Monitoring of end-tidal carbon dioxide partial pressure during high frequency jet ventilation.

Abstract:

:A new method has been developed to measure end-tidal carbon dioxide partial pressure (PECO2) during high frequency jet ventilation (HFJV). A digital flow controller incorporated in a computerized high frequency jet ventilator was used to deliver either a single deep breath or a series of three deep breaths. On user request, HFJV was interrupted and the deep breaths delivered, after which HFJV was resumed. Using a mathematical model, we were able to predict accurately the pressures to which the lungs would be inflated during deep breaths. The effect of varying the deep breath pressure (Pdb) on the ratio of end-tidal PCO2 to arterial (PCO2 (PECO2:PaCO2) was studied in three dogs. In all the dogs, within an optimum Pdb range of 5-10 cm H2O, PECO2 during the first deep breath was found to be similar (+/- 0.2 kPa) to the PaCO2 immediately before the onset of deep breaths. Deep breaths delivered above or below the optimum Pdb range resulted in a decrease in the ratio PECO2:PaCO2. The frequency of jet ventilation (12-200 b.p.m.) before the onset of the deep breaths did not affect PECO2:PaCO2.

journal_name

Br J Anaesth

authors

Sehati S,Young JD,Sykes MK,McLeod CN

doi

10.1093/bja/63.7.47

subject

Has Abstract

pub_date

1989-01-01 00:00:00

pages

47S-52S

issue

7 Suppl 1

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)49938-7

journal_volume

63

pub_type

杂志文章
  • Effect of methylene blue on the absorbance of solutions of haemoglobin.

    abstract::The effect of the i.v. administration of methylene blue dye on haemoglobin oxygen saturation, measured by a pulse oximeter was investigated. The absorption spectra of various concentrations of haemoglobin, oxyhaemoglobin and methylene blue were compared. The amount of 660-nm light absorbed by methylene blue was suffic...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/60.4.439

    authors: Gorman ES,Shnider MR

    更新日期:1988-03-01 00:00:00

  • Tetanic stimulus of ulnar nerve as a predictor of heart rate response to skin incision in propofol remifentanil anaesthesia.

    abstract:BACKGROUND:To study adequate antinociception during general anaesthesia, tetanic stimulus of 5-10 s duration has been used previously as a standardized nociceptive stimulus. However, such stimuli have been found to correlate poorly with intraoperative nociception. We hypothesized that an electrical tetanic stimulus of ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aem200

    authors: Rantanen M,Yppärilä-Wolters H,van Gils M,Yli-Hankala A,Huiku M,Kymäläinen M,Korhonen I

    更新日期:2007-10-01 00:00:00

  • Anaesthesia for peculiar cells--a century of sickle cell disease.

    abstract::Sickle cell disease is a congenital haemoglobinopathy with a high incidence of perioperative complications. Traditional anaesthetic management, based largely on extrapolation from biochemical models, has emphasized avoidance of red cell sickling to prevent exacerbations of the disease. This historical review outlines ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aei129

    authors: Firth PG

    更新日期:2005-09-01 00:00:00

  • Influence of bolus doses of phenoperidine on intracranial pressure and systemic arterial pressure in traumatic coma.

    abstract::The effects of bolus doses of phenoperidine 1-2 mg i.v. either alone, or combined with pancuronium 2-4 mg, were investigated in seven patients in traumatic coma. Phenoperidine alone significantly reduced mean arterial pressure (MAP) by a mean (+/- SEM) of 13.2 (+/- 2.8) mm Hg. Overall there was no significant change i...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/59.5.592

    authors: Bingham RM,Hinds CJ

    更新日期:1987-05-01 00:00:00

  • Population pharmacokinetics of single-dose intravenous paracetamol in children.

    abstract:BACKGROUND:To determine the pharmacokinetics (PK) of a new i.v. formulation of paracetamol (Perfalgan) in children ≤15 yr of age. METHODS:After obtaining written informed consent, children under 16 yr of age were recruited to this study. Blood samples were obtained at 0, 15, 30 min, 1, 2, 4, 6, and 8 h after administr...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aes025

    authors: Mohammed BS,Engelhardt T,Cameron GA,Cameron L,Hawksworth GM,Hawwa AF,McElnay J,Helms PJ,McLay JS

    更新日期:2012-05-01 00:00:00

  • Determination of ED95 of a single-bolus dose of dexmedetomidine for adequate sedation in children and adolescents with and without obesity.

