Quantitative EEG in assessment of anaesthetic depth: comparative study of methodology.

abstract：:Using in vivo microdialysis, we have investigated the effects of propofol on acetylcholine (ACh) release from various regions of the rat brain. Propofol 25 and 50 mg kg-1 i.p. decreased basal ACh release from the frontal cortex by 70% and 85%, respectively. Propofol 25 and 50 mg kg-1 i.p. decreased basal ACh release f...

journal_title：British journal of anaesthesia

authors： Kikuchi T,Wang Y,Sato K,Okumura F

更新日期：1998-05-01 00:00:00

abstract：:We have measured the onset and extent of the miotic effect of morphine and alfentanil in conscious patients. Forty unpremedicated ASA I and II patients were allocated randomly to four groups to receive either i.v. saline (control group), morphine 0.1 mg kg-1, alfentanil 4.0 micrograms kg-1 or a combination of these do...

journal_title：British journal of anaesthesia

authors： Miller CD,Asbury AJ,Brown JH

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The aim of this study was to explore difficulties at work from anaesthetists' own perspective and to examine how anaesthetists handle and cope with situations that are perceived as difficult and potentially stressful. METHODS:Two sets of interviews were conducted with 19 specialist anaesthetists in Sweden. ...

journal_title：British journal of anaesthesia

authors： Larsson J,Rosenqvist U,Holmström I

更新日期：2007-10-01 00:00:00

abstract：:Recommendations for resuscitation of patients in early haemorrhagic shock, with active ongoing bleeding, have evolved in recent years. This review covers current theories of the pathophysiology of shock and recommended treatments, including damage control surgery, deliberate hypotensive management, administration of a...

journal_title：British journal of anaesthesia

authors： Dutton RP

更新日期：2012-12-01 00:00:00

abstract：:In this study, we simultaneously evaluated the spasmolytic effects of prostaglandin E1 (PGE1) on serotonin-induced bronchoconstriction and pulmonary hypertension. Eleven mongrel dogs (8-12 kg) anaesthetized with pentobarbital were assigned to two groups: saline (n = 4) and PGE1 (n = 7). Bronchoconstriction and pulmona...

journal_title：British journal of anaesthesia

authors： Hashimoto Y,Hirota K,Yoshioka H,Hashiba E,Kudo T,Ishihara H,Matsuki A

更新日期：2000-09-01 00:00:00

abstract：:We have examined the role of gamma-aminobutyric acid (GABA) neurones in propofol anaesthesia in mice using the righting reflex. Propofol i.p. increased the percentage of loss of the righting reflex in a dose-dependent manner with an ED50 value of 140 (95% confidence limits 123-160) mg kg-1 (n = 40; eight animals per d...

journal_title：British journal of anaesthesia

authors： Irifune M,Sugimura M,Takarada T,Maeoka K,Shimizu Y,Dohi T,Nishikawa T,Kawahara M

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Anaesthetics suppress the formation of lasting memories at concentrations that do not suppress perception, but it is unclear which elements of the complex cascade leading from a conscious experience to a lasting memory trace are disrupted. Experiments in conscious humans suggest that subhypnotic concentratio...

journal_title：British journal of anaesthesia

authors： Pearce RA,Duscher P,Van Dyke K,Lee M,Andrei AC,Perouansky M

更新日期：2012-04-01 00:00:00

abstract：:Blood samples were obtained from a radial artery cannula in a 60-yr-old man during coronary artery surgery. Serum potassium concentrations of 9.3, 8.4, and 7.4 mmol litre(-1) were obtained. A simultaneous venous blood sample gave a serum potassium concentration of 4.4 mmol litre(-1). The ECG was unchanged. After the a...

journal_title：British journal of anaesthesia

authors： Mehta V,Ahmed Z

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:One-lung ventilation (OLV) increases mechanical stress in the lung and affects ventilation and perfusion (V, Q). There are no data on the effects of OLV on postoperative V/Q matching. Thus, this controlled study evaluates the influence of OLV on V/Q distribution in a pig model using a gamma camera technique ...

journal_title：British journal of anaesthesia

authors： Kozian A,Schilling T,Fredén F,Maripuu E,Röcken C,Strang C,Hachenberg T,Hedenstierna G

