Effects of midazolam on insulin secretion from isolated rat pancreatic islets of Langerhans.

abstract：:Two groups of six patients were studied during light general anaesthesia using 2% enflurane and 66% nitrous oxide in oxygen, combined with regional anaesthesia, for hernia and varicose vein surgery. The effects of 3% enflurane were compared with those of fentanyl 0.3 microgram kg-1 i.v., by measuring inspired flow, ti...

journal_title：British journal of anaesthesia

authors： Drummond GB

更新日期：1983-09-01 00:00:00

abstract：:We have compared, in a randomized study in 26 patients, immediate and late postoperative recovery after elective laparoscopic cholecystectomy using the gasless, mechanical abdominal wall lift method with conventional carbon dioxide pneumoperitoneum. After the gasless method, tracheal extubation was performed significa...

journal_title：British journal of anaesthesia

authors： Koivusalo AM,Kellokumpu I,Lindgren L

更新日期：1996-11-01 00:00:00

abstract：:Critical narrowing of the dependent airways was examined in anaesthetized dogs with closed chests. Two techniques were used, (a) "closing" volume (CV), measured from the expired nitrogen plateau and (b) tantalum bronchography, to measure the calibre of airways of 3-8 mm diameter in the upper (UZ), middle (MZ) and lowe...

journal_title：British journal of anaesthesia

authors： Jones JG,Graf PD,Lemen R

更新日期：1978-08-01 00:00:00

abstract：:It is known that propofol can have effects on atrioventricular node conduction. We report a case where administration of propofol was associated with termination of supraventricular tachycardia. Although a similar phenomenon has been reported in children, this is the first such case in an adult. ...

journal_title：British journal of anaesthesia

authors： Kannan S,Sherwood N

更新日期：2002-06-01 00:00:00

abstract：INTRODUCTION:In the context of an increasing number of publications of trial data analysed by Bayesian methods, clinicians need support to better understand Bayesian statistical methods. The existing checklists are intended for people who already know these methods. We aimed to establish and validate a checklist that c...

journal_title：British journal of anaesthesia

authors： Ferreira D,Barthoulot M,Pottecher J,Torp KD,Diemunsch P,Meyer N

更新日期：2020-08-01 00:00:00

abstract：:In 40 patients anaesthetized with thiopentone, 66% nitrous oxide and 1% halothane, the effects of a single i.v. dose of nalbuphine 4.5, 8, 15, 25 or 50 mg/70 kg or morphine 3, 5, 10 or 17.5 mg/70 kg on total ventilation and end-tidal carbon dioxide concentration have been measured. Depression of respiration occurred w...

journal_title：British journal of anaesthesia

authors： Klepper ID,Rosen M,Vickers MD,Mapleson WW

更新日期：1986-06-01 00:00:00

abstract：:The effects of ventilation with 30% and 100% oxygen were investigated on the circulatory and electrocardiographic response to electroconvulsive therapy (ECT) in 12 patients during 40 treatments. Administration of 30% oxygen resulted in a 25% decrease in seizure duration compared with 100% oxygen (P less than 0.0125). ...

journal_title：British journal of anaesthesia

authors： Räsänen J,Martin DJ,Downs JB,Hodges MR

更新日期：1988-11-01 00:00:00

abstract：:In vitro experiments on the rat phrenic nerve-hemidiaphragm preparation, stimulated directly or indirectly with supramaximal impulses at 0.1 Hz revealed that pethidine in concentrations greater than 5 micrograms ml-1 caused a rapid increase of the twitch. This was maximal (60% increase during direct and 70% increase d...

journal_title：British journal of anaesthesia

authors： Boros M,Chaudhry IA,Nagashima H,Duncalf RM,Sherman EH,Foldes FF

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:Interscalene brachial plexus block (ISBPB) is an effective nerve block for shoulder surgery. However, a 100% incidence of phrenic nerve palsy limits the application of ISBPB for patients with limited pulmonary reserve. We examined the incidence of phrenic nerve palsy with a low-volume ISBPB compared with a s...

journal_title：British journal of anaesthesia

authors： Riazi S,Carmichael N,Awad I,Holtby RM,McCartney CJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...

