Infusion model for fentanyl based on pharmacokinetic analysis.

abstract：BACKGROUND:Serum vascular endothelial growth factor-C (VEGF-C), transforming growth factor-β (TGF-β), and interleukin (IL)-6 promote angiogenesis and metastases in colon cancer. We hypothesized that patients who received propofol-epidural anaesthesia (PEA) would exhibit decreases in VEGF-C, TGF-β, and IL-6 and an incre...

journal_title：British journal of anaesthesia

authors： Xu YJ,Chen WK,Zhu Y,Wang SL,Miao CH

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:This study was undertaken to compare the effects of general anaesthesia (GA) and spinal anaesthesia (SA) on the need for postoperative hospitalization and early postoperative comfort in patients undergoing fast-track total knee arthroplasty (TKA). METHODS:One hundred and twenty subjects were randomly alloca...

journal_title：British journal of anaesthesia

authors： Harsten A,Kehlet H,Toksvig-Larsen S

更新日期：2013-09-01 00:00:00

abstract：:A modification of an i.v. regional anaesthesia (IVRA) technique is described in which the arm is re-exsanguinated before surgery (re-IVRA). IVRA and re-IVRA were compared for quality of operative field, sensory and motor block, quality of analgesia and blood concentrations of prilocaine, lignocaine and mepivacaine in ...

journal_title：British journal of anaesthesia

authors： Rawal N,Hallén J,Amilon A,Hellstrand P

更新日期：1993-03-01 00:00:00

abstract：:There is compelling evidence that preconditioning occurs in humans. Experimental studies with potential clinical implications as well as clinical studies evaluating ischaemic, pharmacological and anaesthetic cardiac preconditioning in the perioperative setting are reviewed. These studies reveal promising results. Howe...

journal_title：British journal of anaesthesia

authors： Zaugg M,Lucchinetti E,Garcia C,Pasch T,Spahn DR,Schaub MC

更新日期：2003-10-01 00:00:00

abstract：:Forty patients (age range 60-79 yr) undergoing transurethral surgery were allocated randomly to receive 0.5% plain bupivacaine 4 ml at the L2-3 (n = 20) or L4-5 (n = 20) space. The solution was injected over 30 s with the patient in the sitting position. The patient was kept sitting for 2 min, then placed supine and, ...

journal_title：British journal of anaesthesia

authors： Olsen KH,Nielsen TH,Kristoffersen E,Husegaard HC,Wernberg M,Dørup J

更新日期：1990-02-01 00:00:00

abstract：:Artery-to-muscle (A-M) onset time for five neuromuscular blocking agents was studied in 50 female patients under light endotracheal anaesthesia. Circulation to the right arm was occluded by a tourniquet and released 1 min after the injection i.v. into the left arm of a myoneural blocking drug. Muscle twitches were rec...

journal_title：British journal of anaesthesia

authors： Minsaas B,Stovner J

更新日期：1980-04-01 00:00:00

abstract：:We have examined the extradural space using a flexible extraduroscope in 74 patients undergoing extradural anaesthesia at the L2-3 interspace. Extraduroscopy showed that the extradural space becomes widely patent and the fatty tissue in the extradural space diminishes with increasing age. We postulate that these age-r...

journal_title：British journal of anaesthesia

authors： Igarashi T,Hirabayashi Y,Shimizu R,Saitoh K,Fukuda H,Mitsuhata H

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Midlatency auditory evoked potentials (MLAEP) are a promising tool for monitoring suppression of sensory processing during anaesthesia and might help to avoid awareness. MLAEP in children are different to those in adults and the exact changes during general anaesthesia are unknown. METHODS:In 49 children of...

journal_title：British journal of anaesthesia

authors： Daunderer M,Feuerecker MS,Scheller B,Pape NB,Schwender D,Kuhnle GE

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Anaesthetics blunt neuronal responses to noxious stimulation, including effects on electroencephalographic (EEG) responses. It is unclear how anaesthetics differ in their ability to modulate noxious stimulation-evoked EEG activation. We investigated the actions of propofol and halothane on EEG responses to n...

journal_title：British journal of anaesthesia

authors： Orth M,Barter L,Dominguez C,Atherley R,Carstens E,Antognini JF

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Beta-adrenergic agonists enhance behavioural and electroencephalographic arousal reactions. We explored whether adding esmolol, a short-acting beta(1)-adrenoceptor antagonist, to propofol anaesthesia modified the bispectral index (BIS) during induction of anaesthesia and orotracheal intubation. METHODS:Fift...

