Cardiac rate and rhythm during anaesthesia for dental extraction. A comparison of halothane, enflurane and isoflurane.

abstract：:We have determined the influence of 0.1 minimum alveolar concentration (MAC) of sevoflurane on ventilation, the acute ventilatory response to a step change in end-tidal carbon dioxide and the ventilatory response to sustained hypercapnia in 10 healthy adult volunteers. Subjects undertook a preliminary 10-min period of...

journal_title：British journal of anaesthesia

authors： Pandit JJ,Manning-Fox J,Dorrington KL,Robbins PA

更新日期：1999-08-01 00:00:00

abstract：:The haemodynamic effects of diltiazem were studied in six dogs during fentanyl-nitrous oxide (in oxygen) anaesthesia. A bolus of diltiazem 300 micrograms kg-1 was given, followed by infusions at 30, 60 and 90 micrograms kg-1 min-1 which produced plasma diltiazem concentrations of 392 +/- 30, 908 +/- 54 and 1483 +/- 13...

journal_title：British journal of anaesthesia

authors： Griffin RM,Dimich I,Jurado R,Kaplan JA

更新日期：1988-05-01 00:00:00

abstract：:Volatile anaesthetics have been shown to have direct relaxant effects on airway smooth muscle. We have examined the effects of 0.9, 1.9, and 2.8 dog MAC of desflurane and halothane on isolated proximal and distal canine airways precontracted with acetylcholine. The proximal and distal airway smooth muscle relaxed with...

journal_title：British journal of anaesthesia

authors： Mazzeo AJ,Cheng EY,Bosnjak ZJ,Coon RL,Kampine JP

更新日期：1996-06-01 00:00:00

abstract：:Carotid endarterectomy is commonly conducted under regional (deep, superficial, intermediate, or combined) cervical plexus block, but it is not known if complication rates differ. We conducted a systematic review of published papers to assess the complication rate associated with superficial (or intermediate) and deep...

journal_title：British journal of anaesthesia

authors： Pandit JJ,Satya-Krishna R,Gration P

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:One-lung ventilation (OLV) increases mechanical stress in the lung and affects ventilation and perfusion (V, Q). There are no data on the effects of OLV on postoperative V/Q matching. Thus, this controlled study evaluates the influence of OLV on V/Q distribution in a pig model using a gamma camera technique ...

journal_title：British journal of anaesthesia

authors： Kozian A,Schilling T,Fredén F,Maripuu E,Röcken C,Strang C,Hachenberg T,Hedenstierna G

更新日期：2008-04-01 00:00:00

abstract：:We have examined the role of gamma-aminobutyric acid (GABA) neurones in propofol anaesthesia in mice using the righting reflex. Propofol i.p. increased the percentage of loss of the righting reflex in a dose-dependent manner with an ED50 value of 140 (95% confidence limits 123-160) mg kg-1 (n = 40; eight animals per d...

journal_title：British journal of anaesthesia

authors： Irifune M,Sugimura M,Takarada T,Maeoka K,Shimizu Y,Dohi T,Nishikawa T,Kawahara M

更新日期：1999-10-01 00:00:00

abstract：Background:Experimental studies suggest that mechanical cell washing to remove pro-inflammatory components that accumulate in the supernatant of stored donor red blood cells (RBCs) might reduce inflammation and organ injury in transfused patients. Methods:Cardiac surgery patients at increased risk of large-volume RBC ...

journal_title：British journal of anaesthesia

authors： Wozniak MJ,Sullo N,Qureshi S,Dott W,Cardigan R,Wiltshire M,Morris T,Nath M,Bittar N,Bhudia SK,Kumar T,Goodall AH,Murphy GJ

更新日期：2017-05-01 00:00:00

abstract：:Most human phenotypic characteristics are determined by the interplay of environmental factors (whether external, or related to the internal milieu) with the unique genetic attributes of the individual. The same is true for predisposition to and outcome from most disease states, with acute brain injury being no except...

journal_title：British journal of anaesthesia

authors： Wilson M,Montgomery H

更新日期：2007-07-01 00:00:00

abstract：:We report a case of lumbar radiculopathy after zygapophyseal joint injections for chronic low back pain. The management of the patient and potential causes for the radiculopathy are discussed. The case acts as a reminder that the spinal nerve roots should be considered when performing intra-articular facet joint injec...

journal_title：British journal of anaesthesia

authors： Sehgal A,Valentine JM

更新日期：2007-09-01 00:00:00

abstract：Background:Blood lactate is a strong predictor of mortality, and repeated blood lactate assays are recommended during surgery in high-risk patients. We hypothesized that the use of intravascular microdialysis incorporated in a central venous catheter would be interchangeable with the reference blood gas technique to mo...

journal_title：British journal of anaesthesia

authors： Gouëzel C,Lorne E,Bonnet V,Fradin S,Saplacan V,Gérard JL,Hanouz JL,Fellahi JL,Fischer MO,FHT (French Hemodynamic Team).

