Lasting effects of dopamine receptor agonists upon striatal dopamine release in free-moving rats: an in vivo voltammetric study.

abstract：:Although it has been reported that dendritic neurotransmitter releases from amacrine cells are regulated by the intracellular Ca(2+) concentration ([Ca(2+)](i)), their spatiotemporal patterns are not well explained. Fast Ca(2+) imagings of amacrine cells in the horizontal slice preparation of goldfish retinas under wh...

journal_title：Brain research

authors： Azuma T,Enoki R,Iwamuro K,Kaneko A,Koizumi A

更新日期：2004-10-08 00:00:00

abstract：:Poly(ADP-ribose) polymerase (PARP) can initiate an energy-consuming and inefficient repair cycle following cerebral ischemia/reperfusion by transferring ADP ribose units to nuclear proteins eventually leading to cellular dysfunction and neuronal death. 3-Aminobenzamide (3-AB) is a selective inhibitor of PARP that can ...

journal_title：Brain research

authors： Ding Y,Zhou Y,Lai Q,Li J,Gordon V,Diaz FG

更新日期：2001-10-12 00:00:00

abstract：:Histochemical investigation by means of light and electron microscopy revealed the presence of dipeptidylpeptidase IV activity in Meissner corpuscles of macaque glabrous skin. The enzyme activity was found in fibroblast-like cells forming an incomplete capsule around the Meissner corpuscle. Distinct electron-dense rea...

journal_title：Brain research

authors： Dubový P

更新日期：1988-09-27 00:00:00

abstract：:Our recent researches have identified increased expression of miR-21-5p in rats brain following traumatic brain injury (TBI), which protected against blood-brain barrier (BBB) damage. To further study the mechanism underlying the role of miR-21-5p on alleviating BBB damage after TBI, we performed the scratch injury mo...

journal_title：Brain research

authors： Ge X,Huang S,Gao H,Han Z,Chen F,Zhang S,Wang Z,Kang C,Jiang R,Yue S,Lei P,Zhang J

更新日期：2016-11-01 00:00:00

abstract：:Deposition of beta-amyloid (A beta) is a characteristic feature of the pathology of Alzheimer's disease (AD). Since glucose metabolism and the consequential ATP production are depressed in the temporal and parietal regions of the cortex in patients with AD, we designed the present study to investigate the possible rol...

journal_title：Brain research

authors： Shi J,Xiang Y,Simpkins JW

更新日期：1997-10-24 00:00:00

abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...

journal_title：Brain research

authors： Zhao XC,Zhang LM,Li Q,Tong DY,Fan LC,An P,Wu XY,Chen WM,Zhao P,Wang J

更新日期：2013-11-06 00:00:00

abstract：:Altered expression of neurotrophins may contribute to the pathogenesis of schizophrenia. Several studies suggest sex steroid hormones may be involved in the regulation of brain-derived neurotrophic factor (BDNF) signaling, as well as the symptoms of schizophrenia. This study aimed to identify sex differences in BDNF-T...

journal_title：Brain research

authors： Hill RA,van den Buuse M

更新日期：2011-04-12 00:00:00

abstract：:Preferential uptake of dopamine occurred in mesocortical vs striatal synaptosomes obtained from acutely fighting isolated male ICR mice. Specifically, both Km and Vmax were significantly increased in the prefrontal cortex but not the caudate-putamen. The findings are similar to selective changes in mesocortical activi...

journal_title：Brain research

authors： Hadfield MG

更新日期：1981-10-05 00:00:00

abstract：:Awake, intact monkeys were trained to perform discrete flexion or extension movements of the hand about the wrist in response to visual signals. The object of the movement was to align a cursor, coupled to a manipulandum, on a target line. Cursor and target lines are displayed on a video monitor placed in front of the...

journal_title：Brain research

authors： Murphy JT,Kwan HC,MacKay WA,Wong YC

更新日期：1982-03-25 00:00:00

abstract：:Synaptic strengthening produced by epileptiform activity may contribute to seizure progression and cognitive impairment in epilepsy. Agents that limit this form of plasticity may have therapeutic benefit. Neuregulin is an endogenous growth factor that is released at synapses in an activity dependent manner and can sup...

