Sevoflurane has less effect than halothane on pulmonary afferent activity in the rabbit.

Abstract:

:We have compared the effects of sevoflurane and halothane on the discharge frequencies of 19 slowly adapting and four rapidly adapting lung receptors in the rabbit by recording from single vagal fibres. Both agents reduced the discharge frequency of slowly adapting receptors during expiration (P < 0.0005), halothane having a greater effect than sevoflurane (P < 0.0005). Neither agent had any effect on discharge frequency at the end of inspiration when discharge frequency is at a maximum. Neither agent affected the discharge frequency of rapidly adapting receptors.

journal_name

Br J Anaesth

authors

Moores C,Davies AS,Dallak M

doi

10.1093/bja/80.2.257

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

257-9

issue

2

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)40556-3

journal_volume

80

pub_type

杂志文章
  • Comparison of two ultrasound guided approaches for axillary vein catheterization: a randomized controlled non-inferiority trial.

    abstract:BACKGROUND:Axillary vein catheterization via a distal approach is an alternative to the proximal approach to axillary/subclavian vein catheterization under ultrasound (US) guidance. The aim of this trial was to compare the two approaches. METHODS:In a randomized single-centre study, all patients requiring central vein...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aev458

    authors: Buzançais G,Roger C,Bastide S,Jeannes P,Lefrant JY,Muller L

    更新日期:2016-02-01 00:00:00

  • Extradural analgesia for caesarean section: a comparison with general anaesthesia.

    abstract::Thirty-two patients received lumbar extradural anaesthesia for elective Caesarean section. The results obtained from this series were compared with those from a similar (control) group of parturients who received general anaesthesia. The extradural group (mothers and infants) were metabolically acidaemic relative to c...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/51.4.367

    authors: Downing JW,Houlton PC,Barclay A

    更新日期:1979-04-01 00:00:00

  • Dose-dependent effect of metoclopramide on cholinesterases and suxamethonium metabolism.

    abstract::In obstetric patients undergoing postpartum tubal ligation, we found that metoclopramide produced dose-dependent prolongation of suxamethonium-induced neuromuscular block. Mean block times after suxamethonium 1 mg kg-1 were 8.0 min, 9.83 min and 12.45 min for control and metoclopramide 10 mg and metoclopramide 20 mg g...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/65.2.220

    authors: Kao YJ,Tellez J,Turner DR

    更新日期:1990-08-01 00:00:00

  • Gram staining of protected pulmonary specimens in the early diagnosis of ventilator-associated pneumonia.

    abstract::We evaluated prospectively the use of Gram staining of protected pulmonary specimens to allow the early diagnosis of ventilator-associated pneumonia (VAP), compared with the use of 60 bronchoscopic protected specimen brushes (PSB) and 126 blinded plugged telescopic catheters (PTC) obtained from 134 patients. Gram stai...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/85.5.735

    authors: Mimoz O,Karim A,Mazoit JX,Edouard A,Leprince S,Nordmann P

    更新日期:2000-11-01 00:00:00

  • Prediction of outliers in pain, analgesia requirement, and recovery of function after childbirth: a prospective observational cohort study.

    abstract:BACKGROUND:Prediction models to identify parturients who experience protracted pain, prolonged opioid use, and delayed self-assessed functional recovery are currently inadequate. METHODS:For this study, 213 nulliparous women who planned vaginal delivery were enrolled and assessed daily until they completed three outco...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2018.04.033

    authors: Komatsu R,Carvalho B,Flood P

    更新日期:2018-08-01 00:00:00

  • Posture used by anaesthetists during laryngoscopy.

    abstract:BACKGROUND:There is little advice on the posture to be used when intubating the trachea. Does the stance used depend on experience? METHODS:Twenty-six subjects with varying experience of intubation were photographed during laryngoscopy of an intubation training mannequin. Posture was measured from the photographs and ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:

    authors: Walker JD

    更新日期:2002-11-01 00:00:00

  • Assessment of a scavenging device for use in paediatric anaesthesia.

