Leukemia inhibitory factor (LIF) potentiates antinociception activity and inhibits tolerance induction of opioids.

abstract：BACKGROUND:This study aimed to investigate whether reversal of rocuronium-induced neuromuscular blockade with sugammadex reduced the incidence of residual blockade and facilitated operating room discharge readiness. METHODS:Adult patients undergoing abdominal surgery received rocuronium, followed by randomized allocat...

journal_title：British journal of anaesthesia

authors： Brueckmann B,Sasaki N,Grobara P,Li MK,Woo T,de Bie J,Maktabi M,Lee J,Kwo J,Pino R,Sabouri AS,McGovern F,Staehr-Rye AK,Eikermann M

更新日期：2015-11-01 00:00:00

abstract：:The effect of incubation at 37 degrees C, 46 degrees C, 47 degrees C and 48 degrees C for 1 h on the osmotic fragility of blood was determined. Blood taken from volunteers into ACD and CPD was examined after 1, 7, 14 and 21 days of storage. In addition, 22-day-old blood stored in CPD was examined. The osmotic fragilit...

journal_title：British journal of anaesthesia

authors： Van der Walt JH,Russell WJ

更新日期：1978-08-01 00:00:00

abstract：:In an open study we have investigated the efficacy of 20 ml of 0.75% ropivacaine (7.5 mg ml-1) to provide extradural anaesthesia for elective Caesarean section. Plasma concentrations (total and free) were estimated in the mother and neonate. Anaesthesia was effective and safe. Plasma concentrations of ropivacaine in t...

journal_title：British journal of anaesthesia

authors： Morton CP,Bloomfield S,Magnusson A,Jozwiak H,McClure JH

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Anaesthesia and surgery are associated with impairment of the immune system expressed as an excessive proinflammatory immune response and suppression of cell-mediated immunity that may affect the course of the postoperative period. Addition of anaesthetic agents capable of attenuating the alterations in peri...

journal_title：British journal of anaesthesia

authors： Beilin B,Rusabrov Y,Shapira Y,Roytblat L,Greemberg L,Yardeni IZ,Bessler H

更新日期：2007-10-01 00:00:00

abstract：:This article briefly reviews psychological aspects of pain, paying special attention to chronic pain. The review considers the interruptive and interference effects of pain and its impact on a person's identity. The importance of processes related to interruption, interference, and identity will vary across people and...

journal_title：British journal of anaesthesia

authors： Morley S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Single-lung ventilation in infants and small children is challenging because suitable sizes of double-lumen cuffed tracheal tubes are not available. A 6-yr-old child required pulmonary saline washout for primary alveolar proteinosis, and therefore needed sequential single-lung ventilation in order to achieve...

journal_title：British journal of anaesthesia

authors： Wilson CA,Arthurs OJ,Black AE,Schievano S,Hunt C,van Hoog S,Wallis C,Sury MR

更新日期：2015-10-01 00:00:00

abstract：:Percutaneous tracheostomy is being used increasingly in the intensive care unit and endoscopic control of this procedure affords an improved level of safety. Training in such new minimal access techniques can be a significant risk factor in patient outcome. Surgical simulation provides training which minimizes this ri...

journal_title：British journal of anaesthesia

authors： Gardiner Q,White PS,Carson D,Shearer A,Frizelle F,Dunkley P

更新日期：1998-09-01 00:00:00

abstract：:The case histories are reported of one patient who developed evidence of extradural infection 16 days postpartum, and another who spontaneously developed an extradural haematoma. Several points of interest and concern raised by these case histories are discussed. ...

journal_title：British journal of anaesthesia

authors： Crawford JS

更新日期：1975-03-01 00:00:00

abstract：:Isolated, cultured rat pancreatic islets of Langerhans were incubated in medium containing glucose 2 or 20 mmol litre-1 and with glucose supplemented with midazolam 10, 100 or 1000 ng ml-1. Glucose 20 mmol litre-1 with the addition of noradrenaline 10 mumol litre-1 was used as a control. In contrast with noradrenaline...

journal_title：British journal of anaesthesia

authors： Desborough JP,Jones PM,Persaud SJ,Howell SL

更新日期：1993-02-01 00:00:00

abstract：:Atropine and glycopyrronium are frequently used for premedication to reduce oral and respiratory secretions and prevent bradycardia. Glycopyrronium is said to have similar antisialagogue effects, but is less likely to cause significant tachycardia than atropine. Different antimuscarinic receptor selectivity patterns c...

