Beneficial effects of statins on the microcirculation during sepsis: the role of nitric oxide.

abstract：BACKGROUND:Recent investigations showed that isoflurane can induce pharmacological preconditioning. The present study aimed to compare the potency of four different halogenated anaesthetics to induce preconditioning. METHODS:Anaesthetized open-chest rabbits underwent 30 min of coronary artery occlusion followed by 3 h...

journal_title：British journal of anaesthesia

authors： Piriou V,Chiari P,Lhuillier F,Bastien O,Loufoua J,Raisky O,David JS,Ovize M,Lehot JJ

更新日期：2002-09-01 00:00:00

abstract：:We conducted a prospective, randomized, double-blind study to compare analgesia obtained by wound infiltration using 29 ml of 0.25% bupivacaine alone, or with the addition of clonidine hydrochloride 150 micrograms. A third group received bupivacaine wound infiltration with clonidine 150 micrograms i.m. to control for ...

journal_title：British journal of anaesthesia

authors： Elliott S,Eckersall S,Fligelstone L,Jothilingam S

更新日期：1997-10-01 00:00:00

abstract：:The activity of a new i.v. anesthetic agent ICI 35 868, a compound unrelated to currently used barbiturate, eugenol or steroid agents, has been examined in a range of animal species. Some of the properties of ICI 35 868 resemble those of thiopentone in that it is a rapidly acting agent which produces anaesthesia of sh...

journal_title：British journal of anaesthesia

authors： Glen JB

更新日期：1980-08-01 00:00:00

abstract：:We have investigated the value of lower oesophageal contractility (LOC) in detecting awareness during anaesthesia in 20 human volunteer patients. LOC was measured either with subjects awake or after induction with propofol, during induction with propofol, and then as consciousness returned. Statistically significant c...

journal_title：British journal of anaesthesia

authors： Isaac PA,Rosen M

更新日期：1990-09-01 00:00:00

abstract：:The effect of gas leakage around an uncuffed tracheal tube on the performance of Heat and Moisture Exchangers (HME) was examined experimentally. Such leaks were shown to cause measurable decreases in the humidity output and efficiency of HME. The magnitude of the decrease in humidity output was shown to be dependent u...

journal_title：British journal of anaesthesia

authors： Tilling SE,Hayes B

更新日期：1987-09-01 00:00:00

abstract：:Riluzole modulates several transmitter systems which may be involved in nociception. Antinociceptive effects have been shown in animal studies, but there are no human data. Therefore, we have examined the acute analgesic effect of riluzole in a human model of inflammatory pain induced by a thermal injury on the distal...

journal_title：British journal of anaesthesia

authors： Hammer NA,Lillesø J,Pedersen JL,Kehlet H

更新日期：1999-05-01 00:00:00

abstract：:Placental transfer of 14C-dimethyltubocurarine (14C-dmtc) was studied during Caesarean section. Liquid scintillation counting was used for determination of 14C activity from the maternal and foetal blood samples. Paper chromatography was used to confirm the stability of 14C-dmtc. In all cases 14C-dmtc was able to cros...

journal_title：British journal of anaesthesia

authors： Kivalo I,Saarikoski S

更新日期：1976-03-01 00:00:00

abstract：:Intragastric pressure was measured in 20 patients before, and immediately after, the induction of anaesthesia with thiopentone. Intragastric pressure decreased in patients whose weights were the same as or less than expected, and increased in five of seven patients whose weights were greater than expected (P = 0.0013)...

journal_title：British journal of anaesthesia

authors： Drummond GB,Park GR

更新日期：1984-08-01 00:00:00

abstract：:Standard methods for accurate intraoperative measurement of neuromuscular block are either expensive or inconvenient and are not used widely. We have evaluated a new method of monitoring neuromuscular block using a low-frequency microphone. The method is based on the phenomenon of low-frequency sound emission by contr...

journal_title：British journal of anaesthesia

authors： Dascalu A,Geller E,Moalem Y,Manoah M,Enav S,Rudick Z

更新日期：1999-09-01 00:00:00

abstract：:Anaesthetic and sedative drugs transiently disrupt normal neural activity to facilitate healthcare procedures in children, but they can also cause long-term brain injury in experimental animal models. The US Food and Drug Administration (FDA) has recently advised that repeated or lengthy exposures to anaesthetic and s...

