Slow beta-migrating lipoprotein: an atherogenic subclass of low density lipoproteins.

abstract：:The paraoxonases (PON1, PON2 and PON3) are an enzyme family with a high structural homology. All of them have lactonase activity and degrade lipid peroxides in lipoproteins and cells. As such, they play a role in protection against oxidation and inflammation. Infectious diseases are often associated with oxidative str...

journal_title：Clinical biochemistry

authors： Camps J,Iftimie S,García-Heredia A,Castro A,Joven J

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Recently it has been suggested that serum beta-N-acetylhexosaminidase (Hex) could be a joint destruction marker in rheumatoid arthritis (RA) patients. However, a large amount of serum Hex activity has its source from platelets, and the blood platelet-count is often increased in RA, which may have masked the ...

journal_title：Clinical biochemistry

authors： Casal JA,Mera A,Pérez LF,Tutor JC

更新日期：2002-09-01 00:00:00

abstract：:1,5-anhydroglucitol (AG) is a nonmetabolizable glucose analogue found in plasma due to ingestion. The normal steady-state concentration can be dramatically decreased by inhibition of tubular reabsorption during periods of hyperglycemia. For this reason, monitoring of AG has been plausibly advocated for detection of pe...

journal_title：Clinical biochemistry

authors： Nerby CL,Stickle DF

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to measure the extent of lipid peroxidation and the status of antioxidants in patients with Hodgkin's disease. DESIGN AND METHODS:Glutathione peroxidase (GPX) and superoxide dismutase (SOD) activities, and malondialdehyde (MDA), selenium, zinc and copper content have been measu...

journal_title：Clinical biochemistry

authors： Güven M,Oztürk B,Sayal A,Ozet A

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVES:In widely used protocols for the collection and isolation of cord blood mononuclear cells, investigators are left with substantial volumes of diluted plasma which could be used for other measurements. The aim of this study was to ascertain the validity of umbilical cord blood (UCB) diluted plasma samples for...

journal_title：Clinical biochemistry

authors： Albarhani AA,Collier F,Greaves RF,Ponsonby AL,Allen KJ,Vuillermin PJ,Roche P,Clarke MW,BIS Steering Committee.

更新日期：2015-11-01 00:00:00

abstract：:Improving long-term management, life-quality and outcome of transplant recipients continues to be a challenge. The impact of highly chemoattractant proteins as chemokines on transplant outcome is undeniable. These immunoactive molecules are critical in a wide variety of physiological and pathological processes, such a...

journal_title：Clinical biochemistry

authors： Crescioli C

更新日期：2016-03-01 00:00:00

abstract：:Fucosidosis is an inherited lysosomal storage disease due to a deficiency of alpha-L-fucosidase activity. Exponentially growing lymphoid cell cultures from a fucosidosis patient (JH) had 16-fold lower extracellular alpha-L-fucosidase protein and 72-fold lower intracellular alpha-L-fucosidase protein with negligible ca...

journal_title：Clinical biochemistry

authors： DiCioccio RA,Gordon BA

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Determination of metanephrine (MN), normetanephrine (NMN), and 3-methoxytyramine (3-MT) in saliva may offer potential diagnostic advantages in diagnosing pheochromocytoma. METHODS:In this preliminary study, we determined metanephrine concentrations in saliva of healthy subjects and the relationship with sim...

journal_title：Clinical biochemistry

authors： Osinga TE,van der Horst-Schrivers AN,van Faassen M,Kerstens MN,Dullaart RP,Pacak K,Links TP,Kema IP

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:To examine whether the proportions of blood leukocyte subsets are altered in COPD, and to assess the disturbances in signalling pathways in the leukocytes of COPD patients, with respect to smoking history. DESIGN AND METHODS:The study was performed at the Faculty of Pharmacy and Biochemistry and University ...

journal_title：Clinical biochemistry

authors： Rumora L,Milevoj L,Popović-Grle S,Barisić K,Cepelak I,Grubisić TZ

更新日期：2008-04-01 00:00:00

abstract：:Creatine kinase (CK) isoenzymes were determined on 15 patients undergoing open heart surgery with bypass. The study was performed to examine the relationship between the hypothermia under which the surgery is conducted and the appearance of CK isoenzymes in the serum both during and after surgery. All patients showed ...

