Haemostatic resuscitation.

Abstract:

:Recommendations for resuscitation of patients in early haemorrhagic shock, with active ongoing bleeding, have evolved in recent years. This review covers current theories of the pathophysiology of shock and recommended treatments, including damage control surgery, deliberate hypotensive management, administration of antifibrinolytics, early support of the coagulation system, and the possible role of deep anaesthesia. Future directions for resuscitation research are discussed.

journal_name

Br J Anaesth

authors

Dutton RP

doi

10.1093/bja/aes389

subject

Has Abstract

pub_date

2012-12-01 00:00:00

pages

i39-i46

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)31579-9

journal_volume

109 Suppl 1

pub_type

杂志文章,评审
  • Ketorolac trometamol for postoperative analgesia after orthopaedic surgery.

    abstract::We have compared the postoperative morphine requirements and analgesic efficacy of four doses of i.m. ketorolac 30 mg administered 6-hourly with placebo in a double-blind study of patients undergoing major or minor orthopaedic surgery. During the 24-h postoperative study period which began at the end of surgery, patie...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/69.1.19

    authors: Kinsella J,Moffat AC,Patrick JA,Prentice JW,McArdle CS,Kenny GN

    更新日期:1992-07-01 00:00:00

  • The minimum reservoir capacity necessary to avoid air-dilution. An experimental model of spontaneous breathing through a T-piece.

    abstract::The fresh gas flow rate necessary to prevent rebreathing in T-piece anaesthesia is well established at twice total ventilation. The minimum reservoir volume to avoid air dilution of anaesthetic gases in the alveolus at this flow rate is, however, undecided. A lung model was constructed to represent spontaneous respira...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/57.8.803

    authors: Naunton A

    更新日期:1985-08-01 00:00:00

  • Autotransfusion performed on a patient with cis AB blood group.

    abstract::Cis AB blood group is a rare variant of the AB blood group resulting from inheritance of both A and B genes on one chromosome. It may lead to misclassification in ABO grouping and clinical misdiagnosis as a result of its divergence from the laws of Landsteiner and Mendel. We encountered a case of cis AB blood group, a...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/83.3.491

    authors: Kawahito S,Kitahata H,Kimura H,Tanaka K,Oshita S

    更新日期:1999-09-01 00:00:00

  • Effect of atropine on the QT interval and T-wave amplitude in healthy volunteers.

    abstract::Prolongation of the QT interval of the ECG represents an imbalance in cardiac autonomic function and may predict cardiac arrhythmia. Vagal activity protects against prolongation of the QT interval which may be associated with flattening of the T-wave of the ECG. The changes in QT interval, T-wave amplitude and respira...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/71.5.736

    authors: Annila P,Yli-Hankala A,Lindgren L

    更新日期:1993-11-01 00:00:00

  • Blood-gas changes during induced hypotension with sodium nitroprusside.

    abstract::A blood-gas study of the respiratory effects of sodium nitroprusside during anaesthesia has shown a marked reduction in PaO2 when the drug was administered. After nitroprusside PaO2 returned to the previous values. It is suggested that the reduction in PaO2 is a result of an increased scatter of ventilation/perfusion ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/47.11.1205

    authors: Wildsmith JA,Drummond GB,MacRae WR

    更新日期:1975-11-01 00:00:00

  • Skin conductance monitoring compared with Bispectral Index to assess emergence from total i.v. anaesthesia using propofol and remifentanil.

    abstract:BACKGROUND:Arousal after sevoflurane anaesthesia has been detectable by monitoring changes in skin conductance (SC) with similar accuracy as monitoring Bispectral Index (BIS). As SC monitoring detects changes in sympathetic tone, the measurements might be confounded by the sympatholytic properties of propofol, a compon...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/ael278

    authors: Ledowski T,Bromilow J,Paech MJ,Storm H,Hacking R,Schug SA

    更新日期:2006-12-01 00:00:00

  • Variations in the gliding characteristics of 10-ml plastic syringes used to locate the extradural space by "loss of resistance" techniques.

    abstract::The gliding characteristics were evaluated of 10-ml plastic syringes used to identify the extradural space by "loss of resistance" techniques. This was undertaken quantitatively, by measuring the force necessary to depress syringe plungers, and qualitatively, by examining travel characteristics in terms of the force a...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/61.6.776

    authors: Bricker SR,Coleman P

    更新日期:1988-12-01 00:00:00

  • Rib cage contribution to resting and carbon dioxide stimulated ventilation during 1 MAC isoflurane anaesthesia.

