Monohydroxylated fatty acid content in peripheral blood mononuclear cells and immune status of people at long times after the Chernobyl accident.

abstract：:The retention of 241Am in mice 48 h after administration by gavage is reported here. The 241Am was given to mice in the form of either 241Am nitrate or 241Am citrate. The 241Am was also injected into rats in the same form. The homogenized livers of those rats were subsequently administered by gavage to another group o...

journal_title：Radiation research

authors： Hisamatsu S,Takizawa Y

更新日期：1987-08-01 00:00:00

abstract：:Radiation-induced acute myeloid leukemia (rAML) in C3H mice is commonly developed through inactivation of PU.1 transcription factor encoded in Sfpi1 on chromosome 2. PU.1 inactivation involves two steps: hemizygous deletion of the Sfpi1 gene (DSG) and point mutation of the allele Sfpi1 gene (PMASG). In this study, we ...

journal_title：Radiation research

authors： Ojima M,Hirouchi T,Etani R,Ariyoshi K,Fujishima Y,Kai M

更新日期：2019-12-01 00:00:00

abstract：:Several studies over recent years have highlighted the possibility that radiation can induce transmissible genomic instability. Most of these involve in vitro irradiation and usually in vitro culture. Here it is reported that the short-half-life bone-seeking alpha-particle emitter (224)Ra did not induce excess transmi...

journal_title：Radiation research

authors： Bouffler SD,Haines JW,Edwards AA,Harrison JD,Cox R

更新日期：2001-02-01 00:00:00

abstract：:This review highlights the phenomenon of low-dose hyper- radiosensitivity (HRS), an effect in which cells die from excessive sensitivity to small single doses of ionizing radiation but become more resistant (per unit dose) to larger single doses. Established and new data pertaining to HRS are discussed with respect to...

journal_title：Radiation research

authors： Marples B,Wouters BG,Collis SJ,Chalmers AJ,Joiner MC

更新日期：2004-03-01 00:00:00

abstract：:Tissue oxygenation influences the radiation response of tumors. To further investigate the underlying mechanisms of tumor hypoxia, the spatial distribution of hypoxic cells in relation to the vasculature was studied. In a panel of three human glioma xenograft lines (E2, E102, E106) with different growth characteristic...

journal_title：Radiation research

authors： Rijken PF,Peters JP,Van der Kogel AJ

更新日期：2002-06-01 00:00:00

abstract：:The relationships between DNA damage and the survival of murine bone marrow cells irradiated in situ were examined. Cell survival was assayed by the ability of bone marrow cells from irradiated mice to form colonies in vitro (CFU-C). DNA double-strand breaks (DSBs) were measured by neutral (nondenaturing) filter eluti...

journal_title：Radiation research

authors： Petrovecki M,Prager A,Terry NH,Murray D

更新日期：1994-06-01 00:00:00

abstract：:The purpose of this study was to develop a rat orthotopic lung tumor model with a solitary intrapulmonary nodule to study the effects of high-dose radiation. A549-Luc non-small cell lung cancer (NSCLC) cells were implanted into nude rats in the intercostal space between ribs 5 and 6 of the right lung. Bioluminescence ...

journal_title：Radiation research

authors： Saha D,Watkins L,Yin Y,Thorpe P,Story MD,Song K,Raghavan P,Timmerman R,Chen B,Minna JD,Solberg TD

更新日期：2010-07-01 00:00:00

abstract：:The appearance of prostaglandins and thromboxane in mouse serum after X irradiation was observed by simultaneous quantitative analysis using gas chromatography/mass spectrometry/selected ion monitoring with stable isotope dilution methods. Mice of two strains (C57BL/CN Jcl and BALB/c) showed similar responses to X irr...

journal_title：Radiation research

authors： Yamaoka K,Obata T,Iriyama K,Iwasaki T,Hoshi Y

更新日期：1998-01-01 00:00:00

abstract：:This commentary considers modulation as a factor of potential biological importance in assessment of risk of radiofrequency (RF) energy emitted by communications systems and other technologies. Modulation introduces a spread of frequencies into a carrier waveform, but in nearly all cases this spread is small compared ...

journal_title：Radiation research

authors： Foster KR,Repacholi MH

更新日期：2004-08-01 00:00:00

abstract：:Pregnant Wistar-MS rats received a whole-body irradiation of 0-2.6 Gy gamma rays at day 20 of pregnancy. The mother rats were implanted with a diethylstilbestrol (DES) pellet 30 days after weaning, and the female pups delivered by the irradiated mother were treated with DES after maturation. Lactating rats were irradi...