    abstract:BACKGROUND:With the increasing prevalence of children who are overweight and with obesity, anaesthesiologists must determine the optimal dosing of medications given the altered pharmacokinetics and pharmacodynamics in this population. We therefore determined the single dose of dexmedetomidine that provided sufficient s...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2020.11.037

    authors: Wu B,Shan J,Zhou Q,Wang L

    更新日期:2021-01-22 00:00:00

  • Effects of halothane on respiratory mechanics and lung histopathology in normal rats.

    abstract::It is generally accepted that halothane reduces airway and tissue resistance in lungs with preexisting airway tone. However, under conditions of resting airway tone, pulmonary resistance remains unaltered. In this study, we have determined the effects of halothane on respiratory system, pulmonary and chest wall resist...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/oxfordjournals.bja.a013443

    authors: Reta GS,Riva JA,Piriz H,Medeiros AS,Rocco PR,Zin WA

    更新日期:2000-03-01 00:00:00

  • Observations on extradural morphine analgesia in various pain conditions.

    abstract::We report the extradural administration of low-dose morphine in 10 ml of 10% dextrose (2-3 mg) to 98 adult patients with various types of acute and chronic pain. Extradural morphine injections were given either via a Tuohy needle (single or repeat injection) or via an extradural catheter. Pain relief was evaluated by ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/52.3.247

    authors: Magora F,Olshwang D,Eimerl D,Shorr J,Katzenelson R,Cotev S,Davidson JT

    更新日期:1980-03-01 00:00:00

  • Isoflurane impairs odour discrimination learning in rats: differential effects on short- and long-term memory.

    abstract:BACKGROUND:Anaesthetics suppress the formation of lasting memories at concentrations that do not suppress perception, but it is unclear which elements of the complex cascade leading from a conscious experience to a lasting memory trace are disrupted. Experiments in conscious humans suggest that subhypnotic concentratio...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer451

    authors: Pearce RA,Duscher P,Van Dyke K,Lee M,Andrei AC,Perouansky M

    更新日期:2012-04-01 00:00:00

  • Efficacy of nitroglycerin inhalation in reducing pulmonary arterial hypertension in children with congenital heart disease.

    abstract:BACKGROUND:There has been a renewed interest in nitric oxide donor drugs, such as nitroglycerin, delivered by the inhalational route for treatment of pulmonary arterial hypertension (PAH). We investigated the acute effects of inhaled nitroglycerin on pulmonary and systemic haemodynamics in children with PAH associated ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/ael112

    authors: Goyal P,Kiran U,Chauhan S,Juneja R,Choudhary M

    更新日期:2006-08-01 00:00:00

  • Ropivacaine 0.75% for extradural anaesthesia in elective caesarean section: an open clinical and pharmacokinetic study in mother and neonate.

    abstract::In an open study we have investigated the efficacy of 20 ml of 0.75% ropivacaine (7.5 mg ml-1) to provide extradural anaesthesia for elective Caesarean section. Plasma concentrations (total and free) were estimated in the mother and neonate. Anaesthesia was effective and safe. Plasma concentrations of ropivacaine in t...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/79.1.3

    authors: Morton CP,Bloomfield S,Magnusson A,Jozwiak H,McClure JH

    更新日期:1997-07-01 00:00:00

  • Gastric emptying in pregnancy.

    abstract::The rate of gastric emptying in pregnancy was measured indirectly using the rate of paracetamol absorption in four groups of 15 patients: non-pregnant controls, first trimester patients presenting for termination of pregnancy, second trimester patients presenting for prostaglandin termination of pregnancy, and patient...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/67.1.54

    authors: Macfie AG,Magides AD,Richmond MN,Reilly CS

    更新日期:1991-07-01 00:00:00

  • Perianaesthetic risks and outcomes of abdominal surgery for metastatic carcinoid tumours.

    abstract::Patients with metastatic carcinoid tumours often undergo surgical procedures to reduce the tumour burden and associated debilitating symptoms. These procedures and anaesthesia can precipitate a life-threatening carcinoid crisis. To assess perioperative outcomes, we studied retrospectively the medical records of adult ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/87.3.447

    authors: Kinney MA,Warner ME,Nagorney DM,Rubin J,Schroeder DR,Maxson PM,Warner MA

    更新日期:2001-09-01 00:00:00

  • Priming of pancuronium with magnesium.

