Regional anaesthesia and analgesia: relationship to cancer recurrence and survival.

abstract：BACKGROUND:Cardiac surgery with cardiopulmonary bypass (CPB) is commonly perceived as a risk factor for decline in renal function, especially in patients with preoperative renal dysfunction. There are few data on the effects of CPB on renal function in patients with mild preoperative renal dysfunction. The purpose of t...

journal_title：British journal of anaesthesia

authors： Loef BG,Henning RH,Navis G,Rankin AJ,van Oeveren W,Ebels T,Epema AH

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:We studied the potential neuroprotective effects of halothane and desflurane, compared with the awake state, on infarct size following 2 h of intraluminal middle cerebral artery occlusion (MCAo) and 22 h of reperfusion. METHODS:Male Sprague-Dawley rats were anaesthetized with desflurane or halothane, intuba...

journal_title：British journal of anaesthesia

authors： Haelewyn B,Yvon A,Hanouz JL,MacKenzie ET,Ducouret P,Gérard JL,Roussel S

更新日期：2003-09-01 00:00:00

abstract：:The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally painful orthopaedic hand surgery (trapeziectomy). Further investigations revealed a lifelong history...

journal_title：British journal of anaesthesia

authors： Habib AM,Okorokov AL,Hill MN,Bras JT,Lee MC,Li S,Gossage SJ,van Drimmelen M,Morena M,Houlden H,Ramirez JD,Bennett DLH,Srivastava D,Cox JJ

更新日期：2019-08-01 00:00:00

abstract：:Using an airway management training model, we have assessed anaesthesia personnel in their use of correct cricoid force and ability to retain this skill after a short training programme. A perspex device, working on a hydraulic principle, was used to measure cricoid pressure when applied to the model. After initial as...

journal_title：British journal of anaesthesia

authors： Ashurst N,Rout CC,Rocke DA,Gouws E

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:The population in the UK is growing older and the number of elderly patients cared for on intensive care units (ICU) is increasing. This study was designed to identify risk factors for mortality in critically ill patients of >80 yr of age after surgery. METHODS:We identified 275 patients, aged 80 yr or grea...

journal_title：British journal of anaesthesia

authors： Ford PN,Thomas I,Cook TM,Whitley E,Peden CJ

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:This study compared the efficacy of topical anaesthesia with levobupivacaine 0.75% vs lidocaine 2% during cataract surgery by phacoemulsification. METHODS:A prospective, randomized, double-blind study comparing two agents for topical anaesthesia in cataract surgery. Two hundred and forty-six consecutive pat...

journal_title：British journal of anaesthesia

authors： Fernández SA,Dios E,Diz JC

更新日期：2009-02-01 00:00:00

abstract：:Simple methods are described for computing the variables derived from the Siggaard-Andersen nomogram, where the in vitro buffer line is either established by direct measurement or calculated from measurements of pH, Pco2 and haemoglobin. Calculations are performed using the equation of the pH-log Pco2 buffer line, the...

journal_title：British journal of anaesthesia

authors： Blackburn JP,Preston TD,Strickland DA

更新日期：1975-04-01 00:00:00

abstract：:The pressor and catecholamine responses to laryngoscopy and intubation were studied in nine patients with pregnancy-induced hypertension (PIH) and in eight normotensive controls. Five of the PIH patients had received oral labetalol as antihypertensive therapy. Mean arterial pressure (MAP) increased significantly from ...

journal_title：British journal of anaesthesia

authors： Lavies NG,Meiklejohn BH,May AE,Achola KJ,Fell D

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Anterograde, but not retrograde, amnesia has been demonstrated following midazolam administration. However, there have been no studies investigating whether or not immediate retrograde amnesia can be produced with midazolam. METHODS:After ethics committee approval and consent, 40 adult patients undergoing s...

journal_title：British journal of anaesthesia

authors： Bulach R,Myles PS,Russnak M

更新日期：2005-03-01 00:00:00

abstract：:Bilateral superior laryngeal nerve block was combined with topical application of local anaesthetic 140 times in 135 patients to anaesthetize the upper airway and facilitate tracheal intubation, laryngeal instrumentation, or to diminish the response to the endotracheal tube, in a patient already intubated. The techniq...

journal_title：British journal of anaesthesia

authors： Gotta AW,Sullivan CA

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:We previously demonstrated that i.v. emulsified isoflurane induces general anaesthesia in animals. In this study, we compared the pharmacokinetics of emulsified isoflurane given as i.v. bolus and as infusion in beagle dogs. METHODS:Sixteen beagle dogs were assigned randomly to a bolus group comprising three...

