Abstract：
:A 12-year-old boy with no previous serious medical history experienced abdominal discomfort and chest pains for 5 days and suddenly died. The autopsy revealed diffuse and extensive infiltration of eosinophils into the myocardium, with poorly formed granulomas and few fibrotic changes. The necrotic changes was so extensive that Charcot-Leyden crystals formed. The other visceral organs had no specific pathologic changes except for mild lymphocytic infiltration with an increase in goblet cells in the bronchial areas and eosinocytosis in the blood vessels. An initial viral infection seemed to have caused subsequent eosinophil activation due to an allergic condition. Eosinophilic myocarditis is a rare cause of sudden death in apparently healthy children. Cardiac toxicity of eosinophils is, however, well established and dominates the ultimate prognosis of patients with complicated eosinophilia.
journal_name
Int J Legal Medjournal_title
International journal of legal medicineauthors
Aoki Y,Nata M,Hashiyada M,Sagisaka Kdoi
10.1007/BF01369797subject
Has Abstractpub_date
1996-01-01 00:00:00pages
221-4issue
4eissn
0937-9827issn
1437-1596journal_volume
108pub_type
杂志文章abstract：:The histological staining technique using rhodizonate is also effective for the determination of the firing distance by examining the distribution and intensity of the staining reaction. The differentiation between absolute close-range shots and long-range shots is generally possible without any doubt. The method is n...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100220
更新日期：2002-02-01 00:00:00
abstract：:To determine the cause of death in myocardial ion channel diseases (MICD)-induced sudden cardiac death (SCD) cases is a difficulty in forensic identification practices. The majority of MICD-induced SCD cases would experience lethal ventricular tachyarrhythmia (LVTA) before deaths; thus, confirming the occurrence of LV...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1710-7
更新日期：2018-03-01 00:00:00
abstract：:Y-chromosomal short tandem repeats (Y-STRs) are commonly used to study population histories, discover ancestral relationships, and identify males for criminal justice purposes. Y-STRs being largely in forensic use have low haplotype diversity in some populations and cannot discriminate between paternal male relatives....
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-01997-9
更新日期：2019-05-01 00:00:00
abstract：:Determination of electrolyte concentrations (mainly potassium) in vitreous humour has long been considered an important tool in human death investigations for the estimation of the post-mortem interval (PMI). On the basis of its well known potential in ion analysis, capillary zone electrophoresis (CZE) has recently be...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140100239
更新日期：2002-02-01 00:00:00
abstract：:A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-007-0222-2
更新日期：2008-05-01 00:00:00
abstract：:The accuracy of forensic age estimation based on the chronology of second (M2) and third molar (M3) development was investigated using 2,087 orthopantomograms of Korean men and women aged between 3 and 23 years. The developmental stages of M2s and M3s in these subjects were classified using the criteria of Demirjian. ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0513-x
更新日期：2010-11-01 00:00:00
abstract：:The genetic polymorphisms of 21 autosomal short tandem repeat (STR) loci included in the GlobalFiler™ PCR Amplification Kit were evaluated in 3032 unrelated individuals Altay Han of Xinjiang, northwest China. All of the loci reached the Hardy-Weinberg equilibrium. These loci were examined to determine allele frequenci...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1641-3
更新日期：2018-01-01 00:00:00
abstract：:A study of the genetic variability in the Chueta (Majorcan Jews) and the Balearic (Majorca and Minorca Islands) populations was carried out using a multiplex system containing the nine tetrameric STRs D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820. The Chueta population has remained isolated be...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004149900101
更新日期：2000-01-01 00:00:00
abstract：:Cocaine and alcohol toxicity is well known, especially when simultaneously abused. These drugs perform both acute and chronic harmfulness, with significant cardiac events such as ventricular arrhythmias, tachycardia, systemic hypertension, acute myocardial infarction, ventricular hypertrophy, and acute coronary syndro...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-1119-5
更新日期：2015-01-01 00:00:00
abstract：:In humans, the amelogenin gene is present on both the X and the Y chromosomes. However, there are size differences in this gene between these chromosomes, which have been utilised for sexing in forensic casework and prenatal diagnosis. Our study using the AmpFl STR Profiler Plus kit, showed a deletion of Y chromosome-...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-001-0262-y
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The annual number of detainees held in police custody in France is approximately 700,000. Medical data regarding arrestees are scarce across countries. We present the medical characteristics of detainees kept in police custody, including addictive behaviours and high-risk medical situations. M...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-014-0990-4
更新日期：2014-09-01 00:00:00
abstract：:One of the most fundamental issues in forensic anthropology is the determination of sex and population affinity based on various skeletal elements. Therefore, we compared the sexual dimorphism of the upper facial skeleton from a recent Czech population (twenty-first century) with that of a population from Early Modern...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1625-3
更新日期：2018-01-01 00:00:00
abstract：:We present a duo paternity test case to assess the biological relationship between a woman and her female child. After analyzing 57 autosomal and 19 X-chromosomal short tandem repeat loci, mother-daughter exclusions were discovered at four loci, which were all located on chromosome 2. Further testing of whole-genome s...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-018-1857-x
更新日期：2019-07-01 00:00:00
abstract：:In this study the development of a 13-locus multiplex-PCR system fitting the updated demands for paternity testing in Germany is described. For this purpose an existing multiplex PCR system that allows the simultaneous amplification of eight different STR loci together with the sex-specific locus amelogenin ( genRESMP...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-003-0420-5
更新日期：2004-02-01 00:00:00
