Prevention of nausea and vomiting with transdermal hyoscine in adults after middle ear surgery during general anaesthesia.

abstract：:We have investigated the effect of volatile anaesthetics on protein synthesis and secretion in Hartley male guinea pig liver slices. The slices (250-300 microns thick) were incubated in sealed roller vials containing Krebs-Henseleit buffer at 37 degrees C under 95% oxygen. Volatile anaesthetics were vaporized in the v...

journal_title：British journal of anaesthesia

authors： Ghantous HN,Fernando JL,Keith RL,Gandolfi AJ,Brendel K

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for...

journal_title：British journal of anaesthesia

authors： Zuppa AF,Nicolson SC,Wilder NS,Ibla JC,Gottlieb EA,Burns KM,Stylianou M,Trachtenberg F,Ni H,Skeen TH,Andropoulos DB,Pediatric Heart Network Investigators.

更新日期：2019-12-01 00:00:00

abstract：:Delirium commonly manifests in the postoperative period as a clinical syndrome resulting from acute brain dysfunction or encephalopathy. Delirium is characterized by acute and often fluctuating changes in attention and cognition. Emergence delirium typically presents and resolves within minutes to hours after terminat...

journal_title：British journal of anaesthesia

authors： Palanca BJA,Wildes TS,Ju YS,Ching S,Avidan MS

更新日期：2017-08-01 00:00:00

abstract：:We report an unusual case of acute upper airway obstruction. Inhalation of a foreign body caused choking in a 5-yr-old child, but subsequent investigations revealed a large anterior mediastinal tumour, externally compressing the trachea and the main bronchi. Such a presentation may be deceptive and is important, as ge...

journal_title：British journal of anaesthesia

authors： Akhtar TM,Ridley S,Best CJ

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:As general anaesthesia may compromise the immune system, it has been hypothesized that latent varicella-zoster virus is more likely to be reactivated and cause herpes zoster in mothers after Caesarean deliveries under general anaesthesia. Our study was thus aimed at investigating the risk of herpes zoster am...

journal_title：British journal of anaesthesia

authors： Chen YH,Rau RH,Keller JJ,Lin HC

更新日期：2012-02-01 00:00:00

abstract：:Units for the investigation of susceptibility to malignant hyperthermia (MH) were set up in Denmark in 1977 and in Sweden in 1981. Two hundred and ten patients from 76 families have been investigated. The diagnosis of MH susceptibility (MHS) was made by in vitro exposure of muscle from vastus medialis to halothane and...

journal_title：British journal of anaesthesia

authors： Ording H,Ranklev E,Fletcher R

更新日期：1984-11-01 00:00:00

abstract：:Before the induction of labour in 34 pregnant women 1.5% lignocaine 10 ml was injected into the lumbar extradural space at constant rates between 0.143 and 0.333 ml s-1. Injection pressures and residual pressures were recorded and the extent of analgesia to pinprick was assessed. No significant correlation was found b...

journal_title：British journal of anaesthesia

authors： Husemeyer RP,White DC

更新日期：1980-01-01 00:00:00

abstract：:MHS and normal pigs were anaesthetized with nitrous oxide and diazepam. Halothane 1% was then administered for 1 hr. Immediately before and immediately after the halothane inhalation, 10 g of vastus lateralis muscle was excised. SR was isolated from this muscle. Calcium accumulation by the MHS sarcoplasmic reticulum i...

journal_title：British journal of anaesthesia

authors： Britt BA,Endrenyi L,Cadman DL

更新日期：1975-06-01 00:00:00

abstract：:An investigation was carried out into the relationship between the inflation pressures of normally compliant lungs and the airways pressure necessary to produce the insufflation of gas to the stomach. This relationship was examined during manual ventilation with a mask, using a rapid sequence induction technique. In t...

journal_title：British journal of anaesthesia

authors： Lawes EG,Campbell I,Mercer D

更新日期：1987-03-01 00:00:00

abstract：:We have measured in a double-blind study the changes in intraocular pressure (IOP) in 40 consecutive patients (pretreated with fentanyl or alfentanil) who received suxamethonium and tracheal intubation. Although IOP increased significantly following administration of suxamethonium, mean IOP in both groups remained sig...

