Impact of echocardiography on patient management in the intensive care unit: an audit of district general hospital practice.

abstract：BACKGROUND:Using a carrageenan inflammation rat model, we evaluated two experimental approaches to prolong sciatic nerve block on contralateral hyperalgesia. Method. We performed ipsilateral sciatic nerve block on the inflamed hind paw with bupivacaine-loaded microspheres suspended in dexamethasone (bupivacaine 12.5 mg...

journal_title：British journal of anaesthesia

authors： Estebe JP,Gentili ME,Le Corre P,Leduc C,Moulinoux JP,Ecoffey C

更新日期：2004-11-01 00:00:00

abstract：:Serum concentrations of the cytokine, interleukin-6 (IL-6), increase after surgical trauma. IL-6 mediates the synthesis of acute phase proteins and stimulates secretion of pituitary hormones. We have examined the time course of circulating IL-6, and cortisol and growth hormone responses in patients undergoing hysterec...

journal_title：British journal of anaesthesia

authors： Moore CM,Desborough JP,Powell H,Burrin JM,Hall GM

更新日期：1994-03-01 00:00:00

abstract：:Zomepirac 100 mg and dihydrocodeine 30 mg were compared with placebo in a controlled randomized, double-blind, single-dose postoperative study. Patients continued to receive either zomepirac or dihydrocodeine for pain relief for 5 days at home in a double-blind study, being allowed to titrate the consumption of tablet...

journal_title：British journal of anaesthesia

authors： McQuay HJ,Bullingham RE,Moore RA,Carroll D,Evans PJ,O'Sullivan G,Collin J,Lloyd JW

更新日期：1985-04-01 00:00:00

abstract：:The minimum local analgesic concentration (MLAC) of bupivacaine in labour is defined as the effective concentration in 50% of subjects (EC50). We have used the technique of double-blinded sequential allocation to quantify the bupivacaine sparing effect of the addition of four different doses of extradural fentanyl in ...

journal_title：British journal of anaesthesia

authors： Lyons G,Columb M,Hawthorne L,Dresner M

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Intraneural injection of local anaesthetic agents carries a risk of neurological complications. Early detection of intraneural needle-tip position is very important in the initial phase of injection. Ultrasound (US) characteristics for real-time detection of intraneural injections have been described, but on...

journal_title：British journal of anaesthesia

authors： Moayeri N,Krediet AC,Welleweerd JC,Bleys RL,Groen GJ

更新日期：2012-09-01 00:00:00

abstract：:In 105 patients undergoing day-case surgery recovery of consciousness was significantly faster after enfluane compared with halothane anaesthesia. There was no difference in postoperative morbidity between the two anaesthetic groups. ...

journal_title：British journal of anaesthesia

authors： Stanford BJ,Plantevin OM,Gilbert JR

更新日期：1979-12-01 00:00:00

abstract：:A randomized, double-blind study of 40 women was performed to compare patient controlled anaesthesia (PCA) morphine requirements after spinal anaesthesia for elective Caesarean section. The women received 0.2 mg of either morphine or diamorphine mixed with 0.5% bupivacaine in 8% dextrose. There were no significant dif...

journal_title：British journal of anaesthesia

authors： Husaini SW,Russell IF

更新日期：1998-08-01 00:00:00

abstract：:We have studied the effect of clonidine, dexmedetomidine and morphine on gastric emptying and gastrointestinal transit in the rat. In one group, each agonist was injected i.p. in 6-12 male Wistar rats. In another group of rats, yohimbine, naloxone or saline was injected with an agonist. At 30 min, radiolabelled saline...

journal_title：British journal of anaesthesia

authors： Asai T,Mapleson WW,Power I

更新日期：1997-03-01 00:00:00

abstract：:Quality of recovery after anaesthesia is an important measure of the early postoperative health status of patients. We attempted to develop a valid, reliable and responsive measure of quality of recovery after anaesthesia and surgery. We studied 160 patients and asked them to rate postoperative recovery using three me...

journal_title：British journal of anaesthesia

authors： Myles PS,Weitkamp B,Jones K,Melick J,Hensen S

更新日期：2000-01-01 00:00:00

abstract：:Magnesium inhibits the release of acetylcholine from the motor nerve terminal and thus potentiates the action of the non-depolarizing neuromuscular blocking drugs. We have examined the possibility that this effect might enhance the speed of onset of non-depolarizing block with pancuronium. Following the administration...

