Abstract:
:In sections of rat brain treated for Wisteria floribunda agglutinin (WFA) labelling the occurrence of parvalbumin (PARV)-, calbindin (CALB)- or choline acetyltransferase (ChAT) immunoreactivity was analyzed in the basal forebrain using dual-peroxidase and double-fluorescence methods. Only PARV-immunoreactive (-ir) neurons were surrounded by WFA-labelled, i.e. N-acetylgalactosamine-containing, perineuronal lattice-like structures known as perineuronal nets. The distribution of these nets and PARV-ir cells in the rat basal forebrain was documented to obtain detailed data on their co-existence. A remarkable diversity in distribution of both markers was observed, as PARV-ir neurons are only associated with nets in the medial septal nucleus, the nuclei of the diagonal band and the magnocellular preoptic nucleus, but not in the ventral pallidum or the substantia innominata/nucleus basalis complex. These differences in the neuronal microenvironment may reflect system-related specializations of neurons within the basal forebrain nuclei.
journal_name
Brain Resjournal_title
Brain researchauthors
Brauer K,Härtig W,Bigl V,Brückner Gdoi
10.1016/0006-8993(93)91205-7subject
Has Abstractpub_date
1993-12-17 00:00:00pages
167-70issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(93)91205-7journal_volume
631pub_type
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