journal_title：Clinical biochemistry

authors： Devine JE,Spatz LA

更新日期：1982-12-01 00:00:00

abstract：:Several clinical entities are associated with disorders of fatty acid oxidation or transfer across the inner mitochondrial membrane. Over 40 cases of the primary carnitine deficiency syndrome have been reported to date and various subtypes have been characterized. This represents a large clinical spectrum. The deficie...

journal_title：Clinical biochemistry

authors： Angelini C,Trevisan C,Isaya G,Pegolo G,Vergani L

更新日期：1987-02-01 00:00:00

abstract：:The ES 300 (Boehringer Mannheim Diagnostics, Indianapolis, IN) is a new automated immunoassay analyzer intended for the quantitative determination of a wide range of analytes. We compared its performance to enzyme immunoassay (EIA), fluorescence polarization immunoassay (FPIA), and radioimmunoassay (RIA) methods for c...

journal_title：Clinical biochemistry

authors： Camara PD,Velletri K,Krupski M,Rosner M,Griffiths WC

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to establish the range of chitotriosidase (CT) activity in normal individuals, patients with Gaucher disease (GD) and Niemann-Pick disease (NPD), types A or B. The kinetics of CT in these three groups was also investigated. DESIGN AND METHODS:CT activity, as well as Km, Vmax...

journal_title：Clinical biochemistry

authors： Wajner A,Michelin K,Burin MG,Pires RF,Pereira ML,Giugliani R,Coelho JC

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The effectiveness of the URIT-2900 Hematology Analyzer for screening of hemoglobinopathies commonly found in Southeast Asian populations was examined. METHODS:Appropriate cut-off values of MCV and MCH for screening of α(0) and β thalassemias were derived from the receiver operator characteristic curve condu...

journal_title：Clinical biochemistry

authors： Karnpean R,Pansuwan A,Fucharoen G,Fucharoen S

更新日期：2011-07-01 00:00:00

abstract：:Congestive heart failure usually features a mild to moderate increase in aspartate aminotransferase (AST) activity. A marked increase in AST may occur rarely and is usually preceded by prolonged shock or hypotensive episodes and is accompanied by hyperbilirubinemia. I report two patients with congestive heart failure ...

journal_title：Clinical biochemistry

authors： Nanji AA

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the effect of Matrix metalloproteinase 7 -181A/G polymorphism (rs11568818) on the risk of cancer, we performed a meta-analysis. DESIGN AND METHODS:24 case-control studies were identified by searching Pubmed, Embase, ISI, OVID MEDLINE and EBSCO databases. Odd ratios and corresponding 95% confiden...

journal_title：Clinical biochemistry

authors： Wu J,Guan X,Li YT,Bai P,Wu J

更新日期：2013-11-01 00:00:00

abstract：:In order to provide quality control serum in the hypoglycemic range, pooled human serum was treated with yeast. Yeast destroyed about 50% of the serum glucose in about 4 1/2 hrs. The yeast-treated serum remained suitable for quality control of the most commonly analyzed clinical chemistry constituents which showed onl...

journal_title：Clinical biochemistry

authors： Pelletier O,Pryce FH,Logan JE

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVES:The Golgi SNAP receptor complex member 2 (GOSR2) gene is a Golgi-associated soluble factor attachment receptor (SNARE) protein involved in intra-Golgi protein trafficking on chromosome 17q21, which is the hypertension linkage peak on the human chromosome. The aim of the present study was to assess the associ...

journal_title：Clinical biochemistry

authors： Pan S,Nakayama T,Sato N,Izumi Y,Soma M,Aoi N,Ma Y

更新日期：2013-06-01 00:00:00

abstract：:Comparison of the turbidimetric immunoassay of haptoglobin with a reference method (the RID technique with appropriate correction for phenotype) clearly showed the turbidimetric assay to be phenotype-dependent. Correction factors for the three main phenotypes were calculated and reference values determined. The observ...

journal_title：Clinical biochemistry

authors： van Rijn HJ,van der Wilt W,Stroes JW,Schrijver J

更新日期：1987-08-01 00:00:00

abstract：OBJECTIVE:Erythrocyte pyrimidine 5'-nucleotidase (Pyr-5'-N) is highly sensitive to heavy metal inactivation in vitro and in vivo, and a number of studies have verified its usefulness as a biomarker of acute and chronic lead exposures. Retrospective and prospective studies attempted to determine whether the known linear...

