Recordings of, and an anatomical explanation for, false positive loss of resistance during lumbar extradural analgesia.

abstract：:The effect of the administration of propranolol 0.15 mg per kg body weight i.v. on the metabolic response to pelvic surgery was compared with results in similar patients who had not received propranolol. The only significant difference between the two groups was a lower plasma insulin concentration in the beta-blockad...

journal_title：British journal of anaesthesia

authors： Cooper GM,Paterson JL,Mashiter K,Hall GM

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Tetrodotoxin (TTX) is a powerful sodium channel blocker extracted from the puffer fish. The analgesic effects of TTX were investigated in different animal pain models. METHODS:Wistar rats were submitted to the formalin test and to partial ligation of the sciatic nerve (Seltzer's model). Swiss Webster mice w...

journal_title：British journal of anaesthesia

authors： Marcil J,Walczak JS,Guindon J,Ngoc AH,Lu S,Beaulieu P

更新日期：2006-06-01 00:00:00

abstract：:We report the case of a morbidly obese patient who developed rhabdomyolysis with acute renal failure, hepatic dysfunction, and an increase of cardiac troponin-1 after total knee arthroplasty. Postoperative rhabdomyolysis has a wide range of triggers and differential diagnoses that should be considered by the anaesthes...

journal_title：British journal of anaesthesia

authors： Karcher C,Dieterich HJ,Schroeder TH

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine is an α-2-receptor agonist which might be used as an additive to local anaesthetics for various regional anaesthetic techniques. We therefore designed this prospective, double-blinded, controlled volunteer study to investigate the effects of dexmedetomidine as an adjuvant to ropivacaine on pe...

journal_title：British journal of anaesthesia

authors： Marhofer D,Kettner SC,Marhofer P,Pils S,Weber M,Zeitlinger M

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Low-dose droperidol is suggested to be cost-effective in preventing nausea and vomiting after ambulatory surgery. This clinical study evaluated patient postural stability using a computerized force platform after an i.v. dose of droperidol 0.625 mg in outpatients undergoing gynaecological dilatation and cure...

journal_title：British journal of anaesthesia

authors： Song D,Chung F,Yogendran S,Wong J

更新日期：2002-06-01 00:00:00

abstract：:In theory, setting an infrared multi-gas analyser to measure a volatile anaesthetic different from that in the sampled gas mixture may cause interference with carbon dioxide and nitrous oxide readings. The theory was investigated during evaluation of the Dräger Cicero EM anaesthetic workstation for the Medical Devices...

journal_title：British journal of anaesthesia

authors： Wilkes AR,Mapleson WW

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Tobacco use interventions in surgical patients who smoke could benefit both their short-term outcome and long-term health. Anaesthesiologists and surgeons can play key roles in delivering these interventions. This study determined the practices, attitudes, and beliefs of these physicians regarding tobacco us...

journal_title：British journal of anaesthesia

authors： Kai T,Maki T,Takahashi S,Warner DO

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:High-dose glucocorticoid may reduce postsurgical pain and improve recovery. We hypothesized that 125 mg methylprednisolone (MP) would reduce time to meet functional discharge criteria after total hip arthroplasty (THA). METHODS:Forty-eight patients undergoing unilateral THA under spinal anaesthesia were con...

journal_title：British journal of anaesthesia

authors： Lunn TH,Andersen LØ,Kristensen BB,Husted H,Gaarn-Larsen L,Bandholm T,Ladelund S,Kehlet H

更新日期：2013-01-01 00:00:00

abstract：:Mean venous pressures were measured in 20 patients in whom a catheter, inserted via the external jugular vein, failed to pass centrally. The catheter used had a rounded end and two side holes. Pressures were measured with the patient's head in three different positions. The pressures were compared with the central ven...

journal_title：British journal of anaesthesia

authors： Shah MV,Swai EA,Latto IP

更新日期：1986-12-01 00:00:00

abstract：:We have examined the effects of the highly selective alpha 2-adrenoceptor agonist, dexmedetomidine, on noradrenaline release and cell firing in isolated, superfused slices of rat locus coeruleus. Dexmedetomidine decreased both noradrenaline release and cell firing rate in a concentration-dependent fashion, with an EC5...

journal_title：British journal of anaesthesia

authors： Jorm CM,Stamford JA

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:We investigated the effects of spinal and general anaesthesia and surgical tourniquet on acute pain and early recovery after total knee arthroplasty (TKA). METHODS:Patients (n=413) were randomised to four parallel groups: spinal anaesthesia with or without tourniquet, and general anaesthesia with or without...

