Abstract：
:One hundred and forty male rats received a cryoinjury to a segment of the exposed sciatic nerve. A variety of temperatures and freeze patterns was used and the recovery of function was monitored. Where obvious nerve freezing occurred, the cryoinjury caused complete loss of function in the limb. The return of motor activity was first noted at 25 days (mean) but complete return of motor activity and of pain sensation was noted after 38 days (mean). The findings were consistent with an axonal growth rate of 1 mm per day. The time taken for regeneration was independent of both the duration of freezing and the application of a repeat freeze cycle. The temperature attained by the nerve was, however, important. Where it remained greater than -20 degrees C the result were unpredictable, but below this temperature the interruption was prolonged and uninfluenced by greater reductions in temperature.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Evans PJ,Lloyd JW,Green CJdoi
10.1093/bja/53.11.1121subject
Has Abstractpub_date
1981-11-01 00:00:00pages
1121-7issue
11eissn
0007-0912issn
1471-6771pii
S0007-0912(17)42871-6journal_volume
53pub_type
杂志文章abstract：BACKGROUND:This study focuses on a recently developed robotic nerve block system and its impact on learning regional anaesthesia skills. We compared success rates, learning curves, performance times, and inter-subject performance variability of robot-assisted vs manual ultrasound (US)-guided nerve block needle guidance...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aet440
更新日期：2014-06-01 00:00:00
abstract：:Although well established in clinical practice, both propofol and midazolam have limitations. New hypnotics with different and potentially superior pharmacokinetics and pharmacodynamics are under development. These include the benzodiazepine receptor agonists CNS7056 and JM-1232 (-), the etomidate-based methoxycarbony...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aeq190
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND:The immobilizing effects of volatile anaesthetics are primarily mediated at the spinal level. A suppression of recurrent spinal responses (F-waves), which reflect spinal excitability, has been shown for propofol. We have assessed the concentration-dependent F-wave suppression by propofol and related it to th...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aei283
更新日期：2006-01-01 00:00:00
abstract：:The problems of selection of tracheal tubes, and the need for a rationale, are outlined. Tracheal tubes of 7.5 mm and 8.5 mm i.d. are recommended for female and male patients, respectively. Tracheal size was determined using high pressure-low volume cuffs as measuring devices. The average diameter of the cuff at seal ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/58.1.111
更新日期：1986-01-01 00:00:00
abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief, Professor Hugh Hemmings, based on the recommendations of Justus-Liebig-University Giessen f...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,撤回出版物
doi：10.1016/j.bja.2020.07.036
更新日期：2020-09-01 00:00:00
abstract：:Experiments were performed on 14 anaesthetized, artifically ventilated dogs, in which efferent activity in the phrenic nerve was recorded and blood-gas tensions, arterial pH and core temperature were controlled. Doses of midazolam between 0.2 mg kg-1 and 2 mg kg-1 abolished phrenic nerve activity for periods between 3...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/56.10.1161
更新日期：1984-10-01 00:00:00
abstract：BACKGROUND:Desflurane at more than 1 minimum alveolar concentration (MAC) has been shown to prolong the QT interval, but it is unclear whether this is the case at lower concentrations. The aim of this study was to determine whether desflurane concentrations of <1 MAC affect tracheal intubation-induced prolongation of t...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aep355
更新日期：2010-02-01 00:00:00
abstract：:Acute perioperative changes in arterial pressure occur frequently, particularly in patients with cardiovascular disease or those receiving vasoactive medications, or in relation to certain cardiovascular surgical procedures. Both hypo- and hypertension are common in patients undergoing carotid surgery because of uniqu...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aep012
更新日期：2009-04-01 00:00:00
abstract：Background:In addition to general anaesthetic effects, sevoflurane can also induce hyperactive behaviours during induction and recovery, which may contribute to neurotoxicity; however, the mechanism of such effects is unclear. Volatile anaesthetics including isoflurane have been found to activate the kainate (GluK2) re...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aex043
更新日期：2017-11-01 00:00:00
abstract：:This report describes the anaesthetic management of a ventricular arrhythmia-prone patient with a prolonged Q-T interval for closed reduction and wiring of a mandibular fracture. The patient was premedicated with propranolol and anaesthetized with isoflurane (inhalation). Documentation of heart rate v. Q-T interval re...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/55.4.361
更新日期：1983-04-01 00:00:00
abstract：:The interaction of three new non-depolarizing neuromuscular blocking agents--atracurium, vecuronium and Duador--on human red cell acetylcholinesterase (AChE; EC 3.1.1.7) and human plasma butyrylcholinesterase (BuChE; EC 3.1.1.8) was investigated. The binding of these neuromuscular blockers to human plasma proteins (pr...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：:The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/68.4.344
更新日期：1992-04-01 00:00:00
abstract：:The concentrations of volatile hydrocarbons were studied in breath samples from patients before and after anaesthesia. In patients to whom halothane was administered, there was a significant increase in the concentration of isobutene (from 0.43 +/- 0.09 to 4.66 +/- 2.22 nmol litre-1). There was no change in the concen...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/52.10.989
更新日期：1980-10-01 00:00:00
abstract：:We prospectively studied spontaneous recovery from cisatracurium-induced neuromuscular block in 18 patients scheduled for cardiac surgery, and its suitability for fast-track cardiac surgery. Neuromuscular block was induced by an i.v. bolus (range 0.15-0.3 mg kg(-1)) and maintained by a continuous infusion (range 1.1-3...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/86.1.130