journal_title：British journal of anaesthesia

authors： James MF,Schenk PA,van der Veen BW

更新日期：1991-02-01 00:00:00

abstract：:A new anaesthetic gas scavenging system is described. The resistance of the system appears to be low. When input gas flow rate in the system was zero or 150 litre min-1, misuse of the system produced pressure changes at its collecting points of 26 Pa subatmospheric and 630 Pa above atmospheric pressure, respectively. ...

journal_title：British journal of anaesthesia

authors： Mostafa SM,Natrajan KM

更新日期：1983-07-01 00:00:00

abstract：:Day-case anaesthesia requires rapidly eliminated anaesthetics which are relatively expensive. This multinational, multicentre European study assessed the relative costs of propofol or sevoflurane anaesthesia in 211 patients. Anaesthesia was induced and maintained with propofol in group 1, with propofol and sevoflurane...

journal_title：British journal of anaesthesia

authors： Smith I,Terhoeve PA,Hennart D,Feiss P,Harmer M,Pourriat JL,Johnson IA

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:We measured the effect of two weight adjusted i.v. doses (0.2 mg per 70 kg and 0.4 mg per 70 kg) of the potent opioid buprenorphine on analgesia and respiratory depression in healthy volunteers. The aim of the study was to compare buprenorphine's behaviour with respect to the occurrence of ceiling (or appare...

journal_title：British journal of anaesthesia

authors： Dahan A,Yassen A,Romberg R,Sarton E,Teppema L,Olofsen E,Danhof M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The cuff pressures may be different in oesophageal and tracheal intubations. We conducted a study to evaluate if cuff pressures of endotracheal tubes (ETTs) could provide information to distinguish tracheal or oesophageal intubations in a pig trachea-oesophagus model. METHODS:In each preparation of pig trac...

journal_title：British journal of anaesthesia

authors： Lin HJ,Chen KT,Foo NP,Hsu CC,Guo HR

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Serum vascular endothelial growth factor-C (VEGF-C), transforming growth factor-β (TGF-β), and interleukin (IL)-6 promote angiogenesis and metastases in colon cancer. We hypothesized that patients who received propofol-epidural anaesthesia (PEA) would exhibit decreases in VEGF-C, TGF-β, and IL-6 and an incre...

journal_title：British journal of anaesthesia

authors： Xu YJ,Chen WK,Zhu Y,Wang SL,Miao CH

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for...

journal_title：British journal of anaesthesia

authors： Zuppa AF,Nicolson SC,Wilder NS,Ibla JC,Gottlieb EA,Burns KM,Stylianou M,Trachtenberg F,Ni H,Skeen TH,Andropoulos DB,Pediatric Heart Network Investigators.

更新日期：2019-12-01 00:00:00

abstract：:Fentanyl or alfentanil, in doses approximating to those used in clinical practice, was added to the priming fluid of an extracorporeal circuit before the institution of cardiopulmonary bypass (CPB). The concentrations of both drugs in the priming fluid were measured over a 20-min period. The concentration of fentanyl ...

journal_title：British journal of anaesthesia

authors： Skacel M,Knott C,Reynolds F,Aps C

更新日期：1986-09-01 00:00:00

abstract：:We describe a 25 mg intrathecal morphine overdose during a combined spinal-epidural block for a Caesarean delivery. Naloxone infusion (5.24 mg over 24 h) was started prior to the patient becoming symptomatic and almost immediately after the overdose. Invasive therapeutics such as mechanical ventilation were avoided. ...

journal_title：British journal of anaesthesia

authors： Cannesson M,Nargues N,Bryssine B,Debon R,Boselli E,Chassard D

更新日期：2002-12-01 00:00:00

abstract：:We report a case of improved cardiopulmonary exercise (CPX) test outcomes measured 48 h after initial CPX testing and immediately after alterations were made to the settings of a dual chamber, dual sensing pacemaker with exercise detection. The changes allowed successful abdominal surgery to be completed. ...

journal_title：British journal of anaesthesia

authors： Bolsin S,Colson M,Ridley D,Ward C

更新日期：2014-06-01 00:00:00

abstract：:We have examined the effects of morphine in auricular myocardium from non-failing and failing human hearts. In both preparations morphine induced inhibition. These responses were not antagonized by naloxone. Comparison of mean IC30 values obtained in non-failing (3.9 (SEM 0.2) x 10(-8) mol litre-1) and failing (5010 (...