journal_title：Radiation research

authors： Inano H,Suzuki K,Onoda M,Yamanouchi H

更新日期：1996-06-01 00:00:00

abstract：:An analysis was conducted of 27,982 deaths among 106,020 persons employed at four Federal nuclear plants in Oak Ridge, Tennessee, between 1943 and 1985. The main objectives were to extend the evaluation of the health effects of employment in the nuclear industry in Oak Ridge to include most workers who were omitted fr...

journal_title：Radiation research

authors： Frome EL,Cragle DL,Watkins JP,Wing S,Shy CM,Tankersley WG,West CM

更新日期：1997-07-01 00:00:00

abstract：:The placental transfer and distribution of 241Am in the feto-placental system were studied in pregnant rats. Rats were injected intravenously with 241Am citrate at 15 or 18 days of gestation. Groups injected at 15 days of gestation were sacrificed 2, 24, 48, or 120 hr after injection, and the group injected at 18 days...

journal_title：Radiation research

authors： Hisamatsu S,Takizawa Y

更新日期：1983-04-01 00:00:00

abstract：:It is well established that high-LET radiations efficiently induce chromosome aberrations. However, data on the effect of protons on telomere maintenance, as involved in genomic stability, are scarce and contradictory. Here we demonstrate that high-LET protons induce telomere lengthening in human primary fibroblasts a...

journal_title：Radiation research

authors： Berardinelli F,Antoccia A,Cherubini R,De Nadal V,Gerardi S,Cirrone GA,Tanzarella C,Sgura A

更新日期：2010-11-01 00:00:00

abstract：:Ionizing radiation can induce chromosome instability that is transmitted over many generations after irradiation in the progeny of surviving cells, but it remains unclear why this instability can be transmitted to the progeny. To acquire knowledge about the transmissible nature of genomic instability, we transferred a...

journal_title：Radiation research

authors： Mukaida N,Kodama S,Suzuki K,Oshimura M,Watanabe M

更新日期：2007-06-01 00:00:00

abstract：:We recently reported that daily dietary supplementation with 100 µg selenium (a dose exceeding a rat's nutritional requirement by about 33-fold) initiated immediately after total-body irradiation (TBI) and maintained for 21 weeks mitigates radiation nephropathy in a rat model as indicated by blood urea nitrogen (BUN) ...

journal_title：Radiation research

authors： Sieber F,Muir SA,Cohen EP,Fish BL,Mäder M,Schock AM,Althouse BJ,Moulder JE

更新日期：2011-09-01 00:00:00

abstract：:The detection of (41)Ca atoms in tooth enamel using accelerator mass spectrometry is suggested as a method capable of reconstructing thermal neutron exposures from atomic bomb survivors in Hiroshima and Nagasaki. In general, (41)Ca atoms are produced via thermal neutron capture by stable (40)Ca. Thus any (41)Ca atoms ...

journal_title：Radiation research

authors： Wallner A,Rühm W,Rugel G,Nakamura N,Arazi A,Faestermann T,Knie K,Maier HJ,Korschinek G

更新日期：2010-08-01 00:00:00

abstract：:Metallothionein (MT), the synthesis of which can be induced by metalloelement administration, is a known radical scavenger. This study investigated the possible protective effect of MT against acute radiation injury. Manganese chloride (10 mg of manganese/kg) was administered intraperitoneally to male C3H/He mice 24 h...

journal_title：Radiation research

authors： Murata R,Nishimura Y,Hiraoka M,Abe M,Satoh M

更新日期：1995-09-01 00:00:00

abstract：:To understand the biophysical mechanism(s) underlying the induction of cell death by the decay of the Auger electron emitter iodine-125 in DNA, Chinese hamster V79 lung fibroblasts were labeled with 5-[(125)I]iodo-2'-deoxyuridine ((125)IdU) for two doubling times and frozen and stored at -135 degrees C in the presence...

journal_title：Radiation research

authors： Walicka MA,Ding Y,Adelstein SJ,Kassiss AI

更新日期：2000-09-01 00:00:00

abstract：:To elucidate the nature and kinetics of DNA strand breaks caused by low-energy Auger electron emitters, we compared the yields of DNA breaks in supercoiled pUC19 DNA in the presence of the (.)OH scavenger dimethyl sulfoxide (DMSO) after the decay of (125)I (1) in proximity to DNA after minor-groove binding ((125)I-iod...

journal_title：Radiation research

authors： Kassis AI,Harapanhalli RS,Adelstein SJ

更新日期：1999-11-01 00:00:00

abstract：:Long-term retention of 133Ba in the trachea from intratracheally administered BaSO4 particles was determined by both serial sacrifice and external scanning methods up to 6 months after injection. The amount of 133Ba retained 1 week after injection in the caudal region of the trachea, where the tip of the cannula had b...

