Propofol attenuates myocardial lipid peroxidation during coronary artery bypass grafting surgery.

abstract：:We report a case of massive pulmonary embolism occurring at the time of graft reperfusion in a patient undergoing orthotopic liver transplantation. The clinical diagnosis of pulmonary embolus was aided by on-table echocardiography. Cardiopulmonary bypass and surgical embolectomy prevented her death. We discuss the dif...

journal_title：British journal of anaesthesia

authors： Manji M,Isaac JL,Bion J

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Hip fracture is a condition with high mortality and morbidity in elderly frail patients. Intraoperative fluid optimization may be associated with benefit in this population. We investigated whether intraoperative fluid management using pulse-contour analysis cardiac monitoring, compared with standard care in...

journal_title：British journal of anaesthesia

authors： Moppett IK,Rowlands M,Mannings A,Moran CG,Wiles MD,NOTTS Investigators.

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction might be involved in the development of cerebral vasospasm after aneurysmal subarachnoid haemorrhage (SAH). METHODS:This prospective observational study of 48 SAH subjects and 23 control subjects examined associations between reactive hyperaemia index (RHI) measured by peripheral art...

journal_title：British journal of anaesthesia

authors： Bergström A,Staalsø JM,Romner B,Olsen NV

更新日期：2014-02-01 00:00:00

abstract：:We have examined the effects of sedation with midazolam 0.1 mg kg-1 and reversal with flumazenil 0.5 mg on beat-to-beat heart rate (HR) variability (HRV), systolic arterial pressure (SAP), finger photoplethysmograph amplitude (PLA) and impedence pneumography in eight volunteers. With the onset of sedation there was a ...

journal_title：British journal of anaesthesia

authors： Galletly DC,Williams TB,Robinson BJ

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Assessments of labour pain focus on pain intensity, not on duration. We aimed to assess the importance labouring women apply to pain intensity and duration before labour and post-delivery. METHODS:Forty healthy women scheduled for labour induction were enrolled in this institutional review board-approved, p...

journal_title：British journal of anaesthesia

authors： Carvalho B,Hilton G,Wen L,Weiniger CF

更新日期：2014-09-01 00:00:00

abstract：:We have studied the effects of alfentanil administered intrathecally on somatosympathetic reflexes evoked by stimulation of radial and tibial nerves in 10 anaesthetized and paralysed dogs. In five animals, alfentanil was administered in doses of 100, 100, 200 and 400 micrograms in 0.8 ml and 800 micrograms in 1.6 ml p...

journal_title：British journal of anaesthesia

authors： Wang C,Chakrabarti MK,Whitwam JG

更新日期：1992-05-01 00:00:00

abstract：:Metoclopramide has been used for almost 40 yr to prevent postoperative nausea and vomiting (PONV). We have reviewed the efficacy and safety of metoclopramide for the prevention of PONV. A systematic search (MEDLINE, EMBASE, manufacturers' databases, hand searching, bibliographies, all languages, up to June 1998) was p...

journal_title：British journal of anaesthesia

authors： Henzi I,Walder B,Tramèr MR

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Risks and costs of allogeneic blood transfusions mandate strategies to reduce blood loss in surgery. The objective of this study was to assess the efficacy of antifibrinolytic treatment in reducing perioperative blood loss during total knee replacement. METHODS:A double-blind, randomized and placebo-control...

journal_title：British journal of anaesthesia

authors： Camarasa MA,Ollé G,Serra-Prat M,Martín A,Sánchez M,Ricós P,Pérez A,Opisso L

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The ilioinguinal/iliohypogastric nerve block is a popular regional anaesthetic technique for children undergoing inguinal surgery. The success rate is only 70-80% and complications may occur. A prospective randomized double-blinded study was designed to compare the use of ultrasonography with the conventiona...

journal_title：British journal of anaesthesia

authors： Willschke H,Marhofer P,Bösenberg A,Johnston S,Wanzel O,Cox SG,Sitzwohl C,Kapral S

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:We explored whether a previously successful initiative to improve first-case on-time starts succeeded because (i) preoperative steps started earlier (but the process did not necessarily improve) or (ii) the process was brought into better control. METHODS:We analysed 35 months of data comprising 28 882 firs...

journal_title：British journal of anaesthesia

authors： Tiwari V,Ehrenfeld JM,Sandberg WS

更新日期：2018-11-01 00:00:00

abstract：:The effects of some anaesthetics and other agents used in anaesthetic practice on the neuromuscular blocking activity of cumulative doses of Org NC 45 have been studied in cats anaesthetized with chloralose. As expected from studies with other neuromuscular blocking drugs, both inhalation and i.v. anaesthetics reduced...

