Ropivacaine 0.75% for extradural anaesthesia in elective caesarean section: an open clinical and pharmacokinetic study in mother and neonate.

Abstract:

:In an open study we have investigated the efficacy of 20 ml of 0.75% ropivacaine (7.5 mg ml-1) to provide extradural anaesthesia for elective Caesarean section. Plasma concentrations (total and free) were estimated in the mother and neonate. Anaesthesia was effective and safe. Plasma concentrations of ropivacaine in the mother and neonate were within safe limits and consistent with previous studies. Two mothers received accidental i.v. injections of ropivacaine 75 mg and 150 mg, respectively, without serious adverse effects.

journal_name

Br J Anaesth

authors

Morton CP,Bloomfield S,Magnusson A,Jozwiak H,McClure JH

doi

10.1093/bja/79.1.3

subject

Has Abstract

pub_date

1997-07-01 00:00:00

pages

3-8

issue

1

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)39895-1

journal_volume

79

pub_type

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