Effect of desflurane at less than 1 MAC on QT interval prolongation induced by tracheal intubation.

abstract：:In clinical use, the concentrations of local anaesthetics at the site of action are unknown. With the method described here, concentrations of local anaesthetics can be predetermined and kept constant at the site of action. In six volunteers, a blister was raised on the ventral surface of the forearm. After removal of...

journal_title：British journal of anaesthesia

authors： Wiesemes R,Klement W,Novotny GE,Lipfert P

更新日期：1993-05-01 00:00:00

abstract：:Maternal haemorrhage is the leading cause of preventable maternal death worldwide and encompasses antepartum, intrapartum, and postpartum bleeding. This review highlights factors that predispose to severe bleeding, its management, and the most recent treatment and guidelines. Advances in obstetric care have provided p...

journal_title：British journal of anaesthesia

authors： Walfish M,Neuman A,Wlody D

更新日期：2009-12-01 00:00:00

abstract：:We have measured in a double-blind study the changes in intraocular pressure (IOP) in 40 consecutive patients (pretreated with fentanyl or alfentanil) who received suxamethonium and tracheal intubation. Although IOP increased significantly following administration of suxamethonium, mean IOP in both groups remained sig...

journal_title：British journal of anaesthesia

authors： Sweeney J,Underhill S,Dowd T,Mostafa SM

更新日期：1989-12-01 00:00:00

abstract：:A total of 1442 patients who had major gynaecological surgery were recruited into three multicentre studies using a standard general anaesthetic technique in order to assess the efficacy of various doses of orally administered ondansetron in the prevention of postoperative nausea and vomiting. A total of 1257 patients...

journal_title：British journal of anaesthesia

authors： Haigh CG,Kaplan LA,Durham JM,Dupeyron JP,Harmer M,Kenny GN

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:This study evaluated the A-Line Autoregressive Index (AAI) response to surgical stimulation during lumbar arthrodesis, as an estimate of the anti-nociceptive component of a Bispectral Index (BIS) guided anaesthesia combined with epidural analgesia. METHODS:An epidural catheter was inserted in 23 patients al...

journal_title：British journal of anaesthesia

authors： Bonhomme V,Llabres V,Dewandre PY,Brichant JF,Hans P

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:The molecular actions underlying the clinical effects of inhaled anaesthetics such as sevoflurane and isoflurane are not fully understood. Unexpected observations in positron emission tomography (PET) studies with [11C]AZD9272, a metabotropic glutamate receptor 5 (mGluR5) radioligand with possible affinity f...

journal_title：British journal of anaesthesia

authors： Varnäs K,Finnema SJ,Johnström P,Arakawa R,Halldin C,Eriksson LI,Farde L

更新日期：2021-01-01 00:00:00

abstract：:Effects of ageing were studied on the neural blockade and the pharmacokinetics after subarachnoid administration of 0.5% bupivacaine 3 ml in 8% glucose in two groups of 15 male patients, between 20 and 55 yr and older than 55 yr, respectively. The blockade was performed with the patient in the sitting position. Two mi...

journal_title：British journal of anaesthesia

authors： Veering BT,Burm AG,Spierdijk J

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to explore difficulties at work from anaesthetists' own perspective and to examine how anaesthetists handle and cope with situations that are perceived as difficult and potentially stressful. METHODS:Two sets of interviews were conducted with 19 specialist anaesthetists in Sweden. ...

journal_title：British journal of anaesthesia

authors： Larsson J,Rosenqvist U,Holmström I

更新日期：2007-10-01 00:00:00

abstract：:Blood loss and the frequency of vomiting were assessed at 88 spontaneous vertex deliveries. An i.v. injection of oxytocin 10 u was as effective as ergometrine 0.5 mg in controlling bleeding from the uterus after delivery. The continuous infusion of a dilute solution of oxytocin in the first stage of labour was not fol...

journal_title：British journal of anaesthesia

authors： Moir DD,Amoa AB

更新日期：1979-02-01 00:00:00

abstract：:The problems of selection of tracheal tubes, and the need for a rationale, are outlined. Tracheal tubes of 7.5 mm and 8.5 mm i.d. are recommended for female and male patients, respectively. Tracheal size was determined using high pressure-low volume cuffs as measuring devices. The average diameter of the cuff at seal ...

