Influence of bolus doses of phenoperidine on intracranial pressure and systemic arterial pressure in traumatic coma.

abstract：:An animal model was established to study the toxic effects of hyperoxia and the consequent changes in intracellular antioxidant status. Superoxide dismutase, catalase and glutathione peroxidase activities were measured in erythrocytes, liver and lung, in addition to cellular glutathione concentrations and its associat...

journal_title：British journal of anaesthesia

authors： Webster NR,Toothill C,Cowen PN

更新日期：1987-06-01 00:00:00

abstract：:The circulating blood volume (CBV) of critically ill patients may be difficult to estimate on the basis of history and physical examination. The aim of this study was to evaluate the ability of seven clinical signs and central venous pressure (CVP) to predict CBV in critically ill patients; CBV was evaluated with the ...

journal_title：British journal of anaesthesia

authors： Stéphan F,Flahault A,Dieudonné N,Hollande J,Paillard F,Bonnet F

更新日期：2001-06-01 00:00:00

abstract：:We have studied post-tetanic count (PTC) and single twitch height at the onset of reflex movement to carinal stimulation after administration of vecuronium with five different types of anaesthesia. Seventy-five adult patients were allocated randomly to five groups of 15 patients each, to receive one of the following a...

journal_title：British journal of anaesthesia

authors： Saitoh Y,Kaneda K,Toyooka H,Amaha K

更新日期：1994-06-01 00:00:00

abstract：:On accout of its histamine releasing and ganglion blocking properties tubocurarine is known to have significant haemodynamic effects. Methylation of the compound produces metocurine and should decrease both histamine release and ganglionic blockade. The haemodynamic effects of these two compounds were compared in 10 m...

journal_title：British journal of anaesthesia

authors： Antonio RP,Philbin DM,Savarese JJ

更新日期：1979-11-01 00:00:00

abstract：:To determine if improved postoperative recovery in surgical inpatients receiving intraoperative therapeutic suggestions are applicable in an outpatient population, 70 consenting, unpremedicated adults undergoing elective outpatient hernia repair under general anaesthesia were allocated randomly to either a therapeutic...

journal_title：British journal of anaesthesia

authors： Lebovits AH,Twersky R,McEwan B

更新日期：1999-06-01 00:00:00

abstract：:In 40 patients anaesthetized with thiopentone, 66% nitrous oxide and 1% halothane, the effects of a single i.v. dose of nalbuphine 4.5, 8, 15, 25 or 50 mg/70 kg or morphine 3, 5, 10 or 17.5 mg/70 kg on total ventilation and end-tidal carbon dioxide concentration have been measured. Depression of respiration occurred w...

journal_title：British journal of anaesthesia

authors： Klepper ID,Rosen M,Vickers MD,Mapleson WW

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Clinicians frequently warn patients of discomfort before potentially painful procedures, despite the lack of evidence that such communications are helpful. We aimed to compare two communications (one with, and the other without, a warning of a 'sting') immediately before i.v. cannulation in order to measure ...

journal_title：British journal of anaesthesia

authors： Dutt-Gupta J,Bown T,Cyna AM

更新日期：2007-12-01 00:00:00

abstract：:Respiratory mass spectrometry and on-line computation were used to estimate lung volume in normal subjects by a rebreathing technique, using oxygen, nitrogen and argon as indicators. The computation had previously been tested in a numerical model. In real normal lungs, it performed well enough for practical purposes, ...

journal_title：British journal of anaesthesia

authors： Black AM,Scott IL,Hahn CE,Maynard P,Baker AB

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Postoperative delirium and cognitive decline are common in elderly surgical patients after non-cardiac surgery. Despite this prevalence and clinical importance, no specific aetiological factor has been identified for postoperative delirium and cognitive decline. In experimental setting in a rat model, nitrou...

journal_title：British journal of anaesthesia

authors： Leung JM,Sands LP,Vaurio LE,Wang Y

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:The efficacy of opioids typically decreases after long-term use owing to the development of tolerance. Glial activation and the upregulation of proinflammatory cytokines are related to the induction of tolerance. We investigated the effect of leukemia inhibitory factor (LIF) on morphine analgesia and toleran...