journal_title：British journal of anaesthesia

authors： Menigaux C,Guignard B,Adam F,Sessler DI,Joly V,Chauvin M

更新日期：2002-12-01 00:00:00

abstract：:Plain bupivacaine 0.5% or 0.75% was injected intrathecally in four groups of 10 patients. Group A received 0.75% bupivacaine 2.7 ml at L3/4, group B 0.5% bupivacaine 4 ml at L3/4, group C 0.75% bupivacaine 2.7 ml at L2/3 and group D 0.75% bupivacaine 2 ml at L3/4. A very wide range of height of block was found in each...

journal_title：British journal of anaesthesia

authors： Logan MR,McClure JH,Wildsmith JA

更新日期：1986-03-01 00:00:00

abstract：:Ketamine, as the sole anaesthetic agent, was assessed in a double-blind study of 135 female patients who underwent laparoscopic sterilization. The patients were allocated randomly to one of four groups according to the type (pentobarbitone or droperidol) and route (i.v. or i.m.) of premedication. In addition all the p...

journal_title：British journal of anaesthesia

authors： Figallo EM,Casali H,McKenzie R,Tantisira B,Wadhwa RK,Taylor FH

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Days alive and out of hospital (DAH) has been proposed as a pragmatic outcome measure of surgical quality. However, there is a lack of procedure specific data or data within an optimised fast-track protocol. Furthermore, information about influence of follow-up duration and types of complications on DAH is l...

journal_title：British journal of anaesthesia

authors： Jørgensen CC,Petersen PB,Kehlet H,Lundbeck Foundation Center for Fast-track Hip and Knee Replacement Collaborative Group.

更新日期：2019-11-01 00:00:00

abstract：:A recently installed anti-pollution system, initially designed to function in a passive mode, was evaluated, but found to be inconstant in its performance. A simple method of making the system active is described and evaluated. ...

journal_title：British journal of anaesthesia

authors： Asbury AJ,Hancox AJ

更新日期：1977-05-01 00:00:00

abstract：:The effect of gas leakage around an uncuffed tracheal tube on the performance of Heat and Moisture Exchangers (HME) was examined experimentally. Such leaks were shown to cause measurable decreases in the humidity output and efficiency of HME. The magnitude of the decrease in humidity output was shown to be dependent u...

journal_title：British journal of anaesthesia

authors： Tilling SE,Hayes B

更新日期：1987-09-01 00:00:00

abstract：:Recommendations for resuscitation of patients in early haemorrhagic shock, with active ongoing bleeding, have evolved in recent years. This review covers current theories of the pathophysiology of shock and recommended treatments, including damage control surgery, deliberate hypotensive management, administration of a...

journal_title：British journal of anaesthesia

authors： Dutton RP

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the prevalence of postoperative nausea and vomiting (PONV) after fast-track cardiac anaesthesia, risk factors for PONV and its influence on the length of stay in the intensive care unit (ICU). METHODS:A prospective study was performed in the cardiothoracic ICU (CTICU) ...

journal_title：British journal of anaesthesia

authors： Kogan A,Eidelman LA,Raanani E,Orlov B,Shenkin O,Vidne BA

更新日期：2003-08-01 00:00:00

abstract：:We calculated oxygen consumption by the reverse Fick principle (cVO2) using cardiac output measured with a new technique of continuous thermal dilution and compared these values with measurements made at the same time using a gas exchange method (mVO2). We studied nine patients in a stable condition after cardiac surg...

journal_title：British journal of anaesthesia

authors： Bizouarn P,Blanloeil Y,Pinaud M

更新日期：1995-12-01 00:00:00

abstract：:The speeds of onset of pancuronium, atracurium and vecuronium are increased by prior administration of magnesium sulphate. A prospective, randomized, double-blind, controlled, clinical study was performed to examine the effects of prior i.v. administration of magnesium sulphate 60 mg kg-1 on the neuromuscular blocking...

journal_title：British journal of anaesthesia

authors： Kussman B,Shorten G,Uppington J,Comunale ME

更新日期：1997-07-01 00:00:00

abstract：:A method for the assessment and management of factors both causing and maintaining a primary metabolic alkalosis is presented. During a 2-year period 65 patients with metabolic alkalosis were treated with saline and potassium chloride infusions. In four patients the alkalosis was refractory and required additional the...

