Increase in intragastric pressure during suxamethonium-induced muscle fasciculations in children: inhibition by alfentanil.

abstract：:We have investigated the incidence of regurgitation of gastric contents during general anaesthesia administered via a laryngeal mask airway (LMA) or face mask and Guedel airway in 56 patients with no risk factors for regurgitation. Patients swallowed a gelatin capsule containing methylene blue 10 min before induction ...

journal_title：British journal of anaesthesia

authors： Barker P,Langton JA,Murphy PJ,Rowbotham DJ

更新日期：1992-09-01 00:00:00

abstract：:The metabolic effect of infusing 1.0-1.5 litre of Hartmann's solution to normal subjects and those with maturity onset diabetes has been studied during surgery. It was found that the use of Hartmann's solution after operation was associated with a 7.5 mmol litre-u increase in plasm glucose concentration compared with ...

journal_title：British journal of anaesthesia

authors： Thomas DJ,Alberti KG

更新日期：1978-02-01 00:00:00

abstract：:An investigation was carried out into the relationship between the inflation pressures of normally compliant lungs and the airways pressure necessary to produce the insufflation of gas to the stomach. This relationship was examined during manual ventilation with a mask, using a rapid sequence induction technique. In t...

journal_title：British journal of anaesthesia

authors： Lawes EG,Campbell I,Mercer D

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for...

journal_title：British journal of anaesthesia

authors： Zuppa AF,Nicolson SC,Wilder NS,Ibla JC,Gottlieb EA,Burns KM,Stylianou M,Trachtenberg F,Ni H,Skeen TH,Andropoulos DB,Pediatric Heart Network Investigators.

更新日期：2019-12-01 00:00:00

abstract：:We have examined the role of benzodiazepine receptors in nitrous oxide-induced neuronal depression in rats. The changes in neuronal excitability induced by nitrous oxide and the benzodiazepine inverse agonist, Ro15-4513, were monitored by measurement of visual evoked potentials (VEP). Administration of Ro15-4513 10 mg...

journal_title：British journal of anaesthesia

authors： Dzoljic M,Erdmann W,Dzoljic MR

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Circadian variation may affect many biological and pharmacological phenomena. METHODS:To assess circadian variations in labour pain perception, 222 consecutive nulliparous women with uncomplicated pregnancy, spontaneous labour, cervical dilatation (3-5 cm), ruptured membranes and normal fetal heart rate tra...

journal_title：British journal of anaesthesia

authors： Aya AG,Vialles N,Mangin R,Robert C,Ferrer JM,Ripart J,de La Coussaye JE

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the prevalence of postoperative nausea and vomiting (PONV) after fast-track cardiac anaesthesia, risk factors for PONV and its influence on the length of stay in the intensive care unit (ICU). METHODS:A prospective study was performed in the cardiothoracic ICU (CTICU) ...

journal_title：British journal of anaesthesia

authors： Kogan A,Eidelman LA,Raanani E,Orlov B,Shenkin O,Vidne BA

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:The analgesia/nociception index (ANI), a 0-100 non-invasive index calculated from heart rate variability, reflects the analgesia/nociception balance during general anaesthesia. The aim of this study was to evaluate the ANI in the assessment of immediate postoperative pain in adult patients undergoing general...

journal_title：British journal of anaesthesia

authors： Boselli E,Daniela-Ionescu M,Bégou G,Bouvet L,Dabouz R,Magnin C,Allaouchiche B

更新日期：2013-09-01 00:00:00

abstract：:A double-blind randomized trial was conducted to compare etidocaine, the new local anaesthetic agent, with bupivacaine. One hundred patients were each given a single dose of one of the drugs during the surgical induction of labour. The results showed that etidocaine had a quicker onset of action than bupivacaine, but ...

journal_title：British journal of anaesthesia

authors： Phillips G

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Restrictive transfusion triggers are safe for most critically ill patients, but doubts exist for patients with ischaemic heart disease (IHD). We investigated the prevalence of reported IHD at admission to the intensive care unit (ICU) and investigated how this influenced red cell transfusion triggers. We als...

journal_title：British journal of anaesthesia

authors： Walsh TS,McClelland DB,Lee RJ,Garrioch M,Maciver CR,McArdle F,Crofts SL,Mellor I,ATICS Study Group.