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Medication-related adverse events (MRE) in anaesthesia care are frequent and require a deeper understanding if we are to prevent medication harm. METHODS:We searched for reported MRE from the Spanish Anaesthesia Incident Reporting System (SENSAR) database over a 10-yr period. SENSAR is a cross-national, mul...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bja.2019.10.013
更新日期：2020-02-01 00:00:00
abstract：:Cholinesterase phenotyping studies have been carried out in two laboratories on blood specimens from 28 patients shown to be susceptible to malignant hyperpyrexia. In contrast to previously published reports, no evidence could be found for an increase in the frequency of the E1u E1f genotype above that known to occur ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/53.3.245
更新日期：1981-03-01 00:00:00
abstract：BACKGROUND:The pathophysiology of the serotoninergic system in malignant hyperthermia (MH) is not completely understood. The serotonin-2 (5HT(2A)) receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI) induces typical MH symptoms, including skeletal muscle rigidity, an increase in body tempe...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeg172
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:Descriptions of the pharmacokinetics and metabolism of morphine and its metabolites in young children are scant. Previous studies have not differentiated the effects of size from those related to age during infancy. METHODS:Postoperative children 0-3 yr old were given an intravenous loading dose of morphine...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aeh042
更新日期：2004-02-01 00:00:00
abstract：:We describe the management of three patients undergoing awake carotid surgery who developed signs of cerebral ischaemia after carotid cross-clamping. Drug treatment to increase arterial blood pressure above baseline reversed the neurological deficit and an internal carotid artery shunt was not needed. Shunt insertion ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/87.4.641
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND:The safety of performing spinal anaesthesia for both patients and anaesthetists alike in the presence of active infection with the novel coronavirus disease 2019 (COVID-19) is unclear. Here, we report the clinical characteristics and outcomes for both patients with COVID-19 and the anaesthetists who provided...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2020.03.007
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Even mild perioperative hypothermia is associated with several severe adverse effects. Resistive heating has possible advantages compared with other active warming systems because it can heat several fields independently. To assess this new warming system, we measured core temperature in patients during surg...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aeg106
更新日期：2003-05-01 00:00:00
abstract：:We studied the effects of minor surgery and endotracheal intubation on postoperative breathing patterns. We measured breathing patterns and laryngeal resistance during the periods immediately before intubation (preoperative) and immediately after extubation following minor surgery (postoperative) in eight patients ana...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/87.5.706
更新日期：2001-11-01 00:00:00
abstract：:We calculated oxygen consumption by the reverse Fick principle (cVO2) using cardiac output measured with a new technique of continuous thermal dilution and compared these values with measurements made at the same time using a gas exchange method (mVO2). We studied nine patients in a stable condition after cardiac surg...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/75.6.719
更新日期：1995-12-01 00:00:00
abstract：:An analysis of neuromuscular transmission has been made in phrenic nerve/diaphragm preparations from male rats aged 30 days or 110 days. The amplitude of miniature end-plate potentials was found to decrease with age, being 0.969 +/- SEM 0.058 mV at 30 days and 0.510 +/- SEM 0.031 mV at 110 days. Over the same period, ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/49.3.217
更新日期：1977-03-01 00:00:00
abstract：:The effect of prostaglandin E1 (PGE1) on local cerebral blood flow (LCBF) and carbon dioxide reactivity (CO2R) was studied during cerebral aneurysm surgery for subarachnoid haemorrhage in 24 patients under neuroleptanaesthesia. Eleven patients had good neurological status (Hunt and Kosnik grade I: group A) and 13 pati...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/68.3.268
更新日期：1992-03-01 00:00:00
abstract：:The effects of ventilation with 30% and 100% oxygen were investigated on the circulatory and electrocardiographic response to electroconvulsive therapy (ECT) in 12 patients during 40 treatments. Administration of 30% oxygen resulted in a 25% decrease in seizure duration compared with 100% oxygen (P less than 0.0125). ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/61.5.593
更新日期：1988-11-01 00:00:00
abstract：:The insufflation of oxygen at 1 litre kg-1 min-1 via two endobronchial catheters (called continuous flow ventilation (CFV)) maintained a normal PaCO2 and a constant PaO2 in anaesthetized paralysed dogs and in five out of seven cats. In two cats with a high carbon dioxide production, CFV failed to maintain carbon dioxi...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/58.5.544
更新日期：1986-05-01 00:00:00
abstract：BACKGROUND:Moderate to deep sedation has been recommended during endoscopic submucosal dissection (ESD). However, it is often accompanied by adverse events such as respiratory depression or aspiration pneumonia. This study investigated the respiratory complications and ESD outcomes of two sedation protocols: moderate s...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeu555
更新日期：2015-07-01 00:00:00
abstract：:Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/62.2.194
更新日期：1989-02-01 00:00:00
abstract：BACKGROUND:Paradoxical excitement response during sedation consists of loss of affective control and abnormal movements. Chronic alcohol abuse has been proposed as a predisposing factor despite lack of supporting evidence. Because alcohol and propofol have a common site of action, we postulated that paradoxical excitem...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aer275
更新日期：2011-12-01 00:00:00