journal_title：British journal of anaesthesia

authors： Chandler M,Crawley BE

更新日期：1986-01-01 00:00:00

abstract：:An animal model was established to study the toxic effects of hyperoxia and the consequent changes in intracellular antioxidant status. Superoxide dismutase, catalase and glutathione peroxidase activities were measured in erythrocytes, liver and lung, in addition to cellular glutathione concentrations and its associat...

journal_title：British journal of anaesthesia

authors： Webster NR,Toothill C,Cowen PN

更新日期：1987-06-01 00:00:00

abstract：:This was a prospective, non-randomized, multicentre study of rocuronium (Org 9426) in 40 elective Caesarean section patients at full term without fetal distress. Anaesthesia was induced with thiopentone 4-6 mg kg-1 i.v. and rocuronium 0.6 mg kg-1 and maintained with isoflurane and nitrous oxide in oxygen. Monitors inc...

journal_title：British journal of anaesthesia

authors： Abouleish E,Abboud T,Lechevalier T,Zhu J,Chalian A,Alford K

更新日期：1994-09-01 00:00:00

abstract：:We have compared the postoperative morphine requirements and analgesic efficacy of four doses of i.m. ketorolac 30 mg administered 6-hourly with placebo in a double-blind study of patients undergoing major or minor orthopaedic surgery. During the 24-h postoperative study period which began at the end of surgery, patie...

journal_title：British journal of anaesthesia

authors： Kinsella J,Moffat AC,Patrick JA,Prentice JW,McArdle CS,Kenny GN

更新日期：1992-07-01 00:00:00

abstract：:Sleep disordered breathing is a common problem affecting all age groups, particularly in association with certain other medical conditions and syndromes. The pathological consequences of the disorder may be severe, with significant implications for the perioperative management of sufferers. Research into the effects o...

journal_title：British journal of anaesthesia

authors： Loadsman JA,Hillman DR

更新日期：2001-02-01 00:00:00

abstract：:The relative analgesic efficacy and side-effect profile of peripheral nerve blockade (PNB) techniques compared with lumbar epidural analgesia for major knee surgery is unclear. We undertook a systematic review and meta-analysis of all randomized trials comparing epidural analgesia with PNB for major knee surgery. Eigh...

journal_title：British journal of anaesthesia

authors： Fowler SJ,Symons J,Sabato S,Myles PS

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:The second gas effect (SGE) is considered to be significant only during periods of large volume N(2)O uptake (VN(2)O); however, the SGE of small VN(2)O has not been studied. We hypothesized that the SGE of N(2)O on sevoflurane would become less pronounced when sevoflurane administration is started 60 min aft...

journal_title：British journal of anaesthesia

authors： Hendrickx JF,Carette R,Lemmens HJ,De Wolf AM

更新日期：2006-03-01 00:00:00

abstract：:Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system st...

journal_title：British journal of anaesthesia

authors： Fahey MR,Rupp SM,Canfell C,Fisher DM,Miller RD,Sharma M,Castagnoli K,Hennis PJ

更新日期：1985-11-01 00:00:00

abstract：:This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Statistical analysis suggests t...

journal_title：British journal of anaesthesia

authors： Saitoh Y,Kaneda K,Hattori H,Nakajima H,Murakawa M

更新日期：2019-01-01 00:00:00

abstract：:We report a case of massive pulmonary embolism occurring at the time of graft reperfusion in a patient undergoing orthotopic liver transplantation. The clinical diagnosis of pulmonary embolus was aided by on-table echocardiography. Cardiopulmonary bypass and surgical embolectomy prevented her death. We discuss the dif...

journal_title：British journal of anaesthesia

authors： Manji M,Isaac JL,Bion J

更新日期：1998-05-01 00:00:00

abstract：:Loss of resistance dorsal to the ligamentum flavum was recorded in 10 of 16 patients aged 43--75 yr whilst performing extradural anaesthesia at the L2--3 interspace via the midline approach. Degeneration of the interspinous ligament with cavity formation is observed frequently in the elderly and may account for false ...

journal_title：British journal of anaesthesia

authors： Sharrock NE

更新日期：1979-03-01 00:00:00

abstract：:We conducted a randomized, double-blind comparison of 8% sevoflurane and propofol as induction agents for day-case cystoscopy in 102 patients. All patients received an i.v. cannula and breathed oxygen 5 litre min-1. Anaesthesia was induced with propofol i.v. or inhalation of 8% sevoflurane and 10% Intralipid (as a pla...