journal_title：British journal of anaesthesia

authors： O'Leary JD,Warner DO

更新日期：2017-09-01 00:00:00

abstract：:We have documented the changes in gas exchange, haemodynamic state and associated physiological variables which occurred after graft reperfusion in 20 patients undergoing uncomplicated orthotopic liver transplantation. Gas exchange was measured during constant ventilation using a metabolic monitor. After reperfusion, ...

journal_title：British journal of anaesthesia

authors： Walsh TS,Hopton P,Garden OJ,Lee A

更新日期：1998-09-01 00:00:00

abstract：:A technique of induction of anaesthesia using propanidid, lignocaine and suxamethonium is described, and the muscle fasciculations that follow it are shown to be significantly less than those accompanying induction with methohexitone and suxamethonium. ...

journal_title：British journal of anaesthesia

authors： Fry EN

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:Handover of anaesthesia patient care during surgery is common; however, its association with patient outcome is unclear. This systematic review aimed to assess the impact of anaesthesia handover during surgery on patient outcome. METHODS:All prospective and retrospective clinical studies specifically invest...

journal_title：British journal of anaesthesia

authors： Boet S,Djokhdem H,Leir SA,Théberge I,Mansour F,Etherington N

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The inhibitory effect of anaesthetic agents on hypoxic pulmonary vasoconstriction may depend upon their dose, especially when using a volatile agent. The aim of this randomized open study was to compare the effects of sevoflurane and propofol, as primary anaesthetic agents, on oxygenation during one-lung ven...

journal_title：British journal of anaesthesia

authors： Pruszkowski O,Dalibon N,Moutafis M,Jugan E,Law-Koune JD,Laloë PA,Fischler M

更新日期：2007-04-01 00:00:00

abstract：:We have compared the viability criteria of muscle bundles used in the in vitro contracture test for susceptibility to malignant hyperthermia (MH) in a group of 28 patients with various neuromuscular diseases (NMD) and 93 MH-related family patients. In the patients with NMD, this standard test gave one positive, six eq...

journal_title：British journal of anaesthesia

authors： Adnet PJ,Krivosic-Horber RM,Krivosic I,Haudecoeur G,Reyford HG,Adamantidis MM,Medahoui H

更新日期：1994-01-01 00:00:00

abstract：:In order to investigate the analgesic effect of timing of administration of ketorolac 10 mg i.v., we recorded patient-controlled use of diamorphine at 2, 4 and 12 h after abdominal hysterectomy. In a randomized, double-blind trial, 30 patients received ketorolac before skin incision and 28 after skin closure. A contro...

journal_title：British journal of anaesthesia

authors： Rogers JE,Fleming BG,Macintosh KC,Johnston B,Morgan-Hughes JO

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:A recent study showed that the noble gas helium induces early myocardial preconditioning. Cyclooxygenase-2 (COX-2) has been shown to be an important mediator in the signal transduction of late preconditioning. In the present study, we investigated whether helium induces late preconditioning in a concentratio...

journal_title：British journal of anaesthesia

authors： Huhn R,Heinen A,Weber NC,Hieber S,Hollmann MW,Schlack W,Preckel B

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Normalization of plasma fibrinogen levels may be associated with satisfactory haemostasis and reduced bleeding. The aim of this retrospective study was to assess fibrinogen recovery parameters after administration of fibrinogen concentrate (Haemocomplettan P) to patients with diffuse bleeding in cardiovascul...

journal_title：British journal of anaesthesia

authors： Solomon C,Pichlmaier U,Schoechl H,Hagl C,Raymondos K,Scheinichen D,Koppert W,Rahe-Meyer N

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Recent studies have concluded that i.v. dexamethasone can prolong the duration of peripheral nerve blockade. We hypothesized that a 4 mg dose would equally prolong the duration of psoas compartment blocks (PCBs) when compared with 8 mg, and that both doses would prolong the duration when compared with placeb...

journal_title：British journal of anaesthesia

authors： Turner JD,Dobson SW,Weller RS,Russell GB,Henshaw DS

更新日期：2018-02-01 00:00:00

abstract：:This study was designed to observe the effects of i.v. fluid infusion on uterine activity during normal labour in women receiving an extradural block. Thirty-four women in spontaneous labour at term gestation were allocated randomly and prospectively to one of three i.v. pre-extradural fluid load groups: group A, no f...