    abstract::Magnesium inhibits the release of acetylcholine from the motor nerve terminal and thus potentiates the action of the non-depolarizing neuromuscular blocking drugs. We have examined the possibility that this effect might enhance the speed of onset of non-depolarizing block with pancuronium. Following the administration...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/66.2.247

    authors: James MF,Schenk PA,van der Veen BW

    更新日期:1991-02-01 00:00:00

  • Minimum alveolar concentration (MAC) of xenon in intubated swine.

    abstract:BACKGROUND:The minimum alveolar concentration (MAC) is a traditional index of the hypnotic potency of an inhalational anaesthetic. To investigate the anaesthetic as well as the unwanted effects of xenon (Xe) in a swine model, it is useful to know MAC(Xe). METHODS:The study was performed using ten swine (weight 27.8-35...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aeh077

    authors: Hecker KE,Horn N,Baumert JH,Reyle-Hahn SM,Heussen N,Rossaint R

    更新日期:2004-03-01 00:00:00

  • The use of a digital computer for the on-line real-time assessment of neuromuscular blockade in anaesthetized man.

    abstract::A computer program written mainly in a high level language (ALGOL), but with the sampling routine and certain calculations written in assembly language (SIR), has been developed to assess neuromuscular blockade in anaesthetized man by means of an Elliott 903 digital computer. The program allows the on-line real-time a...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/47.10.1097

    authors: Perry IR,Worsley R,Sugai N,Payne JP

    更新日期:1975-10-01 00:00:00

  • Influence of muscle temperature and forearm position on evoked electromyography in the hand.

    abstract::We have examined the correlation between the evoked electromyographic response in the first dorsal interosseous muscle of the hand, temperature and forearm position in 40 female patients after enflurane anaesthesia with spontaneous breathing. In 20 patients the supinated forearm with the wrist extended was immobilized...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/72.4.407

    authors: Smith DC,Booth JV

    更新日期:1994-04-01 00:00:00

  • Patient-controlled interscalene analgesia with ropivacaine after major shoulder surgery: PCIA vs PCA.

    abstract::We have compared the efficacy of patient-controlled interscalene analgesia (PCIA) using ropivacaine with patient-controlled analgesia (PCA) using nicomorphine in 60 patients (n = 30 in each group), in a prospective, randomized study. In both groups, all patients received interscalene block with 0.75% ropivacaine befor...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/81.4.603

    authors: Borgeat A,Tewes E,Biasca N,Gerber C

    更新日期:1998-10-01 00:00:00

  • Single dose parecoxib significantly improves ventilatory function in early extubation coronary artery bypass surgery: a prospective randomized double blind placebo controlled trial.

    abstract:BACKGROUND:Parecoxib, a cyclo oxygenase-2 inhibiting non-steroidal anti-inflammatory drug, has been widely used for postoperative analgesia. Our aim was to quantify the benefit of a single dose after coronary artery bypass grafting. METHODS:The investigation was carried out as a randomized double blind placebo control...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aei298

    authors: Khalil MW,Chaterjee A,Macbryde G,Sarkar PK,Marks RR

    更新日期:2006-02-01 00:00:00

  • Nerve injury by needle nerve perforation in regional anaesthesia: does size matter?

    abstract:BACKGROUND:In regional anaesthesia, there is a risk of direct nerve injury. The purpose of this study was to determine whether the diameter of the applied needle is associated with the magnitude of nerve injury after needle nerve perforation. METHODS:In five anaesthetized pigs, the brachial plexus were exposed bilater...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aep366

    authors: Steinfeldt T,Nimphius W,Werner T,Vassiliou T,Kill C,Karakas E,Wulf H,Graf J

    更新日期:2010-02-01 00:00:00

  • Malignant hyperthermia in Belgian Landrace pigs rested or exercised before exposure to halothane.

    abstract::Thirteen of 31 Belgian Landrace pigs developed malignant hyperthermia (MH) after breathing halothane. A short period of exercise 1 h before the administration of the triggering agent increased the incidence of the syndrome to 100% in eight similar pigs. Clinical symptoms were more marked and developed more rapidly in ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/48.9.821

    authors: van den Hende C,Lister D,Muylle E,Ooms L,Oyaert W

    更新日期:1976-09-01 00:00:00

  • Comparison of speed of onset of analgesic effect of diamorphine and morphine.