journal_title：British journal of anaesthesia

authors： Sweeney J,Underhill S,Dowd T,Mostafa SM

更新日期：1989-12-01 00:00:00

abstract：:Buprenorphine 0.3 mg or fentanyl 0.125 mg i.v. were used to supplement nitrous oxide anaesthesia in a double-blind investigation of 40 patients undergoing major abdominal surgery. Initially both narcotics appeared to suppress tachycardia and increased arterial pressure in response to surgery, but 80% of the patients w...

journal_title：British journal of anaesthesia

authors： Kay B

更新日期：1980-04-01 00:00:00

abstract：:We have compared, in a randomized, double-blind study, the pharmacokinetics of ropivacaine and bupivacaine during labour. Total and free plasma concentrations of ropivacaine and bupivacaine were measured after the first of two extradural doses. The main dose was 20 mg (test dose) and 30 mg, with a top-up dose of 25 mg...

journal_title：British journal of anaesthesia

authors： McCrae AF,Westerling P,McClure JH

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:The ultrasound cardiac output monitor (USCOM) is a continuous wave Doppler system designed to measure cardiac output (CO) non-invasively and intermittently either from the pulmonary or from the aortic valve. USCOM scan quality is critical to obtaining reliable data and during anaesthesia it is said to deteri...

journal_title：British journal of anaesthesia

authors： Huang L,Critchley LA

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:We explored whether a previously successful initiative to improve first-case on-time starts succeeded because (i) preoperative steps started earlier (but the process did not necessarily improve) or (ii) the process was brought into better control. METHODS:We analysed 35 months of data comprising 28 882 firs...

journal_title：British journal of anaesthesia

authors： Tiwari V,Ehrenfeld JM,Sandberg WS

更新日期：2018-11-01 00:00:00

abstract：:To assess the usefulness of the Gram stain in the early diagnosis of ventilator-associated pneumonia (VAP), we performed 146 protected specimen brushings (PSB) and bronchoalveolar lavages (BAL) in 118 patients suspected of having nosocomial pneumonia. Gram stain and counts of infected cells were performed in all sampl...

journal_title：British journal of anaesthesia

authors： Allaouchiche B,Jaumain H,Chassard D,Boulétreau P

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Anaesthetics suppress the formation of lasting memories at concentrations that do not suppress perception, but it is unclear which elements of the complex cascade leading from a conscious experience to a lasting memory trace are disrupted. Experiments in conscious humans suggest that subhypnotic concentratio...

journal_title：British journal of anaesthesia

authors： Pearce RA,Duscher P,Van Dyke K,Lee M,Andrei AC,Perouansky M

更新日期：2012-04-01 00:00:00

abstract：:The Myotest is a new nerve stimulator which can give train-of-four, single twitch (1 and 10 s) and tetanic stimuli. Power is supplied by standard batteries, which allow 200 h effective use. The impulse is unipolar constant current, and the amplitude can be adjusted between 0 and 40 mA. These factors, plus the electron...

journal_title：British journal of anaesthesia

authors： Viby-Mogensen J,Hansen PH,Jørgensen BC,Ording H,Kann T,Fries B

更新日期：1980-05-01 00:00:00

abstract：:Healthcare litigation in the UK continues to grow at an alarming rate, with claims against anaesthetists and critical care physicians increasing each year. This has led to a huge financial burden for the taxpayer and a sharp increase in professional indemnity fees for individual doctors. Although such litigation shoul...

journal_title：British journal of anaesthesia

authors： Adams JP,Bell MD,Bodenham AR

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Pain management in craniotomy patients is challenging, with mild-to-moderate pain intensity, moderate-to-high risk of postoperative nausea and vomiting (PONV), and potentially catastrophic consequences of analgesic-related side-effects. The aim of this study was to determine whether i.v. parecoxib administer...

journal_title：British journal of anaesthesia

authors： Williams DL,Pemberton E,Leslie K

更新日期：2011-09-01 00:00:00

abstract：:Seventy-two adult surgical patients were studied to compare neuromuscular and cardiovascular effects of mivacurium chloride during nitrous oxide-fentanyl-thiopentone (BAL group) or nitrous oxide-halothane (HAL group) anaesthesia. Eighteen patients in the BAL group received an initial bolus of mivacurium, either the ED...

journal_title：British journal of anaesthesia

authors： From RP,Pearson KS,Choi WW,Abou-Donia M,Sokoll MD

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Cardiac output (CO) monitoring is helpful in the assessment of critically ill pregnant women, but invasive monitors are often unsuitable for use. We aimed to measure agreement between the non-invasive ultrasound cardiac output monitor (USCOM) and three-dimensional transthoracic echocardiography (3D-TTE) in p...

