Abstract：
:Amethocaine 1% solution was mixed with equal volumes of water, 0.9% saline or 10% dextrose to prepare respectively, hypobaric, isobaric and hyperbaric solutions which were compared for intradural spinal anaesthesia in 60 patients. Thirty patients received 10 mg and 30 patients received 15 mg of amethocaine. Injections were made with the patients in the lateral recumbent position and the operating table was horizontal during and after injection. Equal numbers of patients and equal numbers of males and females received hypobaric, isobaric and hyperbaric solutions. The mean spread of analgesia after the hyperbaric solution was five dermatomes greater than after the other two solutions, but the extent of analgesia was not significantly different whether amethocaine 10 mg or 15 mg was injected. The mean duration of analgesia after the hyperbaric solution was 285 min compared with 332 min and 360 min after the isobaric and hypobaric solutions respectively. The mean duration of analgesia after amethocaine 15 mg was significantly greater than after 10 mg.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Brown DT,Wildsmith JA,Covino BG,Scott DBdoi
10.1093/bja/52.6.589subject
Has Abstractpub_date
1980-06-01 00:00:00pages
589-96issue
6eissn
0007-0912issn
1471-6771pii
S0007-0912(17)41786-7journal_volume
52pub_type
临床试验,杂志文章,随机对照试验abstract：:We have compared the anaesthetic and analgesic efficacy of levobupivacaine with that of racemic bupivacaine in 66 male patients undergoing ambulatory primary inguinal herniorrhaphy. Patients were allocated randomly in a double-blind manner to local infiltration anaesthesia (0.25% w/v 50 ml) with either racemic bupivac...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/82.2.280
更新日期：1999-02-01 00:00:00
abstract：:A double-blind crossover volunteer trial has been carried out to determine if oral doxapram reduces the respiratory depression caused by morphine 0.12 mg kg-1 i.m. Doxapram was given to the subjects 90 min before the morphine and significantly reduced the displacement of the ventilatory response to carbon dioxide caus...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/62.2.159
更新日期：1989-02-01 00:00:00
abstract：:Thrombelastography (TEG) correlates with postoperative chest drain output in patients undergoing cardiopulmonary bypass (CPB). In vitro incubation with heparinase allows TEG monitoring during CPB, despite heparin anticoagulation. Hypothermia impairs coagulation, but these effects cannot be assessed by standard coagula...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/80.3.313
更新日期：1998-03-01 00:00:00
abstract：BACKGROUND:Arterial cannulation is a common anaesthetic procedure that can be challenging and time-consuming in small children. By visualizing the position of the radial artery, near-infrared vascular imaging systems (NIRVISs) might be of assistance in arterial cannulation. The present study evaluates the effectiveness...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aes193
更新日期：2012-09-01 00:00:00
abstract：:Intraoperative awareness, with or without recall, continues to be a topic of clinical significance and neurobiological interest. In this article, we review evidence pertaining to the incidence, sequelae, and prevention of intraoperative awareness. We also assess which aspects of the complication are well understood (i...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aev034
更新日期：2015-07-01 00:00:00
abstract：BACKGROUND:Plasma-free volume replacement in haemorrhage often results in dilutional coagulopathy. Prothrombin time index (PTI) and activated partial thromboplastin time (aPTT) are used for monitoring haemostasis but have not yet been clinically evaluated. Our aim was to investigate the effects of haemodilution on the ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeq199
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Double-lumen tubes (DLTs) are frequently used to establish one-lung ventilation (OLV). Their correct placement is crucial. We hypothesized that electrical impedance tomography (EIT) reliably displays distribution of ventilation between left and right lung and may thus be used to verify correct DLT placement ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aen166
更新日期：2008-09-01 00:00:00
abstract：:We studied psychomotor performance in 10 healthy volunteers during recovery after a target-controlled infusion of propofol. Choice reaction time, dual task tracking with secondary reaction time and a within-list recognition task were assessed at target blood propofol concentrations of 0.8, 0.4 and 0.2 microgram ml-1. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/85.3.396
更新日期：2000-09-01 00:00:00
abstract：:We have compared the efficacy of adding varying concentrations of hyaluronidase to a standard mixture of 2% lidocaine and 1% ropivacaine to provide peribulbar anaesthesia for cataract surgery. We used (i) the time to adequate anaesthesia for surgery and (ii) ocular and eyelid movement scores at 8 min after block as cl...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/86.6.876
更新日期：2001-06-01 00:00:00
abstract：:In a prospective study, patients undergoing abdominal surgery were allocated randomly to receive intermittent morphine 10 mg i.m. (n = 41) or a single injection of buprenorphine 0.3 mg i.m. followed by sublingual buprenorphine 0.4 mg every 6 h (n = 39) for 3 days following operation. Patients receiving buprenorphine w...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/56.8.855
更新日期：1984-08-01 00:00:00
abstract：BACKGROUND:The perioperative management of two-stage oesophagectomy has not been standardized and the prevailing practice regarding the timing of extubation after the procedure varies. This audit has evaluated the outcome, in particular the respiratory morbidity and mortality, after immediate extubation in patients who...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeg091
更新日期：2003-04-01 00:00:00
abstract：:We describe a scavenging device, primarily for use during inhalation induction of anaesthesia in children; it was designed to optimize the often conflicting requirements of clinical acceptability and adequate gas collection. The performance was assessed in three ways. The device reduced the nitrous oxide concentration...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/64.1.117
更新日期：1990-01-01 00:00:00
abstract：:We have compared insertion of a tracheal tube and laryngeal mask airway (LMA) both with and without the presence of a tube in the oesophagus in 20 ASA I and II patients undergoing elective laparoscopy. After induction of anaesthesia and neuromuscular block, we measured the times for an experienced anaesthetist to corr...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/73.5.688