更新日期：2008-04-01 00:00:00

abstract：:Using an airway management training model, we have assessed anaesthesia personnel in their use of correct cricoid force and ability to retain this skill after a short training programme. A perspex device, working on a hydraulic principle, was used to measure cricoid pressure when applied to the model. After initial as...

journal_title：British journal of anaesthesia

authors： Ashurst N,Rout CC,Rocke DA,Gouws E

更新日期：1996-10-01 00:00:00

abstract：:Interest in the use of psychosocial interventions to help older adults manage pain is growing. In this article, we review this approach. The first section reviews the conceptual background for psychosocial interventions with a special emphasis on the biopsychosocial model of pain. The second section highlights three p...

journal_title：British journal of anaesthesia

authors： Keefe FJ,Porter L,Somers T,Shelby R,Wren AV

更新日期：2013-07-01 00:00:00

abstract：:In clinical use, the concentrations of local anaesthetics at the site of action are unknown. With the method described here, concentrations of local anaesthetics can be predetermined and kept constant at the site of action. In six volunteers, a blister was raised on the ventral surface of the forearm. After removal of...

journal_title：British journal of anaesthesia

authors： Wiesemes R,Klement W,Novotny GE,Lipfert P

更新日期：1993-05-01 00:00:00

abstract：:The effect of the combination of opiates and hypnotics on bispectral index (BIS) is unclear. This double-blind placebo-controlled trial investigated the effect on BIS and sedation of different infusion doses of remifentanil combined with a steady infusion of propofol. Forty patients initially received a target-control...

journal_title：British journal of anaesthesia

authors： Strachan AN,Edwards ND

更新日期：2000-04-01 00:00:00

abstract：:Riluzole modulates several transmitter systems which may be involved in nociception. Antinociceptive effects have been shown in animal studies, but there are no human data. Therefore, we have examined the acute analgesic effect of riluzole in a human model of inflammatory pain induced by a thermal injury on the distal...

journal_title：British journal of anaesthesia

authors： Hammer NA,Lillesø J,Pedersen JL,Kehlet H

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:The ability of the third-generation FloTrac/Vigileo software to track changes in cardiac index (CI) induced by volume expansion and norepinephrine in critically ill patients is unknown. METHODS:In subjects with circulatory failure, we administered volume expansion (20 subjects) and increased (20 subjects) o...

journal_title：British journal of anaesthesia

authors： Monnet X,Anguel N,Jozwiak M,Richard C,Teboul JL

更新日期：2012-04-01 00:00:00

abstract：:Bupivacaine is used widely as a local anaesthetic but has potential for severe cardiovascular and central nervous system (CNS) toxicity. It has an asymmetric carbon atom giving it a chiral centre, and the commercial preparation is a racemic mixture of its two enantiomers: dextro or R(+)-bupivacaine and levo or S(-)-bu...

journal_title：British journal of anaesthesia

authors： Cox CR,Checketts MR,Mackenzie N,Scott NB,Bannister J

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the ci...

journal_title：British journal of anaesthesia

authors： Gögenur I,Wildschiøtz G,Rosenberg J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Handover of anaesthesia patient care during surgery is common; however, its association with patient outcome is unclear. This systematic review aimed to assess the impact of anaesthesia handover during surgery on patient outcome. METHODS:All prospective and retrospective clinical studies specifically invest...

journal_title：British journal of anaesthesia

authors： Boet S,Djokhdem H,Leir SA,Théberge I,Mansour F,Etherington N

更新日期：2020-10-01 00:00:00

abstract：:We studied 100 healthy women undergoing outpatient gynaecological laparoscopy in a randomized, double-blind and placebo-controlled study to evaluate the effect of neostigmine on postoperative nausea and vomiting (PONV). After induction of anaesthesia with propofol, anaesthesia was maintained with sevoflurane and 66% n...

journal_title：British journal of anaesthesia

authors： Nelskylä K,Yli-Hankala A,Soikkeli A,Korttila K

更新日期：1998-11-01 00:00:00

abstract：:Both the performance of breathing systems and recommendations for the fresh gas flows to be used in patients breathing spontaneously can be expressed in ml kg-1 min-1 or fresh gas: total ventilation ratio (VF:VE). We have examined the relationship between these two descriptions. The data of 106 subjects (awake volunte...

journal_title：British journal of anaesthesia

authors： Soni N,Ooi R

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The observation that patients presenting for bariatric surgery had a high incidence of neuromuscular blocking agent (NMBA) anaphylaxis prompted this restricted case-control study to test the hypothesis that obesity is a risk factor for NMBA anaphylaxis, independent of differences in pholcodine consumption. ...

