Anaesthesia for surgery in a patient with a transplanted heart.

abstract：:Bupivacaine is used widely as a local anaesthetic but has potential for severe cardiovascular and central nervous system (CNS) toxicity. It has an asymmetric carbon atom giving it a chiral centre, and the commercial preparation is a racemic mixture of its two enantiomers: dextro or R(+)-bupivacaine and levo or S(-)-bu...

journal_title：British journal of anaesthesia

authors： Cox CR,Checketts MR,Mackenzie N,Scott NB,Bannister J

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:The pulmonary artery catheter is invasive and may cause serious complications. A safe method of cardiac output (CO) measurement is needed. We have assessed the accuracy and reliability of a recently marketed self-calibrating arterial pulse contour CO monitoring system (FloTrac/Vigileo) in end-stage liver fai...

journal_title：British journal of anaesthesia

authors： Biancofiore G,Critchley LA,Lee A,Bindi L,Bisà M,Esposito M,Meacci L,Mozzo R,DeSimone P,Urbani L,Filipponi F

更新日期：2009-01-01 00:00:00

abstract：Background:Retrospective clinical studies suggest there is a risk for neurodevelopmental impairment following early childhood exposure to anaesthesia. In the developing animal brain, including those of non-human primates (NHPs), anaesthetics induce apoptotic cell death. We previously reported that a 5 h isoflurane (ISO...

journal_title：British journal of anaesthesia

authors： Noguchi KK,Johnson SA,Dissen GA,Martin LD,Manzella FM,Schenning KJ,Olney JW,Brambrink AM

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Desflurane (DES)-induced preconditioning is mediated by large-conductance calcium-activated potassium channels (BK(Ca)). Whether BK(Ca) are involved in anaesthetic-induced post-conditioning is unknown. We tested the hypothesis that DES-induced post-conditioning is mediated by BK(Ca) upstream of the mitochond...

journal_title：British journal of anaesthesia

authors： Stumpner J,Lange M,Beck A,Smul TM,Lotz CA,Kehl F,Roewer N,Redel A

更新日期：2012-04-01 00:00:00

abstract：:Transoesophageal echocardiography (TOE) is valuable for perioperative monitoring in patients at risk from haemodynamic disturbance. However, its use is not practicable in patients undergoing surgical procedures under regional anaesthesia. We describe two cases showing that transthoracic echocardiography (TTE) has the ...

journal_title：British journal of anaesthesia

authors： Filipovic M,Seeberger MD,Schneider MC,Schmid M,Pargger H,Hunziker P,Skarvan K

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Abnormal serum sodium concentrations are common in patients presenting for surgery. It remains unclear whether these abnormalities are independent risk factors for postoperative mortality. METHODS:This is a secondary analysis of the European Surgical Outcome Study (EuSOS) that provided data describing 46 53...

journal_title：British journal of anaesthesia

authors： Cecconi M,Hochrieser H,Chew M,Grocott M,Hoeft A,Hoste A,Jammer I,Posch M,Metnitz P,Pelosi P,Moreno R,Pearse RM,Vincent JL,Rhodes A,European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society o

更新日期：2016-01-01 00:00:00

abstract：:Fresh gas flows of nitrous oxide, oxygen and halothane at 6, 3, 2 and 1 litre/min were introduced into a circle absorber system. Spontaneous respiration and IPPV were studied and a regression of inspired on delivered oxygen concentration % was calculated. The difference between delivered and inspired oxygen concentrat...

journal_title：British journal of anaesthesia

authors： Raymond JA

更新日期：1976-03-01 00:00:00

abstract：:The trachea of a man who had cut his own throat was successfully intubated using a fibreoptic laryngoscope after attempts at conventional oral intubation had failed. The advantages of the fibreoptic instrument and the method of use in such an injury are discussed. ...

journal_title：British journal of anaesthesia

authors： Davies JR

更新日期：1978-05-01 00:00:00

abstract：:We have undertaken a prospective, randomized study to determine the incidence of postoperative nausea and vomiting during intensive care stay after cardiac surgery, and to study the effect of addition of droperidol to an infusion of morphine used for postoperative analgesia. Data from 398 patients were examined. The u...

journal_title：British journal of anaesthesia

authors： Grebenik CR,Allman C

更新日期：1996-09-01 00:00:00

abstract：:This paper reports three investigations of the suggested relationship between sudden infant death syndrome (SIDS) and malignant hyperpyrexia (MH). In the first study 151 MH-susceptible families completed a questionnaire designed to identify the incidence of SIDS within their own pedigree. In the second study 106 SIDS ...

