Abstract:
:Microbeam X-ray spectrometry, energy-dispersive X-ray fluorescence analysis, and neutron activation analysis were evaluated for the detection of selenium contained in the selenoprotein glutathione peroxidase. The glutathione peroxidase had been previously separated using polyacrylamide gel electrophoresis. The use of Bragg-reflected polarized X-ray beams was employed in the X-ray fluorescence measurements to minimize the problem of scatter owing to the gel matrix. Current detection limits of selenium in a gel matrix are 2.1 ng in the bench-top microbeam X-ray system and 30-60 ng using XRF with polarized beams. Neutron activation analysis was used for quality-control measurements, with a detection limit here of < 0.08 ng. The work has in principle established the feasibility of such an approach.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Stone SF,Bernasconi G,Haselberger N,Makarewicz M,Ogris R,Wobrauschek P,Zeisler Rdoi
10.1007/BF02917328subject
Has Abstractpub_date
1994-10-01 00:00:00pages
299-307eissn
0163-4984issn
1559-0720journal_volume
43-45pub_type
杂志文章abstract::CuO nanoparticles (CuO-NPs) serve several important functions in human life, particularly in the fields of medicine, engineering, and technology. These nanoparticles have been utilized as catalysts, semiconductors, sensors, gaseous and solid ceramic pigments, and magnet rotatable devices. Further use for CuO-NPs has b...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1170-4
更新日期:2018-08-01 00:00:00
abstract::Tungstate is an oxyanion that has biological similarities to vanadate. In recent years, a number of studies have shown the antidiabetic effects of oral tungstate in animal models of diabetes. However, because of the tissue accumulation and potential toxicity derived from chronic administration of vanadium and tungsten...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1385/BTER:88:2:097
更新日期:2002-08-01 00:00:00
abstract::The distribution and chemical species of iodine in various subcellular fractions of human liver were studied by using epithermal neutron activation analysis combined with chemical and biochemical separation techniques, such as gradient centrifugation and gel chromatography. It was found that the total iodine content o...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783916
更新日期:1999-07-01 00:00:00
abstract::The phosphorus NMR profile of normal and vanadium-treated chick muscle was obtained in vivo. The data show that the differentiation of breast and thigh muscles in terms of pH, lipid related metabolites, and bioenergetic parameters can be readily followed. Although the vanadium-treated chicks showed substantial retarda...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990427
更新日期:1991-11-01 00:00:00
abstract::To investigate the protective effect of garlic powder on cadmium-induced toxicity sea bass liver, juvenile fishes where maintained under three food diets (diet 1: normal without garlic supply, diet 2: 2% garlic powder; diet 3: 6% garlic powder). After 30 days of specific diets, each group was injected with 500 μg kg-1...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1146-4
更新日期:2018-06-01 00:00:00
abstract::The key role of osteoblasts in skeletal fluorosis makes the exploration of the possible mechanisms of the fluoride-induced oxidative stress of osteoblasts of great importance. In this article, the in vitro effects of fluoride on the oxidative stress of osteoblasts are presented. To study the inhibitory effect of baica...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02685921
更新日期:2007-04-01 00:00:00
abstract::Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease of multifactorial origin. Studies have shown that trace elements such as zinc and copper may help maintain optimum function of the immune system and metabolism, while toxic metals such as lead may increase systemic autoimmunity. The curren...
journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
doi:10.1007/s12011-018-1592-7
更新日期:2019-09-01 00:00:00
abstract::To elucidate whether the accumulation of elements occurred simultaneously in the various arteries with aging, the authors investigated age-related changes of elements in the eight arteries, such as the thoracic and abdominal aortas and the coronary, common carotid, pulmonary, splenic, common iliac, and uterine arterie...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02698081
更新日期:2007-07-01 00:00:00
abstract::To obtain real-time dynamic changes of non-protein-bound copper in the blood, we have developed an online microdialysis sampling system coupled with a flow-injection graphite furnace-atomic absorption spectrometer (FI-GFAAS). The analytical performances of the online system such as linearity, limit of detection, preci...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:111:1:255
更新日期:2006-07-01 00:00:00
abstract::Age-related changes in the concentrations of constituent elements in the brains of rats and mice 1 wk to 24 mo old were determined with inductively coupled plasma-mass spectrometry (ICP-MS) and inductively coupled plasma-atomic emission spectrometry (ICP-AES). Seventeen elements could be determined with reasonable acc...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:80:2:145
更新日期:2001-05-01 00:00:00
abstract::In this study, hair levels of Cu and Zn were determined in healthy male and female individuals (n = 192) ages 3.6-14.5 yr and the correlations with Cu and Zn daily intakes were examined. Determinations of Cu and Zn concentrations were performed by way of atomic absorption spectrometry and X-ray fluorescence. Nutrition...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02950788
更新日期:1994-02-01 00:00:00
abstract::It has become evident over the last two decades that there is an intimate relationship between the trace elements and cancer. Some trace elements have been shown to be carcinogens, others appear to provide protection against cancer. Profound changes in trace element concentrations and distribution occur in patients wi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783817
更新日期:1979-08-01 00:00:00
abstract::Lead is a biohazardous metal that is commonly involved in human illness including renal injury. Although it is a non-redox reactive metal, lead-induced renal injury is largely based on oxidative stress. The current work aimed at exploring the possible protective effect of γ-glutamyl cysteine (γGC) against lead-induced...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-016-0624-4
更新日期:2016-09-01 00:00:00
abstract::Many studies have shown that zinc deficiency could decrease the response to insulin. In genetically diabetic animals, a low zinc status has been observed contrary to induced diabetic animals. The zinc status of human patients depends on the type of diabetes and the age. Zinc supplementation seems to have beneficial ef...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/BF02784615
更新日期:1992-01-01 00:00:00
abstract::The effects of 10 wk of selenium (Se) supplementation (5 ppm) in drinking water on immune responses and resistance to a myocarditic Coxsackie virus B3 (CB3) infection were studied in female Balb/c mice. Se supplementation reduced CB3-induced mortality: at day 14 postinoculation, survival was 58% in the Se-treated grou...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785277
更新日期:1998-07-01 00:00:00
abstract::The effect of low copper and high zinc intakes on Cu,Zn-superoxide dismutase (Cu,Zn-SOD) activity and mammary tumorigenesis induced by 9,10-dimethyl-1,2-benzanthracene (DMBA) was investigated. Groups of 40 weanling female Sprague-Dawley rats were fed a modified AIN-76 diet containing the following (/kg diet): 1 mg Cu ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990343
更新日期:1991-07-01 00:00:00
abstract::The effects of zinc chloride (ZnCl2), disodium zinc ethylenediamine tetraacetate (Zn-EDTA), and zinc gluconate (Zn-GLU) on the antioxidant enzyme activities and levels of interleukins (ILs) in psoriasis-induced mice were studied. One hundred twenty female mice were randomly divided into six groups with 20 mice in each...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9799-0
更新日期:2013-12-01 00:00:00
abstract::The biological function of selenium (Se) is mainly elicited through Se-containing proteins. Selenoprotein W (SelW), one member of the selenoprotein family, is essential for the normal function of the skeletal muscle system. To investigate the possible relationship of Se in the process of differentiation in chicken myo...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9520-8
更新日期:2012-12-01 00:00:00