journal_title：Brain research

authors： Iyengar SS,Mott DD

更新日期：2008-05-07 00:00:00

abstract：:Synaptic glomeruli in the nucleus submedius of the rat are described and the source of some of the component terminals identified. The glomeruli consist of large terminals with round synaptic vesicles establishing Gray type I contacts with dendrites and surrounded by layers of astrocyte derived membranes. The astrocyt...

journal_title：Brain research

authors： Ma W,Ohara PT

更新日期：1987-07-14 00:00:00

abstract：:The local cerebral circulatory and metabolic effects of MK-801, a selective non-competitive N-methyl-D-aspartate receptor antagonist have been examined in conscious rats with quantitative autoradiographic techniques using [14C]iodoantipyrine and [14C]2-deoxyglucose as tracers. Local cerebral blood flow (CBF) and local...

journal_title：Brain research

authors： Nehls DG,Park CK,MacCormack AG,McCulloch J

更新日期：1990-03-19 00:00:00

abstract：:Converging evidence implicates alterations in multiple signaling pathways in the etiology of schizophrenia. Previously, these studies were limited to the analysis of one or a few phosphoproteins at a time. Here, we use a novel kinase array platform to simultaneously investigate the convergence of multiple signaling ca...

journal_title：Brain research

authors： McGuire JL,Hammond JH,Yates SD,Chen D,Haroutunian V,Meador-Woodruff JH,McCullumsmith RE

更新日期：2014-06-03 00:00:00

abstract：:Terminal fibers anterogradely labeled with Phaseolus vulgaris leucoagglutinin (PHA-L) were observed in the locus coeruleus in the brainstem of the cat and the cynomolgus monkey following injections in lamina I of the spinal or medullary dorsal horn. Thus, thermoreceptive- or nociceptive-specific lamina I cells that pr...

journal_title：Brain research

authors： Craig AD

更新日期：1992-07-03 00:00:00

abstract：:The role of thyrotropin releasing hormone (TRH) in the dorsal vagal complex (DVC) in mediating the enhanced gastric contractility induced by glutamate (100 pmol) microinjected into the raphe pallidus (Rpa) was investigated in urethane-anesthetized rats acutely implanted with miniature strain gauge force transducers on...

journal_title：Brain research

authors： Garrick T,Prince M,Yang H,Ohning G,Taché Y

更新日期：1994-02-14 00:00:00

abstract：:The terminal areas and cells of origin of the projection from the dorsal column nuclei to the mesencephalon were investigated by the intra-axonal transport method. Following injection of wheat germ agglutinin-horseradish peroxidase conjugate into the dorsal column nuclei, anterograde labeling was observed in several r...

journal_title：Brain research

authors： Wiberg M,Blomqvist A

更新日期：1984-10-08 00:00:00

abstract：:Retinal lesions in pigeons produced a marked depletion of somata and neuropil staining for both calbindin-D28k and parvalbumin immunoreactivities in the contralateral optic tectum. Calbindin-like immunoreactivity reappeared in some tectal layers by 6 weeks postlesion, whereas paravalbumin-like immunoreactivity recover...

journal_title：Brain research

authors： Britto LR,Gobersztejn F,Karten HJ,Cox K

更新日期：1994-10-24 00:00:00

abstract：:Multiple lines of evidence indicate that hypocretin/orexin (HCRT) participates in the regulation of arousal and arousal-related process. For example, HCRT axons and receptors are found within a variety of arousal-related systems. Moreover, when administered centrally, HCRT exerts robust wake-promoting actions. Finally...

journal_title：Brain research

authors： Berridge CW,España RA,Vittoz NM

更新日期：2010-02-16 00:00:00

abstract：:An enriched environment has been shown to improve cognitive, behavioral and histopathological outcome after focal cerebral ischemia and head trauma. The purpose of this study was to determine the effect of an enriched environment on histopathology following global cerebral ischemia. Wistar rats (21 weeks of age) were ...

journal_title：Brain research

authors： Belayev A,Saul I,Liu Y,Zhao W,Ginsberg MD,Valdes MA,Busto R,Belayev L

更新日期：2003-02-21 00:00:00

abstract：:Neurokinin A and B (NKA and NKB) and neuropeptide K (NPK) were recently isolated from porcine spinal cord and brain, and together with substance P (SP) considerably extend the list of tachykinin-like peptides present in the mammalian nervous system. In order to investigate the distribution of tachykinins in the centra...