journal_title：British journal of anaesthesia

authors： Ellis FR,Halsall PJ,Harriman DG

更新日期：1988-01-01 00:00:00

abstract：:A simple method of adapting a pressure-cycled ventilator of the flow generator type to ventilate patients on a circle-absorber anaesthetic system is described. Standard lengths of corrugated black rubber tubing are placed between the ventilator and the circle-absorber is deadspace, replacing the reservoir bag. The per...

journal_title：British journal of anaesthesia

authors： Jeal DE

更新日期：1977-03-01 00:00:00

abstract：:A genetic disorder of the calcium releasing ryanodine receptor has recently been postulated in malignant hyperthermia (MH) and ryanodine-induced contractures differ between subjects who are malignant hyperthermia susceptible (MHS) and non-susceptible (MHN). We tested 39 patients from 26 families for MH, using the proc...

journal_title：British journal of anaesthesia

authors： Lenzen C,Roewer N,Wappler F,Scholz J,Kahl J,Blank M,Rumberger E,Schulte am Esch J

更新日期：1993-08-01 00:00:00

abstract：:Thirty patients took part in a double-blind trial to compare morphine 10 mg i.m. with morphine 5 mg into the extradural space for pain relief following Caesarean section. With the extradural route the mean time to first analgesia was 7.95 h compared with 4.75 h for the i.m. route. The mean number of further doses of d...

journal_title：British journal of anaesthesia

authors： Chambers WA,Mowbray A,Wilson J

更新日期：1983-12-01 00:00:00

abstract：:Nausea and vomiting occur commonly during and after Caesarean delivery (CD) performed under neuraxial anaesthesia. Metoclopramide is a prokinetic agent reported to be safe in parturients. This meta-analysis assesses the efficacy of metoclopramide for prophylaxis against intra- and postoperative nausea and vomiting (IO...

journal_title：British journal of anaesthesia

authors： Mishriky BM,Habib AS

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Tapentadol is an analgesic agent for treatment of acute and chronic pain that activates the µ-opioid receptor combined with inhibition of neuronal norepinephrine reuptake. Both mechanisms are implicated in activation of descending inhibitory pain pathways. In this study, we investigated the influence of tape...

journal_title：British journal of anaesthesia

authors： Niesters M,Proto PL,Aarts L,Sarton EY,Drewes AM,Dahan A

更新日期：2014-07-01 00:00:00

abstract：:Five hundred and seventeen women in labour receiving extradural analgesia, using bupivacaine plain solution, were randomly allocated to one of three groups. Group A received 6-8ml of 0.5% solution, group B 10-14ml of 0.25% solution, and group C 6-8 ml of 0.25% solution. Spontaneous delivery occurred in 31.7% of patien...

journal_title：British journal of anaesthesia

authors： Thorburn J,Moir DD

更新日期：1981-09-01 00:00:00

abstract：:Simple methods are described for computing the variables derived from the Siggaard-Andersen nomogram, where the in vitro buffer line is either established by direct measurement or calculated from measurements of pH, Pco2 and haemoglobin. Calculations are performed using the equation of the pH-log Pco2 buffer line, the...

journal_title：British journal of anaesthesia

authors： Blackburn JP,Preston TD,Strickland DA

更新日期：1975-04-01 00:00:00

abstract：:Logistical and ethical reasons make conducting clinical research in paediatric practice difficult, and therefore safe and efficacious advances are dependent on good preclinical research. For example, notable advances have been made in preclinical studies of pain processing that correlate well with patient data. Other ...

journal_title：British journal of anaesthesia

authors： Sanders RD,Ma D,Brooks P,Maze M

更新日期：2008-11-01 00:00:00

abstract：:We have measured the partial pressure of isoflurane simultaneously in inspired gas (PIiso), end-expired gas (PE'iso), mixed-expired gas (PEiso), arterial (Paiso) and mixed venous blood (Pviso) in six patients (aged 57-79 yr) anaesthetized with nitrous oxide, oxygen and isoflurane before surgery and after PE'iso had be...

journal_title：British journal of anaesthesia

authors： Landon MJ,Matson AM,Royston BD,Hewlett AM,White DC,Nunn JF

更新日期：1993-06-01 00:00:00

abstract：:Interest in the use of psychosocial interventions to help older adults manage pain is growing. In this article, we review this approach. The first section reviews the conceptual background for psychosocial interventions with a special emphasis on the biopsychosocial model of pain. The second section highlights three p...

