Anaesthetics and cardiac preconditioning. Part II. Clinical implications.

Abstract:

:There is compelling evidence that preconditioning occurs in humans. Experimental studies with potential clinical implications as well as clinical studies evaluating ischaemic, pharmacological and anaesthetic cardiac preconditioning in the perioperative setting are reviewed. These studies reveal promising results. However, there are conflicting reports on the efficacy of preconditioning in the diseased and aged myocardium. In addition, many anaesthetics and a significant number of perioperatively administered drugs affect the activity of cardiac sarcolemmal and mitochondrial K(ATP) channels, the end-effectors of cardiac preconditioning, and thereby markedly modulate preconditioning effects in myocardial tissue. Although these modulatory effects on K(ATP) channels have been investigated almost exclusively in laboratory investigations, they may have potential implications in clinical medicine. Important questions regarding the clinical utility and applicability of perioperative cardiac preconditioning remain unresolved and need more experimental work and randomized controlled clinical trials.

journal_name

Br J Anaesth

authors

Zaugg M,Lucchinetti E,Garcia C,Pasch T,Spahn DR,Schaub MC

doi

10.1093/bja/aeg206

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

566-76

issue

4

eissn

0007-0912

issn

1471-6771

pii

S0007-0912(17)36678-3

journal_volume

91

pub_type

杂志文章,评审
  • Retraction notice to "Monitoring of neuromuscular block after administration of vecuronium in patients with diabetes mellitus" [Br J Anaesth 2003; 90: 480-486].

    abstract::This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief of British Journal of Anaesthesia. The study is retracted for the following reasons: Statistical analysis suggests t...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,撤回出版物

    doi:10.1016/j.bja.2018.11.007

    authors: Saitoh Y,Kaneda K,Hattori H,Nakajima H,Murakawa M

    更新日期:2019-01-01 00:00:00

  • Effect of different kinds of premedication on the induction properties of midazolam.

    abstract::The effects of different premedication (i.m. and i.v.) on the usefulness of midazolam or thiopentone as induction agents for minor surgery was studied in 194 women undergoing either dilatation and curettage or explorative fractionate curettage. Midazolam appeared to produce light sedation which required powerful preme...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章

    doi:10.1093/bja/54.5.507

    authors: Kanto J,Sjövall S,Vuori A

    更新日期:1982-05-01 00:00:00

  • Neurological biomarkers in the perioperative period.

    abstract::The rapid detection and evaluation of patients presenting with perioperative neurological dysfunction is of great clinical relevance. Biomarkers have been defined as biological molecules that can be used as an indicator of new onset or progression of a biological process or effect of treatment. Biomarkers have become ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aer338

    authors: Cata JP,Abdelmalak B,Farag E

    更新日期:2011-12-01 00:00:00

  • Meta-analytic comparison of prophylactic antiemetic efficacy for postoperative nausea and vomiting: propofol anaesthesia vs omitting nitrous oxide vs total i.v. anaesthesia with propofol.

    abstract::Data from two published and one new meta-analysis were reviewed to compare the antiemetic efficacy of three different anaesthetic regimens: (i) propofol anaesthesia compared with another anaesthetic (control); (ii) anaesthesia without nitrous oxide compared with the same anaesthetic with nitrous oxide (control); (iii)...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析

    doi:10.1093/bja/78.3.256

    authors: Tramèr M,Moore A,McQuay H

    更新日期:1997-03-01 00:00:00

  • Use of di-isopropyl phenol as main agent for short procedures.

    abstract::The use of di-isopropyl phenol (Diprivan) for induction of anaesthesia was assessed in doses ranging from 1 to 3 mg kg-1. With less than 1.75mg kg-1 not all patients were anaesthetized; 2.0 mg kg-1 appeared to be a satisfactory induction dose. Involuntary muscle movement, cough and hiccup at induction were rare with a...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/53.11.1197

    authors: Briggs LP,Clarke RS,Dundee JW,Moore J,Bahar M,Wright PJ

    更新日期:1981-11-01 00:00:00

  • The history of controlled hypotension.

    abstract::As the physiology of deliberate hypotension has been unravelled, and as each new pharmacological agent has become available which either depresses or blocks peripheral vascular tone, depresses myocardial performance, or interferes with the conducting tissues within the myocardium, its possible incorporation into the a...

