Continuous infusions of propofol administered to dogs: effects on ICG and propofol disposition.

abstract：:Prolongation of the QT interval of the ECG represents an imbalance in cardiac autonomic function and may predict cardiac arrhythmia. Vagal activity protects against prolongation of the QT interval which may be associated with flattening of the T-wave of the ECG. The changes in QT interval, T-wave amplitude and respira...

journal_title：British journal of anaesthesia

authors： Annila P,Yli-Hankala A,Lindgren L

更新日期：1993-11-01 00:00:00

abstract：:This review describes the laboratory evidence and microvascular mechanisms responsible for the beneficial effects of statins in sepsis. During sepsis, changes occur within the microcirculation including alterations in arteriolar tone influencing blood pressure, adaptations to endothelial cell integrity causing leakage...

journal_title：British journal of anaesthesia

authors： McGown CC,Brookes ZL

更新日期：2007-02-01 00:00:00

abstract：:We report the safe use of remifentanil as part of the anaesthetic technique in a patient undergoing major head and neck surgery who was being treated for depressive illness with the non-specific monoamine oxidase inhibitor (MAOI) phenelzine. ...

journal_title：British journal of anaesthesia

authors： Ure DS,Gillies MA,James KS

更新日期：2000-03-01 00:00:00

abstract：:Twelve hydrocephalic patients undergoing hydrodynamic studies and shunt procedures during general anaesthesia were subjected to short term observations of the cerebrovascular effects of isoflurane. Intraventricular pressure (IVP), arterial pressure (AP); cerebral perfusion pressure (CPP = AP-IVP), end-tidal PCO2, Cere...

journal_title：British journal of anaesthesia

authors： Lundar T,Lindegaard KF,Refsum L,Rian R,Nornes H

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Propofol use during sedation for colonoscopy can result in cardiopulmonary complications. Intravenous lidocaine can alleviate visceral pain and decrease propofol requirements during surgery. We tested the hypothesis that i.v. lidocaine reduces propofol requirements during colonoscopy and improves post-colono...

journal_title：British journal of anaesthesia

authors： Forster C,Vanhaudenhuyse A,Gast P,Louis E,Hick G,Brichant JF,Joris J

更新日期：2018-11-01 00:00:00

abstract：:Raised intracranial pressure (ICP) and low cerebral blood flow (CBF) are associated with ischaemia and poor outcome after brain injury. Therefore, many management protocols target these parameters. This overview summarizes the technical aspects of ICP and CBF monitoring, and their role in the clinical management of br...

journal_title：British journal of anaesthesia

authors： Steiner LA,Andrews PJ

更新日期：2006-07-01 00:00:00

abstract：:We studied 40 elderly patients undergoing cataract surgery. Ten non-insulin-dependent diabetes mellitus (NIDDM) patients received standardized general anaesthesia, 10 NIDDM patients received local anaesthesia using retrobulbar block, 10 non-diabetic control patients received general anaesthesia and 10 non-diabetic con...

journal_title：British journal of anaesthesia

authors： Barker JP,Robinson PN,Vafidis GC,Burrin JM,Sapsed-Byrne S,Hall GM

更新日期：1995-05-01 00:00:00

abstract：:The determination of blood flow, i.e. cardiac output, is an integral part of haemodynamic monitoring. This is a review on noninvasive continuous cardiac output monitoring in perioperative and intensive care medicine. We present the underlying principles and validation data of the following technologies: thoracic elect...

journal_title：British journal of anaesthesia

authors： Saugel B,Cecconi M,Wagner JY,Reuter DA

更新日期：2015-04-01 00:00:00

abstract：:The ventilatory effects of single i.v. doses of morphine 0.1 mg kg-1, pethidine 0.67 mg kg-1 and methadone 0.1 mg kg-1 were compared after ophthalmic surgery in an open, randomized study in 30 children aged 3-8 yr. Ventilatory changes after each drug had distinctive profiles, with appreciable individual variation. Acu...

journal_title：British journal of anaesthesia

authors： Hamunen K

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:ROTEM(®)/TEG(®) (rotational thromboelastometry) assays appear to be useful for the treatment of bleeding trauma patients. However, data on the prevalence and impact of abnormal ROTEM(®) assays are scarce. METHODS:This is a prospective cohort study of blunt trauma patients (Injury Severity Score ≥15 or Glasg...

journal_title：British journal of anaesthesia

authors： Tauber H,Innerhofer P,Breitkopf R,Westermann I,Beer R,El Attal R,Strasak A,Mittermayr M