journal_title：British journal of anaesthesia

authors： Chen A,Elia N,Dunaiceva J,Rudiger A,Walder B,Bollen Pinto B

更新日期：2020-06-01 00:00:00

abstract：:The activity of a new i.v. anesthetic agent ICI 35 868, a compound unrelated to currently used barbiturate, eugenol or steroid agents, has been examined in a range of animal species. Some of the properties of ICI 35 868 resemble those of thiopentone in that it is a rapidly acting agent which produces anaesthesia of sh...

journal_title：British journal of anaesthesia

authors： Glen JB

更新日期：1980-08-01 00:00:00

abstract：:The majority of patients with acute respiratory distress syndrome (ARDS) require mechanical ventilation. This support provides time for the lungs to heal, but the adverse effects of mechanical ventilation significantly influence patient outcome. Traditionally, these were ascribed to mechanical effects, such as haemody...

journal_title：British journal of anaesthesia

authors： Moloney ED,Griffiths MJ

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:There are no studies comparing local anaesthetic requirements for obese and normal parturients. Obesity has been associated with a higher incidence of Caesarean section and higher levels of epidural block have also been found in obese obstetric patients, suggesting they may require less local anaesthetic. Th...

journal_title：British journal of anaesthesia

authors： Panni MK,Columb MO

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Myocardial potassium channels are complexes formed by different subunits. The subunit composition may influence the cardiotoxic action of local anaesthetics. The effects of amide local anaesthetics on HERG channels co-expressed with the putative subunit MiRP1 have not been established. It is also unclear if ...

journal_title：British journal of anaesthesia

authors： Friederich P,Solth A,Schillemeit S,Isbrandt D

更新日期：2004-01-01 00:00:00

abstract：:We have determined the influence of 0.1 minimum alveolar concentration (MAC) of sevoflurane on ventilation, the acute ventilatory response to a step change in end-tidal carbon dioxide and the ventilatory response to sustained hypercapnia in 10 healthy adult volunteers. Subjects undertook a preliminary 10-min period of...

journal_title：British journal of anaesthesia

authors： Pandit JJ,Manning-Fox J,Dorrington KL,Robbins PA

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:The cuff pressures may be different in oesophageal and tracheal intubations. We conducted a study to evaluate if cuff pressures of endotracheal tubes (ETTs) could provide information to distinguish tracheal or oesophageal intubations in a pig trachea-oesophagus model. METHODS:In each preparation of pig trac...

journal_title：British journal of anaesthesia

authors： Lin HJ,Chen KT,Foo NP,Hsu CC,Guo HR

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:This study compares cardiac output (CO) measurements obtained by lithium dilution (LiDCO), pulse power analysis (PulseCO), and continuous thermodilution (CTD) with bolus thermodilution (BTD) in ponies. METHODS:Eight isoflurane-anaesthetized Shetland ponies received xylazine, ketamine, and midazolam infusion...

journal_title：British journal of anaesthesia

authors： Ambrisko TD,Coppens P,Kabes R,Moens Y

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Pulse pressure variation (PPV) and stroke volume variation (SVV) are robust indicators of fluid responsiveness in mechanically ventilated supine patients. The aim of the study was to evaluate the ability of PPV and SVV to predict fluid responsiveness in mechanically ventilated patients in the prone position ...

journal_title：British journal of anaesthesia

authors： Biais M,Bernard O,Ha JC,Degryse C,Sztark F

更新日期：2010-04-01 00:00:00

abstract：:The use of atracurium in 25 patients undergoing general surgical procedures is described, neuromuscular function being monitored by the "train-of-four" stimuli. An initial dose of atracurium 0.5 mg kg-1 proved to be clinically acceptable, giving good conditions for endotracheal intubation and adequate muscle relaxatio...

journal_title：British journal of anaesthesia

authors： Hunter JM,Jones RS,Utting JE

更新日期：1982-12-01 00:00:00

abstract：:This was a prospective, non-randomized, multicentre study of rocuronium (Org 9426) in 40 elective Caesarean section patients at full term without fetal distress. Anaesthesia was induced with thiopentone 4-6 mg kg-1 i.v. and rocuronium 0.6 mg kg-1 and maintained with isoflurane and nitrous oxide in oxygen. Monitors inc...

journal_title：British journal of anaesthesia

authors： Abouleish E,Abboud T,Lechevalier T,Zhu J,Chalian A,Alford K

更新日期：1994-09-01 00:00:00

abstract：Background.:Perioperative administration of cefazolin reduces the incidence of perioperative infections. Intraoperative re-dosing of cefazolin is commonly given between 2 and 5 h after the initial dose. This study was undertaken to determine whether intraoperative continuous infusions of cefazolin achieve better probab...