journal_title：British journal of anaesthesia

authors： McNamara H,Barclay P,Sharma V

更新日期：2014-10-01 00:00:00

abstract：:We have investigated the effects of 9.5% and 14.1% MAC concentrations of isoflurane on some psychometric measurements. Both concentrations depressed peak saccadic velocity (P < 0.01), choice reaction time (P < 0.05) and visual analogue scores for sedation (P < 0.05), but not the critical flicker fusion threshold. The ...

journal_title：British journal of anaesthesia

authors： Yoshizumi J,Marshall RW,Sanders LD,Vickers MD

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Low fibrinogen (Fg) concentrations in trauma haemorrhage are associated with poorer outcomes. Cryoprecipitate is the standard source for Fg administration in the UK and USA and is often given in the later stages of transfusion therapy. It is not known whether early cryoprecipitate therapy improves clinical o...

journal_title：British journal of anaesthesia

authors： Curry N,Rourke C,Davenport R,Beer S,Pankhurst L,Deary A,Thomas H,Llewelyn C,Green L,Doughty H,Nordmann G,Brohi K,Stanworth S

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:There has been a renewed interest in nitric oxide donor drugs, such as nitroglycerin, delivered by the inhalational route for treatment of pulmonary arterial hypertension (PAH). We investigated the acute effects of inhaled nitroglycerin on pulmonary and systemic haemodynamics in children with PAH associated ...

journal_title：British journal of anaesthesia

authors： Goyal P,Kiran U,Chauhan S,Juneja R,Choudhary M

更新日期：2006-08-01 00:00:00

abstract：:Thirty hypertensive patients scheduled for cholecystectomy or hernia repair under general anaesthesia with thiopentone-fentanyl-nitrous oxide-pancuronium were divided into two groups of 15. One group received metoprolol tablets 200 mg in a slow release form, once daily for at least 2 weeks including the morning of sur...

journal_title：British journal of anaesthesia

authors： Magnusson J,Thulin T,Werner O,Järhult J,Thomson D

更新日期：1986-03-01 00:00:00

abstract：:We have compared the postoperative morphine requirements and analgesic efficacy of four doses of i.m. ketorolac 30 mg administered 6-hourly with placebo in a double-blind study of patients undergoing major or minor orthopaedic surgery. During the 24-h postoperative study period which began at the end of surgery, patie...

journal_title：British journal of anaesthesia

authors： Kinsella J,Moffat AC,Patrick JA,Prentice JW,McArdle CS,Kenny GN

更新日期：1992-07-01 00:00:00

abstract：:The serum concentrations of fazadinium and its metabolites were measured in 14 surgical patients with end-stage renal failure and in 11 patients free from kidney disease undergoing abdominal surgery. A two-compartment open model was used in the pharmacokinetic analysis of the data. The elimination half-life (T 1/2 bet...

journal_title：British journal of anaesthesia

authors： Duvaldestin P,Bertrand JC,Concina D,Henzel D,Lareng L,Desmonts JM

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Investigators planning dose-response studies of neuromuscular blockers have rarely used a priori power analysis to determine the minimal sample size their protocols require. Institutional Review Boards and peer-reviewed journals now generally ask for this information. This study outlines a proposed method fo...

journal_title：British journal of anaesthesia

authors： Kopman AF,Lien CA,Naguib M

更新日期：2011-02-01 00:00:00

abstract：:Raised intracranial pressure (ICP) and low cerebral blood flow (CBF) are associated with ischaemia and poor outcome after brain injury. Therefore, many management protocols target these parameters. This overview summarizes the technical aspects of ICP and CBF monitoring, and their role in the clinical management of br...

journal_title：British journal of anaesthesia

authors： Steiner LA,Andrews PJ

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:One major risk factor of the sitting position for neurosurgery is air embolism, especially in patients with persistent foramen ovale (PFO). The first aim of this prospective study was to evaluate a bedside method for detecting PFO using transcranial Doppler sonography (TCD) with contrast medium. A second aim...

journal_title：British journal of anaesthesia

authors： Engelhardt M,Folkers W,Brenke C,Scholz M,Harders A,Fidorra H,Schmieder K

更新日期：2006-04-01 00:00:00