journal_title：British journal of anaesthesia

authors： Palanne R,Rantasalo M,Vakkuri A,Madanat R,Olkkola KT,Lahtinen K,Reponen E,Linko R,Vahlberg T,Skants N

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Multiple studies have shown that cerebral tissue oxygen saturation (Sct(O(2))) is decreased after phenylephrine treatment. We hypothesized that the negative impact of phenylephrine administration on Sct(O(2)) is affected by arterial blood carbon dioxide partial pressure (Pa(CO(2))) because CO(2) is a powerfu...

journal_title：British journal of anaesthesia

authors： Meng L,Gelb AW,Alexander BS,Cerussi AE,Tromberg BJ,Yu Z,Mantulin WW

更新日期：2012-05-01 00:00:00

abstract：:Before the induction of labour in 34 pregnant women 1.5% lignocaine 10 ml was injected into the lumbar extradural space at constant rates between 0.143 and 0.333 ml s-1. Injection pressures and residual pressures were recorded and the extent of analgesia to pinprick was assessed. No significant correlation was found b...

journal_title：British journal of anaesthesia

authors： Husemeyer RP,White DC

更新日期：1980-01-01 00:00:00

abstract：:The rate of gastric emptying in pregnancy was measured indirectly using the rate of paracetamol absorption in four groups of 15 patients: non-pregnant controls, first trimester patients presenting for termination of pregnancy, second trimester patients presenting for prostaglandin termination of pregnancy, and patient...

journal_title：British journal of anaesthesia

authors： Macfie AG,Magides AD,Richmond MN,Reilly CS

更新日期：1991-07-01 00:00:00

abstract：:We have compared the postoperative morphine requirements and analgesic efficacy of four doses of i.m. ketorolac 30 mg administered 6-hourly with placebo in a double-blind study of patients undergoing major or minor orthopaedic surgery. During the 24-h postoperative study period which began at the end of surgery, patie...

journal_title：British journal of anaesthesia

authors： Kinsella J,Moffat AC,Patrick JA,Prentice JW,McArdle CS,Kenny GN

更新日期：1992-07-01 00:00:00

abstract：:We have studied the effects of alfentanil administered intrathecally on somatosympathetic reflexes evoked by stimulation of radial and tibial nerves in 10 anaesthetized and paralysed dogs. In five animals, alfentanil was administered in doses of 100, 100, 200 and 400 micrograms in 0.8 ml and 800 micrograms in 1.6 ml p...

journal_title：British journal of anaesthesia

authors： Wang C,Chakrabarti MK,Whitwam JG

更新日期：1992-05-01 00:00:00

abstract：:Arterial blood and expired gas samples were taken from 20 patients before operation and on the first day after upper abdominal surgery. After operation the patients were studied breathing air and also breathing 35% oxygen from a venturi-type mask. Preoperative Pao2 with age was exaggerated by operation. Pao2 after ope...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1975-04-01 00:00:00

abstract：:Experiments were performed on rats using two analgesimetric tests (tail-flick; hot-plate) before and after injection i.v. of graded doses of aprotinin (12.5, 25.0 and 50 KIU g-1). A dose-related analgesic effect was noted with both tests. Prior administration of naloxone 0.001 mg g-1 i.p. inhibited the analgesic actio...

journal_title：British journal of anaesthesia

authors： Novelli GP,Pieraccioli E,Peduto VA,Festimanni F

更新日期：1980-11-01 00:00:00

abstract：:To determine if improved postoperative recovery in surgical inpatients receiving intraoperative therapeutic suggestions are applicable in an outpatient population, 70 consenting, unpremedicated adults undergoing elective outpatient hernia repair under general anaesthesia were allocated randomly to either a therapeutic...

journal_title：British journal of anaesthesia

authors： Lebovits AH,Twersky R,McEwan B

更新日期：1999-06-01 00:00:00

abstract：:We have compared the efficacy of adding varying concentrations of hyaluronidase to a standard mixture of 2% lidocaine and 1% ropivacaine to provide peribulbar anaesthesia for cataract surgery. We used (i) the time to adequate anaesthesia for surgery and (ii) ocular and eyelid movement scores at 8 min after block as cl...

