Prediction of inspired oxygen concentration within a circle anaesthetic system.

abstract：:We have examined the effects of the highly selective alpha 2-adrenoceptor agonist, dexmedetomidine, on noradrenaline release and cell firing in isolated, superfused slices of rat locus coeruleus. Dexmedetomidine decreased both noradrenaline release and cell firing rate in a concentration-dependent fashion, with an EC5...

journal_title：British journal of anaesthesia

authors： Jorm CM,Stamford JA

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Tapentadol is an analgesic agent for treatment of acute and chronic pain that activates the µ-opioid receptor combined with inhibition of neuronal norepinephrine reuptake. Both mechanisms are implicated in activation of descending inhibitory pain pathways. In this study, we investigated the influence of tape...

journal_title：British journal of anaesthesia

authors： Niesters M,Proto PL,Aarts L,Sarton EY,Drewes AM,Dahan A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:In critically ill children, monitoring of cardiac output (CO) is essential to guide haemodynamic management and facilitate cardiovascular therapy. The ultrasound dilution technique (UDT), a novel minimally invasive indicator method, was recently introduced to determine CO. We validated UDT against the 'gold ...

journal_title：British journal of anaesthesia

authors： Boehne M,Baustert M,Paetzel V,Köditz H,Schoof S,Happel CM,Bertram H

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the prevalence of postoperative nausea and vomiting (PONV) after fast-track cardiac anaesthesia, risk factors for PONV and its influence on the length of stay in the intensive care unit (ICU). METHODS:A prospective study was performed in the cardiothoracic ICU (CTICU) ...

journal_title：British journal of anaesthesia

authors： Kogan A,Eidelman LA,Raanani E,Orlov B,Shenkin O,Vidne BA

更新日期：2003-08-01 00:00:00

abstract：:In a randomized, double-blind study, we have examined the stereoselective disposition and pharmacodynamic characteristics of ketamine in surgical patients after i.v. administration of S(+)-ketamine 1 mg/kg body weight (25 patients) or racemic ketamine 2 mg/kg body weight (25 patients). S(+)-Ketamine was not inverted t...

journal_title：British journal of anaesthesia

authors： Geisslinger G,Hering W,Thomann P,Knoll R,Kamp HD,Brune K

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Low bispectral index values frequently reflect EEG suppression and have been associated with postoperative mortality. This study investigated whether intraoperative EEG suppression was an independent predictor of 90 day postoperative mortality and explored risk factors for EEG suppression. METHODS:This obse...

journal_title：British journal of anaesthesia

authors： Willingham M,Ben Abdallah A,Gradwohl S,Helsten D,Lin N,Villafranca A,Jacobsohn E,Avidan M,Kaiser H

更新日期：2014-12-01 00:00:00

abstract：:The plasma decay of atracurium besylate was examined in two groups of six patients. Group I received atracurium 0.6 mg kg-1 and group II 0.3 mg kg-1 as a single bolus dose i.v. The plasma concentrations were measured by high performance liquid chromatography. An individual two-compartment pharmacokinetic model was use...

journal_title：British journal of anaesthesia

authors： Ward S,Neill EA,Weatherley BC,Corall IM

更新日期：1983-02-01 00:00:00

abstract：:Eighty-one consenting women undergoing elective Caesarean section under spinal anaesthesia were randomly divided into two groups. In Group O patients, ondansetron 4 mg was given intravenously at the end of the surgery and 8 mg added to the morphine solution in the PCA syringe. Patients in Group P received only morphin...

journal_title：British journal of anaesthesia

authors： Cherian VT,Smith I

更新日期：2001-09-01 00:00:00

abstract：:Cryoprecipitate, originally developed as a therapy for patients with antihaemophilic factor deficiency, or haemophilia A, has been in use for almost 50 yr. However, cryoprecipitate is no longer administered according to its original purpose, and is now most commonly used to replenish fibrinogen levels in patients with...

journal_title：British journal of anaesthesia

authors： Nascimento B,Goodnough LT,Levy JH

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Chronic treatment with renin-angiotensin system (RAS) antagonists frequently causes deleterious hypotension during anaesthesia. We compared the effects of angiotensin II receptor antagonists (ARA) and angiotensin-converting enzyme inhibitors (ACEI) on neurohormonal levels and haemodynamics during cardiopulmo...

