Muscle biopsy for diagnosis of malignant hyperthermia susceptibility in two patients with severe exercise-induced myolysis.

abstract：BACKGROUND:Weaning from mechanical ventilation is a challenging step during recovery from critical illness. Weaning failure or early reintubation are associated with increased morbidity and mortality, exposing patients to life-threatening complications. Cardiac dysfunction represents the most common cause of weaning fa...

journal_title：British journal of anaesthesia

authors： Sanfilippo F,Di Falco D,Noto A,Santonocito C,Morelli A,Bignami E,Scolletta S,Vieillard-Baron A,Astuto M

更新日期：2021-01-01 00:00:00

abstract：:Pyridostigmine 0.143 mg kg-1 (maximum 10 mg) and atropine 0.0143 mg kg-1 (maximum 1 mg) were administered i.v. to six healthy male volunteers. Peripheral venous blood samples were drawn for measurement of serum cholinesterase activity. Maximum inhibition of the enzyme was found 5 min after injection with a decrease to...

journal_title：British journal of anaesthesia

authors： Feldt-Rasmussen BF,Gefke K,Mosbech H,Hanel HK

更新日期：1985-02-01 00:00:00

abstract：:We have evaluated the level of state and trait anxiety, neuroticism, extroversion and coping style as predictors of the effectiveness of patient-controlled analgesia (PCA) in 110 patients undergoing total abdominal hysterectomy. After operation patients were allocated to receive pain control with either PCA or i.m. in...

journal_title：British journal of anaesthesia

authors： Thomas V,Heath M,Rose D,Flory P

更新日期：1995-03-01 00:00:00

abstract：:This study was designed to observe the effects of i.v. fluid infusion on uterine activity during normal labour in women receiving an extradural block. Thirty-four women in spontaneous labour at term gestation were allocated randomly and prospectively to one of three i.v. pre-extradural fluid load groups: group A, no f...

journal_title：British journal of anaesthesia

authors： Cheek TG,Samuels P,Miller F,Tobin M,Gutsche BB

更新日期：1996-11-01 00:00:00

abstract：:Three hundred and twenty adults (ASA grade I, both sexes), received diazepam 10 mg by mouth (50% received atropine 7 micrograms kg-1 in addition) i.m. 45 min before operation. Patients were then allocated randomly to undergo general anaesthesia with either a nitrous oxide-neurolept technique or nitrous oxide-halothane...

journal_title：British journal of anaesthesia

authors： Wierda JM,Maestrone E,Bencini AF,Boyer A,Rashkovsky OM,Lip H,Karliczek R,Ket JM,Agoston S

更新日期：1989-02-01 00:00:00

abstract：:Plasma concentrations of pancuronium were measured using a fluorimetric method in six patients with normal renal function and seven patients in chronic renal failure. A tow-compartment open model was used in the pharmacokinetic analysis of the data. With this model, the clearance of pancuronium was found to be reduce...

journal_title：British journal of anaesthesia

authors： McLeod K,Watson MJ,Rawlins MD

更新日期：1976-04-01 00:00:00

abstract：:The analgesic effects and bioavailability of a slow-release preparation of morphine (Duromorph) were studied in 12 patients with acute postoperative pain. Duromorph produced significant analgesia within 1-2 h of administration i.m., and there was a progressive decrease in the mean pain score for at least 8 h. None of ...

journal_title：British journal of anaesthesia

authors： Charway CL,Calvey TN,Williams NE,Murray GR

更新日期：1985-10-01 00:00:00

abstract：:We present a new pattern of nerve stimulation--double burst stimulation (DBS)--to detect residual neuromuscular block manually. The DBS consists of two short lasting, 50-Hz tetanic stimuli or bursts separated by a 750-ms interval. The response to this pattern of stimulation is two single separated muscle contractions ...

journal_title：British journal of anaesthesia

authors： Engbaek J,Ostergaard D,Viby-Mogensen J

更新日期：1989-03-01 00:00:00

abstract：:We studied 40 elderly patients undergoing cataract surgery. Ten non-insulin-dependent diabetes mellitus (NIDDM) patients received standardized general anaesthesia, 10 NIDDM patients received local anaesthesia using retrobulbar block, 10 non-diabetic control patients received general anaesthesia and 10 non-diabetic con...

journal_title：British journal of anaesthesia

authors： Barker JP,Robinson PN,Vafidis GC,Burrin JM,Sapsed-Byrne S,Hall GM

更新日期：1995-05-01 00:00:00

abstract：:A double-blind randomized trial was conducted to compare etidocaine, the new local anaesthetic agent, with bupivacaine. One hundred patients were each given a single dose of one of the drugs during the surgical induction of labour. The results showed that etidocaine had a quicker onset of action than bupivacaine, but ...

