Differential effects of neuromuscular blocking agents on suxamethonium-induced fasciculations and myalgia.

abstract：:The rapid detection and evaluation of patients presenting with perioperative neurological dysfunction is of great clinical relevance. Biomarkers have been defined as biological molecules that can be used as an indicator of new onset or progression of a biological process or effect of treatment. Biomarkers have become ...

journal_title：British journal of anaesthesia

authors： Cata JP,Abdelmalak B,Farag E

更新日期：2011-12-01 00:00:00

abstract：:The value of the continuous monitoring of end-tidal carbon dioxide concentration as an indicator of the acute intraoperative interruption of pulmonary blood flow, in patients with pre-existing restrictions of pulmonary blood flow undergoing closed heart surgery, is illustrated by two case reports. Decreases in end-tid...

journal_title：British journal of anaesthesia

authors： Schuller JL,Bovill JG,Nijveld A

更新日期：1985-12-01 00:00:00

abstract：:Animal studies suggest that alpha 2 agonists inhibit the chemoreceptor response to hypoxia. We have examined the effect of oral clonidine on the ventilatory response to sustained, isocapnic hypoxia (SpO2 79.7% (SD 1.1%) for 20 min) in eight male subjects. The hypoxic ventilatory response was measured before and after ...

journal_title：British journal of anaesthesia

authors： Foo IT,Warren PM,Drummond GB

更新日期：1996-02-01 00:00:00

abstract：:During resection of a Wilms' tumour in a 10-year-old girl, sudden bradycardia, hypotension and cyanosis developed, leading to cardiac arrest. It was thought that part of the tumour had caused a pulmonary embolus. After prompt resuscitation, cardiopulmonary bypass surgery was started within 20 min. At operation the lef...

journal_title：British journal of anaesthesia

authors： Akyön MG,Arslan G

更新日期：1981-08-01 00:00:00

abstract：:We have determined the effect of pretreatment with mivacurium on the potency of suxamethonium and the effect of prior administration of suxamethonium on the potency of mivacurium. We studied 100 ASA I or II patients during thiopentone-fentanyl-nitrous oxide-isoflurane anaesthesia. Neuromuscular block was recorded as t...

journal_title：British journal of anaesthesia

authors： Naguib M,Abdulatif M,Selim M,al-Ghamdi A

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:The effects of thoracic epidural anaesthesia (TEA) on gastric mucosal microvascular haemoglobin oxygenation (microHbO(2)) are unclear. At the splanchnic level, reduction of sympathetic tone may promote vasodilation and increase microHbO(2). However, these splanchnic effects are counteracted by systemic effec...

journal_title：British journal of anaesthesia

authors： Schwarte LA,Picker O,Höhne C,Fournell A,Scheeren TW

更新日期：2004-10-01 00:00:00

abstract：:We have studied post-tetanic count (PTC) and single twitch height at the onset of reflex movement to carinal stimulation after administration of vecuronium with five different types of anaesthesia. Seventy-five adult patients were allocated randomly to five groups of 15 patients each, to receive one of the following a...

journal_title：British journal of anaesthesia

authors： Saitoh Y,Kaneda K,Toyooka H,Amaha K

更新日期：1994-06-01 00:00:00

abstract：:Forty patients who had undergone coronary artery graft surgery and who required vasodilator therapy for postoperative hypertension were given infusions of either alfentanil or morphine together with bolus doses of midazolam for sedation and analgesia while ventilation was controlled artificially. Sodium nitroprusside ...

journal_title：British journal of anaesthesia

authors： McMenemin IM,Church JA,Kenny GN

更新日期：1988-12-01 00:00:00

abstract：:A mathematical model of a subject breathing from a circle system has been used to follow the course of anaesthetic uptake during the simulated administration of 60% nitrous oxide, 2% halothane and 2% methoxyflurane, under non-rebreathing conditions and with fresh gas flows to the circle system of between 8 and 0.25 li...

journal_title：British journal of anaesthesia

authors： Conway CM

更新日期：1986-10-01 00:00:00

abstract：:The sedation of 50 children aged 6 months to 9 years who had undergone open heart surgery was studied. During artificial ventilation a midazolam infusion was used in conjunction with the administration of morphine (and tubocurarine). Sedation for patients breathing spontaneously with positive airway pressure was conti...