journal_title：British journal of anaesthesia

authors： Oh YJ,Lee JH,Nam SB,Shim JK,Song JH,Kwak YL

更新日期：2006-12-01 00:00:00

abstract：:In this study, we have compared two different doses of clonidine (bolus of 25 micrograms and infusion of 19 micrograms h-1; bolus of 50 micrograms and infusion of 37 micrograms h-1, both added to 0.03% bupivacaine) with a control group of 0.03% bupivacaine alone. The study was performed in a randomized, double-blind m...

journal_title：British journal of anaesthesia

authors： Tremlett MR,Kelly PJ,Parkins J,Hughes D,Redfern N

更新日期：1999-08-01 00:00:00

abstract：:General anaesthesia for emergency surgery in a pressurized habitat is likely to involve the use of i.v. agents. The anaesthetic property of such agents is known to be antagonized by pressure, but the effect on their duration of action is not easily predicted. The recovery of mice from a single i.v. dose of Althesin, k...

journal_title：British journal of anaesthesia

authors： Shearer AJ,Ross JA,Manson HJ

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Supraglottic airways (SGAs) have an established role in airway management of difficult airways in both adults and children. However, there are limited data regarding the use of SGAs for primary airway management in children. The aim of this study is to assess the success rates and adverse events related to t...

journal_title：British journal of anaesthesia

authors： Jagannathan N,Sequera-Ramos L,Sohn L,Wallis B,Shertzer A,Schaldenbrand K

更新日期：2014-04-01 00:00:00

abstract：:Three anaesthetic techniques based on isoflurane were compared in outpatients undergoing laparoscopy. Sixty healthy patients were randomly allocated to receive isoflurane via mask (spontaneous respiration), via tracheal tube (spontaneous respiration) or via tracheal tube with controlled ventilation. Moderate hypercarb...

journal_title：British journal of anaesthesia

authors： Kenefick JP,Leader A,Maltby JR,Taylor PJ

更新日期：1987-02-01 00:00:00

abstract：:The effects of diazepam, which acts at GABAA receptors to enhance the effects of GABA, and ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, on local rates of cerebral glucose utilization (ICMRglc) were examined in unrestrained rats. Four groups were studied: vehicle-injected controls; and ketamine...

journal_title：British journal of anaesthesia

authors： Eintrei C,Sokoloff L,Smith CB

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Severely obese parturients have increased 'cannot intubate, cannot oxygenate' risk during Caesarean section under general anaesthesia. Front-of-neck access (FONA) at the cricothyroid membrane (CTM) is definitive management; however, attempted FONA can fail. Point-of-care ultrasonography may provide useful in...

journal_title：British journal of anaesthesia

authors： Gadd K,Wills K,Harle R,Terblanche N

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Overt stroke after non-cardiac surgery has a substantial impact on the duration and quality of life. Covert stroke in the non-surgical setting is much more common than overt stroke and is associated with an increased risk of cognitive decline and dementia. Little is known about covert stroke after non-cardia...

journal_title：British journal of anaesthesia

authors： Mrkobrada M,Hill MD,Chan MT,Sigamani A,Cowan D,Kurz A,Sessler DI,Jacka M,Graham M,Dasgupta M,Dunlop V,Emery DJ,Gulka I,Guyatt G,Heels-Ansdell D,Murkin J,Pettit S,Sahlas DJ,Sharma M,Sharma M,Srinathan S,St John P

更新日期：2016-08-01 00:00:00

abstract：:The effect of alfentanil on sympathetic reflexes evoked by supramaximal electrical stimulation of the radial nerve has been observed in five dogs anaesthetized with alpha-chloralose, paralysed with suxamethonium and artificially ventilated. In five dogs during the infusion of alfentanil at a rate of 20 micrograms kg-1...

journal_title：British journal of anaesthesia

authors： Swenzen GO,Chakrabarti MK,Sapsed-Byrne S,Whitwam JG

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Left ventricular stroke volume variation (SVV) has been shown to be a predictor of fluid responsiveness in various subsets of patients. However, the accuracy and reliability of SVV are unproven in patients ventilated with low tidal volumes. METHODS:Fourteen patients were studied immediately after coronary a...

journal_title：British journal of anaesthesia

authors： Rex S,Brose S,Metzelder S,Hüneke R,Schälte G,Autschbach R,Rossaint R,Buhre W

更新日期：2004-12-01 00:00:00

abstract：:Intravenous dose-response relationships for dimethyl tubocurarine showed that vagal blockade only became appreciable (50-83%) at doses 8-16 times those sufficient for full neuromuscular paralysis in anaesthetized cats (0.0625 mg/kg) and rhesus monkeys (0.125 mg/kg); heart rate was unchanged. Sympathetic function was u...

