Abstract：
:Eighteen patients were studied, during operations under subarachnoid or extradural anaesthesia combined with general anaesthesia, to assess the influence of occlusion of inspiration on the duration of inspiration, and the likelihood of a relationship between lung volume and duration of inspiration. Ten patients breathed 2% enflurane and eight breathed 1% halothane, using 67% nitrous oxide in oxygen as carrier gases. The durations of inspiration and of expiration were significantly longer during enflurane administration than during halothane. Occlusion of inspiration reduced significantly the duration of the inspiratory attempt in both groups of patients, but the duration of a complete respiratory cycle was not changed. In patients receiving enflurane, but not in those given halothane, the relative duration of occluded inspiration was positively correlated with the duration of the unoccluded inspiration. There was no evidence with either agent of a reflex relationship between lung volume and inspiratory duration which would have suggested an active Hering-Breuer reflex.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Drummond GBdoi
10.1093/bja/56.3.215subject
Has Abstractpub_date
1984-03-01 00:00:00pages
215-21issue
3eissn
0007-0912issn
1471-6771pii
S0007-0912(17)42370-1journal_volume
56pub_type
杂志文章abstract：:We have compared the effects of sevoflurane and halothane on the discharge frequencies of 19 slowly adapting and four rapidly adapting lung receptors in the rabbit by recording from single vagal fibres. Both agents reduced the discharge frequency of slowly adapting receptors during expiration (P < 0.0005), halothane h...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/80.2.257
更新日期：1998-02-01 00:00:00
abstract：BACKGROUND:Severely obese parturients have increased 'cannot intubate, cannot oxygenate' risk during Caesarean section under general anaesthesia. Front-of-neck access (FONA) at the cricothyroid membrane (CTM) is definitive management; however, attempted FONA can fail. Point-of-care ultrasonography may provide useful in...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2018.02.010
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:The low and moderate doses of dexmedetomidine reduce arterial pressure and heart rate (HR), suggesting attenuation of sympathetic activity and dominance of cardiac-vagal activity. These autonomic responses under dexmedetomidine sedation may attenuate cardiovascular reflex responses to temporal reduction in a...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aep210
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2020.04.009
更新日期：2020-07-01 00:00:00
abstract：:The neuromuscular blocking effects of equipotent doses of the three putative metabolites of vecuronium (3-hydroxy vecuronium, 17-hydroxy vecuronium and 3,17-dihydroxy vecuronium) were compared with those of an equipotent dose of vecuronium. Results obtained with the liver excluded from the circulation and after intrap...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/57.8.789
更新日期：1985-08-01 00:00:00
abstract：:Pyridostigmine 0.143 mg kg-1 (maximum 10 mg) and atropine 0.0143 mg kg-1 (maximum 1 mg) were administered i.v. to six healthy male volunteers. Peripheral venous blood samples were drawn for measurement of serum cholinesterase activity. Maximum inhibition of the enzyme was found 5 min after injection with a decrease to...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/57.2.204
更新日期：1985-02-01 00:00:00
abstract：:The identification of a serum marker to assist in the diagnosis of cerebral injury after cardiac surgery is potentially useful. S100 protein is an early marker of cerebral damage. It is released after cardiac surgery performed under cardiopulmonary bypass (CPB). Its level is correlated with the duration of CPB, deep c...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/85.2.287
更新日期：2000-08-01 00:00:00
abstract：:Forty patients (age range 60-79 yr) undergoing transurethral surgery were allocated randomly to receive 0.5% plain bupivacaine 4 ml at the L2-3 (n = 20) or L4-5 (n = 20) space. The solution was injected over 30 s with the patient in the sitting position. The patient was kept sitting for 2 min, then placed supine and, ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/64.2.170
更新日期：1990-02-01 00:00:00
abstract：:The serum vasopressin (S-AVP) concentration, serum sodium concentration and osmolality, central venous pressure and fluid balance were measured during 10-min periods in 32 patients undergoing transurethral resection of the prostate. Concentration of S-AVP was unaffected by uncomplicated resection; irrigant absorption ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/63.3.330
更新日期：1989-09-01 00:00:00
abstract：:The plasma decay of atracurium besylate was examined in two groups of six patients. Group I received atracurium 0.6 mg kg-1 and group II 0.3 mg kg-1 as a single bolus dose i.v. The plasma concentrations were measured by high performance liquid chromatography. An individual two-compartment pharmacokinetic model was use...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/55.2.113
更新日期：1983-02-01 00:00:00
abstract：:Spinal anaesthesia is the preferred anaesthetic technique for elective Caesarean deliveries. Hypotension is the most common side-effect and has both maternal and neonatal consequences. Different strategies have been attempted to prevent spinal-induced hypotension, including the use of low-dose bupivacaine. We conducte...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,meta分析,评审
doi：10.1093/bja/aer200
更新日期：2011-09-01 00:00:00
abstract：:We have compared the effects of progressive (30% and 60%) in vitro haemodilution with hydroxyethyl starch (HES), gelatin (GEL) and albumin (ALB) with haemodilution using 0.9% saline in 96 patients by thrombelastography. Haemodilution with HES, GEL and ALB significantly (P < 0.05) compromised coagulation time (k), angl...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/78.6.684
更新日期：1997-06-01 00:00:00
abstract：:We have investigated 296 inpatients in a single-blind observer study to determine the incidence, degree and duration of hypoxaemia during anaesthesia. The clinical recognition of hypoxaemia, period of time until recognition and risk factors were studied. Oxygen saturation (Spo2) was monitored continuously with a pulse...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/66.4.437
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND:Tracheal tube tip and cuff positions of different cuffed paediatric tracheal tube brands in the trachea can vary with design. METHODS:Data from three clinical studies with measured tracheal lengths were pooled in a database including 422 children aged from birth to 16 yr. Dimensional data of seven cuffed pa...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2018.05.002