journal_title：British journal of anaesthesia

authors： Phillips G

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:The pulmonary artery catheter is invasive and may cause serious complications. A safe method of cardiac output (CO) measurement is needed. We have assessed the accuracy and reliability of a recently marketed self-calibrating arterial pulse contour CO monitoring system (FloTrac/Vigileo) in end-stage liver fai...

journal_title：British journal of anaesthesia

authors： Biancofiore G,Critchley LA,Lee A,Bindi L,Bisà M,Esposito M,Meacci L,Mozzo R,DeSimone P,Urbani L,Filipponi F

更新日期：2009-01-01 00:00:00

abstract：:We studied 325 patients undergoing elective noncardiac surgery who had preoperative ambulatory ECG monitoring performed for a duration of 5130 h (range 8-24 h; mean 15.8 h). Sixty-four subjects (20%) had one or more episodes of ST segment depression consistent with myocardial ischaemia. Of all preoperative cardiovascu...

journal_title：British journal of anaesthesia

authors： Allman KG,Muir A,Howell SJ,Hemming AE,Sear JW,Foëx P

更新日期：1994-11-01 00:00:00

abstract：:We have investigated 296 inpatients in a single-blind observer study to determine the incidence, degree and duration of hypoxaemia during anaesthesia. The clinical recognition of hypoxaemia, period of time until recognition and risk factors were studied. Oxygen saturation (Spo2) was monitored continuously with a pulse...

journal_title：British journal of anaesthesia

authors： Moller JT,Johannessen NW,Berg H,Espersen K,Larsen LE

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:We describe a practical method of training anaesthetists in the technique of awake fibreoptic intubation. This is performed on a training course using the delegates as subjects. METHODS:The first 15 subjects underwent cardiovascular monitoring during airway fibreoptic endoscopy performed by other course mem...

journal_title：British journal of anaesthesia

authors： Patil V,Barker GL,Harwood RJ,Woodall NM

更新日期：2002-10-01 00:00:00

abstract：:We present a patient with a history of clomipramine-induced serotonin syndrome 5 yr prior who developed serotonin syndrome after a single dose of meperidine. This report heightens appreciation of population at risk and also recognition of potential toxicity in meperidine. ...

journal_title：British journal of anaesthesia

authors： Guo SL,Wu TJ,Liu CC,Ng CC,Chien CC,Sun HL

更新日期：2009-09-01 00:00:00

abstract：:In inflammation, leucocytes containing opioid peptides migrate into the tissue. Opioid peptides can be released and bind to opioid receptors on peripheral nerve terminals, which counteracts inflammatory pain. Migration of opioid peptide-containing leucocytes is controlled by chemokines and adhesion molecules. Neurokin...

journal_title：British journal of anaesthesia

authors： Rittner HL,Brack A,Stein C

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:The population in the UK is growing older and the number of elderly patients cared for on intensive care units (ICU) is increasing. This study was designed to identify risk factors for mortality in critically ill patients of >80 yr of age after surgery. METHODS:We identified 275 patients, aged 80 yr or grea...

journal_title：British journal of anaesthesia

authors： Ford PN,Thomas I,Cook TM,Whitley E,Peden CJ

更新日期：2007-12-01 00:00:00

abstract：:We studied two groups of six patients scheduled for gastrointestinal surgery; they were allocated randomly to receive high- or low-dose fentanyl anaesthesia. The confounding effect of protein balance, before the trauma of surgery, on postoperative nitrogen excretion was controlled by standardized protein intake before...

journal_title：British journal of anaesthesia

authors： Giesecke K,Klingstedt C,Ljungqvist O,Hagenfeldt L

更新日期：1994-06-01 00:00:00

abstract：:Dose-duration relationships for vecuronium were determined and the duration of action produced by vecuronium 0.3 mg kg-1 shown to equal that of pancuronium 0.1 mg kg-1. Using these doses, the neuromuscular blocking properties and cardiovascular effects of the two drugs were compared. With large dose administration of ...

journal_title：British journal of anaesthesia

authors： Rørvik K,Husby P,Gramstad L,Vamnes JS,Bitsch-Larsen L,Koller ME

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Fresh-frozen plasma (FFP) is widely used in critically ill patients, despite a weak evidence base. Factors that influence the decision to transfuse FFP before intravascular catheter insertion are poorly described. METHODS:We undertook a case-controlled study based on a prospective cohort study of 1923 admis...

journal_title：British journal of anaesthesia

authors： Hall DP,Lone NI,Watson DM,Stanworth SJ,Walsh TS,Intensive Care Study of Coagulopathy (ISOC) Investigators.