journal_title：British journal of anaesthesia

authors： Gomez A,Bellido I,Sanchez de la Cuesta F

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Whether exposure to a single general anaesthetic (GA) in early childhood causes long-term neurodevelopmental problems remains unclear. METHODS:PubMed/MEDLINE, Embase, CINAHL, Web of Science, and the Cochrane Library were searched from inception to October 2019. Studies evaluating neurodevelopmental outcomes...

journal_title：British journal of anaesthesia

authors： Ing C,Jackson WM,Zaccariello MJ,Goldberg TE,McCann ME,Grobler A,Davidson A,Sun L,Li G,Warner DO

更新日期：2021-02-01 00:00:00

abstract：Background:The influence of different head and neck positions on the effectiveness of ventilation with the air-Q® self-pressurizing airway remains unevaluated. This study aimed to evaluate the influence of different head and neck positions on ventilation with the air-Q® SP airway. Methods:In this prospective, randomiz...

journal_title：British journal of anaesthesia

authors： Kim HJ,Lee K,Bai S,Kim MH,Oh E,Yoo YC

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The purpose of this prospective study was to assess the blood-sparing effect, the quality of analgesia, and the incidence of side-effects of a low-dose regime of intrathecal opioids (ITO) when compared with those of a high-dose regime in scoliosis surgery in children. METHODS:Forty-six children were randoml...

journal_title：British journal of anaesthesia

authors： Eschertzhuber S,Hohlrieder M,Keller C,Oswald E,Kuehbacher G,Innerhofer P

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...

journal_title：British journal of anaesthesia

authors： Chen A,Elia N,Dunaiceva J,Rudiger A,Walder B,Bollen Pinto B

更新日期：2020-06-01 00:00:00

abstract：:Cancer treatment is associated with significant morbidity and mortality. Surgery is a mainstay of treatment for many tumours, and anaesthetists care for cancer patients on a daily basis. Surgery itself induces a stress response and inhibits the immune system, and cancer surgery is associated with the release of tumour...

journal_title：British journal of anaesthesia

authors： Tedore T

更新日期：2015-12-01 00:00:00

abstract：:We have developed a simple, reliable method for rapid analysis of the partial pressure of volatile anaesthetic agents, based on a two-stage, head-space analysis. It is designed to solve the problems associated with reduced solubility of modern anaesthetics. After equilibration and analysis of a 2-ml sample of blood at...

journal_title：British journal of anaesthesia

authors： Smith MA,Sapsed-Byrne SM,Lockwood GG

更新日期：1997-04-01 00:00:00

abstract：:Methodology for assessment of depth of anaesthesia based on analysis of the electroencephalogram (EEG) is controversial. Techniques range from display of single measures, for example median value of the frequency spectrum, to dedicated pattern recognition systems based on measures of several EEG features. We have comp...

journal_title：British journal of anaesthesia

authors： Thomsen CE,Prior PF

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Better education of clinicians is expected to enhance patient safety. An important component of education is adherence to standard protocols, which are mainly available in written form. Believing in the potential power of videos, we hypothesized that the introduction of an educational video, based on an inst...

journal_title：British journal of anaesthesia

authors： Kandler L,Tscholl DW,Kolbe M,Seifert B,Spahn DR,Noethiger CB

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The current prevalence of healthcare-associated infections (HCAIs) is a major public health concern. Patient contact in the operating theatre (OT) can contribute to HCAI via microbial contamination. The application of hand hygiene is effective in reducing infection rates. Limited data are available on adhere...

journal_title：British journal of anaesthesia

authors： Krediet AC,Kalkman CJ,Bonten MJ,Gigengack AC,Barach P

更新日期：2011-10-01 00:00:00

abstract：:We randomized women having elective Caesarean section to receive either no preload (control group, n=33) or 4% gelatin solution (Gelofusine) 15 ml kg(-1) (colloid group, n=35) i.v. before spinal anaesthesia. Intravenous metaraminol was titrated at 0.25-0.75 mg min(-1) to maintain systolic arterial pressure (SAP) in th...

journal_title：British journal of anaesthesia

authors： Ngan Kee WD,Khaw KS,Lee BB,Ng FF,Wong MM

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Recent investigations showed that isoflurane can induce pharmacological preconditioning. The present study aimed to compare the potency of four different halogenated anaesthetics to induce preconditioning. METHODS:Anaesthetized open-chest rabbits underwent 30 min of coronary artery occlusion followed by 3 h...

