Role of the massive transfusion protocol in the management of haemorrhagic shock.

abstract：:Development targets in anaesthetic pharmacology have evolved from minimizing harm caused by unwanted effects through an era in which rapid onset and offset of drug effect were prioritised. Today's anaesthetists have access to a library of effective drugs whose characteristics offer controllable hypnosis, analgesia and...

journal_title：British journal of anaesthesia

authors： Sneyd JR

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Chronic pain is no longer an effective warning system, but a syndrome with co-morbidities and many causes, needing a careful evaluation. Questions remain about the pain behaviour of chronic pain patients compared with patients with acute pain, or healthy subjects that we investigated. METHODS:We compared th...

journal_title：British journal of anaesthesia

authors： Tuna T,Van Obbergh L,Van Cutsem N,Engelman E

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Using a carrageenan inflammation rat model, we evaluated two experimental approaches to prolong sciatic nerve block on contralateral hyperalgesia. Method. We performed ipsilateral sciatic nerve block on the inflamed hind paw with bupivacaine-loaded microspheres suspended in dexamethasone (bupivacaine 12.5 mg...

journal_title：British journal of anaesthesia

authors： Estebe JP,Gentili ME,Le Corre P,Leduc C,Moulinoux JP,Ecoffey C

更新日期：2004-11-01 00:00:00

abstract：:The serum vasopressin (S-AVP) concentration, serum sodium concentration and osmolality, central venous pressure and fluid balance were measured during 10-min periods in 32 patients undergoing transurethral resection of the prostate. Concentration of S-AVP was unaffected by uncomplicated resection; irrigant absorption ...

journal_title：British journal of anaesthesia

authors： Hahn RG,Rundgren M

更新日期：1989-09-01 00:00:00

abstract：:Midazolam 0.3 mg kg-1 was given as a single dose to three groups of children undergoing cardiac surgery to determine its pharmacokinetic profile in this situation. The first group, undergoing closed heart surgery, received the midazolam during the operation. The other groups underwent cardiopulmonary bypass (CPB) with...

journal_title：British journal of anaesthesia

authors： Mathews HM,Carson IW,Lyons SM,Orr IA,Collier PS,Howard PJ,Dundee JW

更新日期：1988-09-01 00:00:00

abstract：:We describe a case of a 9-yr-old child with sickle cell disease complicated by abdominal vaso-occlusive crisis and priapism. Both complications were successfully treated with a combination of epidural local anesthetics and morphine. ...

journal_title：British journal of anaesthesia

authors： Labat F,Dubousset AM,Baujard C,Wasier AP,Benhamou D,Cucchiaro G

更新日期：2001-12-01 00:00:00

abstract：:A variant of a rebreathing/indicator-dilution technique was used to measure lung volume. Two or three indicators, which should have essentially the same pulmonary volume of distribution, were used. Gas compositions were measured by respiratory mass spectrometry and an extrapolation was used to allow for oxygen consump...

journal_title：British journal of anaesthesia

authors： Black AM,Hahn CE,Maynard P,Scott IL

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Propofol can scavenge free radicals because it has a chemical structure similar to antioxidants. METHODS:We examined if free radical scavenging occurs with propofol during CABG operations. We studied 24 patients undergoing CABG surgery for triple vessel disease, randomized into two groups. After induction o...

journal_title：British journal of anaesthesia

authors： Sayin MM,Ozatamer O,Taşöz R,Kilinç K,Unal N

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Guidelines recommend discontinuation of clopidogrel for 7 days before a neuraxial injection, while other directives suggest that 5 days might be adequate. We examined the time course of antiplatelet activity after clopidogrel discontinuation in patients undergoing epidural injections. METHODS:Thirteen patie...

journal_title：British journal of anaesthesia

authors： Benzon HT,McCarthy RJ,Benzon HA,Kendall MC,Robak S,Lindholm PF,Kallas PG,Katz JA

更新日期：2011-12-01 00:00:00

abstract：:Dose-response relationships for the antagonism of intermediate-acting neuromuscular blocking agents have not been evaluated previously in children. We have examined the dose-response relationships for neostigmine antagonism of 90% rocuronium-induced neuromuscular block in children and adults, during nitrous oxide-1 MA...

