A physiological model of induction of anaesthesia with propofol in sheep. 1. Structure and estimation of variables.

abstract：BACKGROUND:The analgesic efficacy of continuous transversus abdominis plane (TAP) blocks in comparison with that of single-injection TAP blocks is not clear. This randomized, triple-blind, placebo-controlled trial investigated the benefits of adding continuous TAP blocks to single-injection TAP blocks after a laparotom...

journal_title：British journal of anaesthesia

authors： Yoshida T,Furutani K,Watanabe Y,Ohashi N,Baba H

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Data on bupivacaine concentrations in the cerebral spinal fluid (CSF) during spinal anaesthesia are scarce. The purpose of this study was to determine the concentration of bupivacaine in the lumbar CSF of patients with an adequate level of spinal anaesthesia after injection of plain bupivacaine 0.5%. METHOD...

journal_title：British journal of anaesthesia

authors： Ruppen W,Steiner LA,Drewe J,Hauenstein L,Brugger S,Seeberger MD

更新日期：2009-06-01 00:00:00

abstract：:We randomized women having elective Caesarean section to receive either no preload (control group, n=33) or 4% gelatin solution (Gelofusine) 15 ml kg(-1) (colloid group, n=35) i.v. before spinal anaesthesia. Intravenous metaraminol was titrated at 0.25-0.75 mg min(-1) to maintain systolic arterial pressure (SAP) in th...

journal_title：British journal of anaesthesia

authors： Ngan Kee WD,Khaw KS,Lee BB,Ng FF,Wong MM

更新日期：2001-11-01 00:00:00

abstract：:In obstetric patients undergoing postpartum tubal ligation, we found that metoclopramide produced dose-dependent prolongation of suxamethonium-induced neuromuscular block. Mean block times after suxamethonium 1 mg kg-1 were 8.0 min, 9.83 min and 12.45 min for control and metoclopramide 10 mg and metoclopramide 20 mg g...

journal_title：British journal of anaesthesia

authors： Kao YJ,Tellez J,Turner DR

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:The objective of the present study was to investigate the effects of increasing doses of norepinephrine (NE) with or without arginine-vasopressin (AVP) on intestinal oxygen supply and jejunal mucosal tissue oxygen tension in an acute endotoxic pig model. METHODS:In this prospective, randomized, experimental...

journal_title：British journal of anaesthesia

authors： Maier S,Hasibeder W,Pajk W,Hengl C,Ulmer H,Hausdorfer H,Wurzinger B,Knotzer H

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Descriptions of the pharmacokinetics and metabolism of morphine and its metabolites in young children are scant. Previous studies have not differentiated the effects of size from those related to age during infancy. METHODS:Postoperative children 0-3 yr old were given an intravenous loading dose of morphine...

journal_title：British journal of anaesthesia

authors： Bouwmeester NJ,Anderson BJ,Tibboel D,Holford NH

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Anaesthetic preconditioning (A_PreC) and postconditioning (A_PostC) both provide protection against ischaemia-reperfusion in the heart. However, post-ischaemic gene responses may differ between the two therapeutic strategies. METHODS:Isolated perfused rat hearts were exposed to 40 min test ischaemia followe...

journal_title：British journal of anaesthesia

authors： Lucchinetti E,da Silva R,Pasch T,Schaub MC,Zaugg M

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...

journal_title：British journal of anaesthesia

authors： Marty AP,Schmelzer S,Thomasin RA,Braun J,Zalunardo MP,Spahn DR,Breckwoldt J

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:One-lung ventilation (OLV) increases mechanical stress in the lung and affects ventilation and perfusion (V, Q). There are no data on the effects of OLV on postoperative V/Q matching. Thus, this controlled study evaluates the influence of OLV on V/Q distribution in a pig model using a gamma camera technique ...

journal_title：British journal of anaesthesia

authors： Kozian A,Schilling T,Fredén F,Maripuu E,Röcken C,Strang C,Hachenberg T,Hedenstierna G

更新日期：2008-04-01 00:00:00

abstract：:Two techniques for endotracheal anaesthesia in dental outpatients have been compared: a spontaneous ventilation technique using nitrous oxide, oxygen and halothane, and a controlled ventilation technique using nitrous oxide and oxygen, with tubocurarine and fentanyl. The latter technique has several advantages: abolit...