journal_title：British journal of anaesthesia

authors： Tu HJ,Kang KH,Ho SY,Liou HC,Liou HH,Lin CP,Fu WM

更新日期：2016-10-01 00:00:00

abstract：:We have studied the complications associated with three techniques used to maintain extradural analgesia in labour: midwife top-up doses of 0.25% bupivacaine 10 ml, continuous infusion of 0.125% bupivacaine 10 ml h-1 and patient-controlled extradural analgesia (PCEA) with self-administered 3-ml bolus doses of 0.25% bu...

journal_title：British journal of anaesthesia

authors： Tan S,Reid J,Thorburn J

更新日期：1994-11-01 00:00:00

abstract：:Experiments were performed on 14 anaesthetized, artifically ventilated dogs, in which efferent activity in the phrenic nerve was recorded and blood-gas tensions, arterial pH and core temperature were controlled. Doses of midazolam between 0.2 mg kg-1 and 2 mg kg-1 abolished phrenic nerve activity for periods between 3...

journal_title：British journal of anaesthesia

authors： Gordon G,Grundy EM,Al-Khudhairi D,Anderson DJ,Whitwam JG

更新日期：1984-10-01 00:00:00

abstract：:Some recipients of isolated, orthotopic lung transplants have now survived to leave hospital with greatly improved quality of life. Inevitably, the successful demonstration of the feasibility of these operations means that transplant centres throughout the world may wish to participate in a lung transplant programme. ...

journal_title：British journal of anaesthesia

authors： Conacher ID

更新日期：1988-10-01 00:00:00

abstract：:This study was designed to investigate if propofol produced cardiovascular effects by direct actions or by indirect actions secondary to depression of the central nervous system. Experiments were performed on chloralose anaesthetized dogs in which all neurogenic cardiovascular reflexes were abolished by bilateral vago...

journal_title：British journal of anaesthesia

authors： Goodchild CS,Serrao JM

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:This study was undertaken to compare the effects of general anaesthesia (GA) and spinal anaesthesia (SA) on the need for postoperative hospitalization and early postoperative comfort in patients undergoing fast-track total knee arthroplasty (TKA). METHODS:One hundred and twenty subjects were randomly alloca...

journal_title：British journal of anaesthesia

authors： Harsten A,Kehlet H,Toksvig-Larsen S

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Myocardial injury after noncardiac surgery is common, although the exact pathophysiology is unknown. It is plausible that hypotension after surgery is relevant for the development of myocardial injury. The authors evaluated whether low mean arterial pressures (MAPs) after surgery are related to an increased ...

journal_title：British journal of anaesthesia

authors： van Lier F,Wesdorp FHIM,Liem VGB,Potters JW,Grüne F,Boersma H,Stolker RJ,Hoeks SE

更新日期：2018-01-01 00:00:00

abstract：:This study tests the hypothesis that naloxone, but not its quarternary salt, naloxone methiodide (which does not enter the central nervous system), improves recovery from myocardial stunning in conscious dogs. Twenty dogs were chronically instrumented for measurement of heart rate, left atrial, aortic and left ventric...

journal_title：British journal of anaesthesia

authors： Weber TP,Stypmann J,Meissner A,Hartlage MG,Van Aken H,Rolf N

更新日期：2001-04-01 00:00:00

abstract：:We studied the elimination rate of nitrous oxide in 36 patients undergoing orthopaedic surgery. They were allocated randomly to one of six groups which differed in time of nitrous oxide exposure and mode of ventilation. In order to simulate recovery conditions, nitrous oxide administration was discontinued after 30, 6...

journal_title：British journal of anaesthesia

authors： Einarsson S,Stenqvist O,Bengtsson A,Houltz E,Bengtson JP

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Sepsis-induced organ failure is the major cause of death in critical care units, and is characterized by a massive dysregulated inflammatory response and oxidative stress. We investigated the effects of treatment with antioxidants that protect mitochondria (MitoQ, MitoE, or melatonin) in a rat model of lipop...

journal_title：British journal of anaesthesia

authors： Lowes DA,Webster NR,Murphy MP,Galley HF

更新日期：2013-03-01 00:00:00

abstract：:Volume loading with crystalloid solution results in more pronounced haemodilution in patients who develop arterial hypotension during induction of extradural anaesthesia than in those who remain normotensive. The aim of this study was to describe the time course of this increase in haemodilution. Heart rate, systolic ...

