Abstract：
BACKGROUND:Muscle relaxants facilitate tracheal intubation, but they are often not used for short peripheral surgical procedures. The consequences of this practice on the upper airway are still a matter of controversy. We therefore compared the incidence of post-intubation symptoms in a randomized study comparing patients intubated with or without the use of a muscle relaxant. METHODS:A total of 300 adult patients requiring tracheal intubation for scheduled peripheral surgery were randomly assigned in a double-blind study to an anaesthetic protocol that either included or did not include a muscle relaxant (rocuronium). The primary end-point was the rate of post-intubation symptoms 2 and 24 h after extubation. The secondary end-points were the intubation conditions score (Copenhagen Consensus Conference), the rate of difficult intubations (Intubation Difficulty Scale), and the incidence of adverse haemodynamic events. RESULTS:Post-intubation symptoms were more frequent in patients intubated without the use of a muscle relaxant, whether 2 h (57% vs 43% of patients; P < 0.05) or 24 h (38% vs 26% of patients; P < 0.05) after extubation. Intubation conditions were better when the muscle relaxant was used. In patients intubated without a muscle relaxant, difficult intubation was more common (12% vs 1%; P < 0.05), as were arterial hypotension or bradycardia requiring treatment (12% vs 3% of patients; P < 0.05). CONCLUSIONS:The use of a muscle relaxant for tracheal intubation diminishes the incidence of adverse postoperative upper airway symptoms, results in better tracheal intubation conditions, and reduces the rate of adverse haemodynamic events.
journal_name
Br J Anaesthjournal_title
British journal of anaesthesiaauthors
Combes X,Andriamifidy L,Dufresne E,Suen P,Sauvat S,Scherrer E,Feiss P,Marty J,Duvaldestin Pdoi
10.1093/bja/aem147subject
Has Abstractpub_date
2007-08-01 00:00:00pages
276-81issue
2eissn
0007-0912issn
1471-6771pii
S0007-0912(17)34768-2journal_volume
99pub_type
杂志文章,随机对照试验abstract：BACKGROUND:Ivabradine lowers heart rate (HR) without affecting contractility or vascular tone. It is licensed for HR control in chronic heart diseases. We performed a systematic review and meta-analyses to examine whether ivabradine could decrease major adverse cardiovascular events (MACE) and mortality in critically i...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,meta分析
doi：10.1016/j.bja.2020.01.027
更新日期：2020-06-01 00:00:00
abstract：:The central venous catheter (CVC) is associated with numerous complications more so during the process of insertion. We report for the first time how an indwelling catheter was entrapped by a replacement catheter on the same side, after being speared by the introducer needle and guidewire. The diagnosis was made when ...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/ael286
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abstract：:Muscle biopsy and in vitro contracture tests for diagnosis of susceptibility to malignant hyperthermia (MH) were performed in two patients who had developed fever and severe myolysis during exercise. MH susceptibility was confirmed in one patient, but in the other, exercise-induced heat stroke proved to be the correct...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/66.1.138
更新日期：1991-01-01 00:00:00
abstract：:In a double-blind, randomized study, we have compared the efficacy of transdermal hyoscine in the prevention of nausea and vomiting with placebo in 60 young, ASA I-II patients after middle ear surgery during general anaesthesia. In the placebo group, 27% and 43% of patients suffered from nausea and vomiting, respectiv...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/bja/73.6.763
更新日期：1994-12-01 00:00:00
abstract：BACKGROUND:Forty-eight ASA I-II patients undergoing total abdominal hysterectomy (TAH) were studied in a double blind, randomized placebo controlled trial of parecoxib for postoperative analgesia. METHODS:All patients were given propofol 2-4 mg kg(-1) i.v., a non-depolarizing muscle relaxant, morphine 10 mg i.v. and p...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/76.2.274
更新日期：1996-02-01 00:00:00
abstract：:Robotic surgery pushes the frontiers of innovation in healthcare technology towards improved clinical outcomes. We discuss the evolution to five generations of robotic surgical platforms including stereotactic, endoscopic, bioinspired, microbots on the millimetre scale, and the future development of autonomous systems...
