Abstract：
:For 6 months after renal transplant serum cholinesterase concentrations were measured in 10 patients. The value decreased in the first 15 days after operation, but was normal thereafter. Liver function tests were normal throughout the study; the cholinesterase changes were independent of immunosuppressive therapy.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Ryan DWdoi
10.1093/bja/51.9.881subject
Has Abstractpub_date
1979-09-01 00:00:00pages
881-4issue
9eissn
0007-0912issn
1471-6771pii
S0007-0912(17)44231-0journal_volume
51pub_type
杂志文章abstract：:In clinical use, the concentrations of local anaesthetics at the site of action are unknown. With the method described here, concentrations of local anaesthetics can be predetermined and kept constant at the site of action. In six volunteers, a blister was raised on the ventral surface of the forearm. After removal of...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/70.5.552
更新日期：1993-05-01 00:00:00
abstract：:We have measured in 38 patients the plasma concentration profile of atracurium and its effect on the electromyographic first response of the train-of-four. One of three techniques was used to supplement anaesthesia with 66% nitrous oxide in oxygen, 0.9% isoflurane (end-tidal), 0.5% halothane (end-tidal) or midazolam 3...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/70.1.38
更新日期：1993-01-01 00:00:00
abstract：:Cardiovascular risk prediction using clinical risk factors is integral to both the European and the American algorithms for preoperative cardiac risk assessment and perioperative management for non-cardiac surgery. We have reviewed these risk factors and their ability to guide clinical decision making. We examine thei...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aer194
更新日期：2011-08-01 00:00:00
abstract：:We have compared, in a randomized, double-blind study, the pharmacokinetics of ropivacaine and bupivacaine during labour. Total and free plasma concentrations of ropivacaine and bupivacaine were measured after the first of two extradural doses. The main dose was 20 mg (test dose) and 30 mg, with a top-up dose of 25 mg...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/79.5.558
更新日期：1997-11-01 00:00:00
abstract：:The analgesic effects of buprenorphine 2 microgram/kg--1 and 8 microgram. kg--1 were compared with those of pethidine 1 mg. kg--1 and pentazocine 0.6 mg.kg--1 in 172 patients recovering from surgery. The drugs were given by i.m. injection in the period immediately after operation and the quality of pain relief was ass...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/49.9.913
更新日期：1977-09-01 00:00:00
abstract：:The calculation of pharmacokinetic parameters after a bolus injection of fentanyl allowed an i.v. infusion scheme which guarantees analgesia for the entire duration of surgery, with the advantage of steady plasma concentration and body content. In the initial phase after bolus injection, the serum concentration decrea...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/52.10.1021
更新日期：1980-10-01 00:00:00
abstract：:We have investigated the effect of four doses of remifentanil on the incidence of respiratory depression and somatic response at incision. Remifentanil was administered as a loading dose of 0.125, 0.25, 0.375 or 0.5 microgram kg-1 and at a maintenance infusion rate of 0.025, 0.05, 0.075 or 0.1 microgram kg-1 min-1, re...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1093/bja/80.4.509
更新日期：1998-04-01 00:00:00
abstract：:We studied 325 patients undergoing elective noncardiac surgery who had preoperative ambulatory ECG monitoring performed for a duration of 5130 h (range 8-24 h; mean 15.8 h). Sixty-four subjects (20%) had one or more episodes of ST segment depression consistent with myocardial ischaemia. Of all preoperative cardiovascu...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/73.5.574
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND:Fluid administration to increase stroke volume index (SVi) is a cornerstone of haemodynamic resuscitation. We assessed the accuracy of SVi variation during a calibrated abdominal compression manoeuvre (ΔSVi-CAC) to predict fluid responsiveness in children. METHODS:Patients younger than 8 yr with acute circu...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2018.06.030
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Myocardial potassium channels are complexes formed by different subunits. The subunit composition may influence the cardiotoxic action of local anaesthetics. The effects of amide local anaesthetics on HERG channels co-expressed with the putative subunit MiRP1 have not been established. It is also unclear if ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeh026
更新日期：2004-01-01 00:00:00
abstract：:This is the report of a 55-yr-old female who developed severe myotonia and dystonia after general anaesthesia. Before starting on gabapentin therapy for a neuropathic pain condition, she had undergone numerous uneventful general anaesthetics. Since receiving treatment with gabapentin, she has experienced severe moveme...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aem130
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Prediction models to identify parturients who experience protracted pain, prolonged opioid use, and delayed self-assessed functional recovery are currently inadequate. METHODS:For this study, 213 nulliparous women who planned vaginal delivery were enrolled and assessed daily until they completed three outco...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2018.04.033
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:This study evaluated the A-Line Autoregressive Index (AAI) response to surgical stimulation during lumbar arthrodesis, as an estimate of the anti-nociceptive component of a Bispectral Index (BIS) guided anaesthesia combined with epidural analgesia. METHODS:An epidural catheter was inserted in 23 patients al...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/ael004
更新日期：2006-03-01 00:00:00
abstract：:The majority of patients with acute respiratory distress syndrome (ARDS) require mechanical ventilation. This support provides time for the lungs to heal, but the adverse effects of mechanical ventilation significantly influence patient outcome. Traditionally, these were ascribed to mechanical effects, such as haemody...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aeh031
