Abstract：
:The intracellular free Ca2+ concentration ([Ca2+]i) of the bullfrog sympathetic ganglion cell was measured with fura-2 fluorescence under various conditions, and compared with changes in membrane potential recorded with an intracellular electrode. The [Ca2+]i was 109 nM on average under the resting condition and increased by raising the extracellular K+, stimulating repetitively the pre- or post-ganglionic nerve, or by applying acetylcholine or muscarine. Since all these procedures depolarized the cell membrane, most of the rise in [Ca2+]i could be the result of opening of voltage-dependent Ca2+ channels. However, Ca2+ entries through nicotinic acetylcholine receptor channels and the channel activated by the muscarinic acetylcholine receptor were also indicated by considering the threshold for the opening of voltage-dependent Ca2+ channels (for both entries) or a limited number of the cells showing the latter response.
journal_name
Brain Resjournal_title
Brain researchauthors
Nohmi M,Kuba K,Ogura A,Kudo Ydoi
10.1016/0006-8993(88)91336-4subject
Has Abstractpub_date
1988-01-12 00:00:00pages
175-81issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(88)91336-4journal_volume
438pub_type
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