journal_title：British journal of anaesthesia

authors： Worthley LI

更新日期：1977-08-01 00:00:00

abstract：:Interest in the use of psychosocial interventions to help older adults manage pain is growing. In this article, we review this approach. The first section reviews the conceptual background for psychosocial interventions with a special emphasis on the biopsychosocial model of pain. The second section highlights three p...

journal_title：British journal of anaesthesia

authors： Keefe FJ,Porter L,Somers T,Shelby R,Wren AV

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Using a carrageenan inflammation rat model, we evaluated two experimental approaches to prolong sciatic nerve block on contralateral hyperalgesia. Method. We performed ipsilateral sciatic nerve block on the inflamed hind paw with bupivacaine-loaded microspheres suspended in dexamethasone (bupivacaine 12.5 mg...

journal_title：British journal of anaesthesia

authors： Estebe JP,Gentili ME,Le Corre P,Leduc C,Moulinoux JP,Ecoffey C

更新日期：2004-11-01 00:00:00

abstract：:We have documented the changes in gas exchange, haemodynamic state and associated physiological variables which occurred after graft reperfusion in 20 patients undergoing uncomplicated orthotopic liver transplantation. Gas exchange was measured during constant ventilation using a metabolic monitor. After reperfusion, ...

journal_title：British journal of anaesthesia

authors： Walsh TS,Hopton P,Garden OJ,Lee A

更新日期：1998-09-01 00:00:00

abstract：:Percutaneous dilatational tracheostomy (PDT) is associated with a number of life-threatening complications. We present a case of massive and fatal arterial haemorrhage that occurred in the intensive care unit during an elective PDT on an 86-year-old woman following earlier evacuation of a traumatic subdural haematoma....

journal_title：British journal of anaesthesia

authors： Shlugman D,Satya-Krishna R,Loh L

更新日期：2003-04-01 00:00:00

abstract：:Blood loss and the frequency of vomiting were assessed at 88 spontaneous vertex deliveries. An i.v. injection of oxytocin 10 u was as effective as ergometrine 0.5 mg in controlling bleeding from the uterus after delivery. The continuous infusion of a dilute solution of oxytocin in the first stage of labour was not fol...

journal_title：British journal of anaesthesia

authors： Moir DD,Amoa AB

更新日期：1979-02-01 00:00:00

abstract：:A series of 443 spinal anaesthetics is described. The procedures included operative vaginal delivery, removal of retained placenta and a miscellaneous group common to most obstetric units. Failure to provide effective relief of pain occurred in 5.2% of patients. There was one potentially serious complication, but with...

journal_title：British journal of anaesthesia

authors： Crawford JS

更新日期：1979-06-01 00:00:00

abstract：:I.V. fluid therapy plays a fundamental role in the management of hospitalized patients. While the correct use of i.v. fluids can be lifesaving, recent literature demonstrates that fluid therapy is not without risks. Indeed, the use of certain types and volumes of fluid can increase the risk of harm, and even death, in...

journal_title：British journal of anaesthesia

authors： Hoste EA,Maitland K,Brudney CS,Mehta R,Vincent JL,Yates D,Kellum JA,Mythen MG,Shaw AD,ADQI XII Investigators Group.

更新日期：2014-11-01 00:00:00

abstract：:The pressor and catecholamine responses to laryngoscopy and intubation were studied in nine patients with pregnancy-induced hypertension (PIH) and in eight normotensive controls. Five of the PIH patients had received oral labetalol as antihypertensive therapy. Mean arterial pressure (MAP) increased significantly from ...

journal_title：British journal of anaesthesia

authors： Lavies NG,Meiklejohn BH,May AE,Achola KJ,Fell D

更新日期：1989-10-01 00:00:00

abstract：:Systolic pressure variation (SPV) and its dDown component have been shown to be sensitive factors in estimating intravascular volume in patients undergoing mechanical ventilation. In this study, ventilation-induced changes in pulse oximeter plethysmographic waveform were evaluated after removal and after reinfusion of...

journal_title：British journal of anaesthesia

authors： Shamir M,Eidelman LA,Floman Y,Kaplan L,Pizov R

更新日期：1999-02-01 00:00:00

abstract：:A study of core temperature monitoring during general anesthesia indicates that this can be introduced as a routine procedure in order to reduce mortality from malignant hyperpyrexia. The temperature profiles of 2410 patients are presented. Both mean rectal and mean oesophageal temperatures decreased during general an...

journal_title：British journal of anaesthesia

authors： Crocker BD,Okumura F,McCuaig DI,Denborough MA

更新日期：1980-12-01 00:00:00