journal_title：British journal of anaesthesia

authors： Booker PD,Beechey A,Lloyd-Thomas AR

更新日期：1986-10-01 00:00:00

abstract：:Bupivacaine 2.5 mg kg-1 (0.5 ml kg-1 of 0.5% solution), with or without adrenaline 5 micrograms ml-1, was administered by interpleural injection to 12 patients after elective cholecystectomy. Noncompartmental analysis indicated that the addition of adrenaline had no effect on total body clearance, apparent volume of d...

journal_title：British journal of anaesthesia

authors： Gin T,Chan K,Kan AF,Gregory MA,Wong YC,Oh TE

更新日期：1990-06-01 00:00:00

abstract：:We have studied the effects of bilateral ilioinguinal nerve block and wound infiltration with 0.5% bupivacaine on postoperative pain and analgesic requirements in 62 patients undergoing Caesarean section under general anaesthesia. A control group received no local anaesthetic supplementation. Both ilioinguinal block a...

journal_title：British journal of anaesthesia

authors： Ganta R,Samra SK,Maddineni VR,Furness G

更新日期：1994-02-01 00:00:00

abstract：:The Myotest is a new nerve stimulator which can give train-of-four, single twitch (1 and 10 s) and tetanic stimuli. Power is supplied by standard batteries, which allow 200 h effective use. The impulse is unipolar constant current, and the amplitude can be adjusted between 0 and 40 mA. These factors, plus the electron...

journal_title：British journal of anaesthesia

authors： Viby-Mogensen J,Hansen PH,Jørgensen BC,Ording H,Kann T,Fries B

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND:To determine whether temperature and haematocrit (Hct) alter the relationship between blood flow (BF) and blood flow velocity (BFV). METHODS:Using a transcranial Doppler apparatus, we measured the peak velocity of whole blood cells pumped by a cardiopulmonary bypass (CPB) circuit, through a 0.15-cm internal...

journal_title：British journal of anaesthesia

authors： Paut O,Bissonnette B

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Intraneural injection of local anaesthetic agents carries a risk of neurological complications. Early detection of intraneural needle-tip position is very important in the initial phase of injection. Ultrasound (US) characteristics for real-time detection of intraneural injections have been described, but on...

journal_title：British journal of anaesthesia

authors： Moayeri N,Krediet AC,Welleweerd JC,Bleys RL,Groen GJ

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The usefulness of the PFA-100 in assessing the risk of bleeding in non-cardiac surgery is not clear. This study aims to examine this by correlating preoperative PFA-100 measurement with perioperative bleeding in patients receiving cyclooxygenase (COX) inhibitors. METHODS:PFA-100 with adenosine-5'-diphosphat...

journal_title：British journal of anaesthesia

authors： Ng KF,Lawmin JC,Tsang SF,Tang WM,Chiu KY

更新日期：2009-06-01 00:00:00

abstract：:Plasma concentrations of amethocaine were measured after topical application of amethocaine cream 2 g (5% w/w) to the dorsum of the right hand of 10 adult volunteers. The cream was applied for 240 min and plasma was assayed for amethocaine and its metabolite p-n-butylaminobenzoic acid at 0, 30, 60, 90, 120 and 240 min...

journal_title：British journal of anaesthesia

authors： Mazumdar B,Tomlinson AA,Faulder GC

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Clonidine is a useful analgesic-sedative agent; however, few data exist regarding its use in infants after congenital heart disease surgery. We thus aimed to assess the absorption and safety of enterally administered clonidine in this setting. METHODS:Sixteen infants (median age 6.7 months) received a singl...

journal_title：British journal of anaesthesia

authors： Arenas-Lopez S,Mulla H,Manna S,Durward A,Murdoch IA,Tibby SM

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The debate on lung-protective ventilation strategies for surgical patients is ongoing. Evidence suggests that the use of low tidal volume VT improves clinical outcomes. However, the optimal levels of PEEP and recruitment manoeuvre (RM) strategies incorporated into low VT ventilation remain unclear. METHODS:...

journal_title：British journal of anaesthesia

authors： Deng QW,Tan WC,Zhao BC,Wen SH,Shen JT,Xu M

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:We studied the potential neuroprotective effects of halothane and desflurane, compared with the awake state, on infarct size following 2 h of intraluminal middle cerebral artery occlusion (MCAo) and 22 h of reperfusion. METHODS:Male Sprague-Dawley rats were anaesthetized with desflurane or halothane, intuba...