abstract：:The in vitro experiments on the interaction of 3H-cocaine and melanin from Sepia officinalis confirmed the existence of drug binding sites on melanin granules. The results suggested that the binding of 3H-cocaine to melanin could be analyzed by assuming that the binding to the surface of pigment granules is analogous ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050031
更新日期：1997-01-01 00:00:00
abstract：:The authors report on a young boy who was bitten into his face by an unknown animal while being asleep in a tent. Given the bite marks and the location of the scene, members of the mustelidae and canidae families were the first "suspects." Deoxyribunucleic acid (DNA) recovered from the tent's wall was analyzed with re...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-012-0674-x
更新日期：2012-05-01 00:00:00
abstract：:The molecular composition of the genetic substrate recovered from seven aged forensic samples has been extensively investigated. A simple enzymatic test based on DNAseI incubation of the extracts showed that the UV-fluorescent material from the forensic specimens is composed of nucleic acids, with the DNA fraction rep...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-002-0326-7
更新日期：2002-12-01 00:00:00
abstract：:The alcoholism marker CDT was determined on 257 blood samples 1-2 days after the blood samples were taken and again after storage for 7 months at +4 degrees C. The differences between the pairs of CDT values were so large that the determination of CDT after long term storage of the blood sample has no evidential value...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050013
更新日期：2000-01-01 00:00:00
abstract：:In forensic science, the unequivocal identification of the cellular origin of crime scene samples used for DNA profiling can provide crucial information for crime scene reconstruction. We have previously shown that various mRNA markers from genes with expression patterns specific for blood and saliva can be establishe...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-008-0249-z
更新日期：2009-01-01 00:00:00
abstract：BACKGROUNDS:Aortic rupture or dissection as immediate cause of sudden death is encountered in forensic and clinical autopsy practice. Despite a common denominator of 'sudden aortic death' (SAD), we expect that in both settings the diagnostic workup, being either primarily legal or primarily disease related, differs sub...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1560-3
更新日期：2017-11-01 00:00:00
abstract：:We present a single case report illustrating the diagnostic role of multi-slice computed tomography (MSCT) in the investigation of suspicious child death where mechanical asphyxia is suspected. The case illustrates how radiological findings that may not be observable on conventional plain X-ray were identified by post...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-010-0438-4
更新日期：2010-11-01 00:00:00
abstract：:The sequences of the hypervariable region 1 (HV1) of the mitochondrial DNA control region from multiple hair shafts from 10 unrelated individuals were compared to determine the frequency of differences in hairs from one individual. The extraction method described herein showed an average success rate of 67% for all 15...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s004140050226
更新日期：1999-01-01 00:00:00
abstract：:Diagnosis of ischaemia-related sudden cardiac death in the absence of microscopic and macroscopic ischaemic lesions remains a challenge for medical examiners. Medical imaging techniques increasingly provide support in post-mortem examinations by detecting and documenting internal findings prior to autopsy. Previous st...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02211-0
更新日期：2020-03-01 00:00:00
abstract：:Messenger RNA (mRNA) markers have been extensively investigated for the identification of forensically relevant body fluids and tissues based on their expression profiles among cell types. As products of the backsplicing of pre-mRNAs, circular RNAs (circRNAs) share exonic sequences with their linear counterparts. The ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02027-y
更新日期：2019-09-01 00:00:00
abstract：:Immunohistochemistry is a well-established technique used in many research laboratories as well as in clinical diagnostics. The method allows to visualize the expression of proteins in biological tissues, as well as to evaluate this expression semi-quantitatively. For diagnosis, an optimal staining, based on a straigh...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1575-9
更新日期：2017-11-01 00:00:00
abstract：:A population study in a sample of 211 unrelated individuals from 2 cities in North and Central Italy was carried out to investigate the short tandem repeat (STR) system HUMVWA31. Separation of PCR- amplified DNA fragments was performed by high-resolution horizontal denaturing polyacrylamide gel electrophoresis (PAGE) ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01428399
更新日期：1995-01-01 00:00:00
abstract：:Allele frequencies and forensic parameters for 17 autosomal short tandem repeat (STR) loci were investigated from 1542 individuals of Va ethnic minority in Yunnan Province in the southwest of China. Also, genetic distances between Va and 13 published populations were compared, and a neighbor-joining (NJ) phylogenetic ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-017-1620-8
更新日期：2017-09-01 00:00:00
abstract：:We have analyzed 11 Y-STR loci (DYS19, the two DYS385 loci, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DXYS156Y) in 700 males from ten ethnic groups in east Asia in order to evaluate their usefulness for forensic and population genetic studies. A total of 644 different haplotypes were identified, among which ...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-004-0518-4
更新日期：2005-07-01 00:00:00
abstract：:In the last decade, increasing knowledge of epigenetics has led to the development of DNA methylation-based models to predict age, which have shown high predictive accuracy. However, despite the value of teeth as forensic samples, few studies have focused on this source of DNA. This study used bisulfite pyrosequencing...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/s00414-019-02242-7
更新日期：2020-03-01 00:00:00
abstract：:Mitochondrial DNA (mtDNA) from 100 unrelated British White Caucasians was extracted, amplified and directly sequenced. Sequences of approximately 800 nucleotides were obtained from 2 hypervariable segments within the non-coding region of the mitochondrial genome. A total of 91 different sequences were observed with an...
journal_title：International journal of legal medicine
pub_type： 杂志文章
doi：10.1007/BF01225046
更新日期：1993-01-01 00:00:00