journal_title：British journal of anaesthesia

authors： Drobin D,Hahn RG

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Atelectasis is known to develop during anaesthesia and after operation atelectasis leads to impaired oxygenation. Lung recruitment manoeuvres, positive end-expiratory pressure (PEEP), and continuous positive airway pressure (CPAP) have been proposed for reduction of atelectasis but their benefits have not be...

journal_title：British journal of anaesthesia

authors： Lumb AB,Greenhill SJ,Simpson MP,Stewart J

更新日期：2010-05-01 00:00:00

abstract：:Cardiac rate and rhythm were compared in 60 patients having dental extractions under conventional general anaesthesia using halothane, enflurane or isoflurane to supplement nitrous oxide in oxygen. The incidence of arrhythmia was higher in the halothane group when compared with both the enflurane (P less than 0.05) an...

journal_title：British journal of anaesthesia

authors： Casson WR,Jones RM

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Echocardiography has been shown to positively impact on the management of the critically ill patient. However, many published studies have a significant bias towards inclusion of cardiothoracic patients. We present an audit of the impact of echocardiography on the management of patients in a district general...

journal_title：British journal of anaesthesia

authors： Orme RM,Oram MP,McKinstry CE

更新日期：2009-03-01 00:00:00

abstract：:We have evaluated the accuracy and reliability of the Paratrend 7 continuous blood-gas analyser in infants and small children under conditions of severe hypoxaemia admitted to the paediatric intensive care unit in the perioperative period with cyanotic congenital heart disease. PO2, PCO2 and pH (hydrogen ion concentra...

journal_title：British journal of anaesthesia

authors： Hatherill M,Tibby SM,Durward A,Rajah V,Murdoch IA

更新日期：1997-11-01 00:00:00

abstract：:We have tested the hypothesis that intradermal testing is a more effective method for determining the drug responsible for anaesthetic anaphylactic reactions than prick testing in 212 consecutive patients, aged more than 10 yr, referred to an anaesthetic allergy clinic over a 4-yr period. The study was a prospective, ...

journal_title：British journal of anaesthesia

authors： Fisher MM,Bowey CJ

更新日期：1997-07-01 00:00:00

abstract：Background.:Compromised tissue oxygenation is one of the root causes of dysfunction of various organs and postoperative complications. Oxygenation of different tissue beds may follow different patterns of change during physiological derangement. Methods.:Patients undergoing elective major posterior spine surgery parti...

journal_title：British journal of anaesthesia

authors： Meng L,Xiao J,Gudelunas K,Yu Z,Zhong Z,Hu X

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:As 6% hydroxyethyl starch (HES) 130/0.40 or 130/0.42 can originate from different vegetable sources, they might have different clinical effects. The purpose of this prospective, randomized, double-blind controlled trial was to compare two balanced tetrastarch solutions, one maize-derived and one potato-deriv...

journal_title：British journal of anaesthesia

authors： Joosten A,Tircoveanu R,Arend S,Wauthy P,Gottignies P,Van der Linden P

更新日期：2016-10-01 00:00:00

abstract：:Seventy-six Chinese patients aged between 15 and 30 yr, undergoing 3rd molar extraction, were randomly allocated to two groups. One group received halothane and the other isoflurane. The incidence of arrhythmia during surgery under anaesthesia with isoflurane was significantly less than with halothane. Sinus tachycard...

journal_title：British journal of anaesthesia

authors： Rodrigo MR,Moles TM,Lee PK

更新日期：1986-04-01 00:00:00

abstract：:Studies with an emulsion formulation of ICI 35 868 (2,6- diisopropylphenol ) indicate that this new formulation has anaesthetic properties in rats and mice, and haemodynamic effects in the mini-pig which are similar to those of the previously available Cremophor formulation. Administration of the emulsion formulation ...

journal_title：British journal of anaesthesia

authors： Glen JB,Hunter SC

更新日期：1984-06-01 00:00:00

abstract：:In obstetric patients undergoing postpartum tubal ligation, we found that metoclopramide produced dose-dependent prolongation of suxamethonium-induced neuromuscular block. Mean block times after suxamethonium 1 mg kg-1 were 8.0 min, 9.83 min and 12.45 min for control and metoclopramide 10 mg and metoclopramide 20 mg g...

journal_title：British journal of anaesthesia

authors： Kao YJ,Tellez J,Turner DR

更新日期：1990-08-01 00:00:00