journal_title：British journal of anaesthesia

authors： Yang XL,Zhang WS,Liu J,Yang ZB,Jiang XH

更新日期：2013-01-01 00:00:00

abstract：:We have investigated 296 inpatients in a single-blind observer study to determine the incidence, degree and duration of hypoxaemia during anaesthesia. The clinical recognition of hypoxaemia, period of time until recognition and risk factors were studied. Oxygen saturation (Spo2) was monitored continuously with a pulse...

journal_title：British journal of anaesthesia

authors： Moller JT,Johannessen NW,Berg H,Espersen K,Larsen LE

更新日期：1991-04-01 00:00:00

abstract：:We have measured plasma concentrations of bupivacaine after ilioinguinal block in children of different sizes. We studied 14 children with weights 10-15 kg and 17 children with weights 15-30 kg. Each child received 0.5% bupivacaine 0.25 ml kg-1 (1.25 mg kg-1) (Carbostesin, Astra, Germany). Venous blood was obtained be...

journal_title：British journal of anaesthesia

authors： Smith T,Moratin P,Wulf H

更新日期：1996-03-01 00:00:00

abstract：:Hypertensive patients were monitored for myocardial ischaemia during anaesthesia and surgery with the V5 lead of a standard electrocardiograph. Myocardial ischaemia was detected in 11 of 39 untreated hypertensive patients and in four of seven receiving therapy with a diuretic, but in none of 44 receiving atenolol. Fou...

journal_title：British journal of anaesthesia

authors： Stone JG,Foëx P,Sear JW,Johnson LL,Khambatta HJ,Triner L

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Paravertebral regional anaesthesia is used to treat pain after several surgical procedures. This study aimed to improve on our first published ultrasound-guided approach to the paravertebral space (PVS) and to investigate a possible discrepancy between the needle, catheter, and contrast dye position. METHOD...

journal_title：British journal of anaesthesia

authors： Luyet C,Herrmann G,Ross S,Vogt A,Greif R,Moriggl B,Eichenberger U

更新日期：2011-02-01 00:00:00

abstract：:Arterial blood and expired gas samples were taken from 20 patients before operation and on the first day after upper abdominal surgery. After operation the patients were studied breathing air and also breathing 35% oxygen from a venturi-type mask. Preoperative Pao2 with age was exaggerated by operation. Pao2 after ope...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:The purpose of this prospective study was to assess the blood-sparing effect, the quality of analgesia, and the incidence of side-effects of a low-dose regime of intrathecal opioids (ITO) when compared with those of a high-dose regime in scoliosis surgery in children. METHODS:Forty-six children were randoml...

journal_title：British journal of anaesthesia

authors： Eschertzhuber S,Hohlrieder M,Keller C,Oswald E,Kuehbacher G,Innerhofer P

更新日期：2008-04-01 00:00:00

abstract：:Arterial PO2 (PaO2) has been related to inspired oxygen concentration (FIO2 range 0.21-0.60) in 20 patients, breathing spontaneously, while recovering from a range of conditions treated in an intensive therapy unit. There was a highly significant linear trend (P < 0.001) for the mean venous admixture ("virtual shunt")...

journal_title：British journal of anaesthesia

authors： Petros AJ,Doré CJ,Nunn JF

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Perioperative neurocognitive disorders (PND) result in long-term morbidity and mortality with no effective interventions available. Because interleukin-6 (IL-6), a pro-inflammatory cytokine, is consistently up-regulated by trauma, including after surgery, we determined whether IL-6 is a putative therapeutic ...

journal_title：British journal of anaesthesia

authors： Hu J,Feng X,Valdearcos M,Lutrin D,Uchida Y,Koliwad SK,Maze M

更新日期：2018-03-01 00:00:00

abstract：:In a prospective double-blind study, single dose lumbar extradural blockade was instituted in 80 healthy male patients undergoing lower abdominal surgery. Patients were assigned randomly to one of four groups. Each group received treatment with 0.5% bupivacaine 20 ml containing adrenaline 1:200 000. To this solution w...

journal_title：British journal of anaesthesia

authors： Rucci FS,Cardamone M,Migliori P

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Data on bupivacaine concentrations in the cerebral spinal fluid (CSF) during spinal anaesthesia are scarce. The purpose of this study was to determine the concentration of bupivacaine in the lumbar CSF of patients with an adequate level of spinal anaesthesia after injection of plain bupivacaine 0.5%. METHOD...