    journal_title:British journal of anaesthesia

    pub_type: 历史文章,杂志文章

    doi:10.1093/bja/47.7.745

    authors: Leigh JM

    更新日期:1975-07-01 00:00:00

  • Sedation following cardiac surgery: evaluation of alfentanil and morphine in the presence of a computerized closed loop arterial pressure controller.

    abstract::Forty patients who had undergone coronary artery graft surgery and who required vasodilator therapy for postoperative hypertension were given infusions of either alfentanil or morphine together with bolus doses of midazolam for sedation and analgesia while ventilation was controlled artificially. Sodium nitroprusside ...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/61.6.669

    authors: McMenemin IM,Church JA,Kenny GN

    更新日期:1988-12-01 00:00:00

  • Beta-adrenergic blockade and the metabolic response to surgery.

    abstract::The effect of the administration of propranolol 0.15 mg per kg body weight i.v. on the metabolic response to pelvic surgery was compared with results in similar patients who had not received propranolol. The only significant difference between the two groups was a lower plasma insulin concentration in the beta-blockad...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/52.12.1231

    authors: Cooper GM,Paterson JL,Mashiter K,Hall GM

    更新日期:1980-12-01 00:00:00

  • Isoflurane impairs odour discrimination learning in rats: differential effects on short- and long-term memory.

    abstract:BACKGROUND:Anaesthetics suppress the formation of lasting memories at concentrations that do not suppress perception, but it is unclear which elements of the complex cascade leading from a conscious experience to a lasting memory trace are disrupted. Experiments in conscious humans suggest that subhypnotic concentratio...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer451

    authors: Pearce RA,Duscher P,Van Dyke K,Lee M,Andrei AC,Perouansky M

    更新日期:2012-04-01 00:00:00

  • Early ultrasonographic detection of low-volume intraneural injection.

    abstract:BACKGROUND:Intraneural injection of local anaesthetic agents carries a risk of neurological complications. Early detection of intraneural needle-tip position is very important in the initial phase of injection. Ultrasound (US) characteristics for real-time detection of intraneural injections have been described, but on...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aes208

    authors: Moayeri N,Krediet AC,Welleweerd JC,Bleys RL,Groen GJ

    更新日期:2012-09-01 00:00:00

  • Autotransfusion performed on a patient with cis AB blood group.

    abstract::Cis AB blood group is a rare variant of the AB blood group resulting from inheritance of both A and B genes on one chromosome. It may lead to misclassification in ABO grouping and clinical misdiagnosis as a result of its divergence from the laws of Landsteiner and Mendel. We encountered a case of cis AB blood group, a...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/83.3.491

    authors: Kawahito S,Kitahata H,Kimura H,Tanaka K,Oshita S

    更新日期:1999-09-01 00:00:00

  • Comparison of the laryngoscopy views with the size 1 Miller and Macintosh laryngoscope blades lifting the epiglottis or the base of the tongue in infants and children

    abstract:BACKGROUND:Miller laryngoscope blades are preferred for laryngoscopy in infants and children <2 yr of age. Despite their long history, the laryngeal view with the Miller blade size 1 has never been compared with that with the Macintosh (MAC) blade in children. This prospective, single-blinded, randomized study was desi...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aeu228

    authors: Passi Y,Sathyamoorthy M,Lerman J,Heard C,Marino M

    更新日期:2014-11-01 00:00:00

  • Intraoperative ventilation strategies to prevent postoperative pulmonary complications: a network meta-analysis of randomised controlled trials.

    abstract:BACKGROUND:The debate on lung-protective ventilation strategies for surgical patients is ongoing. Evidence suggests that the use of low tidal volume VT improves clinical outcomes. However, the optimal levels of PEEP and recruitment manoeuvre (RM) strategies incorporated into low VT ventilation remain unclear. METHODS:...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.bja.2019.10.024

    authors: Deng QW,Tan WC,Zhao BC,Wen SH,Shen JT,Xu M

    更新日期:2020-03-01 00:00:00

  • Differential effects of clonidine and dexmedetomidine on gastric emptying and gastrointestinal transit in the rat.

    abstract::We have studied the effect of clonidine, dexmedetomidine and morphine on gastric emptying and gastrointestinal transit in the rat. In one group, each agonist was injected i.p. in 6-12 male Wistar rats. In another group of rats, yohimbine, naloxone or saline was injected with an agonist. At 30 min, radiolabelled saline...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/78.3.301

    authors: Asai T,Mapleson WW,Power I

    更新日期:1997-03-01 00:00:00

  • Incidence of sub-perineural injection using a targeted intracluster supraclavicular ultrasound-guided approach in cadavers.