更新日期：2017-12-01 00:00:00

abstract：:General anaesthesia for emergency surgery in a pressurized habitat is likely to involve the use of i.v. agents. The anaesthetic property of such agents is known to be antagonized by pressure, but the effect on their duration of action is not easily predicted. The recovery of mice from a single i.v. dose of Althesin, k...

journal_title：British journal of anaesthesia

authors： Shearer AJ,Ross JA,Manson HJ

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Growing evidences indicate that inhalational anaesthetics can enhance the growth and malignant potential of tumour cells and may affect tumour recurrence after surgery. Tumour stem cells play a vital role in tumour recurrence. This study investigates the effect of sevoflurane on glioma stem cells (GSCs) in v...

journal_title：British journal of anaesthesia

authors： Shi QY,Zhang SJ,Liu L,Chen QS,Yu LN,Zhang FJ,Yan M

更新日期：2015-05-01 00:00:00

abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief, Professor Hugh Hemmings, based on the recommendations of Justus-Liebig-University Giessen f...

journal_title：British journal of anaesthesia

authors： Boldt J

更新日期：2020-09-01 00:00:00

abstract：:We studied the interactive effect of dexmedetomidine and morphine on gastric emptying and gastrointestinal transit in the rat. In one group of rats, to examine the interactive effect on gastrointestinal transit, the two drugs were injected i.p. in a fixed ratio (30: 1)--that of their ED50 values--in six doses (0.062-1...

journal_title：British journal of anaesthesia

authors： Asai T,Mapleson WW,Power I

更新日期：1998-01-01 00:00:00

abstract：:We have studied the efficacy of preoxygenation using the Triservice Anaesthetic Apparatus (TSA) in healthy patients and found it to be unsatisfactory. An alternative technique suitable for field use was explored. The Mapleson D system (Bain) was found to be suitable for preoxygenation with a fresh gas flow of only 4 l...

journal_title：British journal of anaesthesia

authors： Lowe DM,McFadzean W

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...

journal_title：British journal of anaesthesia

authors： Chen A,Elia N,Dunaiceva J,Rudiger A,Walder B,Bollen Pinto B

更新日期：2020-06-01 00:00:00

abstract：:In a controlled, randomized study, we evaluated duration of neuromuscular block in 80 patients undergoing routine abdominal surgery. Forty patients were aged 18-50 yr (control group) and 40 patients were more than 65 yr (elderly group). All patients had normal plasma creatinine concentrations. After induction of anaes...

journal_title：British journal of anaesthesia

authors： Slavov V,Khalil M,Merle JC,Agostini MM,Ruggier R,Duvaldestin P

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Serum vascular endothelial growth factor-C (VEGF-C), transforming growth factor-β (TGF-β), and interleukin (IL)-6 promote angiogenesis and metastases in colon cancer. We hypothesized that patients who received propofol-epidural anaesthesia (PEA) would exhibit decreases in VEGF-C, TGF-β, and IL-6 and an incre...

journal_title：British journal of anaesthesia

authors： Xu YJ,Chen WK,Zhu Y,Wang SL,Miao CH

更新日期：2014-07-01 00:00:00

abstract：:Five hundred and seventeen women in labour receiving extradural analgesia, using bupivacaine plain solution, were randomly allocated to one of three groups. Group A received 6-8ml of 0.5% solution, group B 10-14ml of 0.25% solution, and group C 6-8 ml of 0.25% solution. Spontaneous delivery occurred in 31.7% of patien...

journal_title：British journal of anaesthesia

authors： Thorburn J,Moir DD

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Propofol and sevoflurane are suitable agents for maintenance of anaesthesia during neurosurgical procedures. We have prospectively compared these agents in combination with the short-acting opioid, remifentanil. METHODS:Fifty unpremedicated patients undergoing elective craniotomy received remifentanil 1 mic...