journal_title：Radiation research

authors： Takahashi S,Patrick G

更新日期：1987-06-01 00:00:00

abstract：:Resistance to radiation is considered to be an important reason for local failure after radiotherapy and tumor recurrence. However, the exact mechanisms of tumor resistance remain poorly understood. Current investigations of microRNAs as potential diagnostic and therapeutic tools for cancer treatment have shown promis...

journal_title：Radiation research

authors： Mueller AK,Lindner K,Hummel R,Haier J,Watson DI,Hussey DJ

更新日期：2016-06-01 00:00:00

abstract：:Vascular change by the combined treatments of radiation and hyperthermia was studied. The legs of rats were irradiated with 2000 rad of X rays in a single dose and heated at 43.0 degrees C for 1 hr at various times after irradiation, and the blood flow and vascular volume in the skin and muscle were determined with 12...

journal_title：Radiation research

authors： Song CW,Kim JH,Rhee JG,Levitt SH

更新日期：1983-05-01 00:00:00

abstract：:CD34 antigen is a novel marker for human hematopoietic stem/progenitor cells. In the present study, two cell fractions, CD34low and CD34high, were prepared from steady-state human peripheral blood on the basis of CD34 antigen expression. The colony-forming unit megakaryocytes (CFU-Meg) contained in each cell fraction ...

journal_title：Radiation research

authors： Kashiwakura I,Inanami O,Abe Y,Takahashi TA,Kuwabara M

更新日期：2005-07-01 00:00:00

abstract：:The immune response of guinea pigs to Q fever vaccine following 75 to 250 R (60 to 180 rads) of acute whole-body irradiations was investigated. Complement-fixing (CF) antibody titers and protection against febrile response to challenge with virulent Coxiella burnetii were studied. Exposures ranging from 75 to 250 R, 2...

journal_title：Radiation research

authors： Reynolds SL,Whitford HW,Blemly NR,Staab EV,Craig CP

更新日期：1968-10-01 00:00:00

abstract：:Tissue ablation by ultraviolet excimer lasers results in exposure of viable cells to subablative doses of radiation. To understand the potential biological consequences better, we have studied changes in gene expression in cultured human skin fibroblasts exposed to either 193- or 248-nm laser light. Northern blot anal...

journal_title：Radiation research

authors： Rimoldi D,Flessate DM,Samid D

更新日期：1992-09-01 00:00:00

abstract：:Studies have causally linked external thyroid radiation exposure in childhood with thyroid cancer. In 1995, investigators conducted relative risk analyses of pooled data from seven epidemiologic studies. Doses were mostly <10 Gy, although childhood cancer therapies can result in thyroid doses >50 Gy. We pooled data fr...

journal_title：Radiation research

authors： Veiga LH,Holmberg E,Anderson H,Pottern L,Sadetzki S,Adams MJ,Sakata R,Schneider AB,Inskip P,Bhatti P,Johansson R,Neta G,Shore R,de Vathaire F,Damber L,Kleinerman R,Hawkins MM,Tucker M,Lundell M,Lubin JH

更新日期：2016-05-01 00:00:00

abstract：:Determinations of the LET distribution, phi(L), of charged particles within a spacecraft in low-Earth orbit have been made. One method used a cylindrical tissue-equivalent proportional counter (TEPC), with the assumption that for each measured event, lineal energy, y, is equal to LET and thus phi(L) = phi(y). The othe...

journal_title：Radiation research

authors： Doke T,Hayashi T,Borak TB

更新日期：2001-09-01 00:00:00

abstract：:Blockers of the renin-angiotensin-aldosterone system (RAAS) ameliorate cognitive deficits and some aspects of brain injury after whole-brain irradiation. We investigated whether treatment with the angiotensin II type 1 receptor antagonist L-158,809 at a dose that protects cognitive function after fractionated whole-br...

journal_title：Radiation research

authors： Conner KR,Forbes ME,Lee WH,Lee YW,Riddle DR

更新日期：2011-07-01 00:00:00

abstract：:The interaction function gamma(chi), which was introduced in the theory of dual radiation action as the probability that two energy transfers separated by distance chi combine with each other to produce a lesion, was estimated with sparsely ionizing radiation (60Co gamma rays and 40 kV X rays). Gamma(chi) was deduced ...

journal_title：Radiation research

authors： Nenoi M,Kanai T,Ito A

更新日期：1987-10-01 00:00:00

abstract：:A dose-response relationship was established in normal unanesthetized cats for emetic incidence, latency to onset of vomiting, and duration of emetic activity over a period of 24 h after whole-body exposure to 60Co radiation at selected doses between 7.5 and 90 Gy. Each episode of vomiting, i.e., retching and expulsio...

journal_title：Radiation research

authors： Borison HL,McCarthy LE,Douple EB,Johnson J,Borison R

更新日期：1987-03-01 00:00:00