Differential B and C fibre block by an amide- and an ester-linked local anaesthetic.

abstract：:This communication presents evidence in support of a neuropathic basis for the myopathy associated with malignant hyperpyrexia (MH). Muscle from MH susceptible individuals showed a reduced calcium uptake by the sarcoplasmic reticulum. There was a reduced concentration of phosphocreatine and ATP and an increased concen...

journal_title：British journal of anaesthesia

authors： Isaacs H,Heffron JJ

更新日期：1975-04-01 00:00:00

abstract：:The use of di-isopropyl phenol (Diprivan) for induction of anaesthesia was assessed in doses ranging from 1 to 3 mg kg-1. With less than 1.75mg kg-1 not all patients were anaesthetized; 2.0 mg kg-1 appeared to be a satisfactory induction dose. Involuntary muscle movement, cough and hiccup at induction were rare with a...

journal_title：British journal of anaesthesia

authors： Briggs LP,Clarke RS,Dundee JW,Moore J,Bahar M,Wright PJ

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:The inhibitory effect of anaesthetic agents on hypoxic pulmonary vasoconstriction may depend upon their dose, especially when using a volatile agent. The aim of this randomized open study was to compare the effects of sevoflurane and propofol, as primary anaesthetic agents, on oxygenation during one-lung ven...

journal_title：British journal of anaesthesia

authors： Pruszkowski O,Dalibon N,Moutafis M,Jugan E,Law-Koune JD,Laloë PA,Fischler M

更新日期：2007-04-01 00:00:00

abstract：:We have investigated 60 patients in a prospective double-blind, placebo-controlled study to assess the efficacy of EMLA (Eutectic Mixture of Local Anaesthetics) cream to provide analgesia during extracorporeal shock wave lithotripsy (ESWL) with a second generation lithotriptor. Before operation, EMLA or placebo cream ...

journal_title：British journal of anaesthesia

authors： McDonald PF,Berry AM

更新日期：1992-10-01 00:00:00

abstract：:An investigation was carried out into the relationship between the inflation pressures of normally compliant lungs and the airways pressure necessary to produce the insufflation of gas to the stomach. This relationship was examined during manual ventilation with a mask, using a rapid sequence induction technique. In t...

journal_title：British journal of anaesthesia

authors： Lawes EG,Campbell I,Mercer D

更新日期：1987-03-01 00:00:00

abstract：:We studied 325 patients undergoing elective noncardiac surgery who had preoperative ambulatory ECG monitoring performed for a duration of 5130 h (range 8-24 h; mean 15.8 h). Sixty-four subjects (20%) had one or more episodes of ST segment depression consistent with myocardial ischaemia. Of all preoperative cardiovascu...

journal_title：British journal of anaesthesia

authors： Allman KG,Muir A,Howell SJ,Hemming AE,Sear JW,Foëx P

更新日期：1994-11-01 00:00:00

abstract：:The effects of the inhalation of 50% nitrous oxide on somatosensory evoked potentials during a fentanyl-oxygen anaesthetic technique for central nervous system surgery were evaluated. The latency and amplitude of the first cortical wave were obtained using conventional somatosensory techniques with median or posterior...

journal_title：British journal of anaesthesia

authors： Sloan TB,Koht A

更新日期：1985-09-01 00:00:00

abstract：:A new type of intra-arterial oxygen electrode was evaluated. In 14 patients, undergoing one-lung ventilation for thoracic surgery, the electrode was inserted into the radial artery and changes in PaO2 were recorded continuously. Methods of improving PaO2 during one-lung ventilation were demonstrated. ...

journal_title：British journal of anaesthesia

authors： Armstrong RF,Hutchinson JM,Lincoln C,Ingram D,Soutter L

更新日期：1976-10-01 00:00:00

abstract：:Closed-loop control of neuromuscular blockade, using a semi-continuous infusion of vecuronium, is described. In 28 patients, the average neuromuscular transmission was between 13 and 17% of control. Requirements for vecuronium averaged 1.1 micrograms kg-1 min-1 (0.8-1.5 micrograms kg-1 min-1), being in the same range ...

journal_title：British journal of anaesthesia

authors： de Vries JW,Ros HH,Booij LH

更新日期：1986-10-01 00:00:00

abstract：:A 72-yr-old patient was to undergo a left lumbar plexus block by the posterior approach to achieve postoperative analgesia after hip replacement. The block failed after three unsuccessful attempts to identify nerve structures and a fascia iliaca compartment block was performed. Postoperatively the patient received eno...

