Abstract:
BACKGROUND:Cyclic redistribution of air within the cuff during respiratory pressure changes creates a self-sealing mechanism which allows tracheal sealing, despite tracheal airway pressure being above baseline cuff inflation pressure. The aim of the present study was to investigate the effect of continuous automated cuff pressure regulation on tracheal sealing during cyclic respiratory pressure changes. METHODS:In vitro tracheal sealing was studied in four different high volume-low pressure (HVLP) tracheal tube cuffs size internal diameter 8.0 and 5.0 mm in combination with a conventional pressure manometer and two different automated pressure controllers (VBM Cuff Controller; Cuff Pressure Control Tracoe). Experiments were performed at 10, 15, 20, and 25 cm H(2)O cuff pressure during intermittent positive pressure ventilation with peak inspiratory pressures of 20 and 25 cm H(2)O. Air leakage was assessed spirometrically. Experiments were performed four times with each tube brand and size with two exemplars of each of the three cuff pressure controllers. RESULTS:Owing to immediate cuff pressure correction, tracheal sealing at cuff pressure below inspiratory pressure was reduced in most of the tracheal tube cuffs, except in those with reduced sealing characteristics when using the Pressure Control Tracoe compared with the conventional pressure manometer and the VBM Cuff Controller. Tracheal sealing with the Pressure Control Tracoe comparable with the other two devices was only achieved at cuff pressures of 20 and 25 cm H(2)O. CONCLUSIONS:Automated cuff pressure controllers with rapid pressure correction interfere with the self-sealing mechanism of high sealing HVLP tube cuffs and reduce their improved sealing characteristics.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Weiss M,Doell C,Koepfer N,Madjdpour C,Woitzek K,Bernet Vdoi
10.1093/bja/aen355subject
Has Abstractpub_date
2009-02-01 00:00:00pages
273-8issue
2eissn
0007-0912issn
1471-6771pii
S0007-0912(17)34543-9journal_volume
102pub_type
杂志文章abstract:BACKGROUND:Multiple studies have shown that cerebral tissue oxygen saturation (Sct(O(2))) is decreased after phenylephrine treatment. We hypothesized that the negative impact of phenylephrine administration on Sct(O(2)) is affected by arterial blood carbon dioxide partial pressure (Pa(CO(2))) because CO(2) is a powerfu...
journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章
doi:10.1093/bja/aes023
更新日期:2012-05-01 00:00:00
abstract::Percutaneous dilatational tracheostomy (PDT) is associated with a number of life-threatening complications. We present a case of massive and fatal arterial haemorrhage that occurred in the intensive care unit during an elective PDT on an 86-year-old woman following earlier evacuation of a traumatic subdural haematoma....
journal_title:British journal of anaesthesia
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journal_title:British journal of anaesthesia
pub_type: 杂志文章,随机对照试验
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abstract::Profound postoperative respiratory depression after larger doses of fentanyl was partially reversed by 4-aminopyridine. This reversal was independent of FIO2' suggesting that the response was not dependent upon peripheral chemoreceptor-mediated drive. Similar reversal of fentanyl-induced depression by 4-aminopyridine ...
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doi:10.1093/bja/53.4.373
更新日期:1981-04-01 00:00:00
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journal_title:British journal of anaesthesia
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journal_title:British journal of anaesthesia
pub_type: 杂志文章
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journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1988-04-01 00:00:00
abstract::Intrathecal midazolam causes antinociception by combining with spinal cord benzodiazepine receptors. This effect is reversible with doses of naloxone, suggesting involvement of spinal kappa or delta but not mu opioid receptors. The antinociceptive effects of intrathecally administered drugs in the spinal cord were dem...
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journal_title:British journal of anaesthesia
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更新日期:2000-04-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 杂志文章
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更新日期:1994-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-01-01 00:00:00
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journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:British journal of anaesthesia
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1988-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:1998-03-01 00:00:00