journal_title：Brain research

authors： Arai H,Emson PC

更新日期：1986-12-10 00:00:00

abstract：:We have previously raised a monoclonal antibody (69A1) which recognises a cell-surface antigen expressed on rat cerebellar neurons both in culture and in tissue sections of the developing cerebellum prior to postnatal day 17. In our current study we have undertaken a detailed analysis of the loss of labelling from the...

journal_title：Brain research

authors： Pigott R,Kelly JS

更新日期：1986-09-01 00:00:00

abstract：:Axotomy produced an increase in the spike width and a decrease in amplitude of the afterhyperpolarization which followed the action potential in C-cells of bullfrog sympathetic ganglia. Although no change in B-cell conduction velocity was noted, C-cell conduction velocity increased significantly and approached that of...

journal_title：Brain research

authors： Shapiro J,Gurtu S,Gordon T,Smith PA

更新日期：1987-04-28 00:00:00

abstract：:Muscarinic and NMDA receptors contribute to post-traumatic hypersensitivity to secondary ischemia. However, the effect of these receptor antagonists on behavior and CA1 neuronal death after traumatic brain injury (TBI) with acute (1 h after TBI) forebrain ischemia has not been systematically assessed. We examined cogn...

journal_title：Brain research

authors： Jenkins LW,Lu Y,Johnston WE,Lyeth BG,Prough DS

更新日期：1999-01-30 00:00:00

abstract：:This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...

journal_title：Brain research

authors： Foster TC,Fugger HN,Cunningham SG

更新日期：2000-07-14 00:00:00

abstract：:Electroacupuncture (EA) has been reported to alleviate motor deficits in Parkinson's disease (PD) patients, and PD animal models. However, the mechanisms by which EA improves motor function have not been investigated. We have employed a 6-hydroxydopamine (6-OHDA) unilateral injection induced PD model to investigate wh...

journal_title：Brain research

authors： Li M,Li L,Wang K,Su W,Jia J,Wang X

更新日期：2017-10-15 00:00:00

abstract：:The neurotrophic effect of bFGF on dopamine (DA) neurons in vitro depends upon its mitogenic activity on glial cells. We examined whether glial secretion of the dopaminergic growth factor GDNF is responsible for the trophic activity of bFGF on mesencephalic DA neurons. When added with lower concentrations of bFGF, GDN...

journal_title：Brain research

authors： Hou JG,Mytilineou C

更新日期：1996-06-10 00:00:00

abstract：:Previous observations show that neonatal removal of nerve growth factor results in an increased number of fine dorsal root axons in the adult animal. The present study shows that the same treatment results in 49% more axons in the adult tract of Lissauer, which is an area of spinal white matter that contains predomina...

journal_title：Brain research

authors： Hulsebosch CE,Coggeshall RE

更新日期：1988-10-04 00:00:00

abstract：:The prostacyclin (PGI2) formation in cerebral vessels, as reflected by the difference in concentration of internal carotid arterial and internal jugular venous radioimmunoassayed 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), was determined under normocapnic and hypercapnic conditions in 5 patients with mild cereb...

journal_title：Brain research

authors： Uyama O,Nagatsuka K,Fukunaga R,Kusunoki M,Takano T,Yoneda S,Kimura K,Abe H

更新日期：1983-01-24 00:00:00

abstract：:Insulin has emerged as an important neuropeptide. Central actions of insulin appear to oppose those in the periphery. Insulin is transported across the blood-brain barrier (BBB) by a saturable transport system. The permeability of the BBB to insulin is altered by various events, but no studies exist that have examined...

journal_title：Brain research

authors： Xaio H,Banks WA,Niehoff ML,Morley JE

更新日期：2001-03-30 00:00:00

abstract：:Social defeat is a powerful experience that often leads to drastic physiological and behavioral changes in many animal species. An example of such a change is conditioned defeat in Syrian hamsters. The neurophysiological mechanisms that underlie such changes are not yet fully understood, however, there is evidence tha...

journal_title：Brain research

authors： Jasnow AM,Huhman KL

更新日期：2001-11-30 00:00:00