更新日期：2005-04-01 00:00:00

abstract：:Thirty hypertensive patients scheduled for cholecystectomy or hernia repair under general anaesthesia with thiopentone-fentanyl-nitrous oxide-pancuronium were divided into two groups of 15. One group received metoprolol tablets 200 mg in a slow release form, once daily for at least 2 weeks including the morning of sur...

journal_title：British journal of anaesthesia

authors： Magnusson J,Thulin T,Werner O,Järhult J,Thomson D

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:The inhibitory effect of anaesthetic agents on hypoxic pulmonary vasoconstriction may depend upon their dose, especially when using a volatile agent. The aim of this randomized open study was to compare the effects of sevoflurane and propofol, as primary anaesthetic agents, on oxygenation during one-lung ven...

journal_title：British journal of anaesthesia

authors： Pruszkowski O,Dalibon N,Moutafis M,Jugan E,Law-Koune JD,Laloë PA,Fischler M

更新日期：2007-04-01 00:00:00

abstract：:Ketamine, as the sole anaesthetic agent, was assessed in a double-blind study of 135 female patients who underwent laparoscopic sterilization. The patients were allocated randomly to one of four groups according to the type (pentobarbitone or droperidol) and route (i.v. or i.m.) of premedication. In addition all the p...

journal_title：British journal of anaesthesia

authors： Figallo EM,Casali H,McKenzie R,Tantisira B,Wadhwa RK,Taylor FH

更新日期：1977-11-01 00:00:00

abstract：:We studied the elimination rate of nitrous oxide in 36 patients undergoing orthopaedic surgery. They were allocated randomly to one of six groups which differed in time of nitrous oxide exposure and mode of ventilation. In order to simulate recovery conditions, nitrous oxide administration was discontinued after 30, 6...

journal_title：British journal of anaesthesia

authors： Einarsson S,Stenqvist O,Bengtsson A,Houltz E,Bengtson JP

更新日期：1993-08-01 00:00:00

abstract：:The safety of aspirin therapy in neuraxial anaesthesia has been historically questioned, and the current recommendations are still heterogeneous. A comprehensive review of clinical evidence and a comparative analysis of European and American guidelines were performed. Low-dose aspirin produces a selective, complete an...

journal_title：British journal of anaesthesia

authors： Vela Vásquez RS,Peláez Romero R

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Intraperitoneal insufflation of carbon dioxide (CO2) may promote collapse of dependent lung regions. The present study was undertaken to study the effects of CO2-pneumoperitoneum (CO2-PP) on atelectasis formation, arterial oxygenation, and arterial to end-tidal PCO2-gradient (Pa-E'(CO2)). METHODS:Fifteen an...

journal_title：British journal of anaesthesia

authors： Strang CM,Hachenberg T,Fredén F,Hedenstierna G

更新日期：2009-08-01 00:00:00

abstract：:All currently available aminoacylaniline local anaesthetics, except lignocaine, contain a chiral centre but are used as racemates, a fact usually ignored in pharmacokinetic studies. This study reports the cardiovascular effects, and the regional and total body clearances of the enantiomers of bupivacaine determined at...

journal_title：British journal of anaesthesia

authors： Rutten AJ,Mather LE,McLean CF

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:The ProSeal laryngeal mask airway (PLMA) is a new laryngeal mask device with a modified cuff and a drainage tube. METHODS:We assessed the PLMA in 300 anaesthetized adults either paralysed or breathing spontaneously. We assessed insertion characteristics, airway seal pressures, haemodynamic response to inser...

journal_title：British journal of anaesthesia

authors： Evans NR,Gardner SV,James MF,King JA,Roux P,Bennett P,Nattrass R,Llewellyn R,Visu D

更新日期：2002-04-01 00:00:00

abstract：:We have used mivacurium in four myasthenic patients presenting for thymectomy. Supramaximal single twitch stimulation was applied to the ulnar nerve at the wrist and the force of contraction of the adductor pollicis was measured. After an initial bolus dose of 30 micrograms kg-1 (approximately one-fifth of the normal ...

journal_title：British journal of anaesthesia

authors： Paterson IG,Hood JR,Russell SH,Weston MD,Hirsch NP

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Abnormal serum sodium concentrations are common in patients presenting for surgery. It remains unclear whether these abnormalities are independent risk factors for postoperative mortality. METHODS:This is a secondary analysis of the European Surgical Outcome Study (EuSOS) that provided data describing 46 53...

