Postoperative hypoxaemia and oxygen therapy.

abstract：BACKGROUND:The safe performance of regional anaesthesia (RA) requires theoretical knowledge and good manual skills. Virtual reality (VR)-based simulators may offer trainees a safe environment to learn and practice different techniques. However, currently available VR simulators do not consider individual anatomy, which...

journal_title：British journal of anaesthesia

authors： Grottke O,Ntouba A,Ullrich S,Liao W,Fried E,Prescher A,Deserno TM,Kuhlen T,Rossaint R

更新日期：2009-10-01 00:00:00

abstract：:Twelve hydrocephalic patients undergoing hydrodynamic studies and shunt procedures during general anaesthesia were subjected to short term observations of the cerebrovascular effects of isoflurane. Intraventricular pressure (IVP), arterial pressure (AP); cerebral perfusion pressure (CPP = AP-IVP), end-tidal PCO2, Cere...

journal_title：British journal of anaesthesia

authors： Lundar T,Lindegaard KF,Refsum L,Rian R,Nornes H

更新日期：1987-10-01 00:00:00

abstract：:The action of halothane on the pulmonary vasoconstrictor response to unilateral alveolar hypoxia was studied in two groups of dogs. In the first group the redistribution of blood flow between the two lungs was studied with a radioactive isotope method, which provided intermittent measurements, whilst in the second gro...

journal_title：British journal of anaesthesia

authors： Sykes MK,Gibbs JM,Loh L,Marin JB,Obdrzalek J,Arnot RN

更新日期：1978-12-01 00:00:00

abstract：:The study was performed to determine the ED50 and ED95 of a continuous infusion of the emulsion formulation of propofol during 67% nitrous oxide anaesthesia in 57 patients premedicated with morphine sulphate 0.15 mg kg-1. Anaesthesia was induced with propofol 2 mg kg-1, and maintained before incision with a fixed-rate...

journal_title：British journal of anaesthesia

authors： Spelina KR,Coates DP,Monk CR,Prys-Roberts C,Norley I,Turtle MJ

更新日期：1986-10-01 00:00:00

abstract：:In theory, setting an infrared multi-gas analyser to measure a volatile anaesthetic different from that in the sampled gas mixture may cause interference with carbon dioxide and nitrous oxide readings. The theory was investigated during evaluation of the Dräger Cicero EM anaesthetic workstation for the Medical Devices...

journal_title：British journal of anaesthesia

authors： Wilkes AR,Mapleson WW

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:The significance of IgE antibodies to neuromuscular blocking agent (NMBA)-induced anaphylactic reactions during anaesthesia is unclear. We investigated the relevance of IgE to rocuronium using an in vitro technique. METHODS:Serum samples from 61 patients with anaphylactic reactions during anaesthesia were i...

journal_title：British journal of anaesthesia

authors： Aalberse RC,Kleine Budde I,Mulder M,Stapel SO,Paulij W,Leynadier F,Hollmann MW

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Abnormal serum sodium concentrations are common in patients presenting for surgery. It remains unclear whether these abnormalities are independent risk factors for postoperative mortality. METHODS:This is a secondary analysis of the European Surgical Outcome Study (EuSOS) that provided data describing 46 53...

journal_title：British journal of anaesthesia

authors： Cecconi M,Hochrieser H,Chew M,Grocott M,Hoeft A,Hoste A,Jammer I,Posch M,Metnitz P,Pelosi P,Moreno R,Pearse RM,Vincent JL,Rhodes A,European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society o

更新日期：2016-01-01 00:00:00

abstract：:Experiments were performed on rats using two analgesimetric tests (tail-flick; hot-plate) before and after injection i.v. of graded doses of aprotinin (12.5, 25.0 and 50 KIU g-1). A dose-related analgesic effect was noted with both tests. Prior administration of naloxone 0.001 mg g-1 i.p. inhibited the analgesic actio...

journal_title：British journal of anaesthesia

authors： Novelli GP,Pieraccioli E,Peduto VA,Festimanni F

更新日期：1980-11-01 00:00:00

abstract：:Cytokine synthesis and release is an essential component of the innate immune system, but inappropriate, excessive production results in a generalized systemic inflammatory response which damages distant organs. Recent research has identified an immunomodulatory function of the vagus nerve whereby activation of the ef...

journal_title：British journal of anaesthesia

authors： Johnston GR,Webster NR

更新日期：2009-04-01 00:00:00

abstract：:Patients with Munchausen's syndrome often undergo multiple surgical operations under general anaesthesia. They tend to have multiple exposures to routinely used anaesthetic agents. A patient with Munchausen's syndrome who developed an anaphylactoid reaction to thiopentone is described and the importance of obtaining p...