journal_title：British journal of anaesthesia

authors： Piriou V,Chiari P,Lhuillier F,Bastien O,Loufoua J,Raisky O,David JS,Ovize M,Lehot JJ

更新日期：2002-09-01 00:00:00

abstract：:The value of the continuous monitoring of end-tidal carbon dioxide concentration as an indicator of the acute intraoperative interruption of pulmonary blood flow, in patients with pre-existing restrictions of pulmonary blood flow undergoing closed heart surgery, is illustrated by two case reports. Decreases in end-tid...

journal_title：British journal of anaesthesia

authors： Schuller JL,Bovill JG,Nijveld A

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Patients undergoing non-cardiac, non-vascular surgery are at risk of major cardiovascular complications. In non-cardiac surgery, troponin elevation has previously been shown to be an independent predictor of major adverse cardiac events and postoperative mortality; however, a majority of studies have focused...

journal_title：British journal of anaesthesia

authors： Ekeloef S,Alamili M,Devereaux PJ,Gögenur I

更新日期：2016-11-01 00:00:00

abstract：:Conventional extradural analgesia during labour with 0.25-0.375% bupivacaine may induce motor weakness and subjective sensory deficit, reducing maternal satisfaction. Even in a regimen for ambulatory extradural analgesia (0.1% bupivacaine-fentanyl 2 micrograms ml-1), a potential for proprioreception impairment exists,...

journal_title：British journal of anaesthesia

authors： Buggy DJ,MacDowell C

更新日期：1996-02-01 00:00:00

abstract：:The determination of blood flow, i.e. cardiac output, is an integral part of haemodynamic monitoring. This is a review on noninvasive continuous cardiac output monitoring in perioperative and intensive care medicine. We present the underlying principles and validation data of the following technologies: thoracic elect...

journal_title：British journal of anaesthesia

authors： Saugel B,Cecconi M,Wagner JY,Reuter DA

更新日期：2015-04-01 00:00:00

abstract：:One hundred patients presenting for surgical treatment of fractured neck of femur were allocated to receive either spinal (SAB) or general (GA) anaesthesia. Before operation, the mean PaO2 was 9.04 kPa. There was a significant decrease in PaO2 of 0.68 kPa in GA group at 1 h after operation, while blood-gas values were...

journal_title：British journal of anaesthesia

authors： McKenzie PJ,Wishart HY,Dewar KM,Gray I,Smith G

更新日期：1980-01-01 00:00:00

abstract：:Thirteen of 31 Belgian Landrace pigs developed malignant hyperthermia (MH) after breathing halothane. A short period of exercise 1 h before the administration of the triggering agent increased the incidence of the syndrome to 100% in eight similar pigs. Clinical symptoms were more marked and developed more rapidly in ...

journal_title：British journal of anaesthesia

authors： van den Hende C,Lister D,Muylle E,Ooms L,Oyaert W

更新日期：1976-09-01 00:00:00

abstract：:We studied 325 patients undergoing elective noncardiac surgery who had preoperative ambulatory ECG monitoring performed for a duration of 5130 h (range 8-24 h; mean 15.8 h). Sixty-four subjects (20%) had one or more episodes of ST segment depression consistent with myocardial ischaemia. Of all preoperative cardiovascu...

journal_title：British journal of anaesthesia

authors： Allman KG,Muir A,Howell SJ,Hemming AE,Sear JW,Foëx P

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Tapentadol is an analgesic agent for treatment of acute and chronic pain that activates the µ-opioid receptor combined with inhibition of neuronal norepinephrine reuptake. Both mechanisms are implicated in activation of descending inhibitory pain pathways. In this study, we investigated the influence of tape...

journal_title：British journal of anaesthesia

authors： Niesters M,Proto PL,Aarts L,Sarton EY,Drewes AM,Dahan A

更新日期：2014-07-01 00:00:00

abstract：:This case report outlines the clinical process whereby a patient with severe traumatic brain injury became a non-heartbeating organ donor after a withdrawal-of-care decision. This process raises a series of ethical questions regarding decision-making on grounds of futility, the role of the next of kin, informed consen...

journal_title：British journal of anaesthesia

authors： Bell MD

更新日期：2005-04-01 00:00:00