journal_title：British journal of anaesthesia

authors： Abdulatif M,Mowafi H,al-Ghamdi A,el-Sanabary M

更新日期：1996-12-01 00:00:00

abstract：:We studied 52 adults undergoing elective craniotomy, allocated randomly to one of three opioid treatments: alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 until dural closure (group Alf.); alfentanil 50 micrograms kg-1 followed by 0.833 microgram kg-1 min-1 for 2 h, then remifentanil 0.25 microgra...

journal_title：British journal of anaesthesia

authors： Sneyd JR,Whaley A,Dimpel HL,Andrews CJ

更新日期：1998-09-01 00:00:00

abstract：:Human error poses significant risk for hospitalized patients causing an estimated 100,000 to 400,000 deaths in the USA annually. Medication errors contribute, with error occurring in 5.3% of medication administrations during surgery. In this study 70.3% of medication errors were deemed preventable. Given the paucity o...

journal_title：British journal of anaesthesia

authors： Wahr JA,Abernathy JH 3rd,Lazarra EH,Keebler JR,Wall MH,Lynch I,Wolfe R,Cooper RL

更新日期：2017-01-01 00:00:00

abstract：:Alveolar type II (ATII) cells perform many important functions within the lung, including surfactant metabolism. We have investigated the effects of isoflurane and different i.v. anaesthetics on cell metabolism in primary cultures of rat ATII cells. Biosynthesis of phosphatidylcholine, the main phospholipid component ...

journal_title：British journal of anaesthesia

authors： Molliex S,Crestani B,Dureuil B,Rolland C,Aubier M,Desmonts JM

更新日期：1999-05-01 00:00:00

abstract：:We describe the anaesthetic management of a patient who underwent transthoracic endoscopic vagotomy. One-lung ventilation was necessary to provide adequate surgical access. Potential intraoperative problems involved arterial oxygen saturation during one-lung ventilation, unequal intrathoracic pressures causing mediast...

journal_title：British journal of anaesthesia

authors： Chui PT,Gin T,Chung SC

更新日期：1992-03-01 00:00:00

abstract：:We have studied haemodynamic responses to 0, 0.25, 0.5, 0.75 and 1 MAC isoflurane administration in 10 patients during a zero-order propofol infusion and normocapnia. Isoflurane reduced mean arterial pressure (MAP), systemic vascular resistance and left ventricular stroke work in a dose-dependent manner (29%, 38% and ...

journal_title：British journal of anaesthesia

authors： Verborgh C,Verbessem D,Camu F

更新日期：1992-07-01 00:00:00

abstract：:It is generally accepted that halothane reduces airway and tissue resistance in lungs with preexisting airway tone. However, under conditions of resting airway tone, pulmonary resistance remains unaltered. In this study, we have determined the effects of halothane on respiratory system, pulmonary and chest wall resist...

journal_title：British journal of anaesthesia

authors： Reta GS,Riva JA,Piriz H,Medeiros AS,Rocco PR,Zin WA

更新日期：2000-03-01 00:00:00

abstract：:The relative sensitivity of sympathetic preganglionic and postganglionic axons, B and C fibres, respectively, to two structurally dissimilar local anaesthetics was examined. The concentration of amethocaine (ester-linked tertiary amine) or prilocaine (amide-linked secondary amine) required to reduce the B fibre compou...

journal_title：British journal of anaesthesia

authors： Scurlock JE,Heavner JE,de Jong RH

更新日期：1975-11-01 00:00:00

abstract：:The effect of the intrathecal administration of diamorphine on the hyperglycaemic, adrenocortical and cardiovascular responses to major colonic surgery were investigated, and the results compared with those obtained in a similar group of patients receiving low doses of fentanyl. In the group receiving intrathecal diam...

journal_title：British journal of anaesthesia

authors： Child CS,Kaufman L

更新日期：1985-04-01 00:00:00

abstract：:An investigation was carried out into the relationship between the inflation pressures of normally compliant lungs and the airways pressure necessary to produce the insufflation of gas to the stomach. This relationship was examined during manual ventilation with a mask, using a rapid sequence induction technique. In t...

journal_title：British journal of anaesthesia

authors： Lawes EG,Campbell I,Mercer D

更新日期：1987-03-01 00:00:00

abstract：:We describe the management of three patients undergoing awake carotid surgery who developed signs of cerebral ischaemia after carotid cross-clamping. Drug treatment to increase arterial blood pressure above baseline reversed the neurological deficit and an internal carotid artery shunt was not needed. Shunt insertion ...