    abstract::Using respiratory inductive plethysmography, we have measured rib cage and abdominal motion during isoflurane anaesthesia in 16 healthy day-surgery patients. Anaesthesia was induced with propofol and maintained with 1 MAC isoflurane in air-oxygen via a laryngeal mask. Measurements were taken during both resting ventil...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/67.6.712

    authors: Lumb AB,Petros AJ,Nunn JF

    更新日期:1991-12-01 00:00:00

  • Chronobiology of labour pain perception: an observational study.

    abstract:BACKGROUND:Circadian variation may affect many biological and pharmacological phenomena. METHODS:To assess circadian variations in labour pain perception, 222 consecutive nulliparous women with uncomplicated pregnancy, spontaneous labour, cervical dilatation (3-5 cm), ruptured membranes and normal fetal heart rate tra...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeh223

    authors: Aya AG,Vialles N,Mangin R,Robert C,Ferrer JM,Ripart J,de La Coussaye JE

    更新日期:2004-09-01 00:00:00

  • Do blood concentrations of neurone specific enolase and S-100 beta protein reflect cognitive dysfunction after abdominal surgery?ISPOCD Group.

    abstract::Neurone specific enolase (NSE) and S-100 beta protein have been used as markers of brain damage. We hypothesized that blood concentrations of NSE and S-100 beta protein reflect cognitive dysfunction after abdominal surgery. We studied 65 elderly patients in whom neuropsychological testing was performed before abdomina...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.bja.a013410

    authors: Rasmussen LS,Christiansen M,Rasmussen H,Kristensen PA,Moller JT

    更新日期:2000-02-01 00:00:00

  • Anaesthetic management of renin secreting nephroblastoma.

    abstract::We report the successful preoperative control and anaesthetic management of severe hypertension in a 7-month-old baby with nephroblastoma and increased renin activity. The strategy for selection of appropriate antihypertensive pharmacological agents and the anaesthetic implications and management of the condition are ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/69.2.206

    authors: Charlton GA,Sedgwick J,Sutton DN

    更新日期:1992-08-01 00:00:00

  • Comparison of midwife top-ups, continuous infusion and patient-controlled epidural analgesia for maintaining mobility after a low-dose combined spinal-epidural.

    abstract::We studied 133 women given a combined spinal-epidural for analgesia in labour. The initial intrathecal dose contained bupivacaine 2.5 mg with fentanyl 25 micrograms. When the mothers were comfortable, they were allocated randomly to one of three groups: continuous infusion (group Cl, n = 46), midwife top-ups (group MW...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/82.2.233

    authors: Collis RE,Plaat FS,Morgan BM

    更新日期:1999-02-01 00:00:00

  • Comparison of isoflurane and propofol-fentanyl anaesthesia in a swine model of asphyxia.

    abstract:BACKGROUND:There have been few studies comparing the response to asphyxia and the effectiveness of typical cardiopulmonary resuscitation (CPR) using exogenous epinephrine administration and manual closed-chest compression between total intravenous anaesthesia (TIVA) and inhalational anaesthesia. METHODS:Twenty pigs we...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeg259

    authors: Kurita T,Morita K,Kazama T,Sato S

    更新日期:2003-12-01 00:00:00

  • Maternal inspired oxygen concentration and neonatal status for caesarean section under general anaesthesia. Comparison of effects of 33% or 50% oxygen in nitrous oxide.

    abstract::The relationship between maternal FIO2 and umbilical venous PO2, PCO2, pH and neonatal Apgar and TSR (time to sustained respiration) scores was studied in 35 patients undergoing Caesarean section under general anaesthesia. Patients were allocated randomly to breathe an FIO2 of either 0.5 or 0.33. Umbilical venous bloo...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/61.3.250

    authors: Lawes EG,Newman B,Campbell MJ,Irwin M,Dolenska S,Thomas TA

    更新日期:1988-09-01 00:00:00

  • Possible effects of anaesthetic management on the 1 yr followed-up risk of herpes zoster after Caesarean deliveries.