journal_title：British journal of anaesthesia

authors： Hughes R,Chapple DJ

更新日期：1976-09-01 00:00:00

abstract：:We evaluated prospectively the use of Gram staining of protected pulmonary specimens to allow the early diagnosis of ventilator-associated pneumonia (VAP), compared with the use of 60 bronchoscopic protected specimen brushes (PSB) and 126 blinded plugged telescopic catheters (PTC) obtained from 134 patients. Gram stai...

journal_title：British journal of anaesthesia

authors： Mimoz O,Karim A,Mazoit JX,Edouard A,Leprince S,Nordmann P

更新日期：2000-11-01 00:00:00

abstract：:A blind comparison was made of butorphanol 2 mg with morphine 10 mg i.m. as the sole premedication in four groups, each of 10 women, undergoing total abdominal hysterectomy. On both subjective and objective grounds, butorphanol was as effective as morphine with the advantage of fewer unwanted side-effects, although on...

journal_title：British journal of anaesthesia

authors： Laffey DA,Kay NH

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Multiple studies have shown that cerebral tissue oxygen saturation (Sct(O(2))) is decreased after phenylephrine treatment. We hypothesized that the negative impact of phenylephrine administration on Sct(O(2)) is affected by arterial blood carbon dioxide partial pressure (Pa(CO(2))) because CO(2) is a powerfu...

journal_title：British journal of anaesthesia

authors： Meng L,Gelb AW,Alexander BS,Cerussi AE,Tromberg BJ,Yu Z,Mantulin WW

更新日期：2012-05-01 00:00:00

abstract：:To understand the cellular and molecular basis of the anaesthetic state, it is important to remember that, in the intact CNS, synapses operate within elaborate nerve networks. From the data presented above, it is evident that block of impulse conduction in presynaptic fibres does not explain the effects of most anesth...

journal_title：British journal of anaesthesia

authors： Pocock G,Richards CD

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Aortocaval compression (ACC) can result in haemodynamic disturbances and uteroplacental hypoperfusion in parturients. Its detection is difficult because in most patients, sympathetic compensation results in no signs or symptoms. However, profound hypotension may develop after sympathectomy during regional an...

journal_title：British journal of anaesthesia

authors： Lee SW,Khaw KS,Ngan Kee WD,Leung TY,Critchley LA

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Midlatency auditory evoked potentials (MLAEP) are a promising tool for monitoring suppression of sensory processing during anaesthesia and might help to avoid awareness. MLAEP in children are different to those in adults and the exact changes during general anaesthesia are unknown. METHODS:In 49 children of...

journal_title：British journal of anaesthesia

authors： Daunderer M,Feuerecker MS,Scheller B,Pape NB,Schwender D,Kuhnle GE

更新日期：2007-12-01 00:00:00

abstract：:Twelve hydrocephalic patients undergoing hydrodynamic studies and shunt procedures during general anaesthesia were subjected to short term observations of the cerebrovascular effects of isoflurane. Intraventricular pressure (IVP), arterial pressure (AP); cerebral perfusion pressure (CPP = AP-IVP), end-tidal PCO2, Cere...

journal_title：British journal of anaesthesia

authors： Lundar T,Lindegaard KF,Refsum L,Rian R,Nornes H

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Propofol can scavenge free radicals because it has a chemical structure similar to antioxidants. METHODS:We examined if free radical scavenging occurs with propofol during CABG operations. We studied 24 patients undergoing CABG surgery for triple vessel disease, randomized into two groups. After induction o...

journal_title：British journal of anaesthesia

authors： Sayin MM,Ozatamer O,Taşöz R,Kilinç K,Unal N

更新日期：2002-08-01 00:00:00

abstract：:A computer-controlled infusion of propofol designed to achieve a target blood concentration of propofol 3 microgram ml-1 was used to investigate the possibility of an interaction between propofol and fentanyl in 32 patients undergoing body surface surgery. In 16 patients who were not receiving a neuromuscular blocker ...

journal_title：British journal of anaesthesia

authors： Dixon J,Roberts FL,Tackley RM,Lewis GT,Connell H,Prys-Roberts C

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Sepsis-induced organ failure is the major cause of death in critical care units, and is characterized by a massive dysregulated inflammatory response and oxidative stress. We investigated the effects of treatment with antioxidants that protect mitochondria (MitoQ, MitoE, or melatonin) in a rat model of lipop...

journal_title：British journal of anaesthesia

authors： Lowes DA,Webster NR,Murphy MP,Galley HF

更新日期：2013-03-01 00:00:00