journal_title：British journal of anaesthesia

authors： Thomas VJ,Thomas WJ,Thurlow AC

更新日期：1976-09-01 00:00:00

abstract：:Transoesophageal echocardiography (TOE) is valuable for perioperative monitoring in patients at risk from haemodynamic disturbance. However, its use is not practicable in patients undergoing surgical procedures under regional anaesthesia. We describe two cases showing that transthoracic echocardiography (TTE) has the ...

journal_title：British journal of anaesthesia

authors： Filipovic M,Seeberger MD,Schneider MC,Schmid M,Pargger H,Hunziker P,Skarvan K

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Patient dissatisfaction has been previously associated with motor block in shoulder surgery patients receiving brachial plexus block. For elective minor wrist and hand surgery, we tested whether a regional block accelerating the early return of upper extremity motor function would improve patient satisfactio...

journal_title：British journal of anaesthesia

authors： Fredrickson MJ,Wolstencroft PJ,Chinchanwala S,Boland MR

更新日期：2012-11-01 00:00:00

abstract：:We have compared deep body temperature (DBT) measured at the forehead with the core temperatures of the nasopharynx, oesophagus and rectum during the warming phase of cardiopulmonary bypass (CPB) (moderate hypothermia of 26.7-29.6 degrees C) in 12 patients. DBT was measured transcutaneously by an insulated thermistor ...

journal_title：British journal of anaesthesia

authors： Sakuragi T,Mukai M,Dan K

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine has been proposed as a perineural local anaesthetic (LA) adjunct to prolong peripheral nerve block duration; however, results from our previous meta-analysis in the setting of brachial plexus block (BPB) did not support its use. Many additional randomized trials have since been published. We ...

journal_title：British journal of anaesthesia

authors： Vorobeichik L,Brull R,Abdallah FW

更新日期：2017-02-01 00:00:00

abstract：:Nociceptin/orphanin FQ, N/OFQ, and its receptor NOP represent a non-opioid branch of the opioid superfamily that were first studied for their effects on pain responses. Both N/OFQ and NOP are involved in a wide range of 'non-pain' responses including immunomodulation and cardiovascular control. There is now growing in...

journal_title：British journal of anaesthesia

authors： Serrano-Gomez A,Thompson JP,Lambert DG

更新日期：2011-01-01 00:00:00

abstract：:The pressor and catecholamine responses to laryngoscopy and intubation were studied in nine patients with pregnancy-induced hypertension (PIH) and in eight normotensive controls. Five of the PIH patients had received oral labetalol as antihypertensive therapy. Mean arterial pressure (MAP) increased significantly from ...

journal_title：British journal of anaesthesia

authors： Lavies NG,Meiklejohn BH,May AE,Achola KJ,Fell D

更新日期：1989-10-01 00:00:00

abstract：:We describe the performance of the pneuPAC hyperbaric variant HB, a ventilator designed for use in a one-man hyperbaric chamber. The ventilator delivered minute volumes of 11-23 litre at 1 atm abs to 7.6-16 litre at 2.5 atm abs. The delivered minute volume may be controlled easily from outside the chamber by manipulat...

journal_title：British journal of anaesthesia

authors： Spittal MJ,Hunter SJ,Jones L

更新日期：1991-10-01 00:00:00

abstract：:Arterial blood and expired gas samples were taken from 20 patients before operation and on the first day after upper abdominal surgery. After operation the patients were studied breathing air and also breathing 35% oxygen from a venturi-type mask. Preoperative Pao2 with age was exaggerated by operation. Pao2 after ope...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1975-04-01 00:00:00

abstract：:Cancer treatment is associated with significant morbidity and mortality. Surgery is a mainstay of treatment for many tumours, and anaesthetists care for cancer patients on a daily basis. Surgery itself induces a stress response and inhibits the immune system, and cancer surgery is associated with the release of tumour...

journal_title：British journal of anaesthesia

authors： Tedore T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Opioids can increase sensitivity to noxious stimuli and cause opioid-induced hyperalgesia. We performed a systematic review to evaluate the clinical consequences of intra-operative doses of opioid. METHODS:We identified randomized controlled trials which compared intra-operative opioid to lower doses or pla...

journal_title：British journal of anaesthesia

authors： Fletcher D,Martinez V

更新日期：2014-06-01 00:00:00

abstract：:We have compared bispectral index (BIS), 95% spectral edge frequency (SEF) and approximate entropy (ApEn) in 37 patients during induction and recovery from a short general anaesthetic. Heart rate variability (HRV) was also compared during induction only. These indices were noted at the start of induction, when a syrin...