journal_title：British journal of anaesthesia

authors： Haelewyn B,Yvon A,Hanouz JL,MacKenzie ET,Ducouret P,Gérard JL,Roussel S

更新日期：2003-09-01 00:00:00

abstract：Background:Checklists can reduce medical errors. However, the effectiveness of checklists is hampered by lack of acceptance and compliance. Recently, a new type of checklist with dynamic properties has been created to provide more specific checklist items for each individual patient. Our purpose in this simulation-base...

journal_title：British journal of anaesthesia

authors： De Bie AJR,Nan S,Vermeulen LRE,Van Gorp PME,Bouwman RA,Bindels AJGH,Korsten HHM

更新日期：2017-08-01 00:00:00

abstract：:We studied 40 elderly patients undergoing cataract surgery. Ten non-insulin-dependent diabetes mellitus (NIDDM) patients received standardized general anaesthesia, 10 NIDDM patients received local anaesthesia using retrobulbar block, 10 non-diabetic control patients received general anaesthesia and 10 non-diabetic con...

journal_title：British journal of anaesthesia

authors： Barker JP,Robinson PN,Vafidis GC,Burrin JM,Sapsed-Byrne S,Hall GM

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The minimum effective volume of local anaesthetic needed to provide effective analgesia of the four main branches of the axillary brachial plexus is unknown. This study was performed to determine the minimum volume of local anaesthetic required to surround the nerves of the axillary brachial plexus and docum...

journal_title：British journal of anaesthesia

authors： Harper GK,Stafford MA,Hill DA

更新日期：2010-05-01 00:00:00

abstract：:The isolated rat hepatocyte model has been used to assess the hepatotoxicity of a number of i.v. anaesthetic induction agents. Ketamine, Althesin and CCI 12923 (minaxolone) all inhibited gluconeogenesis and urea formation from alanine. There was also a decrease in the cell ATP concentration, and a dose-related increas...

journal_title：British journal of anaesthesia

authors： Sear JW,McGivan JD

更新日期：1979-08-01 00:00:00

abstract：:In a prospective double-blind study, single dose lumbar extradural blockade was instituted in 80 healthy male patients undergoing lower abdominal surgery. Patients were assigned randomly to one of four groups. Each group received treatment with 0.5% bupivacaine 20 ml containing adrenaline 1:200 000. To this solution w...

journal_title：British journal of anaesthesia

authors： Rucci FS,Cardamone M,Migliori P

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Guidelines recommend discontinuation of clopidogrel for 7 days before a neuraxial injection, while other directives suggest that 5 days might be adequate. We examined the time course of antiplatelet activity after clopidogrel discontinuation in patients undergoing epidural injections. METHODS:Thirteen patie...

journal_title：British journal of anaesthesia

authors： Benzon HT,McCarthy RJ,Benzon HA,Kendall MC,Robak S,Lindholm PF,Kallas PG,Katz JA

更新日期：2011-12-01 00:00:00

abstract：:The concentrations of volatile hydrocarbons were studied in breath samples from patients before and after anaesthesia. In patients to whom halothane was administered, there was a significant increase in the concentration of isobutene (from 0.43 +/- 0.09 to 4.66 +/- 2.22 nmol litre-1). There was no change in the concen...

journal_title：British journal of anaesthesia

authors： Hempel V,May R,Frank H,Remmer H,Köster U

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Signalling of several G-protein-coupled receptors of the Gq/11 family is time-dependently inhibited by local anaesthetics (LAs). Since LA-induced modulation of muscarinic m1 and m3 receptor function may explain their beneficial effects in clinical practice, such as decreased postoperative cognitive dysfuncti...

journal_title：British journal of anaesthesia

authors： Picardi S,Stevens MF,Hahnenkamp K,Durieux ME,Lirk P,Hollmann MW

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Cyclic redistribution of air within the cuff during respiratory pressure changes creates a self-sealing mechanism which allows tracheal sealing, despite tracheal airway pressure being above baseline cuff inflation pressure. The aim of the present study was to investigate the effect of continuous automated cu...

journal_title：British journal of anaesthesia

authors： Weiss M,Doell C,Koepfer N,Madjdpour C,Woitzek K,Bernet V

更新日期：2009-02-01 00:00:00

abstract：:A retrospective study was carried out to determine analgesic requirements in a group of orthopaedic outpatients (n = 145) and oral surgery inpatients (n = 172). The orthopaedic patients received a codeine-paracetamol premedication, an opioid during operation, or no analgesic. Less than 50% of the orthopaedic patients ...

journal_title：British journal of anaesthesia

authors： Campbell WI

更新日期：1990-05-01 00:00:00