    abstract:BACKGROUND:As general anaesthesia may compromise the immune system, it has been hypothesized that latent varicella-zoster virus is more likely to be reactivated and cause herpes zoster in mothers after Caesarean deliveries under general anaesthesia. Our study was thus aimed at investigating the risk of herpes zoster am...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer386

    authors: Chen YH,Rau RH,Keller JJ,Lin HC

    更新日期:2012-02-01 00:00:00

  • Cytokines and the immunomodulatory function of the vagus nerve.

    abstract::Cytokine synthesis and release is an essential component of the innate immune system, but inappropriate, excessive production results in a generalized systemic inflammatory response which damages distant organs. Recent research has identified an immunomodulatory function of the vagus nerve whereby activation of the ef...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aep037

    authors: Johnston GR,Webster NR

    更新日期:2009-04-01 00:00:00

  • Effects of sugammadex on incidence of postoperative residual neuromuscular blockade: a randomized, controlled study.

    abstract:BACKGROUND:This study aimed to investigate whether reversal of rocuronium-induced neuromuscular blockade with sugammadex reduced the incidence of residual blockade and facilitated operating room discharge readiness. METHODS:Adult patients undergoing abdominal surgery received rocuronium, followed by randomized allocat...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aev104

    authors: Brueckmann B,Sasaki N,Grobara P,Li MK,Woo T,de Bie J,Maktabi M,Lee J,Kwo J,Pino R,Sabouri AS,McGovern F,Staehr-Rye AK,Eikermann M

    更新日期:2015-11-01 00:00:00

  • Nausea and vomiting after cardiac surgery.

    abstract::We have undertaken a prospective, randomized study to determine the incidence of postoperative nausea and vomiting during intensive care stay after cardiac surgery, and to study the effect of addition of droperidol to an infusion of morphine used for postoperative analgesia. Data from 398 patients were examined. The u...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/77.3.356

    authors: Grebenik CR,Allman C

    更新日期:1996-09-01 00:00:00

  • The use of propanidid and lignocaine to reduce suxamethonium fasciculations.

    abstract::A technique of induction of anaesthesia using propanidid, lignocaine and suxamethonium is described, and the muscle fasciculations that follow it are shown to be significantly less than those accompanying induction with methohexitone and suxamethonium. ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/47.6.723

    authors: Fry EN

    更新日期:1975-06-01 00:00:00

  • Gastric emptying in pregnancy.

    abstract::The rate of gastric emptying in pregnancy was measured indirectly using the rate of paracetamol absorption in four groups of 15 patients: non-pregnant controls, first trimester patients presenting for termination of pregnancy, second trimester patients presenting for prostaglandin termination of pregnancy, and patient...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/67.1.54

    authors: Macfie AG,Magides AD,Richmond MN,Reilly CS

    更新日期:1991-07-01 00:00:00

  • Comparison of candidates who passed or failed the final (Part Three) examination for the F.F.A.R.C.S. (Eng.) in 1988.

    abstract::All 484 candidates for the 1988 Fellowship in Anaesthesia (Part Three) were surveyed to investigate any differences between successful and unsuccessful candidates in study techniques, work and domestic factors, and examination history that might lead to better guidance to those preparing for the examination and an imp...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/64.6.752

    authors: David AC,Elton RA,Spence AA,Hatch DJ

    更新日期:1990-06-01 00:00:00

  • Prediction of fluid responsiveness in patients during cardiac surgery.

    abstract:BACKGROUND:Left ventricular stroke volume variation (SVV) has been shown to be a predictor of fluid responsiveness in various subsets of patients. However, the accuracy and reliability of SVV are unproven in patients ventilated with low tidal volumes. METHODS:Fourteen patients were studied immediately after coronary a...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeh280

    authors: Rex S,Brose S,Metzelder S,Hüneke R,Schälte G,Autschbach R,Rossaint R,Buhre W

    更新日期:2004-12-01 00:00:00

  • Does the addition of clonidine affect duration of analgesia of bupivacaine wound infiltration in inguinal hernia surgery?