journal_title：British journal of anaesthesia

authors： McIndewar IC,Marshall RJ

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Dynamic arterial elastance (Eadyn) has been proposed as an indicator of vascular tone that predicts the decrease in arterial pressure in response to changes in norepinephrine (NE). The purpose of this study was to determine whether Eadyn measured by uncalibrated pulse contour analysis (UPCA) can predict a de...

journal_title：British journal of anaesthesia

authors： Bar S,Leviel F,Abou Arab O,Badoux L,Mahjoub Y,Dupont H,Lorne E,Guinot PG

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Overt stroke after non-cardiac surgery has a substantial impact on the duration and quality of life. Covert stroke in the non-surgical setting is much more common than overt stroke and is associated with an increased risk of cognitive decline and dementia. Little is known about covert stroke after non-cardia...

journal_title：British journal of anaesthesia

authors： Mrkobrada M,Hill MD,Chan MT,Sigamani A,Cowan D,Kurz A,Sessler DI,Jacka M,Graham M,Dasgupta M,Dunlop V,Emery DJ,Gulka I,Guyatt G,Heels-Ansdell D,Murkin J,Pettit S,Sahlas DJ,Sharma M,Sharma M,Srinathan S,St John P

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:None of the currently available hypnosis monitoring systems have evaluated balanced xenon anaesthesia. We investigated the performance of the bispectral index (BIS) and the composite A-line autoregressive index (cAAI) while comparing balanced xenon with sevoflurane anaesthesia. METHODS:Sixty patients underg...

journal_title：British journal of anaesthesia

authors： Fahlenkamp AV,Peters D,Biener IA,Billoet C,Apfel CC,Rossaint R,Coburn M

更新日期：2010-09-01 00:00:00

abstract：:We have studied 13 patients with diabetic nephropathy and 13 patients with uraemia of other origin undergoing renal transplantation, and 12 control patients undergoing general surgery. QTc dispersion and maximum QTc interval were calculated from the 12-lead ECG, and cardiovascular autonomic function tests were perform...

journal_title：British journal of anaesthesia

authors： Kirvelä M,Yli-Hankala A,Lindgren L

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Opioids can increase sensitivity to noxious stimuli and cause opioid-induced hyperalgesia. We performed a systematic review to evaluate the clinical consequences of intra-operative doses of opioid. METHODS:We identified randomized controlled trials which compared intra-operative opioid to lower doses or pla...

journal_title：British journal of anaesthesia

authors： Fletcher D,Martinez V

更新日期：2014-06-01 00:00:00

abstract：:Chronic pain affects ∼20% of the European population and is commoner in women, older people, and with relative deprivation. Its management in the community remains generally unsatisfactory, partly because of lack of evidence for effective interventions. Epidemiological study of chronic pain, through an understanding o...

journal_title：British journal of anaesthesia

authors： van Hecke O,Torrance N,Smith BH

更新日期：2013-07-01 00:00:00

abstract：:Protein kinase C (PKC) is a key regulatory enzyme that has been implicated as a molecular target for the action of general anaesthetics. We have determined the effects of halothane on the translocation and down-regulation of conventional PKC (cPKC) by analysing the subcellular distribution of PKC activity, [3H]phorbol...

journal_title：British journal of anaesthesia

authors： Hemmings HC Jr,Adamo AI

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:The AirWay Scope (AWS) is a fibreoptic device that allows for intubation without alignment of the oral, pharyngeal, and tracheal axes. It may be useful for patients with an unstable cervical-spine (C-spine) or when C-spine movement is undesirable. This study was conducted to fluoroscopically evaluate upper C...

journal_title：British journal of anaesthesia

authors： Maruyama K,Yamada T,Kawakami R,Hara K

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Emotional information has the ability to alter the formation and strength of a memory ('memory modulation'). Memory modulation by negative emotion is mediated by the amygdala. It is not known how gamma aminobutyric acid (GABA)ergic drugs affect the processes involved in memory modulation. This study investig...

journal_title：British journal of anaesthesia

authors： Pryor KO,Veselis RA,Reinsel RA,Feshchenko VA

更新日期：2004-09-01 00:00:00

abstract：:Robotic surgery pushes the frontiers of innovation in healthcare technology towards improved clinical outcomes. We discuss the evolution to five generations of robotic surgical platforms including stereotactic, endoscopic, bioinspired, microbots on the millimetre scale, and the future development of autonomous systems...

