Relationship between resonance and gas exchange during high frequency jet ventilation.

Abstract:

:We have studied the relationship between gas exchange and mechanical frequency response during high frequency jet ventilation (HFJV) at 0.5-5.0 Hz in anaesthetized pigs. The mechanical gain curve showed a minimal "anti-resonant" response at 0.8 Hz (f1) and a maximal "resonant" response at 5.0 Hz (f2). This finding may be explained by modelling the thorax and abdomen as a system of coupled masses and compliances which undergo two different modes of forced oscillation in the frequency range studied. Gas exchange was optimal in the frequency range between the minimal and maximal responses. The tidal volumes produced were greater than anatomical deadspace, suggesting that gas transport was mainly convective in this range.

journal_name

Br J Anaesth

authors

Lin ES,Jones MJ,Mottram SD,Smith BE,Smith G

doi

10.1093/bja/64.4.453

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

453-9

issue

4

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)53434-0

journal_volume

64

pub_type

杂志文章
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