journal_title：British journal of anaesthesia

authors： Sadleir PHM,Clarke RC,Goddard CE,Day C,Weightman W,Middleditch A,Platt PR

更新日期：2021-01-13 00:00:00

abstract：:A combination of exogenous surfactant and partial liquid ventilation (PLV) with perfluorocarbons should enhance gas exchange, improve respiratory mechanics and reduce tissue damage of the lung in acute lung injury (ALI). We used a small dose of exogenous surfactant with and without PLV in an experimental model of ALI ...

journal_title：British journal of anaesthesia

authors： Wolf S,Lohbrunner H,Busch T,Sterner-Kock A,Deja M,Sarrafzadeh A,Neumann U,Kaisers U

更新日期：2001-10-01 00:00:00

abstract：:We have studied the efficacy of i.v. clonidine to suppress post-extradural shivering in parturients. Forty healthy parturients who received extradural block for labour (n = 20) or for Caesarean section (n = 20) and who required treatment for shivering after delivery were allocated randomly to two groups. Group I recei...

journal_title：British journal of anaesthesia

authors： Capogna G,Celleno D

更新日期：1993-08-01 00:00:00

abstract：:One explanation for diminished opioid analgesic efficacy is opioid-induced hyperalgesia (OIH). We report a case of OIH in an infant with gastroschisis, requiring multiple surgical interventions and prolonged sedation for ventilation. This is the first report of OIH in an infant. On day 41 of life after nine separate s...

journal_title：British journal of anaesthesia

authors： Hallett BR,Chalkiadis GA

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Pressures (Pe) exerted by bronchial blockers on the inner wall of the bronchi may cause mucosal ischaemia. Our aims were as follows: (i) to compare the intracuff pressure (Pi) and Pe exerted by commercially available bronchial blockers in an in vitro and an ex vivo model; (ii) to investigate the influence of...

journal_title：British journal of anaesthesia

authors： Carassiti M,Mattei A,Pizzo CM,Vallone N,Saccomandi P,Schena E

更新日期：2016-09-01 00:00:00

abstract：:Volume loading with crystalloid solution results in more pronounced haemodilution in patients who develop arterial hypotension during induction of extradural anaesthesia than in those who remain normotensive. The aim of this study was to describe the time course of this increase in haemodilution. Heart rate, systolic ...

journal_title：British journal of anaesthesia

authors： Drobin D,Hahn RG

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:The Alaris AEP monitor(TM) (Alaris, UK, version 1.4) is the first commercially available auditory evoked potential (AEP) monitor designed to estimate the depth of anaesthesia. It generates an "Alaris AEP index" (AAI), which is a dimensionless number scaled from 100 (awake) to 0. This study was designed to co...

journal_title：British journal of anaesthesia

authors： Kreuer S,Bruhn J,Larsen R,Hoepstein M,Wilhelm W

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Paradoxical excitement response during sedation consists of loss of affective control and abnormal movements. Chronic alcohol abuse has been proposed as a predisposing factor despite lack of supporting evidence. Because alcohol and propofol have a common site of action, we postulated that paradoxical excitem...

journal_title：British journal of anaesthesia

authors： Jeong S,Lee HG,Kim WM,Jeong CW,Lee SH,Yoon MH,Choi JI

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Chronic treatment with renin-angiotensin system (RAS) antagonists frequently causes deleterious hypotension during anaesthesia. We compared the effects of angiotensin II receptor antagonists (ARA) and angiotensin-converting enzyme inhibitors (ACEI) on neurohormonal levels and haemodynamics during cardiopulmo...

journal_title：British journal of anaesthesia

authors： Oh YJ,Lee JH,Nam SB,Shim JK,Song JH,Kwak YL

更新日期：2006-12-01 00:00:00

abstract：:During resection of a Wilms' tumour in a 10-year-old girl, sudden bradycardia, hypotension and cyanosis developed, leading to cardiac arrest. It was thought that part of the tumour had caused a pulmonary embolus. After prompt resuscitation, cardiopulmonary bypass surgery was started within 20 min. At operation the lef...

journal_title：British journal of anaesthesia

authors： Akyön MG,Arslan G

更新日期：1981-08-01 00:00:00