journal_title：British journal of anaesthesia

authors： Cheek TG,Samuels P,Miller F,Tobin M,Gutsche BB

更新日期：1996-11-01 00:00:00

abstract：:Atropine and glycopyrrolate were compared in a mixture with neostigmine for reversal of neuromuscular blockade in patients undergoing open heart surgery. In patients not receiving beta-blocking drugs, glycopyrrolate was shown to possess advantages over atropine in terms of a lower initial increase in heart rate, bette...

journal_title：British journal of anaesthesia

authors： Salem MG,Richardson JC,Meadows GA,Lamplugh G,Lai KM

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Pressure recording analytical method (PRAM) is a novel, arterial pulse contour-based method for measuring cardiac output (CO). Validation studies of PRAM in children are few, and have not assessed both absolute accuracy and ability to track changes in CO across a broad case mix. We aimed to compare CO as mea...

journal_title：British journal of anaesthesia

authors： Saxena R,Durward A,Puppala NK,Murdoch IA,Tibby SM

更新日期：2013-03-01 00:00:00

abstract：:In a double-blind, placebo-controlled three-way cross over study, the efficacy of Ro 15-1788 200 mg, a new benzodiazepine antagonist, in blocking the amnesic, cognitive, psychomotor and subjective effects of diazepam 20 mg, was investigated in a group of six healthy male volunteers. The amnesic effects of diazepam wer...

journal_title：British journal of anaesthesia

authors： O'Boyle C,Lambe R,Darragh A,Taffe W,Brick I,Kenny M

更新日期：1983-04-01 00:00:00

abstract：:A computer-controlled infusion of propofol designed to achieve a target blood concentration of propofol 3 microgram ml-1 was used to investigate the possibility of an interaction between propofol and fentanyl in 32 patients undergoing body surface surgery. In 16 patients who were not receiving a neuromuscular blocker ...

journal_title：British journal of anaesthesia

authors： Dixon J,Roberts FL,Tackley RM,Lewis GT,Connell H,Prys-Roberts C

更新日期：1990-02-01 00:00:00

abstract：:Progressive obstruction of an axillary vein following an axillary approach to brachial plexus blockade is described. At surgical exploration, the axillary vein was narrowed with an aneurysm of its wall. It is likely that, during the performance of the block, the needle penetrated the adventitia of the vein, causing a ...

journal_title：British journal of anaesthesia

authors： Restelli L,Pinciroli D,Conoscente F,Cammelli F

更新日期：1984-09-01 00:00:00

abstract：:The effect of pretreatment with suxamethonium, gallamine or pancuronium on suxamethonium-induced fasciculations and myalgia was studied in a controlled, randomized and double-blind clinical trial. Both fasciculations and myalgia were assessed on a four-point rating scale. There was no significant correlation between f...

journal_title：British journal of anaesthesia

authors： O'Sullivan EP,Williams NE,Calvey TN

更新日期：1988-03-01 00:00:00

abstract：:This case series presents 10 patients undergoing vascular surgery with asymptomatic elevated high-sensitivity troponin T concentrations, measured at outpatient clinic before surgery. Patients were included in the RAVE (Rotterdam Antiplatelet therapy in Vascular patiEnts) pilot study. All included patients underwent co...

journal_title：British journal of anaesthesia

authors： Mol KHJM,Hoeks SE,van Mieghem NM,Verhagen HJM,Boersma E,Stolker RJ,van Lier F

更新日期：2019-11-01 00:00:00

abstract：:In the postoperative period fifty-six healthy patients undergoing cholecystectomy or operations for duodenal ulcer, received, in a randomized order, i.m., "high-level" or "low-level" extradural morphine. Thirty-five per cent in the i.m. group, 33% in the high-level group and 50% in the low-level group suffered urinary...

journal_title：British journal of anaesthesia

authors： Petersen TK,Husted SE,Rybro L,Schurizek BA,Wernberg M

更新日期：1982-11-01 00:00:00

abstract：:The effect of the topical application of a lignocaine-prilocaine cream (EMLA) on the pain of venous cannulation was tested in a double-blind manner. Sixty boys and girls between the ages of 4 and 10 yr who were to undergo surgery participated in the study. No analgesic premedication was given and the venous cannulatio...

journal_title：British journal of anaesthesia

authors： Maunuksela EL,Korpela R

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...

journal_title：British journal of anaesthesia

authors： Marty AP,Schmelzer S,Thomasin RA,Braun J,Zalunardo MP,Spahn DR,Breckwoldt J

更新日期：2020-07-01 00:00:00