journal_title：British journal of anaesthesia

authors： Aveline C,Bonnet F

更新日期：2004-10-01 00:00:00

abstract：:The central venous catheter (CVC) is associated with numerous complications more so during the process of insertion. We report for the first time how an indwelling catheter was entrapped by a replacement catheter on the same side, after being speared by the introducer needle and guidewire. The diagnosis was made when ...

journal_title：British journal of anaesthesia

authors： Dhanani J,Senthuran S,Olivotto R,Boots RJ,Lipman J

更新日期：2007-01-01 00:00:00

abstract：:We studied 52 adults undergoing elective craniotomy, allocated randomly to one of three opioid treatments: alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 until dural closure (group Alf.); alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 for 2 h, then remifentanil 0.25 microgra...

journal_title：British journal of anaesthesia

authors： Sneyd JR,Whaley A,Dimpel HL,Andrews CJ

更新日期：1998-09-01 00:00:00

abstract：:We have undertaken a prospective, randomized study to determine the incidence of postoperative nausea and vomiting during intensive care stay after cardiac surgery, and to study the effect of addition of droperidol to an infusion of morphine used for postoperative analgesia. Data from 398 patients were examined. The u...

journal_title：British journal of anaesthesia

authors： Grebenik CR,Allman C

更新日期：1996-09-01 00:00:00

abstract：:The effects of doxacurium chloride, a new long-acting non-depolarizing neuromuscular blocking drug, on cardiac performance were studied in 45 patients undergoing high-dose fentanyl-diazepam-oxygen anaesthesia for cardiac surgery. Data were collected at baseline (10 min after tracheal intubation), and at 2, 5 and 10 mi...

journal_title：British journal of anaesthesia

authors： Reich DL,Konstadt SN,Thys DM,Hillel Z,Raymond R,Kaplan JA

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Microvascular dysfunction is considered to play an important pathophysiological role in sepsis. We addressed the hypothesis that macrovascular and microvascular flow are uncoupled in early sepsis, using a rodent model with well-characterized haemodynamic and biochemical markers of severity and subsequent mor...

journal_title：British journal of anaesthesia

authors： Dyson A,Cone S,Singer M,Ackland GL

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Forty-eight ASA I-II patients undergoing total abdominal hysterectomy (TAH) were studied in a double blind, randomized placebo controlled trial of parecoxib for postoperative analgesia. METHODS:All patients were given propofol 2-4 mg kg(-1) i.v., a non-depolarizing muscle relaxant, morphine 10 mg i.v. and p...

journal_title：British journal of anaesthesia

authors： Ng A,Smith G,Davidson AC

更新日期：2003-06-01 00:00:00

abstract：:We have compared deep body temperature (DBT) measured at the forehead with the core temperatures of the nasopharynx, oesophagus and rectum during the warming phase of cardiopulmonary bypass (CPB) (moderate hypothermia of 26.7-29.6 degrees C) in 12 patients. DBT was measured transcutaneously by an insulated thermistor ...

journal_title：British journal of anaesthesia

authors： Sakuragi T,Mukai M,Dan K

更新日期：1993-10-01 00:00:00

abstract：:Alfentanil 700 micrograms and fentanyl 100 micrograms were compared as anaesthetic adjuvants in 90 patients undergoing short duration gynaecological procedures. The results show that, at the chosen dose ratio, alfentanil causes a higher frequency of post-induction apnoea, but thereafter the respiratory effects of the ...

journal_title：British journal of anaesthesia

authors： Hull CJ,Jacobson L

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:ROTEM(®)/TEG(®) (rotational thromboelastometry) assays appear to be useful for the treatment of bleeding trauma patients. However, data on the prevalence and impact of abnormal ROTEM(®) assays are scarce. METHODS:This is a prospective cohort study of blunt trauma patients (Injury Severity Score ≥15 or Glasg...

journal_title：British journal of anaesthesia

authors： Tauber H,Innerhofer P,Breitkopf R,Westermann I,Beer R,El Attal R,Strasak A,Mittermayr M

更新日期：2011-09-01 00:00:00

abstract：:We report the anaesthetic management of a male neonate with congenital cyst adenoid malformation (CCAM) of the lung who underwent thoracotomy for resection of CCAM 24 h after birth and again at 24 days. The initial operation involved a 10-day admission to a paediatric intensive care unit (PICU) requiring ventilation, ...

journal_title：British journal of anaesthesia

authors： Guruswamy V,Roberts S,Arnold P,Potter F

更新日期：2005-08-01 00:00:00

abstract：:We have studied the plasma concentrations (Cp) and pharmacokinetics of sufentanil injected i.v. (IVS), intradurally (IS) or extradurally (ES) under general anaesthesia in 31 patients undergoing major abdominal surgery. Sufentanil appeared in plasma very rapidly and Cpmax was also attained rapidly after both extradural...