abstract::Studies investigating the effects of Chromium (Cr) supplementation on unstressed broiler chickens have reported an inconsistent association between Cr supplementation and broiler chickens' responses. We conducted a dose-response meta-analysis of previous studies to assess the dose-response associations between Cr supp...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-021-02589-2
更新日期:2021-01-17 00:00:00
abstract::Selenium is an essential nutrient in diets; however, the effects of selenium on enzyme metabolic activation are not currently clear. Cytochromes P450 (CYP450) are major phase I metabolic enzymes involved in the biotransformation of xenobiotics and endogenous compounds to form electrophilic reactive metabolites. To inv...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-019-01945-7
更新日期:2020-08-01 00:00:00
abstract::Two organoselenium compounds: xylitol selenious ester (xylitol-Se) and sucrose selenious ester (sucrose-Se) were synthesized, and their molecular structures were characterized in this study. In MTT assay, xylitol-Se and sucrose-Se showed cytostatic effects on human hepatocellular carcinoma cells SMMC-7221 in a dose-de...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9715-7
更新日期:2013-08-01 00:00:00
abstract::Recently, several studies on the effects of a compound named "chromium malate," with the proposed formula "Cr2malate3·xH2O" where x = 3.5 or 5, on the health of healthy and diabetic rats have appeared. However, the compound is poorly characterized, and knowing the identity of this material could be important in the in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1046-7
更新日期:2018-02-01 00:00:00
abstract::Variations in trace element concentration in the head and facial hair of five individuals with ever-increasing amounts of white hair were examined. Hair was collected from the scalp, cheeks, and chin from one donor on a regular basis since 1984. Samples were separated into white and pigmented fractions, and analyzed a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992728
更新日期:1990-07-01 00:00:00
abstract::The chronic exposure to Aluminum (Al) may compromise different liver functions, mainly during the hepatic regeneration. The aim of this study is to investigate the interactions between the chronic i.p. exposure to Al and hepatic regeneration (HR) on bile flow and organic anion transport in experimental animals. For th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-008-8234-4
更新日期:2009-02-01 00:00:00
abstract::This study was to investigate the alterations of serum copper homeostasis after hypertensive intracerebral hemorrhage (ICH), which is not yet clear. We recruited 85 hypertensive ICH patients and determined their serum levels of total copper (TCu), small molecule copper (SMC), and ceruloplasmin (Cp). Sera from 32 healt...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-017-1227-4
更新日期:2018-09-01 00:00:00
abstract::A rapid cyclic instrumental neutron activation analysis (CINAA) method has been used to determine the selenium content of 27 duplicate diet samples from each of the 27 districts surrounding Pinhel, Portugal. The accuracy and precision of the CINAA method have been evaluated by analyzing certified reference materials a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992719
更新日期:1990-07-01 00:00:00
abstract::Vanadium compounds maintain euglycemic effects in diabetic rats long after drug withdrawal and bis(α-furancarboxylato)oxovanadium(IV) (BFOV) possesses potent antidiabetic effects in diabetic rats. Here, we investigated the treatment and posttreatment effects of BFOV in diabetic Kuo Kondo [1, 2] with Ay gene (KKAy) mic...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9689-5
更新日期:2013-06-01 00:00:00
abstract::Human ocular tissues from 50 donor eyes were elementally and morphologically analyzed in order to correlate the elemental content and distribution of Ca, Ba, Cr, Cu, Zn, and Se with ocular morphology, sex, race, irideal pigmentation, age, time of death, birth weight, presence and severity of diabetes, and other pathol...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02796667
更新日期:1987-04-01 00:00:00
abstract::Inducing the differentiation of stem cells from human exfoliated deciduous teeth (SHEDs) proceeds with low efficiency, which greatly limits clinical applications. Divalent metal elements play an important role in osteoinductivity for bone remodeling because they can simulate bone formation and decrease bone resorption...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1256-7
更新日期:2018-10-01 00:00:00
abstract::Lipid disturbance induced by high-fat diet is a worldwide problem, and it can induce inflammation and oxidative stress in vivo. Zinc is considered as an antioxidant, anti-inflammatory agent. Since matrix metalloprotease 2 (MMP2) and matrix metalloprotease 9 (MMP9)'s expressions are changed under many pathological cond...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0367-7
更新日期:2015-12-01 00:00:00