journal_title：British journal of anaesthesia

authors： Stoneham MD,Warner O

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Cardiac output (CO) monitoring is helpful in the assessment of critically ill pregnant women, but invasive monitors are often unsuitable for use. We aimed to measure agreement between the non-invasive ultrasound cardiac output monitor (USCOM) and three-dimensional transthoracic echocardiography (3D-TTE) in p...

journal_title：British journal of anaesthesia

authors： McNamara H,Barclay P,Sharma V

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:To study adequate antinociception during general anaesthesia, tetanic stimulus of 5-10 s duration has been used previously as a standardized nociceptive stimulus. However, such stimuli have been found to correlate poorly with intraoperative nociception. We hypothesized that an electrical tetanic stimulus of ...

journal_title：British journal of anaesthesia

authors： Rantanen M,Yppärilä-Wolters H,van Gils M,Yli-Hankala A,Huiku M,Kymäläinen M,Korhonen I

更新日期：2007-10-01 00:00:00

abstract：:The effect of ketamine analgesia on gastric emptying was assessed in five healthy volunteers. Gastric emptying, estimated indirectly by the absorption of orally administered paracetamol, was not significantly delayed following administration of i.m. ketamine when compared with placebo. ...

journal_title：British journal of anaesthesia

authors： Grant IS,Nimmo WS,Clements JA

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Arousal after sevoflurane anaesthesia has been detectable by monitoring changes in skin conductance (SC) with similar accuracy as monitoring Bispectral Index (BIS). As SC monitoring detects changes in sympathetic tone, the measurements might be confounded by the sympatholytic properties of propofol, a compon...

journal_title：British journal of anaesthesia

authors： Ledowski T,Bromilow J,Paech MJ,Storm H,Hacking R,Schug SA

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:The relationship between end-tidal sevoflurane concentration, bispectral index (BIS) and the EEG bispectrum in children appears to be age dependent. The aim of this study was to quantify the BIS values at 1 MAC (minimum alveolar concentration) for desflurane and halothane, and explore the relationship with a...

journal_title：British journal of anaesthesia

authors： Tirel O,Wodey E,Harris R,Bansard JY,Ecoffey C,Senhadji L

更新日期：2006-04-01 00:00:00

abstract：:The haemodynamic responses to isovolumic anaemia (dextran-for-blood exchange) were studied in seven dogs pretreated with propranolol 20 mg/kg body weight for 3 weeks. Adrenergic beta-receptor blockade did not prevent significant increases in heart rate (up to 19%). Cardiac output increased by about 20% while systemic ...

journal_title：British journal of anaesthesia

authors： Clarke TN,Foëx P,Roberts JG,Saner CA,Bennett MJ

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Paradoxical excitement response during sedation consists of loss of affective control and abnormal movements. Chronic alcohol abuse has been proposed as a predisposing factor despite lack of supporting evidence. Because alcohol and propofol have a common site of action, we postulated that paradoxical excitem...

journal_title：British journal of anaesthesia

authors： Jeong S,Lee HG,Kim WM,Jeong CW,Lee SH,Yoon MH,Choi JI

更新日期：2011-12-01 00:00:00

abstract：:This editorial looks at some of the various anesthesias used during pregnancy termination. Trichloroethylene, often a popular substitute for halothane, has been subjected to little evaluation. Only clinical study however, can actually establish the significance of myometrial depressant properties in the pregnant pat...

journal_title：British journal of anaesthesia

authors： Grant IS

更新日期：1980-08-01 00:00:00

abstract：:In order to evaluate the use of the post-tetanic count (PTC) method during repetitive administration of vecuronium, we studied 20 patients allocated randomly to one of two groups: 10 patients received droperidol-fentanyl anaesthesia (control group); 10 other patients were given droperidol-fentanyl anaesthesia modified...

journal_title：British journal of anaesthesia

authors： Eriksson LI,Lennmarken C,Staun P,Viby-Mogensen J

更新日期：1990-10-01 00:00:00

abstract：:We determined in 51 healthy patients undergoing body surface surgery the dose requirements for propofol, as part of a total i.v. anaesthesia technique with an alfentanil infusion. After premedication with temazepam, patients received alfentanil 50 micrograms kg-1 followed by an infusion of 50 micrograms kg-1 h-1. Pati...

journal_title：British journal of anaesthesia

authors： Richards MJ,Skues MA,Jarvis AP,Prys-Roberts C

更新日期：1990-08-01 00:00:00