journal_title：British journal of anaesthesia

authors： Ruppen W,Steiner LA,Drewe J,Hauenstein L,Brugger S,Seeberger MD

更新日期：2009-06-01 00:00:00

abstract：:In a double-blind, placebo-controlled three-way cross over study, the efficacy of Ro 15-1788 200 mg, a new benzodiazepine antagonist, in blocking the amnesic, cognitive, psychomotor and subjective effects of diazepam 20 mg, was investigated in a group of six healthy male volunteers. The amnesic effects of diazepam wer...

journal_title：British journal of anaesthesia

authors： O'Boyle C,Lambe R,Darragh A,Taffe W,Brick I,Kenny M

更新日期：1983-04-01 00:00:00

abstract：:We have recently reported that continuous administration of butorphanol into the brachial plexus neurovascular sheath provided superior analgesia compared with that obtained with continuous i.v. administration. Furthermore, we found that analgesia was most pronounced when a mixture of mepivacaine and butorphanol was g...

journal_title：British journal of anaesthesia

authors： Wajima Z,Shitara T,Nakajima Y,Kim C,Kobayashi N,Kadotani H,Adachi H,Ishikawa G,Kaneko K,Inoue T,Ogawa R

更新日期：1997-01-01 00:00:00

abstract：Background:Blood lactate is a strong predictor of mortality, and repeated blood lactate assays are recommended during surgery in high-risk patients. We hypothesized that the use of intravascular microdialysis incorporated in a central venous catheter would be interchangeable with the reference blood gas technique to mo...

journal_title：British journal of anaesthesia

authors： Gouëzel C,Lorne E,Bonnet V,Fradin S,Saplacan V,Gérard JL,Hanouz JL,Fellahi JL,Fischer MO,FHT (French Hemodynamic Team).

更新日期：2017-12-01 00:00:00

abstract：:We report two patients who developed skin necrosis following an intramuscular injection of non-steroidal anti-inflammatory drug into the anteriolateral area of their thigh. Both patients required further multiple operations and one developed life threatening septicaemia. They were left with disfiguring scars. Skin nec...

journal_title：British journal of anaesthesia

authors： McGee AM,Davison PM

更新日期：2002-01-01 00:00:00

abstract：:We have studied the pharmacokinetics of lignocaine in children after local infiltration for cleft palate surgery. After induction of anaesthesia, lignocaine 2.5 mg kg-1 with adrenaline 1:200,000 was injected into the palate. Blood samples were collected before and at 2, 5, 10, 15, 20, 30, 60 and 120 min after infiltra...

journal_title：British journal of anaesthesia

authors： Michael S,Barker I,Henderson P,Griffiths RW,Reilly CS

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Chronic pain is no longer an effective warning system, but a syndrome with co-morbidities and many causes, needing a careful evaluation. Questions remain about the pain behaviour of chronic pain patients compared with patients with acute pain, or healthy subjects that we investigated. METHODS:We compared th...

journal_title：British journal of anaesthesia

authors： Tuna T,Van Obbergh L,Van Cutsem N,Engelman E

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:The ultrasound cardiac output monitor (USCOM) is a continuous wave Doppler system designed to measure cardiac output (CO) non-invasively and intermittently either from the pulmonary or from the aortic valve. USCOM scan quality is critical to obtaining reliable data and during anaesthesia it is said to deteri...

journal_title：British journal of anaesthesia

authors： Huang L,Critchley LA

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:There has been a renewed interest in nitric oxide donor drugs, such as nitroglycerin, delivered by the inhalational route for treatment of pulmonary arterial hypertension (PAH). We investigated the acute effects of inhaled nitroglycerin on pulmonary and systemic haemodynamics in children with PAH associated ...

journal_title：British journal of anaesthesia

authors： Goyal P,Kiran U,Chauhan S,Juneja R,Choudhary M

更新日期：2006-08-01 00:00:00

abstract：:Alcuronium 0.16 mg kg-1 was used to provide neuromuscular blockade in patients with chronic renal failure undergoing renal transplantation. Relaxation was found to be adequate for intubation and surgery. There were minimal alterations to cardiovascular variables. The dose required was small, and complete reversal occu...

journal_title：British journal of anaesthesia

authors： Kaushik S,Grover VK,Singh H,Yadav RV

更新日期：1984-11-01 00:00:00