journal_title：British journal of anaesthesia
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doi：10.1093/bja/aex383
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:The aim of this study was to determine the prevalence of postoperative nausea and vomiting (PONV) after fast-track cardiac anaesthesia, risk factors for PONV and its influence on the length of stay in the intensive care unit (ICU). METHODS:A prospective study was performed in the cardiothoracic ICU (CTICU) ...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
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更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:Parecoxib, a cyclo oxygenase-2 inhibiting non-steroidal anti-inflammatory drug, has been widely used for postoperative analgesia. Our aim was to quantify the benefit of a single dose after coronary artery bypass grafting. METHODS:The investigation was carried out as a randomized double blind placebo control...
journal_title：British journal of anaesthesia
pub_type： 杂志文章,随机对照试验
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更新日期：2006-02-01 00:00:00
abstract：:We have examined the effects of two types of insulin therapy (continuous i.v. infusion (group A: 1.25 u. h-1) and direct i.v. bolus administration of 10 u. every 2 h (group B: 10 u./2 h)) on the metabolic and endocrine responses to surgery in 60 adult diabetic patients undergoing general anaesthesia for elective proce...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/72.1.5
更新日期：1994-01-01 00:00:00
abstract：:We calculated oxygen consumption by the reverse Fick principle (cVO2) using cardiac output measured with a new technique of continuous thermal dilution and compared these values with measurements made at the same time using a gas exchange method (mVO2). We studied nine patients in a stable condition after cardiac surg...
journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/75.6.719
更新日期：1995-12-01 00:00:00
abstract：:This is the report of a 55-yr-old female who developed severe myotonia and dystonia after general anaesthesia. Before starting on gabapentin therapy for a neuropathic pain condition, she had undergone numerous uneventful general anaesthetics. Since receiving treatment with gabapentin, she has experienced severe moveme...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aem130
更新日期：2007-08-01 00:00:00
abstract：:A study of core temperature monitoring during general anesthesia indicates that this can be introduced as a routine procedure in order to reduce mortality from malignant hyperpyrexia. The temperature profiles of 2410 patients are presented. Both mean rectal and mean oesophageal temperatures decreased during general an...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/52.12.1223
更新日期：1980-12-01 00:00:00
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeu409
更新日期：2015-04-01 00:00:00
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/50.3.275
更新日期：1978-03-01 00:00:00
abstract：:In this report we present the case of a 77-yr-old man who underwent resection of the upper lobe of the left lung for a carcinoma, six weeks after percutaneous transluminal coronary angioplasty (PTCA) with stenting of the left anterior descending (LAD) and circumflex coronary arteries. Antiplatelet therapy with clopido...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aeh110
更新日期：2004-05-01 00:00:00
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journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
doi：10.1093/bja/47.11.1205
更新日期：1975-11-01 00:00:00
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
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journal_title：British journal of anaesthesia
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pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1998-10-01 00:00:00
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pub_type： 杂志文章
doi：10.1093/bja/60.4.439
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journal_title：British journal of anaesthesia
pub_type： 临床试验,杂志文章
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更新日期：1995-12-01 00:00:00
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/64.5.617
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/aem181
更新日期：2007-09-01 00:00:00
abstract：:The pharmacokinetics of edrophonium were determined in patients anaesthetized with nitrous oxide and halothane undergoing kidney transplant nephrectomy (n=6) or transplantation of a live related donor kidney (n = 6). Serum concentrations of edrophonium were assayed by high pressure liquid chromatography and pharmacoki...
journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/53.12.1311
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
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更新日期：1990-04-01 00:00:00
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journal_title：British journal of anaesthesia
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更新日期：1996-06-01 00:00:00
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journal_title：British journal of anaesthesia
pub_type： 杂志文章
doi：10.1093/bja/ael051
更新日期：2006-05-01 00:00:00
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journal_title：British journal of anaesthesia
pub_type： 杂志文章,撤回出版物
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更新日期：2020-09-01 00:00:00
abstract：:One hundred and six former or current flexible trainees in anaesthesia responded to a questionnaire evaluating their part-time training (a response rate of 71%). They were compared with a group of 32 flexible trainees in obstetrics and gynaecology. Anaesthetists were more satisfied than obstetricians and gynaecologist...
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pub_type： 杂志文章
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更新日期：1998-08-01 00:00:00