journal_title：British journal of anaesthesia

authors： Keefe FJ,Porter L,Somers T,Shelby R,Wren AV

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The diagnosis of abdominal compartment syndrome depends upon the demonstration of an elevated intra-abdominal pressure (IAP). Direct measures of IAP are impractical in the critical care unit; intravesical pressure (IVP) and intragastric pressure (IGP) should represent acceptable surrogate measures. IVP is th...

journal_title：British journal of anaesthesia

authors： Turnbull D,Webber S,Hamnegard CH,Mills GH

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Arterial cannulation is a common anaesthetic procedure that can be challenging and time-consuming in small children. By visualizing the position of the radial artery, near-infrared vascular imaging systems (NIRVISs) might be of assistance in arterial cannulation. The present study evaluates the effectiveness...

journal_title：British journal of anaesthesia

authors： Cuper NJ,de Graaff JC,Hartman BJ,Verdaasdonk RM,Kalkman CJ

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Treprostinil sodium improves haemodynamics and symptoms in pulmonary arterial hypertension (PAH) patients, but its subcutaneous (s.c.) administration can produce severe local site pain, and lead to discontinuation of vital treatment. Treprostinil is a prostacyclin analogue which stimulates prostacyclin recep...

journal_title：British journal of anaesthesia

authors： Libri V,Gibbs JS,Pinato DJ,Iddamalgoda T,Khengar RH,Gin-Sing W,Huson L,Anand P

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Growing evidences indicate that inhalational anaesthetics can enhance the growth and malignant potential of tumour cells and may affect tumour recurrence after surgery. Tumour stem cells play a vital role in tumour recurrence. This study investigates the effect of sevoflurane on glioma stem cells (GSCs) in v...

journal_title：British journal of anaesthesia

authors： Shi QY,Zhang SJ,Liu L,Chen QS,Yu LN,Zhang FJ,Yan M

更新日期：2015-05-01 00:00:00

abstract：:The study was performed to determine the ED50 and ED95 of a continuous infusion of the emulsion formulation of propofol during 67% nitrous oxide anaesthesia in 57 patients premedicated with morphine sulphate 0.15 mg kg-1. Anaesthesia was induced with propofol 2 mg kg-1, and maintained before incision with a fixed-rate...

journal_title：British journal of anaesthesia

authors： Spelina KR,Coates DP,Monk CR,Prys-Roberts C,Norley I,Turtle MJ

更新日期：1986-10-01 00:00:00

abstract：:We have examined the effect of isoflurane, halothane and fentanyl on heart rate variability (HRV) using power spectral analysis (PSA). Forty patients were allocated randomly to receive one of four anaesthetic techniques. Anaesthesia was induced with propofol 2 mg kg-1 and all patients breathed a mixture of 66% nitrous...

journal_title：British journal of anaesthesia

authors： Galletly DC,Westenberg AM,Robinson BJ,Corfiatis T

更新日期：1994-02-01 00:00:00

abstract：:The rate of liquid-phase gastric emptying was determined in seven smokers from the rate of paracetamol absorption after abstaining overnight from cigarettes, and again after smoking two cigarettes within 30 min. There were no significant differences between the maximum paracetamol concentration, the time to reach maxi...

journal_title：British journal of anaesthesia

authors： Petring OU,Adelhøj B,Ibsen M,Brynnum J,Poulsen HE

更新日期：1985-11-01 00:00:00

abstract：:Thirty-two patients received lumbar extradural anaesthesia for elective Caesarean section. The results obtained from this series were compared with those from a similar (control) group of parturients who received general anaesthesia. The extradural group (mothers and infants) were metabolically acidaemic relative to c...

journal_title：British journal of anaesthesia

authors： Downing JW,Houlton PC,Barclay A

更新日期：1979-04-01 00:00:00

abstract：:In a prospective randomized multi-centre study, the mortality following internal fixation surgery for fracture of the upper femur was investigated in 538 elderly patients allocated to receive subarachnoid blockade or general (narcotic-relaxant) anaesthesia. The 28-day mortality was 6.6% with subarachnoid, and 5.9% wit...

journal_title：British journal of anaesthesia

authors： Davis FM,Woolner DF,Frampton C,Wilkinson A,Grant A,Harrison RT,Roberts MT,Thadaka R

更新日期：1987-09-01 00:00:00

abstract：:We have examined the effects of sedation with midazolam 0.1 mg kg-1 and reversal with flumazenil 0.5 mg on beat-to-beat heart rate (HR) variability (HRV), systolic arterial pressure (SAP), finger photoplethysmograph amplitude (PLA) and impedence pneumography in eight volunteers. With the onset of sedation there was a ...

journal_title：British journal of anaesthesia

authors： Galletly DC,Williams TB,Robinson BJ

更新日期：1996-04-01 00:00:00