment for many tumours, and anaesthetists care for cancer patients on a daily basis. Surgery itself induces a stress response and inhibits the immune system, and cancer surgery is associated with the release of tumour...

journal_title：British journal of anaesthesia

authors： Tedore T

更新日期：2015-12-01 00:00:00

abstract：:The pharmaceutical formulation of Althesin was shown to have a weak allergenic potential in the guinea pig maximization test. Alphadolone and alphaxalone acetate were found to be devoid of such potential, while the status of Cremophor EL remained equivocal. ...

journal_title：British journal of anaesthesia

authors： Tachon P,Descotes J,Laschi-Loquerie A,Guillot JP,Evreux JC

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...

journal_title：British journal of anaesthesia

authors： Marty AP,Schmelzer S,Thomasin RA,Braun J,Zalunardo MP,Spahn DR,Breckwoldt J

更新日期：2020-07-01 00:00:00

abstract：:We have examined the role of benzodiazepine receptors in nitrous oxide-induced neuronal depression in rats. The changes in neuronal excitability induced by nitrous oxide and the benzodiazepine inverse agonist, Ro15-4513, were monitored by measurement of visual evoked potentials (VEP). Administration of Ro15-4513 10 mg...

journal_title：British journal of anaesthesia

authors： Dzoljic M,Erdmann W,Dzoljic MR

更新日期：1996-10-01 00:00:00

abstract：:Bioactive substances in fresh frozen plasma (FFP) are considered to be related to adverse reactions after transfusion, particularly in septic or traumatized patients. Therefore, we analysed the concentration of various bioactive substances (histamine, eosinophil cationic protein, eosinophil protein X, myeloperoxidase ...

journal_title：British journal of anaesthesia

authors： Nielsen HJ,Reimert C,Pedersen AN,Dybkjoer E,Brünner N,Alsbjørn B,Skov PS

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Rapid, preoperative identification of patients with the highest risk for medical complications is necessary to ensure that limited infrastructure and human resources are directed towards those most likely to benefit. Existing risk scores either lack specificity at the patient level or utilise the American So...

journal_title：British journal of anaesthesia

authors： Hill BL,Brown R,Gabel E,Rakocz N,Lee C,Cannesson M,Baldi P,Olde Loohuis L,Johnson R,Jew B,Maoz U,Mahajan A,Sankararaman S,Hofer I,Halperin E

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:We defined the nature of the pharmacological interaction after intrathecal co-administration of ginsenosides with clonidine, and clarified the contribution of the α-2 adrenoceptors on the effect of ginsenosides. METHODS:Pain was evoked by injection of a formalin solution (5%, 50 μl) into the hindpaw of male...

journal_title：British journal of anaesthesia

authors： Yoon MH,Huang LJ,Choi JI,Lee HG,Kim WM,Kim CM

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Blood flow patterns are important modifiers of platelet interactions with plasma coagulation factors. However, it is not feasible to evaluate rheological effects of haemodilution on coagulation using conventional coagulation testing. METHODS:We evaluated thrombus formation with a microchip-based flow-chambe...

journal_title：British journal of anaesthesia

authors： Ogawa S,Ohnishi T,Hosokawa K,Szlam F,Chen EP,Tanaka KA

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Studies of the accuracy of partial rebreathing measurements of pulmonary blood flow (PBF) in patients with abnormal lungs have not fully explained the sources of error. METHODS:We used computer models of emphysema and pulmonary embolism incorporating both ventilation-perfusion (V/Q) and ventilation-volume (...

journal_title：British journal of anaesthesia

authors： Yem JS,Turner MJ,Baker AB

更新日期：2006-11-01 00:00:00

abstract：:The effects of laudanosine, a metabolite of atracurium, on the behaviour of conscious mice, rats and dogs, and on cardiovascular function in conscious and anaesthetized dogs have been evaluated: EEG studies were performed in anaesthetized dogs. In mice and rats, i.v. bolus doses of laudanosine 10-20 mg kg-1, caused co...

journal_title：British journal of anaesthesia

authors： Chapple DJ,Miller AA,Ward JB,Wheatley PL

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Propofol can scavenge free radicals because it has a chemical structure similar to antioxidants. METHODS:We examined if free radical scavenging occurs with propofol during CABG operations. We studied 24 patients undergoing CABG surgery for triple vessel disease, randomized into two groups. After induction o...

journal_title：British journal of anaesthesia

authors： Sayin MM,Ozatamer O,Taşöz R,Kilinç K,Unal N

更新日期：2002-08-01 00:00:00