更新日期：2018-08-01 00:00:00
abstract：:Pre- and postjunctional effects of three ethers (enflurane, diethyle ether, and methoxyflurane) and three non-ethers (chloroform, halothane, and trichloroethylene) were studied in the rat phrenic nerve diaphragm preparation using standard microelectrode recording techniques. Depression of postjunctional function inclu...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/47.5.533
更新日期：1975-05-01 00:00:00
abstract：:One hundred and six former or current flexible trainees in anaesthesia responded to a questionnaire evaluating their part-time training (a response rate of 71%). They were compared with a group of 32 flexible trainees in obstetrics and gynaecology. Anaesthetists were more satisfied than obstetricians and gynaecologist...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/81.2.268
更新日期：1998-08-01 00:00:00
abstract：:We report the extradural administration of low-dose morphine in 10 ml of 10% dextrose (2-3 mg) to 98 adult patients with various types of acute and chronic pain. Extradural morphine injections were given either via a Tuohy needle (single or repeat injection) or via an extradural catheter. Pain relief was evaluated by ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/52.3.247
更新日期：1980-03-01 00:00:00
abstract：BACKGROUND:Recent research into memory formation under sedation has generated conflicting results. We investigated explicit and implicit memory in ICU patients during moderate to deep propofol sedation following cardiac surgery. METHODS:Two different methods of memory testing were used; (1). free-association (F-A) wor...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeg274
更新日期：2003-12-01 00:00:00
abstract：:Liver/gas partition coefficients for isoflurane, enflurane, halothane and methoxyflurane increased two-fold in rats killed 16 h after a single injection of 15% ethanol 7 g kg-1. In contrast, blood/gas and brain/gas partition coefficients did not change. Chronic (21 days) ingestion of ethanol increased liver/gas partit...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/58.5.551
更新日期：1986-05-01 00:00:00
abstract：:The minimum local analgesic concentration (MLAC) of bupivacaine in labour is defined as the effective concentration in 50% of subjects (EC50). We have used the technique of double-blinded sequential allocation to quantify the bupivacaine sparing effect of the addition of four different doses of extradural fentanyl in ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/78.5.493
更新日期：1997-05-01 00:00:00
abstract：:A specific technique for detection of pulmonary aspiration during the perioperative period is lacking. In this study, we developed a scintigraphic method for its diagnosis. Technetium 99m sulphur colloid was given orally 2 h before an i.v. infusion of propofol in patients undergoing elective colonoscopy. During the pr...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/87.2.204
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND:The pulmonary artery catheter is invasive and may cause serious complications. A safe method of cardiac output (CO) measurement is needed. We have assessed the accuracy and reliability of a recently marketed self-calibrating arterial pulse contour CO monitoring system (FloTrac/Vigileo) in end-stage liver fai...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aen343
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:The ilioinguinal/iliohypogastric nerve block is a popular regional anaesthetic technique for children undergoing inguinal surgery. The success rate is only 70-80% and complications may occur. A prospective randomized double-blinded study was designed to compare the use of ultrasonography with the conventiona...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aei157
更新日期：2005-08-01 00:00:00
abstract：:A case of an infant receiving orthotopic heart transplantation with over-sized donor heart was reported. Left lower pulmonary venous obstruction after sternotomy closure was detected by transoesophageal echocardiography (TOE) and the decision to delay sternal closure was made and the clinical outcome was very satisfac...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/88.4.590
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:The effect of anaesthetic drugs on long-term oncological outcomes after cancer surgery is an area of current interest. Dexamethasone is widely used in anaesthetic practice; however, its effect on long-term survival and cancer outcomes is not known. This study presents the results of a 5-yr follow-up of patie...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aet577
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Forty-eight ASA I-II patients undergoing total abdominal hysterectomy (TAH) were studied in a double blind, randomized placebo controlled trial of parecoxib for postoperative analgesia. METHODS:All patients were given propofol 2-4 mg kg(-1) i.v., a non-depolarizing muscle relaxant, morphine 10 mg i.v. and p...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aeg139
更新日期：2003-06-01 00:00:00
abstract：Background:Identification of statistically reliable outcomes for comparison among anaesthetists is challenging. Time-weighted intraoperative mean arterial pressure <65 mm Hg (AUC 65 ) is associated with increased odds for myocardial damage. We explored retrospectively whether such hypotension before incision was statis...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aex153
更新日期：2017-07-01 00:00:00
abstract：BACKGROUND:Moderate to deep sedation has been recommended during endoscopic submucosal dissection (ESD). However, it is often accompanied by adverse events such as respiratory depression or aspiration pneumonia. This study investigated the respiratory complications and ESD outcomes of two sedation protocols: moderate s...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeu555
更新日期：2015-07-01 00:00:00
abstract：:Data from two published and one new meta-analysis were reviewed to compare the antiemetic efficacy of three different anaesthetic regimens: (i) propofol anaesthesia compared with another anaesthetic (control); (ii) anaesthesia without nitrous oxide compared with the same anaesthetic with nitrous oxide (control); (iii)...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,meta分析
doi：10.1093/bja/78.3.256
更新日期：1997-03-01 00:00:00
abstract：:Cancer treatment is associated with significant morbidity and mortality. Surgery is a mainstay of treatment for many tumours, and anaesthetists care for cancer patients on a daily basis. Surgery itself induces a stress response and inhibits the immune system, and cancer surgery is associated with the release of tumour...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aev375
更新日期：2015-12-01 00:00:00