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:A recent study showed that the noble gas helium induces early myocardial preconditioning. Cyclooxygenase-2 (COX-2) has been shown to be an important mediator in the signal transduction of late preconditioning. In the present study, we investigated whether helium induces late preconditioning in a concentratio...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aep042
更新日期：2009-05-01 00:00:00
abstract：:We studied 20 patients undergoing thoracotomy, in a double-blind, placebo-controlled crossover trial of intercostal bupivacaine. Bupivacaine 0.25% was infused at 5 ml h-1 through each of two catheters placed in the intercostal space at operation. Mean (95% confidence limits) 24-h requirements for morphine from a patie...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/70.5.508
更新日期：1993-05-01 00:00:00
abstract：BACKGROUND:Fresh-frozen plasma (FFP) is widely used in critically ill patients, despite a weak evidence base. Factors that influence the decision to transfuse FFP before intravascular catheter insertion are poorly described. METHODS:We undertook a case-controlled study based on a prospective cohort study of 1923 admis...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aes337
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:The minimum alveolar concentration (MAC) is a traditional index of the hypnotic potency of an inhalational anaesthetic. To investigate the anaesthetic as well as the unwanted effects of xenon (Xe) in a swine model, it is useful to know MAC(Xe). METHODS:The study was performed using ten swine (weight 27.8-35...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeh077
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:Descriptions of the pharmacokinetics and metabolism of morphine and its metabolites in young children are scant. Previous studies have not differentiated the effects of size from those related to age during infancy. METHODS:Postoperative children 0-3 yr old were given an intravenous loading dose of morphine...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/aeh042
更新日期：2004-02-01 00:00:00
abstract：:Using in vivo microdialysis, we have investigated the effects of propofol on acetylcholine (ACh) release from various regions of the rat brain. Propofol 25 and 50 mg kg-1 i.p. decreased basal ACh release from the frontal cortex by 70% and 85%, respectively. Propofol 25 and 50 mg kg-1 i.p. decreased basal ACh release f...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/80.5.644
更新日期：1998-05-01 00:00:00
abstract：:An oxygen consuming lung model was used for evaluation and validation of a technique for metabolic gas exchange measurements during controlled ventilation. The technique comprised a Servo 900 C ventilator (Siemens) and separate oxygen and carbon dioxide analysers (Beckman). Measurements of oxygen consumption and carbo...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/64.3.311
更新日期：1990-03-01 00:00:00
abstract：:We have studied the pharmacokinetics and pharmacodynamics of alfentanil, fentanyl and sufentanil together with propofol in patients undergoing coronary artery bypass graft surgery (CABG). Sixty patients (age 40-73 yr, 56 male) were assigned randomly to receive alfentanil, fentanyl or sufentanil and propofol. Plasma co...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/85.4.533
更新日期：2000-10-01 00:00:00
abstract：:The trachea of a man who had cut his own throat was successfully intubated using a fibreoptic laryngoscope after attempts at conventional oral intubation had failed. The advantages of the fibreoptic instrument and the method of use in such an injury are discussed. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/50.5.511
更新日期：1978-05-01 00:00:00
abstract：BACKGROUND:As general anaesthesia may compromise the immune system, it has been hypothesized that latent varicella-zoster virus is more likely to be reactivated and cause herpes zoster in mothers after Caesarean deliveries under general anaesthesia. Our study was thus aimed at investigating the risk of herpes zoster am...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aer386
更新日期：2012-02-01 00:00:00
abstract：:The effect of the combination of opiates and hypnotics on bispectral index (BIS) is unclear. This double-blind placebo-controlled trial investigated the effect on BIS and sedation of different infusion doses of remifentanil combined with a steady infusion of propofol. Forty patients initially received a target-control...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/oxfordjournals.bja.a013474
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Preoperative anaemia affects one third of patients undergoing cardiac surgery and is associated with increased mortality and morbidity. Although it is recommended that perioperative teams should identify and treat patients with preoperative anaemia before surgery, introducing new treatment protocols can be c...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bja.2019.11.023
更新日期：2020-03-01 00:00:00
abstract：:Day-case anaesthesia requires rapidly eliminated anaesthetics which are relatively expensive. This multinational, multicentre European study assessed the relative costs of propofol or sevoflurane anaesthesia in 211 patients. Anaesthesia was induced and maintained with propofol in group 1, with propofol and sevoflurane...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1093/bja/83.4.564
更新日期：1999-10-01 00:00:00
abstract：BACKGROUND:Opioid prescribing is increasing worldwide with associated increases in misuse and other harms. We studied variations in national opioid prescription rates, indicators of prescribing quality, co-prescribing of benzodiazepines and relationship with pain severity in Scotland. METHODS:Electronic linkages of op...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2018.02.022
更新日期：2018-06-01 00:00:00
abstract：:Bilateral superior laryngeal nerve block was combined with topical application of local anaesthetic 140 times in 135 patients to anaesthetize the upper airway and facilitate tracheal intubation, laryngeal instrumentation, or to diminish the response to the endotracheal tube, in a patient already intubated. The techniq...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/53.10.1055
更新日期：1981-10-01 00:00:00
abstract：:This editorial looks at some of the various anesthesias used during pregnancy termination. Trichloroethylene, often a popular substitute for halothane, has been subjected to little evaluation. Only clinical study however, can actually establish the significance of myometrial depressant properties in the pregnant pat...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/52.8.711
更新日期：1980-08-01 00:00:00