    abstract::In a random, double-blind crossover trial using an ischaemic limb pain model we have assessed the speed of onset of analgesia after an i.v. bolus of equipotent doses of diamorphine and morphine in 12 healthy male volunteers. Pain and its subsequent relief were assessed by means of a visual analogue scale. Two of the s...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/66.6.656

    authors: Morrison LM,Payne M,Drummond GB

    更新日期:1991-06-01 00:00:00

  • Cerebrovascular effects of isoflurane in man. Intracranial pressure and middle cerebral artery flow velocity.

    abstract::Twelve hydrocephalic patients undergoing hydrodynamic studies and shunt procedures during general anaesthesia were subjected to short term observations of the cerebrovascular effects of isoflurane. Intraventricular pressure (IVP), arterial pressure (AP); cerebral perfusion pressure (CPP = AP-IVP), end-tidal PCO2, Cere...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/59.10.1208

    authors: Lundar T,Lindegaard KF,Refsum L,Rian R,Nornes H

    更新日期:1987-10-01 00:00:00

  • Termination of supraventricular tachycardia by propofol.

    abstract::It is known that propofol can have effects on atrioventricular node conduction. We report a case where administration of propofol was associated with termination of supraventricular tachycardia. Although a similar phenomenon has been reported in children, this is the first such case in an adult. ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:

    authors: Kannan S,Sherwood N

    更新日期:2002-06-01 00:00:00

  • Laparoscopy: blood-gas values and minor sequelae associated with three techniques based on isoflurane.

    abstract::Three anaesthetic techniques based on isoflurane were compared in outpatients undergoing laparoscopy. Sixty healthy patients were randomly allocated to receive isoflurane via mask (spontaneous respiration), via tracheal tube (spontaneous respiration) or via tracheal tube with controlled ventilation. Moderate hypercarb...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/59.2.189

    authors: Kenefick JP,Leader A,Maltby JR,Taylor PJ

    更新日期:1987-02-01 00:00:00

  • The intubating laryngeal mask airway compared with direct laryngoscopy.

    abstract::We have compared the ability of naïve intubators to intubate the trachea using a laryngoscope and an intubating laryngeal mask airway (ILMA) after receiving basic training, in a randomized, prospective, crossover study in 60 patients. Ventilation of the lungs via the ILMA was also compared with ventilation with a face...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/83.4.615

    authors: Avidan MS,Harvey A,Chitkara N,Ponte J

    更新日期:1999-10-01 00:00:00

  • Comparative effect of thermal, mechanical, and electrical noxious stimuli on the electroencephalogram of the rat.

    abstract:BACKGROUND:Thermal, mechanical, and electrical stimuli are often used in acute pain studies and cause qualitatively different pain sensations. Yet, the comparative electroencephalogram (EEG) changes caused by these stimuli have not been studied. We hypothesized that because these stimuli cause different pain sensations...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/ael377

    authors: Murrell JC,Mitchinson SL,Waters D,Johnson CB

    更新日期:2007-03-01 00:00:00

  • Myoneural effects of pethidine and droperidol.

    abstract::In vitro experiments on the rat phrenic nerve-hemidiaphragm preparation, stimulated directly or indirectly with supramaximal impulses at 0.1 Hz revealed that pethidine in concentrations greater than 5 micrograms ml-1 caused a rapid increase of the twitch. This was maximal (60% increase during direct and 70% increase d...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/56.2.195

    authors: Boros M,Chaudhry IA,Nagashima H,Duncalf RM,Sherman EH,Foldes FF

    更新日期:1984-02-01 00:00:00

  • Nociceptin/orphanin FQ in inflammation and sepsis.

    abstract::Nociceptin/orphanin FQ, N/OFQ, and its receptor NOP represent a non-opioid branch of the opioid superfamily that were first studied for their effects on pain responses. Both N/OFQ and NOP are involved in a wide range of 'non-pain' responses including immunomodulation and cardiovascular control. There is now growing in...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aeq337

    authors: Serrano-Gomez A,Thompson JP,Lambert DG

    更新日期:2011-01-01 00:00:00

  • Fresh gas flow requirements during spontaneous ventilation: fresh gas flow to total ventilation ratio or ml kg-1 min-1?

    abstract::Both the performance of breathing systems and recommendations for the fresh gas flows to be used in patients breathing spontaneously can be expressed in ml kg-1 min-1 or fresh gas: total ventilation ratio (VF:VE). We have examined the relationship between these two descriptions. The data of 106 subjects (awake volunte...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/71.6.796

    authors: Soni N,Ooi R

    更新日期:1993-12-01 00:00:00