journal_title：Clinical biochemistry

authors： Paglia DE,Renner SW,Bhambhani K

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to develop an improved method of direct DNA sequencing, which makes it possible to identify heterozygous mutations of the lipoprotein lipase (LPL) gene in order to understand the underlying genetic disorder of type IV hyperlipoproteinemia. METHODS AND RESULTS:The direct sequenci...

journal_title：Clinical biochemistry

authors： Mori A,Takagi A,Ikeda Y,Yamamoto A

更新日期：1997-06-01 00:00:00

abstract：:The influence of age and disease on serum albumin and alpha-1-acid glycoprotein was studied in 126 subjects (69 M, 57 F) presenting with tuberculosis and after recovery. Albumin concentration fell with age in both disease and healthy states, and alpha-1-acid glycoprotein concentration rose with age in the healthy stat...

journal_title：Clinical biochemistry

authors： Woo J,Chan HS,Or KH,Arumanayagam M

更新日期：1994-08-01 00:00:00

abstract：:Preparation of (14C) Pro labeled protocollagen and requirements for its hydroxylation by PPH was investigated. Protocollagen can be prepared by centrifugation of the biological material at 15.000 X g. Substances in current use, viz catalase, bovine serum albumin and dithiothreitol were found unnecessary under the hydr...

journal_title：Clinical biochemistry

authors： Blumenkrantz N,Asboe-Hansen G

更新日期：1976-12-01 00:00:00

abstract：OBJECTIVES:We established population-based reference limits for plasma total homocysteine (tHcy) according to creatinine. DESIGN AND METHODS:In 7042 middle-aged and elderly subjects from the Hordaland Homocysteine Study, we used statistical modeling to establish nomograms for tHcy according to creatinine in the whole ...

journal_title：Clinical biochemistry

authors： Elshorbagy AK,Oulhaj A,Konstantinova S,Nurk E,Ueland PM,Tell GS,Nygård O,Vollset SE,Refsum H

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:The detection of possible correlation between ribosomal protein RPS27A and multifunctional YB-1 expression in hepatocellular carcinoma (HCC). DESIGN AND METHODS:Tissue microarray slides containing totally 80 cores with 19 tissues of HCC, 1 tissue of hepatocholangiocarcinoma, 10 tissues of liver cirrhosis and...

journal_title：Clinical biochemistry

authors： Gunasekaran VP,Ganeshan M

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To statistically compare and evaluate commonly used methods of estimating reference intervals and to determine which method is best based on characteristics of the distribution of various data sets. DESIGN AND METHODS:Three approaches for estimating reference intervals, i.e. parametric, non-parametric, and r...

journal_title：Clinical biochemistry

authors： Daly CH,Higgins V,Adeli K,Grey VL,Hamid JS

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Plasma ammonia measurement is greatly influenced by pre-analytical conditions, which may lead to false positives. We wanted to evaluate the prevalence and clinical impact of plasma ammonia false positives in a pediatric population. DESIGN AND METHODS:Over a 28-month period, charts of patients with elevated a...

journal_title：Clinical biochemistry

authors： Maranda B,Cousineau J,Allard P,Lambert M

更新日期：2007-05-01 00:00:00

abstract：:1. We compare the Roche ion-exchange column chromatography and the Merck antibody inhibition reaction for CK-MB fractionation in 51 sera. Measurements of total CK and CK-MB activities must be done under the same conditions for each method in order to correlate the results. 2. A decisional value must be used for the in...

journal_title：Clinical biochemistry

authors： Desjarlais F,Daigneault R

更新日期：1979-08-01 00:00:00

abstract：OBJECTIVES:Although monitoring of cyclosporin (CsA) is standard clinical practice postrenal transplantation, mycophenolic acid (MPA) concentrations are not routinely measured. There is evidence that a relationship exists between MPA area under the concentration-time curve (AUC) and rejection. In this study, a retrospec...

journal_title：Clinical biochemistry

authors： Pillans PI,Rigby RJ,Kubler P,Willis C,Salm P,Tett SE,Taylor PJ

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:To develop a tandem mass spectrometry (MS/MS) method for plasma free and total carnitine, incorporating acid hydrolysis for total carnitine measurement, for improved accuracy and sample throughput. DESIGN AND METHODS:Limit of detection (LOD), limit of quantitation (LOQ), linearity, accuracy, precision coeff...

journal_title：Clinical biochemistry

authors： Johnson DW

更新日期：2010-11-01 00:00:00