journal_title：British journal of anaesthesia

authors： Llobel F,Laorden ML

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Even mild perioperative hypothermia is associated with several severe adverse effects. Resistive heating has possible advantages compared with other active warming systems because it can heat several fields independently. To assess this new warming system, we measured core temperature in patients during surg...

journal_title：British journal of anaesthesia

authors： Matsuzaki Y,Matsukawa T,Ohki K,Yamamoto Y,Nakamura M,Oshibuchi T

更新日期：2003-05-01 00:00:00

abstract：:Fast inactivation of sodium channel function is modified by anaesthetics. Its quantitative contribution to the overall anaesthetic effect is assessed by removing the fast inactivation mechanism enzymatically. Sodium channels from human brain cortex were incorporated into planar lipid bilayers. After incorporation, cha...

journal_title：British journal of anaesthesia

authors： Wartenberg HC,Urban BW,Duch DS

更新日期：1999-01-01 00:00:00

abstract：:During resection of a Wilms' tumour in a 10-year-old girl, sudden bradycardia, hypotension and cyanosis developed, leading to cardiac arrest. It was thought that part of the tumour had caused a pulmonary embolus. After prompt resuscitation, cardiopulmonary bypass surgery was started within 20 min. At operation the lef...

journal_title：British journal of anaesthesia

authors： Akyön MG,Arslan G

更新日期：1981-08-01 00:00:00

abstract：:A blood-gas study of the respiratory effects of sodium nitroprusside during anaesthesia has shown a marked reduction in PaO2 when the drug was administered. After nitroprusside PaO2 returned to the previous values. It is suggested that the reduction in PaO2 is a result of an increased scatter of ventilation/perfusion ...

journal_title：British journal of anaesthesia

authors： Wildsmith JA,Drummond GB,MacRae WR

更新日期：1975-11-01 00:00:00

abstract：:The effects of the inhalation of 50% nitrous oxide on somatosensory evoked potentials during a fentanyl-oxygen anaesthetic technique for central nervous system surgery were evaluated. The latency and amplitude of the first cortical wave were obtained using conventional somatosensory techniques with median or posterior...

journal_title：British journal of anaesthesia

authors： Sloan TB,Koht A

更新日期：1985-09-01 00:00:00

abstract：:This study was designed to investigate if propofol produced cardiovascular effects by direct actions or by indirect actions secondary to depression of the central nervous system. Experiments were performed on chloralose anaesthetized dogs in which all neurogenic cardiovascular reflexes were abolished by bilateral vago...

journal_title：British journal of anaesthesia

authors： Goodchild CS,Serrao JM

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The AirWay Scope (AWS) is a fibreoptic device that allows for intubation without alignment of the oral, pharyngeal, and tracheal axes. It may be useful for patients with an unstable cervical-spine (C-spine) or when C-spine movement is undesirable. This study was conducted to fluoroscopically evaluate upper C...

journal_title：British journal of anaesthesia

authors： Maruyama K,Yamada T,Kawakami R,Hara K

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The significance of IgE antibodies to neuromuscular blocking agent (NMBA)-induced anaphylactic reactions during anaesthesia is unclear. We investigated the relevance of IgE to rocuronium using an in vitro technique. METHODS:Serum samples from 61 patients with anaphylactic reactions during anaesthesia were i...

journal_title：British journal of anaesthesia

authors： Aalberse RC,Kleine Budde I,Mulder M,Stapel SO,Paulij W,Leynadier F,Hollmann MW

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Target-controlled infusion (TCI) systems use pharmacokinetic (PK) models to predict the drug infusion rates necessary to achieve a desired target plasma or effect-site concentration. As new PK models are developed and implemented in TCI systems, there can be uncertainty as to which target concentrations are ...

journal_title：British journal of anaesthesia

authors： Eleveld DJ,Colin P,Absalom AR,Struys MMRF

更新日期：2020-10-01 00:00:00

abstract：:Dysregulation of the immuno-inflammatory response, as seen in sepsis, may culminate in host cell and organ damage. Lipopolysaccharide from Gram-negative bacterial cell walls induces gene activation and subsequent inflammatory mediator expression. Gene activation is regulated by a number of transcription factors at the...

journal_title：British journal of anaesthesia

authors： Macdonald J,Galley HF,Webster NR

更新日期：2003-02-01 00:00:00