journal_title：British journal of anaesthesia

authors： Cecconi M,Hochrieser H,Chew M,Grocott M,Hoeft A,Hoste A,Jammer I,Posch M,Metnitz P,Pelosi P,Moreno R,Pearse RM,Vincent JL,Rhodes A,European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society o

更新日期：2016-01-01 00:00:00

abstract：:We have examined the effects of two types of insulin therapy (continuous i.v. infusion (group A: 1.25 u. h-1) and direct i.v. bolus administration of 10 u. every 2 h (group B: 10 u./2 h)) on the metabolic and endocrine responses to surgery in 60 adult diabetic patients undergoing general anaesthesia for elective proce...

journal_title：British journal of anaesthesia

authors： Raucoules-Aime M,Ichai C,Roussel LJ,Romagnan MJ,Gastaud P,Dolisi C,Grimaud D

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:We investigated the effects of spinal and general anaesthesia and surgical tourniquet on acute pain and early recovery after total knee arthroplasty (TKA). METHODS:Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without...

journal_title：British journal of anaesthesia

authors： Palanne R,Rantasalo M,Vakkuri A,Madanat R,Olkkola KT,Lahtinen K,Reponen E,Linko R,Vahlberg T,Skants N

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Anaesthetics blunt neuronal responses to noxious stimulation, including effects on electroencephalographic (EEG) responses. It is unclear how anaesthetics differ in their ability to modulate noxious stimulation-evoked EEG activation. We investigated the actions of propofol and halothane on EEG responses to n...

journal_title：British journal of anaesthesia

authors： Orth M,Barter L,Dominguez C,Atherley R,Carstens E,Antognini JF

更新日期：2005-10-01 00:00:00

abstract：:To understand the cellular and molecular basis of the anaesthetic state, it is important to remember that, in the intact CNS, synapses operate within elaborate nerve networks. From the data presented above, it is evident that block of impulse conduction in presynaptic fibres does not explain the effects of most anesth...

journal_title：British journal of anaesthesia

authors： Pocock G,Richards CD

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Balloon dilatational tracheostomy using the Ciaglia Blue Dolphin device has recently been introduced as a modification of the Ciaglia technique. The aim of this study was to compare the new Dolphin system with the single-step dilatational tracheostomy (Ciaglia Blue Rhino) in intensive care unit (ICU) patient...

journal_title：British journal of anaesthesia

authors： Cianchi G,Zagli G,Bonizzoli M,Batacchi S,Cammelli R,Biondi S,Spina R,Peris A

更新日期：2010-06-01 00:00:00

abstract：:The pressor and catecholamine responses to laryngoscopy and intubation were studied in nine patients with pregnancy-induced hypertension (PIH) and in eight normotensive controls. Five of the PIH patients had received oral labetalol as antihypertensive therapy. Mean arterial pressure (MAP) increased significantly from ...

journal_title：British journal of anaesthesia

authors： Lavies NG,Meiklejohn BH,May AE,Achola KJ,Fell D

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Studies of the accuracy of partial rebreathing measurements of pulmonary blood flow (PBF) in patients with abnormal lungs have not fully explained the sources of error. METHODS:We used computer models of emphysema and pulmonary embolism incorporating both ventilation-perfusion (V/Q) and ventilation-volume (...

journal_title：British journal of anaesthesia

authors： Yem JS,Turner MJ,Baker AB

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which reflect spinal excitability, has been shown for propofol. We have assessed the concentration-dependent F-wave suppression by propofol and related it to th...

journal_title：British journal of anaesthesia

authors： Baars JH,Tas S,Herold KF,Hadzidiakos DA,Rehberg B

更新日期：2006-01-01 00:00:00

abstract：:We have investigated the effects of propofol on beat-to-beat fluctuations in heart rate, arterial pressure (continuous arterial tonometry) and infrared finger plethysmography in 10 healthy male patients undergoing elective surgery. Administration of Diprivan (propofol 10 mg ml-1) 0.2 ml kg-1, followed by an infusion o...

journal_title：British journal of anaesthesia

authors： Robinson BJ,Buyck HC,Galletly DC

更新日期：1994-08-01 00:00:00

abstract：:Infusion thrombophlebitis is a common complication of i.v. infusions. Many factors appear to be involved in its aetiology, of which the duration of infusion, the drugs infused and the solution(s) infused are the most important. Effective prophylaxis should be based on an understanding of the possible pathophysiology. ...

journal_title：British journal of anaesthesia

authors： Lewis GB,Hecker JF

更新日期：1985-02-01 00:00:00