journal_title：British journal of anaesthesia

authors： Sleigh JW,Donovan J

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Tetrodotoxin (TTX) is a powerful sodium channel blocker extracted from the puffer fish. The analgesic effects of TTX were investigated in different animal pain models. METHODS:Wistar rats were submitted to the formalin test and to partial ligation of the sciatic nerve (Seltzer's model). Swiss Webster mice w...

journal_title：British journal of anaesthesia

authors： Marcil J,Walczak JS,Guindon J,Ngoc AH,Lu S,Beaulieu P

更新日期：2006-06-01 00:00:00

abstract：Background:Cognitive aids improve the technical performance of individuals and teams dealing with high-stakes crises. Hand-held electronic cognitive aids have rarely been investigated. A randomized controlled trial was conducted to investigate the effects of a smartphone application, named MAX (for Medical Assistance e...

journal_title：British journal of anaesthesia

authors： Lelaidier R,Balança B,Boet S,Faure A,Lilot M,Lecomte F,Lehot JJ,Rimmelé T,Cejka JC

更新日期：2017-11-01 00:00:00

abstract：:In our daily anaesthetic practice, we are confronted with an increasing number of patients treated with either antiplatelet or anticoagulant agents. During the last decade, changes have occurred that make the handling of antithrombotic medication a challenging part of anaesthetic perioperative management. In this revi...

journal_title：British journal of anaesthesia

authors： Koenig-Oberhuber V,Filipovic M

更新日期：2016-09-01 00:00:00

abstract：:Isolated, cultured rat pancreatic islets of Langerhans were incubated in medium containing glucose 2 or 20 mmol litre-1 and with glucose supplemented with midazolam 10, 100 or 1000 ng ml-1. Glucose 20 mmol litre-1 with the addition of noradrenaline 10 mumol litre-1 was used as a control. In contrast with noradrenaline...

journal_title：British journal of anaesthesia

authors： Desborough JP,Jones PM,Persaud SJ,Howell SL

更新日期：1993-02-01 00:00:00

abstract：:Thirty hypertensive patients scheduled for cholecystectomy or hernia repair under general anaesthesia with thiopentone-fentanyl-nitrous oxide-pancuronium were divided into two groups of 15. One group received metoprolol tablets 200 mg in a slow release form, once daily for at least 2 weeks including the morning of sur...

journal_title：British journal of anaesthesia

authors： Magnusson J,Thulin T,Werner O,Järhult J,Thomson D

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:The current prevalence of healthcare-associated infections (HCAIs) is a major public health concern. Patient contact in the operating theatre (OT) can contribute to HCAI via microbial contamination. The application of hand hygiene is effective in reducing infection rates. Limited data are available on adhere...

journal_title：British journal of anaesthesia

authors： Krediet AC,Kalkman CJ,Bonten MJ,Gigengack AC,Barach P

更新日期：2011-10-01 00:00:00

abstract：:We have studied post-tetanic count (PTC) and single twitch height at the onset of reflex movement to carinal stimulation after administration of vecuronium with five different types of anaesthesia. Seventy-five adult patients were allocated randomly to five groups of 15 patients each, to receive one of the following a...

journal_title：British journal of anaesthesia

authors： Saitoh Y,Kaneda K,Toyooka H,Amaha K

更新日期：1994-06-01 00:00:00

abstract：:The plasma decay of atracurium besylate was examined in two groups of six patients. Group I received atracurium 0.6 mg kg-1 and group II 0.3 mg kg-1 as a single bolus dose i.v. The plasma concentrations were measured by high performance liquid chromatography. An individual two-compartment pharmacokinetic model was use...

journal_title：British journal of anaesthesia

authors： Ward S,Neill EA,Weatherley BC,Corall IM

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:The use of lipid emulsions to reduce cardiac toxicity of local anaesthetics (LAs) has shown success in experimental studies and some clinical cases, and thus has been implemented in clinical practice. However, lipid treatment is usually given after the occurrence of neurological or cardiovascular symptoms of...

journal_title：British journal of anaesthesia

authors： Aumeier C,Kasdorf B,Gruber M,Busse H,Wiese CH,Zink W,Graf BM,Zausig YA

更新日期：2014-04-01 00:00:00