    abstract:BACKGROUND:Multi-injection targeted intracluster injection ultrasound-guided supraclavicular brachial plexus block has been advocated to provide a faster onset of anaesthesia compared with a double injection technique. By placing the needle within clusters of hypoechoic structures, corresponding to neural tissue, this ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1016/j.bja.2019.01.006

    authors: Retter S,Szerb J,Kwofie K,Colp P,Sandeski R,Uppal V

    更新日期:2019-06-01 00:00:00

  • Lung function after total intravenous anaesthesia or balanced anaesthesia with sevoflurane.

    abstract:BACKGROUND:We investigated the effects of total i.v. anaesthesia (TIVA) and balanced anaesthesia (BAL) with sevoflurane on postoperative lung function in patients undergoing surgery in the prone position. METHODS:Sixty patients, aged 21-60 yr, undergoing elective lumbar disc surgery in the prone position were randomly...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aeq321

    authors: Tiefenthaler W,Pehboeck D,Hammerle E,Kavakebi P,Benzer A

    更新日期:2011-02-01 00:00:00

  • 4-Aminopyridine reversal of fentanyl-induced respiratory depression in normocapnic and hypercapnic patients.

    abstract::Profound postoperative respiratory depression after larger doses of fentanyl was partially reversed by 4-aminopyridine. This reversal was independent of FIO2' suggesting that the response was not dependent upon peripheral chemoreceptor-mediated drive. Similar reversal of fentanyl-induced depression by 4-aminopyridine ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/53.4.373

    authors: Sia RL,Zandstra DF

    更新日期:1981-04-01 00:00:00

  • Tetanic stimulus of ulnar nerve as a predictor of heart rate response to skin incision in propofol remifentanil anaesthesia.

    abstract:BACKGROUND:To study adequate antinociception during general anaesthesia, tetanic stimulus of 5-10 s duration has been used previously as a standardized nociceptive stimulus. However, such stimuli have been found to correlate poorly with intraoperative nociception. We hypothesized that an electrical tetanic stimulus of ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aem200

    authors: Rantanen M,Yppärilä-Wolters H,van Gils M,Yli-Hankala A,Huiku M,Kymäläinen M,Korhonen I

    更新日期:2007-10-01 00:00:00

  • Protective ventilation of patients with acute respiratory distress syndrome.

    abstract::The majority of patients with acute respiratory distress syndrome (ARDS) require mechanical ventilation. This support provides time for the lungs to heal, but the adverse effects of mechanical ventilation significantly influence patient outcome. Traditionally, these were ascribed to mechanical effects, such as haemody...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,评审

    doi:10.1093/bja/aeh031

    authors: Moloney ED,Griffiths MJ

    更新日期:2004-02-01 00:00:00

  • Does motor block related to long-acting brachial plexus block cause patient dissatisfaction after minor wrist and hand surgery? A randomized observer-blinded trial.

    abstract:BACKGROUND:Patient dissatisfaction has been previously associated with motor block in shoulder surgery patients receiving brachial plexus block. For elective minor wrist and hand surgery, we tested whether a regional block accelerating the early return of upper extremity motor function would improve patient satisfactio...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/bja/aes266

    authors: Fredrickson MJ,Wolstencroft PJ,Chinchanwala S,Boland MR

    更新日期:2012-11-01 00:00:00

  • Quality and outcomes in anaesthesia: lessons from litigation.

    abstract::Healthcare litigation in the UK continues to grow at an alarming rate, with claims against anaesthetists and critical care physicians increasing each year. This has led to a huge financial burden for the taxpayer and a sharp increase in professional indemnity fees for individual doctors. Although such litigation shoul...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aes188

    authors: Adams JP,Bell MD,Bodenham AR

    更新日期:2012-07-01 00:00:00

  • Tracheal intubation after induction of anaesthesia with propofol, alfentanil and i.v. lignocaine.

    abstract::We have assessed tracheal intubating conditions in 60 ASA I or II patients after induction of anaesthesia with propofol 2.5 mg kg-1 and alfentanil 10 or 20 micrograms kg-1 with or without i.v. lignocaine 1 mg kg-1. No neuromuscular blocking agents were administered. Patients were allocated randomly to four groups: gro...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/70.2.163

    authors: Davidson JA,Gillespie JA

    更新日期:1993-02-01 00:00:00

  • Preliminary evaluation of a new prototype laryngeal mask in children.