journal_title：British journal of anaesthesia

authors： Thwaites A,Edmends S,Smith I

更新日期：1997-04-01 00:00:00

abstract：:We have examined the effect of isoflurane, halothane and fentanyl on heart rate variability (HRV) using power spectral analysis (PSA). Forty patients were allocated randomly to receive one of four anaesthetic techniques. Anaesthesia was induced with propofol 2 mg kg-1 and all patients breathed a mixture of 66% nitrous...

journal_title：British journal of anaesthesia

authors： Galletly DC,Westenberg AM,Robinson BJ,Corfiatis T

更新日期：1994-02-01 00:00:00

abstract：:The influence of sodium nitroprusside (SNP) on mitochondrial respiration was examined in rat liver mitochondria. The addition of SNP 1 mmol litre-1 during state 3 respiration inhibited the oxygen uptake by 63.4%. A mixture of SNP 1 mmol litre-1 and glutathione (GSH) 1 mmol litre-1 inhibited the oxygen uptake more mark...

journal_title：British journal of anaesthesia

authors： Nakamura S,Shin T,Hirokata Y,Shigematsu A

更新日期：1977-12-01 00:00:00

abstract：:Cardioventilatory coupling (CVC) is the temporal coherence of respiratory and cardiac rhythms. We have suggested that this coherence is the result of triggering of inspiratory onset by a preceding cardiovascular afferent. One implication of this triggering hypothesis is that coupling should only exist under conditions...

journal_title：British journal of anaesthesia

authors： Larsen PD,Trent EL,Galletly DC

更新日期：1999-04-01 00:00:00

abstract：:A case of an infant receiving orthotopic heart transplantation with over-sized donor heart was reported. Left lower pulmonary venous obstruction after sternotomy closure was detected by transoesophageal echocardiography (TOE) and the decision to delay sternal closure was made and the clinical outcome was very satisfac...

journal_title：British journal of anaesthesia

authors： Lin CP,Chan KC,Chou YM,Wang MJ,Tsai SK

更新日期：2002-04-01 00:00:00

abstract：:We have compared the effects of progressive (30% and 60%) in vitro haemodilution with hydroxyethyl starch (HES), gelatin (GEL) and albumin (ALB) with haemodilution using 0.9% saline in 96 patients by thrombelastography. Haemodilution with HES, GEL and ALB significantly (P < 0.05) compromised coagulation time (k), angl...

journal_title：British journal of anaesthesia

authors： Egli GA,Zollinger A,Seifert B,Popovic D,Pasch T,Spahn DR

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:There is growing interest in the effect of postoperative analgesics on oncological outcomes after cancer surgery. We investigated the impact of tramadol after breast cancer surgery on recurrence and mortality and explored the mechanism by which tramadol affects cultured breast cancer cells in vitro. METHODS...

journal_title：British journal of anaesthesia

authors： Kim MH,Oh JE,Park S,Kim JH,Lee KY,Bai SJ,Song H,Hwang HJ,Kim DW,Yoo YC

更新日期：2019-12-01 00:00:00

abstract：:Forty-five patients undergoing circumcision were allocated randomly to one of three study groups to compare topical analgesia with dorsal nerve block using the midline or lateral approach. Pain scores, side effects and analgesic requirements were recorded after surgery. Patients who received topical analgesia required...

journal_title：British journal of anaesthesia

authors： Chambers FA,Lee J,Smith J,Casey W

更新日期：1994-10-01 00:00:00

abstract：:The concentrations of volatile hydrocarbons were studied in breath samples from patients before and after anaesthesia. In patients to whom halothane was administered, there was a significant increase in the concentration of isobutene (from 0.43 +/- 0.09 to 4.66 +/- 2.22 nmol litre-1). There was no change in the concen...

journal_title：British journal of anaesthesia

authors： Hempel V,May R,Frank H,Remmer H,Köster U

更新日期：1980-10-01 00:00:00

abstract：:The anaesthetic risks of acromegaly include difficulties in airway management, hypertension, and cardiac, gastrointestinal and renal problems. To estimate the incidence of major complications in this rare group of patients, we reviewed 28 patients with acromegaly who had pituitary tumour excision over a 10-yr period. ...

journal_title：British journal of anaesthesia

authors： Seidman PA,Kofke WA,Policare R,Young M

更新日期：2000-02-01 00:00:00