journal_title：British journal of anaesthesia

authors： Ionescu TI,Taverne RH,Houweling PL,Drost RH,Nuijten S,Van Rossum J

更新日期：1991-04-01 00:00:00

abstract：:A disposable patient-controlled analgesia (PCA) device was evaluated in 20 children after major abdominal, urological and orthopaedic surgery. All patients were given a high dependency level of nursing care in general wards. Efficacy (as assessed by hourly pain scores) was comparable to that achieved in a matched cont...

journal_title：British journal of anaesthesia

authors： Irwin M,Gillespie JA,Morton NS

更新日期：1992-04-01 00:00:00

abstract：:Raised intracranial pressure (ICP) and low cerebral blood flow (CBF) are associated with ischaemia and poor outcome after brain injury. Therefore, many management protocols target these parameters. This overview summarizes the technical aspects of ICP and CBF monitoring, and their role in the clinical management of br...

journal_title：British journal of anaesthesia

authors： Steiner LA,Andrews PJ

更新日期：2006-07-01 00:00:00

abstract：:We have compared the efficacy of adding varying concentrations of hyaluronidase to a standard mixture of 2% lidocaine and 1% ropivacaine to provide peribulbar anaesthesia for cataract surgery. We used (i) the time to adequate anaesthesia for surgery and (ii) ocular and eyelid movement scores at 8 min after block as cl...

journal_title：British journal of anaesthesia

authors： Mantovani C,Bryant AE,Nicholson G

更新日期：2001-06-01 00:00:00

abstract：:Plasma concentrations of amethocaine were measured after topical application of amethocaine cream 2 g (5% w/w) to the dorsum of the right hand of 10 adult volunteers. The cream was applied for 240 min and plasma was assayed for amethocaine and its metabolite p-n-butylaminobenzoic acid at 0, 30, 60, 90, 120 and 240 min...

journal_title：British journal of anaesthesia

authors： Mazumdar B,Tomlinson AA,Faulder GC

更新日期：1991-10-01 00:00:00

abstract：:Diaphragm strength can be assessed from twitch gastric (TwPgas), twitch oesophageal (TwPoes), and twitch transdiaphragmatic pressure (TwPdi) in response to phrenic nerve stimulation. This requires the passage of balloon catheters, which may be difficult. Changes in pressure measured at the mouth during phrenic nerve s...

journal_title：British journal of anaesthesia

authors： Mills GH,Ponte J,Hamnegard CH,Kyroussis D,Polkey MI,Moxham J,Green M

更新日期：2001-12-01 00:00:00

abstract：:We have compared, in a double-blind study, the efficacy of flumazenil with that of aminophylline in antagonizing the effects of midazolam in 60 patients (ASA I-II, mean age 66 yr) undergoing transurethral resection of prostate under spinal anaesthesia. All patients received midazolam 0.075 mg kg-1 i.v. and the test dr...

journal_title：British journal of anaesthesia

authors： Sibai AN,Sibai AM,Baraka A

更新日期：1991-05-01 00:00:00

abstract：:Arterial pressure is still one of the most important measures in estimating the required dose of inhaled anaesthetics. It is measured easily and reacts rapidly which makes it suitable as a variable for feedback control of depth of anaesthesia. Fuzzy logic, a novel approach to feedback control, was used to control arte...

journal_title：British journal of anaesthesia

authors： Zbinden AM,Feigenwinter P,Petersen-Felix S,Hacisalihzade S

更新日期：1995-01-01 00:00:00

abstract：:Forty patients who had undergone coronary artery graft surgery and who required vasodilator therapy for postoperative hypertension were given infusions of either alfentanil or morphine together with bolus doses of midazolam for sedation and analgesia while ventilation was controlled artificially. Sodium nitroprusside ...

journal_title：British journal of anaesthesia

authors： McMenemin IM,Church JA,Kenny GN

更新日期：1988-12-01 00:00:00

abstract：:The use of atracurium during major abdominal surgery was assessed in 20 infants with hepatic dysfunction caused by biliary atresia. An initial dose of 0.6 mg kg-1 provided excellent intubating conditions in all patients. Subsequent neuromuscular blockade was monitored with a peripheral nerve stimulator and incremental...

journal_title：British journal of anaesthesia

authors： Simpson DA,Green DW

更新日期：1986-11-01 00:00:00