journal_title：British journal of anaesthesia

authors： Mantovani C,Bryant AE,Nicholson G

更新日期：2001-06-01 00:00:00

abstract：:The effect of the combination of opiates and hypnotics on bispectral index (BIS) is unclear. This double-blind placebo-controlled trial investigated the effect on BIS and sedation of different infusion doses of remifentanil combined with a steady infusion of propofol. Forty patients initially received a target-control...

journal_title：British journal of anaesthesia

authors： Strachan AN,Edwards ND

更新日期：2000-04-01 00:00:00

abstract：:We describe a six-compartment physiological model of the kinetics and dynamics of induction of anaesthesia with propofol in sheep. It includes a faithful description of initial bolus kinetics caused by accurate representations of the inter-relationships between initial vascular mixing, lung kinetics and cardiac output...

journal_title：British journal of anaesthesia

authors： Upton RN,Ludbrook GL

更新日期：1997-10-01 00:00:00

abstract：:Lung function and clinical evidence of muscle weakness were assessed in 12 ASA I patients who received vecuronium 0.01 mg kg-1 pretreatment as a part of their anaesthetic management, before and 3 min after pretreatment. Most patients demonstrated ptosis and diplopia, while five of the 12 were unable to raise the head ...

journal_title：British journal of anaesthesia

authors： Mahajan RP,Laverty J

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Double-lumen tubes (DLTs) are frequently used to establish one-lung ventilation (OLV). Their correct placement is crucial. We hypothesized that electrical impedance tomography (EIT) reliably displays distribution of ventilation between left and right lung and may thus be used to verify correct DLT placement ...

journal_title：British journal of anaesthesia

authors： Steinmann D,Stahl CA,Minner J,Schumann S,Loop T,Kirschbaum A,Priebe HJ,Guttmann J

更新日期：2008-09-01 00:00:00

abstract：:Skills related to driving, the ability to discriminate the fusion of flickering light, and hand and foot proprioception, were measured double-blind in 34 healthy volunteers before and after three doses of i.v. diazepam. The effects of diazepam were most harmful to co-ordination. With 0.15 mg/kg, 0.30 mg/kg and 0.45 mg...

journal_title：British journal of anaesthesia

authors： Korttila K,Linnoila M

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:There has been increasing use of invasive techniques, such as extracorporeal organ support, in intensive care units (ICU), and declining autopsy rates. Thus, new measures are needed to maintain high-quality standards. We investigated the potential of computed tomography (CT)-based virtual autopsy to substitu...

journal_title：British journal of anaesthesia

authors： Wichmann D,Heinemann A,Zähler S,Vogel H,Höpker W,Püschel K,Kluge S

更新日期：2018-06-01 00:00:00

abstract：:By analysing the EEG, reticular multi-unit activity and behavioural changes, we have classified general anaesthetics into three groups: central nervous system (CNS) depressant, CNS excitant and epileptogenic agents. Changes in CNS neural activity are associated with alteration in transmitter release. We have attempted...

journal_title：British journal of anaesthesia

authors： Shichino T,Murakawa M,Adachi T,Arai T,Miyazaki Y,Mori K

更新日期：1998-03-01 00:00:00

abstract：:In our daily anaesthetic practice, we are confronted with an increasing number of patients treated with either antiplatelet or anticoagulant agents. During the last decade, changes have occurred that make the handling of antithrombotic medication a challenging part of anaesthetic perioperative management. In this revi...

journal_title：British journal of anaesthesia

authors： Koenig-Oberhuber V,Filipovic M

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Increasing numbers of older patients prescribed clopidogrel are presenting for urgent hip fracture surgery. Best practice for the management of clopidogrel therapy is unknown, although delays to surgery are associated with increased mortality. We investigated the influence of perioperative management of clop...

journal_title：British journal of anaesthesia

authors： Collyer TC,Reynolds HC,Truyens E,Kilshaw L,Corcoran T

更新日期：2011-12-01 00:00:00

abstract：:The influence of sodium nitroprusside (SNP) on mitochondrial respiration was examined in rat liver mitochondria. The addition of SNP 1 mmol litre-1 during state 3 respiration inhibited the oxygen uptake by 63.4%. A mixture of SNP 1 mmol litre-1 and glutathione (GSH) 1 mmol litre-1 inhibited the oxygen uptake more mark...

journal_title：British journal of anaesthesia

authors： Nakamura S,Shin T,Hirokata Y,Shigematsu A

更新日期：1977-12-01 00:00:00