    abstract::We have assessed a prototype laryngeal mask airway (pLMA) in 50 anaesthetized children for ease of insertion, oropharyngeal leak pressures, gastric insufflation and fibreoptic position. The pLMA has a second smaller mask, which rests against the upper oesophageal sphincter, and a second cuff to increase the seal press...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/82.1.132

    authors: Lopez-Gil M,Brimacombe J,Brain AI

    更新日期:1999-01-01 00:00:00

  • Prospective observational study of the non-invasive assessment of immediate postoperative pain using the analgesia/nociception index (ANI).

    abstract:BACKGROUND:The analgesia/nociception index (ANI), a 0-100 non-invasive index calculated from heart rate variability, reflects the analgesia/nociception balance during general anaesthesia. The aim of this study was to evaluate the ANI in the assessment of immediate postoperative pain in adult patients undergoing general...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aet110

    authors: Boselli E,Daniela-Ionescu M,Bégou G,Bouvet L,Dabouz R,Magnin C,Allaouchiche B

    更新日期:2013-09-01 00:00:00

  • Rhabdomyolysis in an obese patient after total knee arthroplasty.

    abstract::We report the case of a morbidly obese patient who developed rhabdomyolysis with acute renal failure, hepatic dysfunction, and an increase of cardiac troponin-1 after total knee arthroplasty. Postoperative rhabdomyolysis has a wide range of triggers and differential diagnoses that should be considered by the anaesthes...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/ael274

    authors: Karcher C,Dieterich HJ,Schroeder TH

    更新日期:2006-12-01 00:00:00

  • Intravenous infusion of lidocaine significantly reduces propofol dose for colonoscopy: a randomised placebo-controlled study.

    abstract:BACKGROUND:Propofol use during sedation for colonoscopy can result in cardiopulmonary complications. Intravenous lidocaine can alleviate visceral pain and decrease propofol requirements during surgery. We tested the hypothesis that i.v. lidocaine reduces propofol requirements during colonoscopy and improves post-colono...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.bja.2018.06.019

    authors: Forster C,Vanhaudenhuyse A,Gast P,Louis E,Hick G,Brichant JF,Joris J

    更新日期:2018-11-01 00:00:00

  • Use of simple tests to determine the residual effects of the analgesic component of balanced anaesthesia.

    abstract::In order to evaluate simple means of determining the rate of recovery after general anaesthesia, the usefulness of the critical flicker fusion threshold test, the Maddox wing apparatus and the visual analogue scale were compared. The postanaesthetic recovery score was used as a reference. Two patient groups (n = 15 in...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/59.8.978

    authors: Manner T,Kanto J,Salonen M

    更新日期:1987-08-01 00:00:00

  • A comparison of the respiratory effects of meptazinol, pentazocine and morphine.

    abstract::The respiratory effects of a new strong analgesic, meptazinol, were compared with a placebo and with equianalgesic doses of morphine and pentazocine in a double-blind crossover trial in seven healthy volunteers. No significant change in the ventilatory response to rebreathing carbon dioxide was observed after meptazin...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/51.6.497

    authors: Jordan C,Lehane JR,Robson PJ,Jones JG

    更新日期:1979-06-01 00:00:00

  • Prediction of fluid responsiveness in infants and neonates undergoing congenital heart surgery.

    abstract:BACKGROUND:Dynamic variables reliably predict fluid responsiveness (FR) in adults, but no data are available regarding their performance in infants. The aim of this prospective study was to assess whether pulse pressure variation (PPV) and stroke volume variation (SVV), in contrast to central venous pressure (CVP) and ...

    journal_title:British journal of anaesthesia

    pub_type: 杂志文章

    doi:10.1093/bja/aer371

    authors: Renner J,Broch O,Duetschke P,Scheewe J,Höcker J,Moseby M,Jung O,Bein B

    更新日期:2012-01-01 00:00:00

  • Gasless laparoscopic cholecystectomy: comparison of postoperative recovery with conventional technique.

    abstract::We have compared, in a randomized study in 26 patients, immediate and late postoperative recovery after elective laparoscopic cholecystectomy using the gasless, mechanical abdominal wall lift method with conventional carbon dioxide pneumoperitoneum. After the gasless method, tracheal extubation was performed significa...

    journal_title:British journal of anaesthesia

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1093/bja/77.5.576

    authors: Koivusalo AM,Kellokumpu I,Lindgren L

    更新日期:1996-11-01 00:00:00