    abstract::We conducted a prospective, randomized, double-blind study to compare analgesia obtained by wound infiltration using 29 ml of 0.25% bupivacaine alone, or with the addition of clonidine hydrochloride 150 micrograms. A third group received bupivacaine wound infiltration with clonidine 150 micrograms i.m. to control for ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/79.4.446

    authors: Elliott S,Eckersall S,Fligelstone L,Jothilingam S

    更新日期:1997-10-01 00:00:00

  • Apoptotic insults to human HepG2 cells induced by S-(+)-ketamine occurs through activation of a Bax-mitochondria-caspase protease pathway.

    abstract:BACKGROUND:Ketamine is widely used as an i.v. anaesthetic agent and as a drug of abuse. Hepatocytes contribute to the metabolism of endogenous and exogenous substances. This study evaluated the toxic effects of S-(+)-ketamine and possible mechanisms using human hepatoma HepG2 cells as the experimental model. METHODS:H...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aen322

    authors: Lee ST,Wu TT,Yu PY,Chen RM

    更新日期:2009-01-01 00:00:00

  • Enjoying work or burdened by it? How anaesthetists experience and handle difficulties at work: a qualitative study.

    abstract:BACKGROUND:The aim of this study was to explore difficulties at work from anaesthetists' own perspective and to examine how anaesthetists handle and cope with situations that are perceived as difficult and potentially stressful. METHODS:Two sets of interviews were conducted with 19 specialist anaesthetists in Sweden. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,多中心研究

    doi:10.1093/bja/aem233

    authors: Larsson J,Rosenqvist U,Holmström I

    更新日期:2007-10-01 00:00:00

  • Comparison of the effects of thoracic and lumbar epidural anaesthesia on induction and maintenance doses of propofol during total i.v. anaesthesia.

    abstract:BACKGROUND:In this randomized, double-blind study, the effects of thoracic and lumbar epidural anaesthesia on the induction doses (IDs) and maintenance doses (MDs) of propofol during bispectral index (BIS) guided total i.v. anaesthesia were compared. METHODS:Fifty-four patients (three groups, n=18 each) undergoing uro...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aen160

    authors: Sentürk M,Güçyetmez B,Ozkan-Seyhan T,Karadeniz M,Dinçer S,Akpir D,Sengül T,Denkel T

    更新日期:2008-08-01 00:00:00

  • Smaller children have greater bupivacaine plasma concentrations after ilioinguinal block.

    abstract::We have measured plasma concentrations of bupivacaine after ilioinguinal block in children of different sizes. We studied 14 children with weights 10-15 kg and 17 children with weights 15-30 kg. Each child received 0.5% bupivacaine 0.25 ml kg-1 (1.25 mg kg-1) (Carbostesin, Astra, Germany). Venous blood was obtained be...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/76.3.452

    authors: Smith T,Moratin P,Wulf H

    更新日期:1996-03-01 00:00:00

  • Comparison of S(-)-bupivacaine with racemic (RS)-bupivacaine in supraclavicular brachial plexus block.

    abstract::Bupivacaine is used widely as a local anaesthetic but has potential for severe cardiovascular and central nervous system (CNS) toxicity. It has an asymmetric carbon atom giving it a chiral centre, and the commercial preparation is a racemic mixture of its two enantiomers: dextro or R(+)-bupivacaine and levo or S(-)-bu...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/80.5.594

    authors: Cox CR,Checketts MR,Mackenzie N,Scott NB,Bannister J

    更新日期:1998-05-01 00:00:00

  • Differential effects of neuromuscular blocking agents on suxamethonium-induced fasciculations and myalgia.

    abstract::The effect of pretreatment with suxamethonium, gallamine or pancuronium on suxamethonium-induced fasciculations and myalgia was studied in a controlled, randomized and double-blind clinical trial. Both fasciculations and myalgia were assessed on a four-point rating scale. There was no significant correlation between f...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/60.4.367

    authors: O'Sullivan EP,Williams NE,Calvey TN

    更新日期:1988-03-01 00:00:00

  • Pulse oximetry plethysmographic waveform during changes in blood volume.

    abstract::Systolic pressure variation (SPV) and its dDown component have been shown to be sensitive factors in estimating intravascular volume in patients undergoing mechanical ventilation. In this study, ventilation-induced changes in pulse oximeter plethysmographic waveform were evaluated after removal and after reinfusion of...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/82.2.178

    authors: Shamir M,Eidelman LA,Floman Y,Kaplan L,Pizov R

    更新日期:1999-02-01 00:00:00