journal_title：British journal of anaesthesia

authors： Ashrafian H,Clancy O,Grover V,Darzi A

更新日期：2017-12-01 00:00:00

abstract：:We studied psychomotor performance in 10 healthy volunteers during recovery after a target-controlled infusion of propofol. Choice reaction time, dual task tracking with secondary reaction time and a within-list recognition task were assessed at target blood propofol concentrations of 0.8, 0.4 and 0.2 microgram ml-1. ...

journal_title：British journal of anaesthesia

authors： Grant SA,Murdoch J,Millar K,Kenny GN

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:Myocardial injury after noncardiac surgery is common, although the exact pathophysiology is unknown. It is plausible that hypotension after surgery is relevant for the development of myocardial injury. The authors evaluated whether low mean arterial pressures (MAPs) after surgery are related to an increased ...

journal_title：British journal of anaesthesia

authors： van Lier F,Wesdorp FHIM,Liem VGB,Potters JW,Grüne F,Boersma H,Stolker RJ,Hoeks SE

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Data on bupivacaine concentrations in the cerebral spinal fluid (CSF) during spinal anaesthesia are scarce. The purpose of this study was to determine the concentration of bupivacaine in the lumbar CSF of patients with an adequate level of spinal anaesthesia after injection of plain bupivacaine 0.5%. METHOD...

journal_title：British journal of anaesthesia

authors： Ruppen W,Steiner LA,Drewe J,Hauenstein L,Brugger S,Seeberger MD

更新日期：2009-06-01 00:00:00

abstract：:Patients with metastatic carcinoid tumours often undergo surgical procedures to reduce the tumour burden and associated debilitating symptoms. These procedures and anaesthesia can precipitate a life-threatening carcinoid crisis. To assess perioperative outcomes, we studied retrospectively the medical records of adult ...

journal_title：British journal of anaesthesia

authors： Kinney MA,Warner ME,Nagorney DM,Rubin J,Schroeder DR,Maxson PM,Warner MA

更新日期：2001-09-01 00:00:00

abstract：:To assess the effect of sevoflurane anaesthesia on hepatocellular integrity, we measured plasma concentrations of glutathione S-transferase (GST) before anaesthesia and 1, 3, 6 and 24 h after the end of anaesthesia in 41 healthy, Japanese patients undergoing elective, body surface surgery. Sevoflurane (approximately 1...

journal_title：British journal of anaesthesia

authors： Ray DC,Bomont R,Mizushima A,Kugimiya T,Forbes Howie A,Beckett GJ

更新日期：1996-09-01 00:00:00

abstract：:We have documented the changes in gas exchange, haemodynamic state and associated physiological variables which occurred after graft reperfusion in 20 patients undergoing uncomplicated orthotopic liver transplantation. Gas exchange was measured during constant ventilation using a metabolic monitor. After reperfusion, ...

journal_title：British journal of anaesthesia

authors： Walsh TS,Hopton P,Garden OJ,Lee A

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:There has been increasing use of invasive techniques, such as extracorporeal organ support, in intensive care units (ICU), and declining autopsy rates. Thus, new measures are needed to maintain high-quality standards. We investigated the potential of computed tomography (CT)-based virtual autopsy to substitu...

journal_title：British journal of anaesthesia

authors： Wichmann D,Heinemann A,Zähler S,Vogel H,Höpker W,Püschel K,Kluge S

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:The pulmonary artery catheter is invasive and may cause serious complications. A safe method of cardiac output (CO) measurement is needed. We have assessed the accuracy and reliability of a recently marketed self-calibrating arterial pulse contour CO monitoring system (FloTrac/Vigileo) in end-stage liver fai...

journal_title：British journal of anaesthesia

authors： Biancofiore G,Critchley LA,Lee A,Bindi L,Bisà M,Esposito M,Meacci L,Mozzo R,DeSimone P,Urbani L,Filipponi F

更新日期：2009-01-01 00:00:00

abstract：:Midazolam is often used for paediatric premedication. We have compared two methods of administering midazolam intranasally in 44 surgical day-case children allocated randomly to receive midazolam 0.2 mg kg-1 as drops or midazolam 0.1 mg kg-1 from an intranasal spray device. Behaviour was recorded on a four-point scale...

journal_title：British journal of anaesthesia

authors： Griffith N,Howell S,Mason DG

更新日期：1998-12-01 00:00:00