更新日期：2012-12-01 00:00:00

abstract：:Acute perioperative changes in arterial pressure occur frequently, particularly in patients with cardiovascular disease or those receiving vasoactive medications, or in relation to certain cardiovascular surgical procedures. Both hypo- and hypertension are common in patients undergoing carotid surgery because of uniqu...

journal_title：British journal of anaesthesia

authors： Stoneham MD,Thompson JP

更新日期：2009-04-01 00:00:00

abstract：:Chloral hydrate 25, 50 or 75 mg kg-1 or midazolam 0.4, 0.5 or 0.6 mg kg-1, all given by mouth in combination with atropine 0.03 mg kg-1, were compared as premedication in 248 children in a randomized, double-blind study. Chloral hydrate was significantly less palatable than midazolam. The anxiolytic effect of chloral ...

journal_title：British journal of anaesthesia

authors： Saarnivaara L,Lindgren L,Klemola UM

更新日期：1988-10-01 00:00:00

abstract：:In the dog, pancuronium 0.2 mg/kg increased left ventricular systolic pressure and systemic arterial pressure, but did not change central venous pressure. Repeated doses produced diminishing responses and eventually no change in arterial pressure. After tachyphylaxis was established, a pressor response to pancuronium ...

journal_title：British journal of anaesthesia

authors： Domenech JS,Garcia RC,Sastain JM,Loyola AQ,Oroz JS

更新日期：1976-12-01 00:00:00

abstract：:Metoclopramide has been used for almost 40 yr to prevent postoperative nausea and vomiting (PONV). We have reviewed the efficacy and safety of metoclopramide for the prevention of PONV. A systematic search (MEDLINE, EMBASE, manufacturers' databases, hand searching, bibliographies, all languages, up to June 1998) was p...

journal_title：British journal of anaesthesia

authors： Henzi I,Walder B,Tramèr MR

更新日期：1999-11-01 00:00:00

abstract：:We have studied the effects of alcuronium in 10 healthy, non-anaesthetized volunteers after they had been taking oral pyridostigmine 30 mg 8 hourly. The responses of adductor pollicis were recorded using an isolated forearm procedure (IFP) during onset and recovery of neuromuscular block produced by 1.5 mg of relaxant...

journal_title：British journal of anaesthesia

authors： Turner GA,Williams JD,Baker DJ

更新日期：1991-03-01 00:00:00

abstract：:We have studied 14 female patients undergoing elective laparoscopy under general anaesthesia with peritoneal insufflation of carbon dioxide in order to examine changes in physiological deadspace (VDphys), arterial to end-tidal carbon dioxide partial pressure difference (PaCO2-PE' CO2) and PaCO2. VCO2 increased after i...

journal_title：British journal of anaesthesia

authors： Puri GD,Singh H

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:The safety of performing spinal anaesthesia for both patients and anaesthetists alike in the presence of active infection with the novel coronavirus disease 2019 (COVID-19) is unclear. Here, we report the clinical characteristics and outcomes for both patients with COVID-19 and the anaesthetists who provided...

journal_title：British journal of anaesthesia

authors： Zhong Q,Liu YY,Luo Q,Zou YF,Jiang HX,Li H,Zhang JJ,Li Z,Yang X,Ma M,Tang LJ,Chen YY,Zheng F,Ke JJ,Zhang ZZ

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Priming during anaesthesia has been hard to replicate and the conditions under which it occurs remain poorly understood. We replicated and extended a recent study to determine whether intraoperative priming during propofol and nitrous oxide anaesthesia is a reliable phenomenon, whether it occurs due to aware...

journal_title：British journal of anaesthesia

authors： Deeprose C,Andrade J,Harrison D,Edwards N

更新日期：2005-01-01 00:00:00

abstract：:Recent research has shown that high-frequency, gamma-band electroencephalographic (EEG) oscillations (40-60 Hz) may be an important marker of the conscious state. We compared the ability of the bispectral index (BIS) to distinguish the awake and anaesthetized states during the induction of general anaesthesia with: (i...

journal_title：British journal of anaesthesia

authors： Sleigh JW,Steyn-Ross DA,Steyn-Ross ML,Williams ML,Smith P

更新日期：2001-01-01 00:00:00

abstract：:Five hundred and seventeen women in labour receiving extradural analgesia, using bupivacaine plain solution, were randomly allocated to one of three groups. Group A received 6-8ml of 0.5% solution, group B 10-14ml of 0.25% solution, and group C 6-8 ml of 0.25% solution. Spontaneous delivery occurred in 31.7% of patien...

journal_title：British journal of anaesthesia

authors： Thorburn J,Moir DD

更新日期：1981-09-01 00:00:00