    abstract::We describe a scavenging device, primarily for use during inhalation induction of anaesthesia in children; it was designed to optimize the often conflicting requirements of clinical acceptability and adequate gas collection. The performance was assessed in three ways. The device reduced the nitrous oxide concentration...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/64.1.117

    authors: Sik MJ,Lewis RB,Eveleigh DJ

    更新日期:1990-01-01 00:00:00

  • Use of neostigmine after snake bite.

    abstract::Cobra venom consists of a neurotoxin which is responsible for respiratory paralysis simulating that associated with a non-depolarizing muscle relaxant. A combination of artificial respiration and neostigmine has been useful in resuscitating a child bitten by a snake. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/49.10.1065

    authors: Naphade RW,Shetti RN

    更新日期:1977-10-01 00:00:00

  • Third-generation FloTrac/Vigileo does not reliably track changes in cardiac output induced by norepinephrine in critically ill patients.

    abstract:BACKGROUND:The ability of the third-generation FloTrac/Vigileo software to track changes in cardiac index (CI) induced by volume expansion and norepinephrine in critically ill patients is unknown. METHODS:In subjects with circulatory failure, we administered volume expansion (20 subjects) and increased (20 subjects) o...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer491

    authors: Monnet X,Anguel N,Jozwiak M,Richard C,Teboul JL

    更新日期:2012-04-01 00:00:00

  • Comparison of midwife top-ups, continuous infusion and patient-controlled epidural analgesia for maintaining mobility after a low-dose combined spinal-epidural.

    abstract::We studied 133 women given a combined spinal-epidural for analgesia in labour. The initial intrathecal dose contained bupivacaine 2.5 mg with fentanyl 25 micrograms. When the mothers were comfortable, they were allocated randomly to one of three groups: continuous infusion (group Cl, n = 46), midwife top-ups (group MW...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/82.2.233

    authors: Collis RE,Plaat FS,Morgan BM

    更新日期:1999-02-01 00:00:00

  • Medication safety in the operating room: literature and expert-based recommendations.

    abstract::Human error poses significant risk for hospitalized patients causing an estimated 100,000 to 400,000 deaths in the USA annually. Medication errors contribute, with error occurring in 5.3% of medication administrations during surgery. In this study 70.3% of medication errors were deemed preventable. Given the paucity o...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aew379

    authors: Wahr JA,Abernathy JH 3rd,Lazarra EH,Keebler JR,Wall MH,Lynch I,Wolfe R,Cooper RL

    更新日期:2017-01-01 00:00:00

  • Collaborative study of the frequency of the fluoride-resistant cholinesterase variant in patients with malignant hyperpyrexia.

    abstract::Cholinesterase phenotyping studies have been carried out in two laboratories on blood specimens from 28 patients shown to be susceptible to malignant hyperpyrexia. In contrast to previously published reports, no evidence could be found for an increase in the frequency of the E1u E1f genotype above that known to occur ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/53.3.245

    authors: Evans RT,Iqbal J,Ellis FR,Halsall PJ,Dietz AA,Lubrano T,Rubinstein HM

    更新日期:1981-03-01 00:00:00

  • Retraction notice to "Monitoring of neuromuscular block after administration of vecuronium in patients with diabetes mellitus" [Br J Anaesth 2003; 90: 480-486].

    abstract::This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Statistical analysis suggests t...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,撤回出版物

    doi:10.1016/j.bja.2018.11.007

    authors: Saitoh Y,Kaneda K,Hattori H,Nakajima H,Murakawa M

    更新日期:2019-01-01 00:00:00

  • Effect of ivabradine on major adverse cardiovascular events and mortality in critically ill patients: a systematic review and meta-analyses of randomised controlled trials with trial sequential analyses.

    abstract:BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.bja.2020.01.027

    authors: Chen A,Elia N,Dunaiceva J,Rudiger A,Walder B,Bollen Pinto B

    更新日期:2020-06-01 00:00:00

  • Cardiovascular effects of 50% nitrous oxide in older adult patients anaesthetized with isoflurane or halothane.