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND:Preoperative anaemia affects one third of patients undergoing cardiac surgery and is associated with increased mortality and morbidity. Although it is recommended that perioperative teams should identify and treat patients with preoperative anaemia before surgery, introducing new treatment protocols can be c...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bja.2019.11.023
更新日期：2020-03-01 00:00:00
abstract：:In this study, we have compared two different doses of clonidine (bolus of 25 micrograms and infusion of 19 micrograms h-1; bolus of 50 micrograms and infusion of 37 micrograms h-1, both added to 0.03% bupivacaine) with a control group of 0.03% bupivacaine alone. The study was performed in a randomized, double-blind m...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/83.2.257
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:Inconsistent and poorly coordinated systems of tracheostomy care commonly result in frustrations, delays, and harm. Quality improvement strategies described by exemplar hospitals of the Global Tracheostomy Collaborative have potential to mitigate such problems. This 3 yr guided implementation programme inves...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,多中心研究
doi：10.1016/j.bja.2020.04.064
更新日期：2020-07-01 00:00:00
abstract：:A computer program written mainly in a high level language (ALGOL), but with the sampling routine and certain calculations written in assembly language (SIR), has been developed to assess neuromuscular blockade in anaesthetized man by means of an Elliott 903 digital computer. The program allows the on-line real-time a...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/47.10.1097
更新日期：1975-10-01 00:00:00
abstract：:Forty-five patients undergoing circumcision were allocated randomly to one of three study groups to compare topical analgesia with dorsal nerve block using the midline or lateral approach. Pain scores, side effects and analgesic requirements were recorded after surgery. Patients who received topical analgesia required...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/73.4.437
更新日期：1994-10-01 00:00:00
abstract：BACKGROUND:The 'cannot intubate cannot oxygenate' (CICO) emergency requires urgent front of neck airway (FONA) access to prevent death. In cases reported to the 4th National Audit Project, the most successful FONA was a surgical technique, almost all of which were performed by surgeons. Subsequently, UK guidelines adop...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2019.07.011
更新日期：2019-11-01 00:00:00
abstract：:We compared psychomotor recovery after total intravenous anaesthesia (TIVA) with remifentanil/propofol and balanced anaesthesia (BAL) with etomidate/fentanyl/isoflurane in 40 patients, ASA I-III, aged > or =80 yr undergoing elective cataract surgery. Recovery times were recorded and psychomotor recovery was assessed a...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/86.2.203
更新日期：2001-02-01 00:00:00
abstract：:A total of 1442 patients who had major gynaecological surgery were recruited into three multicentre studies using a standard general anaesthetic technique in order to assess the efficacy of various doses of orally administered ondansetron in the prevention of postoperative nausea and vomiting. A total of 1257 patients...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,meta分析,多中心研究,随机对照试验
doi：10.1093/bja/71.4.517
更新日期：1993-10-01 00:00:00
abstract：:Raised intracranial pressure (ICP) and low cerebral blood flow (CBF) are associated with ischaemia and poor outcome after brain injury. Therefore, many management protocols target these parameters. This overview summarizes the technical aspects of ICP and CBF monitoring, and their role in the clinical management of br...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/ael110
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:Target-controlled infusion (TCI) systems use pharmacokinetic (PK) models to predict the drug infusion rates necessary to achieve a desired target plasma or effect-site concentration. As new PK models are developed and implemented in TCI systems, there can be uncertainty as to which target concentrations are ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1016/j.bja.2020.05.051
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Fast onset and short duration are prominent properties of the amide-type local anaesthetic articaine. Similar to bupivacaine, a hyperbaric solution of articaine may produce faster onset and shorter duration of spinal anaesthesia than a plain solution. METHODS:Patients undergoing open inguinal hernia repair ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aen294
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:The optimal dose of oxytocin at Caesarean section is unclear. Oxytocin may cause adverse cardiovascular effects, including tachycardia and hypotension, whereas an inadequate dose can result in increased uterine bleeding. We compared the effects of two doses of oxytocin in a randomized double-blind trial. ME...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1093/bja/aen273
更新日期：2008-12-01 00:00:00
abstract：:Cancer survivorship represents a growing clinical challenge for pain clinicians. The population of cancer survivors is rapidly expanding and many of these patients experience pain as a sequelae of their disease and its treatment. The features, pathophysiology and natural history of some painful conditions observed in ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,评审
doi：10.1093/bja/aex202
更新日期：2017-10-01 00:00:00
abstract：:A new type of intra-arterial oxygen electrode was evaluated. In 14 patients, undergoing one-lung ventilation for thoracic surgery, the electrode was inserted into the radial artery and changes in PaO2 were recorded continuously. Methods of improving PaO2 during one-lung ventilation were demonstrated. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/48.10.1005
更新日期：1976-10-01 00:00:00
abstract：:Seventy-six Chinese patients aged between 15 and 30 yr, undergoing 3rd molar extraction, were randomly allocated to two groups. One group received halothane and the other isoflurane. The incidence of arrhythmia during surgery under anaesthesia with isoflurane was significantly less than with halothane. Sinus tachycard...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/58.4.394
更新日期：1986-04-01 00:00:00
abstract：:We have examined the correlation between the evoked electromyographic response in the first dorsal interosseous muscle of the hand, temperature and forearm position in 40 female patients after enflurane anaesthesia with spontaneous breathing. In 20 patients the supinated forearm with the wrist extended was immobilized...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/72.4.407
更新日期：1994-04-01 00:00:00
abstract：:We describe a case of a 9-yr-old child with sickle cell disease complicated by abdominal vaso-occlusive crisis and priapism. Both complications were successfully treated with a combination of epidural local anesthetics and morphine. ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/87.6.935
更新日期：2001-12-01 00:00:00