更新日期：2011-09-01 00:00:00

abstract：:We have compared the ability of naïve intubators to intubate the trachea using a laryngoscope and an intubating laryngeal mask airway (ILMA) after receiving basic training, in a randomized, prospective, crossover study in 60 patients. Ventilation of the lungs via the ILMA was also compared with ventilation with a face...

journal_title：British journal of anaesthesia

authors： Avidan MS,Harvey A,Chitkara N,Ponte J

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Opioid prescribing is increasing worldwide with associated increases in misuse and other harms. We studied variations in national opioid prescription rates, indicators of prescribing quality, co-prescribing of benzodiazepines and relationship with pain severity in Scotland. METHODS:Electronic linkages of op...

journal_title：British journal of anaesthesia

authors： Torrance N,Mansoor R,Wang H,Gilbert S,Macfarlane GJ,Serpell M,Baldacchino A,Hales TG,Donnan P,Wyper G,Smith BH,Colvin L

更新日期：2018-06-01 00:00:00

abstract：:Intravenous dose-response relationships for dimethyl tubocurarine showed that vagal blockade only became appreciable (50-83%) at doses 8-16 times those sufficient for full neuromuscular paralysis in anaesthetized cats (0.0625 mg/kg) and rhesus monkeys (0.125 mg/kg); heart rate was unchanged. Sympathetic function was u...

journal_title：British journal of anaesthesia

authors： Hughes R,Chapple DJ

更新日期：1976-09-01 00:00:00

abstract：:We have investigated the effects of 9.5% and 14.1% MAC concentrations of isoflurane on some psychometric measurements. Both concentrations depressed peak saccadic velocity (P < 0.01), choice reaction time (P < 0.05) and visual analogue scores for sedation (P < 0.05), but not the critical flicker fusion threshold. The ...

journal_title：British journal of anaesthesia

authors： Yoshizumi J,Marshall RW,Sanders LD,Vickers MD

更新日期：1993-12-01 00:00:00

abstract：:The analgesic effects of an identical inguinal field block, performed before or immediately after inguinal herniorrhaphy, were evaluated in 32 healthy patients in a double-blind, randomized study. During surgery, all patients received a light general anaesthesia with thiopentone, alfentanil and nitrous oxide in oxygen...

journal_title：British journal of anaesthesia

authors： Dierking GW,Dahl JB,Kanstrup J,Dahl A,Kehlet H

更新日期：1992-04-01 00:00:00

abstract：:Many indices are used to quantify pulmonary oxygen transfer. Indices that use only measurements from arterial blood and inspired gas assume a constant C(a-v)O2. Though variations in C(a-v)O2 are recognized, indices such as PaO2/FIO2 remain popular and are often considered the best measure of pulmonary oxygen transfer ...

journal_title：British journal of anaesthesia

authors： Nirmalan M,Willard T,Columb MO,Nightingale P

更新日期：2001-04-01 00:00:00

abstract：:We investigated whether low-dose erythromycin (200 mg) given as an oral premedicant altered the residual gastric volume and its acidity in fasted patients at induction of anaesthesia in a single-blinded study. Sixty patients were allocated randomly to receive either an erythromycin tablet (200 mg) or nothing with 10 m...

journal_title：British journal of anaesthesia

authors： Asai T,Murao K,Shingu K

更新日期：2000-12-01 00:00:00

abstract：:Mean venous pressures were measured in 20 patients in whom a catheter, inserted via the external jugular vein, failed to pass centrally. The catheter used had a rounded end and two side holes. Pressures were measured with the patient's head in three different positions. The pressures were compared with the central ven...

journal_title：British journal of anaesthesia

authors： Shah MV,Swai EA,Latto IP

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:To determine the pharmacokinetics (PK) of a new i.v. formulation of paracetamol (Perfalgan) in children ≤15 yr of age. METHODS:After obtaining written informed consent, children under 16 yr of age were recruited to this study. Blood samples were obtained at 0, 15, 30 min, 1, 2, 4, 6, and 8 h after administr...

journal_title：British journal of anaesthesia

authors： Mohammed BS,Engelhardt T,Cameron GA,Cameron L,Hawksworth GM,Hawwa AF,McElnay J,Helms PJ,McLay JS

更新日期：2012-05-01 00:00:00

abstract：:The fate of gallamine triethiodide has been investigated in patients undergoing cholecystectomy with choledochostomy (group I), pelvic operations (group II) and orthopaedic operations (group III). Following a single i.v. injection of gallamine 2.5 mg kg(-1) the disappearance of the drug from the serum occurred in thre...