journal_title：British journal of anaesthesia

authors： Naik BI,Roger C,Ikeda K,Todorovic MS,Wallis SC,Lipman J,Roberts JA

更新日期：2017-06-01 00:00:00

abstract：:The effects of bolus doses of phenoperidine 1-2 mg i.v. either alone, or combined with pancuronium 2-4 mg, were investigated in seven patients in traumatic coma. Phenoperidine alone significantly reduced mean arterial pressure (MAP) by a mean (+/- SEM) of 13.2 (+/- 2.8) mm Hg. Overall there was no significant change i...

journal_title：British journal of anaesthesia

authors： Bingham RM,Hinds CJ

更新日期：1987-05-01 00:00:00

abstract：:Chronic pain affects ∼20% of the European population and is commoner in women, older people, and with relative deprivation. Its management in the community remains generally unsatisfactory, partly because of lack of evidence for effective interventions. Epidemiological study of chronic pain, through an understanding o...

journal_title：British journal of anaesthesia

authors： van Hecke O,Torrance N,Smith BH

更新日期：2013-07-01 00:00:00

abstract：:A disposable patient-controlled analgesia (PCA) device was evaluated in 20 children after major abdominal, urological and orthopaedic surgery. All patients were given a high dependency level of nursing care in general wards. Efficacy (as assessed by hourly pain scores) was comparable to that achieved in a matched cont...

journal_title：British journal of anaesthesia

authors： Irwin M,Gillespie JA,Morton NS

更新日期：1992-04-01 00:00:00

abstract：:We have used the technique of double-blind sequential allocation to quantify the minimum local analgesic concentration (MLAC) of extradural bupivacaine for women in early (median cervical dilatation 2 cm) and late (median cervical dilatation 5 cm) labour. The first bolus was 20 ml of the bupivacaine test solution. The...

journal_title：British journal of anaesthesia

authors： Capogna G,Celleno D,Lyons G,Columb M,Fusco P

更新日期：1998-01-01 00:00:00

abstract：:Anaesthetic and sedative drugs transiently disrupt normal neural activity to facilitate healthcare procedures in children, but they can also cause long-term brain injury in experimental animal models. The US Food and Drug Administration (FDA) has recently advised that repeated or lengthy exposures to anaesthetic and s...

journal_title：British journal of anaesthesia

authors： O'Leary JD,Warner DO

更新日期：2017-09-01 00:00:00

abstract：:To assess the effect of sevoflurane anaesthesia on hepatocellular integrity, we measured plasma concentrations of glutathione S-transferase (GST) before anaesthesia and 1, 3, 6 and 24 h after the end of anaesthesia in 41 healthy, Japanese patients undergoing elective, body surface surgery. Sevoflurane (approximately 1...

journal_title：British journal of anaesthesia

authors： Ray DC,Bomont R,Mizushima A,Kugimiya T,Forbes Howie A,Beckett GJ

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:Clinicians frequently warn patients of discomfort before potentially painful procedures, despite the lack of evidence that such communications are helpful. We aimed to compare two communications (one with, and the other without, a warning of a 'sting') immediately before i.v. cannulation in order to measure ...

journal_title：British journal of anaesthesia

authors： Dutt-Gupta J,Bown T,Cyna AM

更新日期：2007-12-01 00:00:00

abstract：:Thirteen of 31 Belgian Landrace pigs developed malignant hyperthermia (MH) after breathing halothane. A short period of exercise 1 h before the administration of the triggering agent increased the incidence of the syndrome to 100% in eight similar pigs. Clinical symptoms were more marked and developed more rapidly in ...

journal_title：British journal of anaesthesia

authors： van den Hende C,Lister D,Muylle E,Ooms L,Oyaert W

更新日期：1976-09-01 00:00:00

abstract：:This case report outlines the clinical process whereby a patient with severe traumatic brain injury became a non-heartbeating organ donor after a withdrawal-of-care decision. This process raises a series of ethical questions regarding decision-making on grounds of futility, the role of the next of kin, informed consen...

journal_title：British journal of anaesthesia

authors： Bell MD

更新日期：2005-04-01 00:00:00