journal_title：British journal of anaesthesia

authors： Frater RA,Lew JK

更新日期：1987-11-01 00:00:00

abstract：:In the postoperative period fifty-six healthy patients undergoing cholecystectomy or operations for duodenal ulcer, received, in a randomized order, i.m., "high-level" or "low-level" extradural morphine. Thirty-five per cent in the i.m. group, 33% in the high-level group and 50% in the low-level group suffered urinary...

journal_title：British journal of anaesthesia

authors： Petersen TK,Husted SE,Rybro L,Schurizek BA,Wernberg M

更新日期：1982-11-01 00:00:00

abstract：:A new type of intra-arterial oxygen electrode was evaluated. In 14 patients, undergoing one-lung ventilation for thoracic surgery, the electrode was inserted into the radial artery and changes in PaO2 were recorded continuously. Methods of improving PaO2 during one-lung ventilation were demonstrated. ...

journal_title：British journal of anaesthesia

authors： Armstrong RF,Hutchinson JM,Lincoln C,Ingram D,Soutter L

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Early postoperative negative behaviour in preschool children after general anaesthesia is a common problem. The distinction between emergence delirium (ED) and pain is difficult, but management differs between the two. The aim of the current analysis was to identify individual observational variables that ca...

journal_title：British journal of anaesthesia

authors： Somaini M,Engelhardt T,Fumagalli R,Ingelmo PM

更新日期：2016-03-01 00:00:00

abstract：:Spontaneous movements are sometimes observed of the arm into which rocuronium is administered. In order to assess a possible relationship between these movements and pain, we injected in 10 awake, ASA I patients, in a double-blind manner, both rocuronium 1 ml (10 mg) and 0.9% NaCI 1 ml (placebo), with a 30-s interval ...

journal_title：British journal of anaesthesia

authors： Borgeat A,Kwiatkowski D

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnoea (OSA) affects ~9-24% of the general population, and 90% remain undiagnosed. Those patients with undiagnosed moderate-to-severe OSA may be associated with an increased risk of perioperative complications. Our objective was to evaluate the proportion of surgical patients with undiagnos...

journal_title：British journal of anaesthesia

authors： Singh M,Liao P,Kobah S,Wijeysundera DN,Shapiro C,Chung F

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Signalling of several G-protein-coupled receptors of the Gq/11 family is time-dependently inhibited by local anaesthetics (LAs). Since LA-induced modulation of muscarinic m1 and m3 receptor function may explain their beneficial effects in clinical practice, such as decreased postoperative cognitive dysfuncti...

journal_title：British journal of anaesthesia

authors： Picardi S,Stevens MF,Hahnenkamp K,Durieux ME,Lirk P,Hollmann MW

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Inconsistent and poorly coordinated systems of tracheostomy care commonly result in frustrations, delays, and harm. Quality improvement strategies described by exemplar hospitals of the Global Tracheostomy Collaborative have potential to mitigate such problems. This 3 yr guided implementation programme inves...

journal_title：British journal of anaesthesia

authors： McGrath BA,Wallace S,Lynch J,Bonvento B,Coe B,Owen A,Firn M,Brenner MJ,Edwards E,Finch TL,Cameron T,Narula A,Roberson DW

更新日期：2020-07-01 00:00:00

abstract：:We have investigated 296 inpatients in a single-blind observer study to determine the incidence, degree and duration of hypoxaemia during anaesthesia. The clinical recognition of hypoxaemia, period of time until recognition and risk factors were studied. Oxygen saturation (Spo2) was monitored continuously with a pulse...

journal_title：British journal of anaesthesia

authors： Moller JT,Johannessen NW,Berg H,Espersen K,Larsen LE

更新日期：1991-04-01 00:00:00

abstract：:We studied 52 adults undergoing elective craniotomy, allocated randomly to one of three opioid treatments: alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 until dural closure (group Alf.); alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 for 2 h, then remifentanil 0.25 microgra...

journal_title：British journal of anaesthesia

authors： Sneyd JR,Whaley A,Dimpel HL,Andrews CJ

更新日期：1998-09-01 00:00:00

abstract：:Maternal haemorrhage is the leading cause of preventable maternal death worldwide and encompasses antepartum, intrapartum, and postpartum bleeding. This review highlights factors that predispose to severe bleeding, its management, and the most recent treatment and guidelines. Advances in obstetric care have provided p...