journal_title：British journal of anaesthesia

authors： Agoston S,Vermeer GA,Kersten UW,Scaf AH

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Acute pulmonary embolism (APE) is an important clinical problem in patients after major surgery and often remains a difficult diagnosis because of unspecific clinical symptoms. Therefore, we investigated the role of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for the detection of APE. MET...

journal_title：British journal of anaesthesia

authors： Winkler BE,Schuetz W,Froeba G,Muth CM

更新日期：2012-12-01 00:00:00

abstract：:We evaluated the use of an inexpensive trans-illuminating light wand for tracheal intubation. Expertise in its use was acquired quickly, thereby providing successful per-oral intubation in all patients who were able to open the mouth, irrespective of the view obtained of the epiglottis and larynx. ...

journal_title：British journal of anaesthesia

authors： Ainsworth QP,Howells TH

更新日期：1989-05-01 00:00:00

abstract：:We have compared the effects of dexmedetomidine and propofol on endocrine, metabolic, inflammatory and cardiovascular responses in patients in the intensive care unit (ICU) after major surgery. Twenty patients who were expected to require 8 h of post-operative sedation and ventilation were allocated randomly to receiv...

journal_title：British journal of anaesthesia

authors： Venn RM,Bryant A,Hall GM,Grounds RM

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Postoperative delirium and cognitive decline are common in elderly surgical patients after non-cardiac surgery. Despite this prevalence and clinical importance, no specific aetiological factor has been identified for postoperative delirium and cognitive decline. In experimental setting in a rat model, nitrou...

journal_title：British journal of anaesthesia

authors： Leung JM,Sands LP,Vaurio LE,Wang Y

更新日期：2006-06-01 00:00:00

abstract：:We tested the hypothesis that premedication with i.m. midazolam decreases core temperature dose-dependently. We studied six male volunteers, in random order, on 3 days: (1) no midazolam administration (control day), (2) midazolam 0.025 mg kg-1 i.m., (3) midazolam 0.075 mg kg-1 i.m. On the first day, subjects were main...

journal_title：British journal of anaesthesia

authors： Matsukawa T,Hanagata K,Ozaki M,Iwashita H,Koshimizu M,Kumazawa T

更新日期：1997-04-01 00:00:00

abstract：:Six patients with airway stenosis were submitted to bronchoscopy under general anaesthesia. Each was ventilated with a gas mixture of 50% oxygen and nitrogen using successively manual jet insufflation (JV) using the Sanders technique at 20 b.p.m., and high frequency jet ventilation (HFJV) at rates of 150, 300 and 500 ...

journal_title：British journal of anaesthesia

authors： Vourc'h G,Fischler M,Michon F,Melchior JC,Seigneur F

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine whether assessment of stroke volume (SV) and measurement of exhaled end-tidal carbon dioxide [Formula: see text] during an end-expiratory occlusion (EEO) test can predict fluid responsiveness in the operating theatre. METHODS:Forty-two subjects monitored by oesop...

journal_title：British journal of anaesthesia

authors： Guinot PG,Godart J,de Broca B,Bernard E,Lorne E,Dupont H

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Investigators planning dose-response studies of neuromuscular blockers have rarely used a priori power analysis to determine the minimal sample size their protocols require. Institutional Review Boards and peer-reviewed journals now generally ask for this information. This study outlines a proposed method fo...

journal_title：British journal of anaesthesia

authors： Kopman AF,Lien CA,Naguib M

更新日期：2011-02-01 00:00:00

abstract：:We have used mivacurium in four myasthenic patients presenting for thymectomy. Supramaximal single twitch stimulation was applied to the ulnar nerve at the wrist and the force of contraction of the adductor pollicis was measured. After an initial bolus dose of 30 micrograms kg-1 (approximately one-fifth of the normal ...

journal_title：British journal of anaesthesia

authors： Paterson IG,Hood JR,Russell SH,Weston MD,Hirsch NP

更新日期：1994-10-01 00:00:00

abstract：:We studied psychomotor performance in 10 healthy volunteers during recovery after a target-controlled infusion of propofol. Choice reaction time, dual task tracking with secondary reaction time and a within-list recognition task were assessed at target blood propofol concentrations of 0.8, 0.4 and 0.2 microgram ml-1. ...

journal_title：British journal of anaesthesia

authors： Grant SA,Murdoch J,Millar K,Kenny GN

更新日期：2000-09-01 00:00:00