    abstract::We have studied the cardiovascular effects of equipotent concentrations of halothane or isoflurane, with or without 50% nitrous oxide in oxygen, in 80 patients, aged 60 yr or more, during 20 min of stable equipotent anaesthesia. Non-invasive measurement techniques were used, with suprasternal Doppler ultrasonography f...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/80.2.169

    authors: McKinney MS,Fee JP

    更新日期:1998-02-01 00:00:00

  • Preoperative intravenous iron before cardiac surgery: a prospective multicentre feasibility study.

    abstract:BACKGROUND:Preoperative anaemia affects one third of patients undergoing cardiac surgery and is associated with increased mortality and morbidity. Although it is recommended that perioperative teams should identify and treat patients with preoperative anaemia before surgery, introducing new treatment protocols can be c...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.bja.2019.11.023

    authors: Klein AA,Chau M,Yeates JA,Collier T,Evans C,Agarwal S,Richards T,UK Cardiac and Vascular Surgery Interventional Anaemia Response (CAVIAR) study team.

    更新日期:2020-03-01 00:00:00

  • Effect of interpleural morphine on postoperative pain and pulmonary function after thoracotomy.

    abstract::We have investigated the effect of interpleural morphine on postoperative pain and pulmonary function after thoracotomy. At the end of surgery, an interpleural catheter was inserted in 17 patients and, in a double-blind and randomized manner, either a bolus of morphine 2.5 mg interpleurally (i.p.) and normal saline i....

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/69.6.637

    authors: Welte M,Haimerl E,Groh J,Briegel J,Sunder-Plassmann L,Herz A,Peter K,Stein C

    更新日期:1992-12-01 00:00:00

  • Subarachnoid haemorrhage following spinal anaesthesia in an obstetric patient.

    abstract::We describe an obstetric patient who presented for removal of a retained placenta. After insertion of the spinal anaesthetic, she developed a severe headache, and a subarachnoid haemorrhage was diagnosed. We discuss the differential diagnosis of the headache, the occurrence of intracranial haemorrhages after dural pun...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/86.3.442

    authors: Eggert SM,Eggers KA

    更新日期:2001-03-01 00:00:00

  • Lack of effect of ketamine analgesia on gastric emptying in man.

    abstract::The effect of ketamine analgesia on gastric emptying was assessed in five healthy volunteers. Gastric emptying, estimated indirectly by the absorption of orally administered paracetamol, was not significantly delayed following administration of i.m. ketamine when compared with placebo. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/53.12.1321

    authors: Grant IS,Nimmo WS,Clements JA

    更新日期:1981-12-01 00:00:00

  • Gram stain of bronchoalveolar lavage fluid in the early diagnosis of ventilator-associated pneumonia.

    abstract::To assess the usefulness of the Gram stain in the early diagnosis of ventilator-associated pneumonia (VAP), we performed 146 protected specimen brushings (PSB) and bronchoalveolar lavages (BAL) in 118 patients suspected of having nosocomial pneumonia. Gram stain and counts of infected cells were performed in all sampl...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/83.6.845

    authors: Allaouchiche B,Jaumain H,Chassard D,Boulétreau P

    更新日期:1999-12-01 00:00:00

  • Temperature monitoring during general anaesthesia.

    abstract::A study of core temperature monitoring during general anesthesia indicates that this can be introduced as a routine procedure in order to reduce mortality from malignant hyperpyrexia. The temperature profiles of 2410 patients are presented. Both mean rectal and mean oesophageal temperatures decreased during general an...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/52.12.1223

    authors: Crocker BD,Okumura F,McCuaig DI,Denborough MA

    更新日期:1980-12-01 00:00:00

  • Pharmacokinetic and clinical study of ropivacaine and bupivacaine in women receiving extradural analgesia in labour.

    abstract::We have compared, in a randomized, double-blind study, the pharmacokinetics of ropivacaine and bupivacaine during labour. Total and free plasma concentrations of ropivacaine and bupivacaine were measured after the first of two extradural doses. The main dose was 20 mg (test dose) and 30 mg, with a top-up dose of 25 mg...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/79.5.558

    authors: McCrae AF,Westerling P,McClure JH

    更新日期:1997-11-01 00:00:00

  • Haemodynamic effects of vecuronium.