journal_title：British journal of anaesthesia

authors： Sneyd JR,Andrews CJ,Tsubokawa T

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:It is believed that the severely disturbed night-time sleep architecture after surgery is associated with increased cardiovascular morbidity with rebound of rapid eye movement (REM). The daytime sleep pattern of patients after major general surgery has not been investigated before. We decided to study the ci...

journal_title：British journal of anaesthesia

authors： Gögenur I,Wildschiøtz G,Rosenberg J

更新日期：2008-01-01 00:00:00

abstract：:This is the report of a 55-yr-old female who developed severe myotonia and dystonia after general anaesthesia. Before starting on gabapentin therapy for a neuropathic pain condition, she had undergone numerous uneventful general anaesthetics. Since receiving treatment with gabapentin, she has experienced severe moveme...

journal_title：British journal of anaesthesia

authors： Allford MA

更新日期：2007-08-01 00:00:00

abstract：:Dysregulation of the immuno-inflammatory response, as seen in sepsis, may culminate in host cell and organ damage. Lipopolysaccharide from Gram-negative bacterial cell walls induces gene activation and subsequent inflammatory mediator expression. Gene activation is regulated by a number of transcription factors at the...

journal_title：British journal of anaesthesia

authors： Macdonald J,Galley HF,Webster NR

更新日期：2003-02-01 00:00:00

abstract：:We have investigated the incidence of regurgitation of gastric contents during general anaesthesia administered via a laryngeal mask airway (LMA) or face mask and Guedel airway in 56 patients with no risk factors for regurgitation. Patients swallowed a gelatin capsule containing methylene blue 10 min before induction ...

journal_title：British journal of anaesthesia

authors： Barker P,Langton JA,Murphy PJ,Rowbotham DJ

更新日期：1992-09-01 00:00:00

abstract：:We have studied the plasma concentrations (Cp) and pharmacokinetics of sufentanil injected i.v. (IVS), intradurally (IS) or extradurally (ES) under general anaesthesia in 31 patients undergoing major abdominal surgery. Sufentanil appeared in plasma very rapidly and Cpmax was also attained rapidly after both extradural...

journal_title：British journal of anaesthesia

authors： Ionescu TI,Taverne RH,Houweling PL,Drost RH,Nuijten S,Van Rossum J

更新日期：1991-04-01 00:00:00

abstract：:Magnesium inhibits the release of acetylcholine from the motor nerve terminal and thus potentiates the action of the non-depolarizing neuromuscular blocking drugs. We have examined the possibility that this effect might enhance the speed of onset of non-depolarizing block with pancuronium. Following the administration...

journal_title：British journal of anaesthesia

authors： James MF,Schenk PA,van der Veen BW

更新日期：1991-02-01 00:00:00

abstract：:Since 1972, 367 patients with chronic low-back pain have been treated by electrical stimulation (e.s.). Patients with herniated disc lesions and spondylitis and allied conditions were included. Following e.s. 75-100% pain relief was obtained by 53% of the patients 50% pain relief by 27% and there was no improvement in...

journal_title：British journal of anaesthesia

authors： Rutkowski B,Niedzialkowska T,Otto J

更新日期：1977-06-01 00:00:00

abstract：:Respiratory obstruction has been reported as a complication of carotid endarterectomy; the causes include traumatic mucosal oedema, direct tracheal compression by haematoma and oedema secondary to lymphatic and venous congestion. We report four cases of acute respiratory obstruction complicating carotid endarterectomy...

journal_title：British journal of anaesthesia

authors： Munro FJ,Makin AP,Reid J

更新日期：1996-01-01 00:00:00

abstract：Background:. Missense variants in the ryanodine receptor 1 gene ( RYR1 ) are associated with malignant hyperthermia but only a minority of these have met the criteria for use in predictive DNA diagnosis. We examined the utility of a simplified method of segregation analysis and a functional assay for determining the pa...

journal_title：British journal of anaesthesia

authors： Merritt A,Booms P,Shaw MA,Miller DM,Daly C,Bilmen JG,Stowell KM,Allen PD,Steele DS,Hopkins PM

更新日期：2017-04-01 00:00:00

abstract：:This paper describes the use of solenoid valves for the production of binary gas mixtures. The system is controlled by a microprocessor and is capable of delivering accurate flows and concentrations of gases over the ranges commonly used in anaesthesia. Since the flow produced by the valves is pulsatile, a system for ...

journal_title：British journal of anaesthesia

authors： Palayiwa E,Hahn CE,Sugg BR,Lindsay-Scott D,Tyrrell PJ

更新日期：1986-09-01 00:00:00