journal_title：British journal of anaesthesia

authors： Walfish M,Neuman A,Wlody D

更新日期：2009-12-01 00:00:00

abstract：Background.:Compromised tissue oxygenation is one of the root causes of dysfunction of various organs and postoperative complications. Oxygenation of different tissue beds may follow different patterns of change during physiological derangement. Methods.:Patients undergoing elective major posterior spine surgery parti...

journal_title：British journal of anaesthesia

authors： Meng L,Xiao J,Gudelunas K,Yu Z,Zhong Z,Hu X

更新日期：2017-04-01 00:00:00

abstract：:The serum vasopressin (S-AVP) concentration, serum sodium concentration and osmolality, central venous pressure and fluid balance were measured during 10-min periods in 32 patients undergoing transurethral resection of the prostate. Concentration of S-AVP was unaffected by uncomplicated resection; irrigant absorption ...

journal_title：British journal of anaesthesia

authors： Hahn RG,Rundgren M

更新日期：1989-09-01 00:00:00

abstract：:Fifteen patients (10 men and five women; mean age 67.3 yr) with a history of a recent (less than 1 yr) myocardial infarction underwent ambulatory ECG monitoring for 5 days after non-cardiac surgery. The duration, number and severity of ischaemic episodes were maximal within the first 12 h after surgery and again on th...

journal_title：British journal of anaesthesia

authors： Metzler H,Mahla E,Rotman B,Rehak P,Potisk S,List WF

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Investigators planning dose-response studies of neuromuscular blockers have rarely used a priori power analysis to determine the minimal sample size their protocols require. Institutional Review Boards and peer-reviewed journals now generally ask for this information. This study outlines a proposed method fo...

journal_title：British journal of anaesthesia

authors： Kopman AF,Lien CA,Naguib M

更新日期：2011-02-01 00:00:00

abstract：:Relative humidity of air produced by simple compressors used to drive ventilators was measured at different working pressures. At normal working pressures, a relative humidity of 100% was found and condensation occurred, mainly at the high pressure air/oxygen mixer valve. This resulted in blockages and loss of accurac...

journal_title：British journal of anaesthesia

authors： Conely JI,Railton R,MacKenzie AI

更新日期：1981-05-01 00:00:00

abstract：:The respiratory effects of a new strong analgesic, meptazinol, were compared with a placebo and with equianalgesic doses of morphine and pentazocine in a double-blind crossover trial in seven healthy volunteers. No significant change in the ventilatory response to rebreathing carbon dioxide was observed after meptazin...

journal_title：British journal of anaesthesia

authors： Jordan C,Lehane JR,Robson PJ,Jones JG

更新日期：1979-06-01 00:00:00

abstract：:The influence of sodium nitroprusside (SNP) on mitochondrial respiration was examined in rat liver mitochondria. The addition of SNP 1 mmol litre-1 during state 3 respiration inhibited the oxygen uptake by 63.4%. A mixture of SNP 1 mmol litre-1 and glutathione (GSH) 1 mmol litre-1 inhibited the oxygen uptake more mark...

journal_title：British journal of anaesthesia

authors： Nakamura S,Shin T,Hirokata Y,Shigematsu A

更新日期：1977-12-01 00:00:00

abstract：:We studied 20 patients undergoing thoracotomy, in a double-blind, placebo-controlled crossover trial of intercostal bupivacaine. Bupivacaine 0.25% was infused at 5 ml h-1 through each of two catheters placed in the intercostal space at operation. Mean (95% confidence limits) 24-h requirements for morphine from a patie...

journal_title：British journal of anaesthesia

authors： Dryden CM,McMenemin I,Duthie DJ

更新日期：1993-05-01 00:00:00

abstract：:BW 403C65, an isoquinolinium bisquaternary compound, was investigated for its neuromuscular blocking properties. In vitro in from preparations, low concentrations induced an increase in miniature endplate potentials (m.e.p.p.) frequency without altering their amplitude. With increasing concentrations m.e.p.p. frequenc...

journal_title：British journal of anaesthesia

authors： Post EL,Sokoll MD,Gergis SD,Dretchen KL,Cronnelly R

更新日期：1975-09-01 00:00:00

abstract：:Placental blood flow was measured during the first stage of normal labour using a xenon-133 clearance technique before and after segmental extradural analgesia. Analgesia was produced with 0.5% plain bupivacaine in eight patients and with 0.5% bupivacaine--adrenaline in 10 patients. Segmental extradural analgesia with...

journal_title：British journal of anaesthesia

authors： Jouppila R,Jouppila P,Hollmén A,Kuikka J

更新日期：1978-06-01 00:00:00