    abstract::Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/62.2.194

    authors: Wierda JM,Maestrone E,Bencini AF,Boyer A,Rashkovsky OM,Lip H,Karliczek R,Ket JM,Agoston S

    更新日期:1989-02-01 00:00:00

  • Periodic cardiovascular and ventilatory activity during midazolam sedation.

    abstract::We have examined the effects of sedation with midazolam 0.1 mg kg-1 and reversal with flumazenil 0.5 mg on beat-to-beat heart rate (HR) variability (HRV), systolic arterial pressure (SAP), finger photoplethysmograph amplitude (PLA) and impedence pneumography in eight volunteers. With the onset of sedation there was a ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/76.4.503

    authors: Galletly DC,Williams TB,Robinson BJ

    更新日期:1996-04-01 00:00:00

  • Isoflurane exerts antinociceptive and hypnotic properties at all ages in Fischer rats.

    abstract:BACKGROUND:Some anaesthetic agents exhibit an age-dependent analgesic effect, for example nitrous oxide, which is ineffective in newborn rats. We investigated whether a similar time dependency existed for the responses to the volatile anaesthetic isoflurane. METHODS:The analgesic and hypnotic properties of isoflurane ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aei182

    authors: Sanders RD,Patel N,Hossain M,Ma D,Maze M

    更新日期:2005-09-01 00:00:00

  • Haemodynamic effects of diaspirin crosslinked haemoglobin (DCLHb) given before abdominal aortic aneurysm surgery.

    abstract::We studied 34 patients undergoing elective repair of an abdominal aortic aneurysm under combined general anaesthesia and epidural block to evaluate the acute effects of diaspirin crosslinked haemoglobin (DCLHb) 50, 100 and 200 mg kg-1 i.v. Haemodynamic variables were measured continuously using pulmonary and radial ar...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/83.5.702

    authors: Garrioch MA,McClure JH,Wildsmith JA

    更新日期:1999-11-01 00:00:00

  • Isoflurane impairs odour discrimination learning in rats: differential effects on short- and long-term memory.

    abstract:BACKGROUND:Anaesthetics suppress the formation of lasting memories at concentrations that do not suppress perception, but it is unclear which elements of the complex cascade leading from a conscious experience to a lasting memory trace are disrupted. Experiments in conscious humans suggest that subhypnotic concentratio...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer451

    authors: Pearce RA,Duscher P,Van Dyke K,Lee M,Andrei AC,Perouansky M

    更新日期:2012-04-01 00:00:00

  • Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials.

    abstract::The relative analgesic efficacy and side-effect profile of peripheral nerve blockade (PNB) techniques compared with lumbar epidural analgesia for major knee surgery is unclear. We undertook a systematic review and meta-analysis of all randomized trials comparing epidural analgesia with PNB for major knee surgery. Eigh...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1093/bja/aem373

    authors: Fowler SJ,Symons J,Sabato S,Myles PS

    更新日期:2008-02-01 00:00:00

  • Pharmacokinetics of atracurium besylate in healthy patients (after a single i.v. bolus dose).

    abstract::The plasma decay of atracurium besylate was examined in two groups of six patients. Group I received atracurium 0.6 mg kg-1 and group II 0.3 mg kg-1 as a single bolus dose i.v. The plasma concentrations were measured by high performance liquid chromatography. An individual two-compartment pharmacokinetic model was use...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/55.2.113

    authors: Ward S,Neill EA,Weatherley BC,Corall IM

    更新日期:1983-02-01 00:00:00

  • Cardiac arrhythmia during outpatient dental anaesthesia: the advantages of a controlled ventilation technique.

    abstract::Two techniques for endotracheal anaesthesia in dental outpatients have been compared: a spontaneous ventilation technique using nitrous oxide, oxygen and halothane, and a controlled ventilation technique using nitrous oxide and oxygen, with tubocurarine and fentanyl. The latter technique has several advantages: abolit...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/48.9.919

    authors: Thomas VJ,Thomas WJ,Thurlow AC

    更新日期:1976-09-01 00:00:00